المؤلفون: Radka Hobzova, Jakub Sirc, Kusum Shrestha, Barbora Mudrova, Zuzana Bosakova, Miroslav Slouf, Marcela Munzarova, Jan Hrabeta, Tereza Feglarova, Ana-Irina Cocarta

المصدر: Pharmaceutics, Vol 15, Iss 5, p 1398 (2023)

مصطلحات موضوعية: nanofibers, needleless electrospinning, multilayered structure, topotecan, prolonged release, retinoblastoma, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/5/1398; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/dc055db59e3d4d1d96a4cddc19945925

المؤلفون: Kateřina Jáklová, Tereza Feglarová, Simona Rex, Zbyněk Heger, Tomáš Eckschlager, Jan Hraběta, Petr Hodek, Matúš Kolárik, Radek Indra

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 8, p 4250 (2021)

مصطلحات موضوعية: vandetanib, apoferritin, neuroblastoma, medullary thyroid cancer, cancer targeting, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/22/8/4250; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/396c504b67bd4c449cfa0abb83b41c12

المؤلفون: Jan Hraběta, Marie Belhajová, Hana Šubrtová, Miguel Angel Merlos Rodrigo, Zbyněk Heger, Tomáš Eckschlager

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 12, p 4392 (2020)

مصطلحات موضوعية: chemoresistance of cancer cells, lysosomal sequestration, V-ATPase, metallothioneins, lysosomotropic agents, V-ATPase inhibitors, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/21/12/4392; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/2a64c230c017427d8d42287fa6476bfb

المؤلفون: Mohamed Ashraf Khalil, Jan Hraběta, Tomáš Groh, Pavel Procházka, Helena Doktorová, Tomáš Eckschlager

المصدر: PLoS ONE, Vol 11, Iss 9, p e0162916 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5023141?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/b1b3cf3f9c5c4093b1441c122357d8f1

المؤلفون: Miguel Angel Merlos Rodrigo, Jan Hraběta, Tomas Eckschlager, Hana Šubrtová, Zbyněk Heger, Marie Belhajová

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 4392, p 4392 (2020)
International Journal of Molecular Sciences. 2020, vol. 21, issue 12, p. 1-18.
International Journal of Molecular Sciences

مصطلحات موضوعية: 0301 basic medicine, Drug, Vacuolar Proton-Translocating ATPases, metallothioneins, media_common.quotation_subject, Antineoplastic Agents, V-ATPase, Review, Drug resistance, lysosomotropic agents, Exocytosis, Catalysis, Inorganic Chemistry, lcsh:Chemistry, 03 medical and health sciences, 0302 clinical medicine, Chloroquine, Cell Line, Tumor, Neoplasms, chemoresistance of cancer cells, medicine, Humans, V-ATPase inhibitors, Physical and Theoretical Chemistry, Molecular Biology, lcsh:QH301-705.5, Spectroscopy, media_common, lysosomal sequestration, Chemistry, Organic Chemistry, General Medicine, Hydrogen-Ion Concentration, Computer Science Applications, Gene Expression Regulation, Neoplastic, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Lysosomes, Tyrosine kinase, Intracellular, medicine.drug

وصف الملف: text; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288942c58c306d3382e345d01f2d37ce
https://www.mdpi.com/1422-0067/21/12/4392

المؤلفون: Marketa Martinkova, Marek Wilhelm, Alžběta Lengálová, Volker M. Arlt, Zbyněk Heger, Simona Dostalova, Heinz H. Schmeiser, Tomas Eckschlager, Tereza Cerna, Radek Indra, Marie Stiborová, Vojtěch Adam, Jan Hraběta

المصدر: Indra, R, Černá, T, Heger, Z, Hraběta, J, Wilhelm, M, Dostálová, S, Lengálová, A, Martínková, M, Adam, V, Eckschlager, T, Schmeiser, H H, Arlt, V M & Stiborová, M 2019, ' Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells ', Toxicology, vol. 419, pp. 40-54 . https://doi.org/10.1016/j.tox.2019.03.009

مصطلحات موضوعية: 0301 basic medicine, Cell Survival, Drug Compounding, Cytotoxicity, Antineoplastic Agents, Toxicology, Histones, 03 medical and health sciences, chemistry.chemical_compound, DNA Adducts, Neuroblastoma, 0302 clinical medicine, Cell Line, Tumor, DNA adduct, Water environment, Cytochrome P-450 CYP3A, Humans, Ellipticines, Phosphorylation, chemistry.chemical_classification, Drug Carriers, Cytochrome P450-mediated metabolism, biology, Chemistry, Ellipticine, Cytochrome P450, DNA adducts, Apoferritin nanoparticles, Drug Liberation, 030104 developmental biology, Enzyme, Apoferritins, Microsome, Biophysics, biology.protein, Nanoparticles, Nanocarriers, 030217 neurology & neurosurgery, DNA

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410e55f7c653c5e908a9253ffea492f1
https://kclpure.kcl.ac.uk/ws/files/107877103/Indra_etal_Toxicology_2019.pdf

المؤلفون: Tomas Eckschlager, Ladislav Sivák, Lucie Cuchalová, Jan Hraběta, Zuzana Hvězdová, Eva Koziolová, Karel Ulbrich, Tomáš Etrych, Vladimir Subr, Olga Janoušková

المصدر: Journal of Controlled Release. 233:136-146

مصطلحات موضوعية: Cell Survival, Pirarubicin, Pharmaceutical Science, 02 engineering and technology, Pharmacology, Neuroblastoma, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Humans, Doxorubicin, ATP Binding Cassette Transporter, Subfamily B, Member 1, Cytotoxicity, P-glycoprotein Inhibitor, Antibiotics, Antineoplastic, Ritonavir, Chemistry, Biological activity, 021001 nanoscience & nanotechnology, Drug Resistance, Multiple, In vitro, Multiple drug resistance, Drug Liberation, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Methacrylates, 0210 nano-technology, Oligopeptides, medicine.drug, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f98e48e397c24c15e8fda9d3540b04b
https://doi.org/10.1016/j.jconrel.2016.05.036

المؤلفون: Jan Hraběta, Jana Hřebačková, Tomas Eckschlager, Jitka Poljaková, Simon Cipro

المصدر: Oncology Reports

مصطلحات موضوعية: Cancer Research, Time Factors, medicine.drug_class, Cell Survival, Biology, Caspase 8, chemistry.chemical_compound, Neuroblastoma, Annexin, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, In Situ Nick-End Labeling, Humans, Propidium iodide, Cisplatin, TUNEL assay, Dose-Response Relationship, Drug, hypoxia, Valproic Acid, Histone deacetylase inhibitor, apoptosis, Drug Synergism, General Medicine, Articles, medicine.disease, Hypoxia-Inducible Factor 1, alpha Subunit, Molecular biology, Cell Hypoxia, Enzyme Activation, Histone Deacetylase Inhibitors, Oncology, chemistry, Apoptosis, Drug Resistance, Neoplasm, Cancer research, lipids (amino acids, peptides, and proteins), medicine.drug, BH3 Interacting Domain Death Agonist Protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44523974583b7144b9d328441cdeb795
http://europepmc.org/articles/PMC3583540

المؤلفون: Tomas Eckschlager, Pavel Prochazka, Jana Hřebačková, Jan Hraběta, Marie Stiborová, Jitka Poljaková, Svatopluk Smutný

المصدر: Interdisciplinary Toxicology

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, CYP1B1, Pharmacology, histone deacetylase inhibitors, Toxicology, trichostatin A, neuroblastoma, Neuroblastoma, medicine, Cytotoxicity, neoplasms, biology, CYP3A4, Cytochrome P450, medicine.disease, Trichostatin A, Cell culture, biology.protein, Cancer research, valproate, cytotoxicity, lipids (amino acids, peptides, and proteins), Original Article, Histone deacetylase, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c72fc4a21f20844526358f9f7140724
http://europepmc.org/articles/PMC2984103

المؤلفون: Marie Stiborová, Eva Frei, Jan Hraběta, Jana Hřebačková, Tomas Eckschlager, Svatopluk Smutný, René Kizek, Václav Martínek, Jitka Poljaková

المصدر: Biochemical Pharmacology. 77:1466-1479

مصطلحات موضوعية: Cell Survival, Antineoplastic Agents, Apoptosis, Biochemistry, DNA Adducts, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Cell Line, Tumor, DNA adduct, medicine, Humans, Ellipticines, Chromatography, High Pressure Liquid, Peroxidase, Pharmacology, Dose-Response Relationship, Drug, biology, Cell growth, Topoisomerase, Cell Cycle, DNA replication, Molecular biology, chemistry, Mechanism of action, Cyclooxygenase 2, Cell culture, Cyclooxygenase 1, biology.protein, DNA fragmentation, medicine.symptom, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6b665fea7dd9c8a7408d0376d95a5a
https://doi.org/10.1016/j.bcp.2009.01.021