المؤلفون: Markus T. Sainio, Tiina Rasila, Svetlana M. Molchanova, Julius Järvilehto, Rubén Torregrosa-Muñumer, Sandra Harjuhaahto, Jana Pennonen, Nadine Huber, Sanna-Kaisa Herukka, Annakaisa Haapasalo, Henrik Zetterberg, Tomi Taira, Johanna Palmio, Emil Ylikallio, Henna Tyynismaa

المصدر: Frontiers in Cell and Developmental Biology, Vol 9 (2022)

مصطلحات موضوعية: neurofilament light (NfL), motor neurodegeneration, axon, Charcot-Marie-Tooth (CMT) disease, induced pluripotent stem cells, motor neuron (MN), Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.820105/full; https://doaj.org/toc/2296-634X

URL الوصول: https://doaj.org/article/f4541e595e534acebc0b20319f10d18f

المؤلفون: Sandra Harjuhaahto, Tiina S. Rasila, Svetlana M. Molchanova, Rosa Woldegebriel, Jouni Kvist, Svetlana Konovalova, Markus T. Sainio, Jana Pennonen, Rubén Torregrosa-Muñumer, Hazem Ibrahim, Timo Otonkoski, Tomi Taira, Emil Ylikallio, Henna Tyynismaa

المصدر: Neurobiology of Disease, Vol 141, Iss , Pp 104940- (2020)

مصطلحات موضوعية: CHCHD2, CHCHD10, Induced pluripotent stem cell, Motor neuron differentiation, CMT2, SMAJ, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996120302151; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/7dd3bc2f74c846f5b352a344121de51b

المؤلفون: Jeremi J Turkia, Jouni Kvist, Nadine Huber, Ras Trokovic, Vivek Sharma, Markus T. Sainio, Annakaisa Haapasalo, Jana Pennonen, Henna Tyynismaa, Emil Ylikallio, Sanna-Kaisa Herukka, Mari Auranen, Erika Rannila, Marco Reidelbach, Rubén Torregrosa-Muñumer, Sebastian Kenvin

المساهمون: STEMM - Stem Cells and Metabolism Research Program, Department of Physics, Centre of Excellence in Stem Cell Metabolism, Medicum, HUS Neurocenter, Clinicum, Neurologian yksikkö, Research Programs Unit, Institute of Biotechnology, Materials Physics, Helsinki Institute of Life Science HiLIFE, Department of Medical and Clinical Genetics, Henna Tyynismaa / Principal Investigator, Neuroscience Center

مصطلحات موضوعية: Mitochondrial DNA, Protein subunit, Mutant, dna, medicine.disease_cause, DNA, Mitochondrial, 03 medical and health sciences, Adenosine Triphosphate, 0302 clinical medicine, Genetics, medicine, Humans, motor neurons, heteroplasmy, Molecular Biology, Genetics (clinical), 030304 developmental biology, 0303 health sciences, Mutation, biology, ATP synthase, Neurogenesis, General Medicine, Mitochondrial Proton-Translocating ATPases, mitochondrial, Heteroplasmy, Cell biology, MT-ATP6, biology.protein, Ataxia, 3111 Biomedicine, mutation, lactates, metabolism, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f50f541aa9661cc3bf7d89a952c14d
http://hdl.handle.net/10138/345126

المؤلفون: Markus T, Sainio, Tiina, Rasila, Svetlana M, Molchanova, Julius, Järvilehto, Rubén, Torregrosa-Muñumer, Sandra, Harjuhaahto, Jana, Pennonen, Nadine, Huber, Sanna-Kaisa, Herukka, Annakaisa, Haapasalo, Henrik, Zetterberg, Tomi, Taira, Johanna, Palmio, Emil, Ylikallio, Henna, Tyynismaa

المصدر: Frontiers in cell and developmental biology. 9

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::4e467564e71bf755d01fe6739005a578
https://pubmed.ncbi.nlm.nih.gov/35237613

المؤلفون: Jana Pennonen, Markus T. Sainio, Svetlana M. Molchanova, Sandra Harjuhaahto, Jouni Kvist, Henna Tyynismaa, Tomi Taira, Emil Ylikallio, Hazem Ibrahim, Tiina S Rasila, Timo Otonkoski, Rubén Torregrosa-Muñumer, Svetlana Konovalova, Rosa Woldegebriel

المساهمون: Research Programs Unit, STEMM - Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, Centre of Excellence in Stem Cell Metabolism, Henna Tyynismaa / Principal Investigator, Helsinki One Health (HOH), HUS Children and Adolescents, Timo Pyry Juhani Otonkoski / Principal Investigator, Synaptic Plasticity and Neuronal Synchronization, Veterinary Biosciences, Tomi Taira / Principal Investigator, Neuroscience Center, Clinicum, HUS Neurocenter, Department of Neurosciences, Neurologian yksikkö, Helsinki University Hospital Area, Department of Medical and Clinical Genetics, Staff Services, Helsinki Institute of Life Science HiLIFE, Basal ganglia circuits

المصدر: Neurobiology of Disease, Vol 141, Iss, Pp 104940-(2020)

مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, POTENTIATION, ENERGY-METABOLISM, Mitochondrion, AMYOTROPHIC-LATERAL-SCLEROSIS, 3124 Neurology and psychiatry, Membrane Potentials, GLUTAMATE, 0302 clinical medicine, Amyotrophic lateral sclerosis, Induced pluripotent stem cell, Motor Neurons, CMT2, Glutamate receptor, Long-term potentiation, Cell Differentiation, Parkinson Disease, RNA sequencing, Mitochondria, DNA-Binding Proteins, RECEPTORS, medicine.anatomical_structure, Neurology, PLURIPOTENT STEM-CELLS, CHCHD2, Induced Pluripotent Stem Cells, DPP6, Biology, lcsh:RC321-571, Mitochondrial Proteins, 03 medical and health sciences, medicine, Humans, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, CRISPR/Cas9, RELEASE, MUTATIONS, Amyotrophic Lateral Sclerosis, Motor neuron differentiation, 3112 Neurosciences, Spinal muscular atrophy, Motor neuron, medicine.disease, 030104 developmental biology, CHCHD10, SMAJ, Synapses, ALS, Transcriptome, Neuroscience, 030217 neurology & neurosurgery, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191057f2ef982386dd6e451124a5528c
http://hdl.handle.net/10138/317778

المؤلفون: Sandra Harjuhaahto, Henna Tyynismaa, Jana Pennonen, Tomi Taira, Hazem Ibrahim, Markus T. Sainio, Svetlana M. Molchanova, Emil Ylikallio, Tiina S Rasila, Jouni Kvist, Timo Otonkoski, Svetlana Konovalova, Rosa Woldegebriel

مصطلحات موضوعية: 0303 health sciences, Mitochondrial intermembrane space, Spinal muscular atrophy, Motor neuron, Biology, medicine.disease, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Gene expression, medicine, Amyotrophic lateral sclerosis, Gene, Neuroscience, 030217 neurology & neurosurgery, Function (biology), 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb243d187a42916be1085a7bf5882bf1