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المؤلفون: Christine Humblet, Jeremy E. Edmunds, and M. Arshad Siddiqui, ‡ Yves St-Denis, Debra R. Holland, Janet S. Plummer, Lakshmi S. Narasimhan, Stephen T. Rapundalo, J. Ronald Rubin
المصدر: Journal of Medicinal Chemistry. 43:361-368
مصطلحات موضوعية: Models, Molecular, Arginine, Peptidomimetic, Stereochemistry, Amidines, Molecular Conformation, Chymotrypsinogen, Crystallography, X-Ray, Ligands, Structure-Activity Relationship, Thrombin, Drug Discovery, medicine, chemistry.chemical_classification, Alanine, biology, Chemistry, Molecular Mimicry, Trypsin, Enzyme, Enzyme inhibitor, biology.protein, Molecular Medicine, Trypsin Inhibitors, Factor Xa Inhibitors, medicine.drug, Discovery and development of direct thrombin inhibitors
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المؤلفون: Walter Michael, Cuiman Cai, M. Desiree Watson, Lori M. Evans, Kevin K.W. Wang, Mark R. Emmerling, John L. Gilmore, Sheryl J. Hays, Lakshmi S. Narasimhan, Juan C. Jaen, Janet S. Plummer, Rathna Nath
المصدر: Bioorganic & Medicinal Chemistry Letters. 9:815-820
مصطلحات موضوعية: Erythrocytes, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Complement C1 Inactivator Proteins, Biochemistry, Inhibitory Concentration 50, Drug Discovery, medicine, Animals, Complement C1r, Molecular Biology, Serine protease, Sulfonamides, Sheep, Protease, biology, Chemistry, Organic Chemistry, medicine.disease, Trypsin, Hemolysis, In vitro, Kinetics, Models, Chemical, biology.protein, Molecular Medicine, Functional activity, medicine.drug
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المؤلفون: A. Susser, Peter D. Winocour, John DiMaio, Debra R. Holland, M. Arshad Siddiqui, Kent A. Berryman, Sophie Levesque, Janet S. Plummer, D. Lafleur, Jeremy J. Edmunds, Scott R. Eaton, J. Ronald Rubin, Annette Marian Doherty, Cuiman Cai, Wayne L. Cody, Stephen T. Rapundalo, Lakshmi S. Narasimhan, Yves St-Denis
المصدر: Bioorganic & Medicinal Chemistry Letters. 9:835-840
مصطلحات موضوعية: Models, Molecular, Lactams, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Inhibitory Concentration 50, chemistry.chemical_compound, Thrombin, Heterocyclic Compounds, Drug Discovery, Antithrombotic, medicine, Animals, Molecular Biology, biology, Bicyclic molecule, Chemistry, Organic Chemistry, Active site, Thrombosis, Rats, Disease Models, Animal, Kinetics, Models, Chemical, Enzyme inhibitor, biology.protein, Lactam, Molecular Medicine, medicine.drug, Discovery and development of direct thrombin inhibitors
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المؤلفون: J. Ronald Rubin, Darin R. Kent, Debra R. Holland, John DiMaio, Yves St-Denis, Annette Marian Doherty, Sophie Levesque, Cuiman Cai, Peter D. Winocour, Jeremy J. Edmunds, M. Arshad Siddiqui, Lakshmi S. Narasimhan, Stephen T. Rapundalo, Janet S. Plummer, John X. He, Alan J. Susser, Kent A. Berryman, Wayne L. Cody
المصدر: Bioorganic & Medicinal Chemistry Letters. 8:3409-3414
مصطلحات موضوعية: Serine Proteinase Inhibitors, Lactams, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Thrombin, Fibrinolytic Agents, Drug Discovery, Antithrombotic, medicine, Animals, Structure–activity relationship, Molecular Biology, biology, Bicyclic molecule, Chemistry, Organic Chemistry, Rats, Enzyme inhibitor, biology.protein, Lactam, Molecular Medicine, medicine.drug, Discovery and development of direct thrombin inhibitors
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المصدر: e-EROS Encyclopedia of Reagents for Organic Synthesis
مصطلحات موضوعية: Inorganic chemistry, chemistry.chemical_element, Toluene, Chloride, Ruthenium, chemistry.chemical_compound, chemistry, Dichlorotris(triphenylphosphine)ruthenium(II), Polymer chemistry, Nitro, medicine, Triphenylphosphine, Solubility, Benzene, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7661147f243dc1cd5cf5305f2d842c06
https://doi.org/10.1002/047084289x.rd137.pub3 -
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المؤلفون: Mark J. Suto, Michael Andrew Stier, Janet S. Plummer, Lori A. Emery
المصدر: Tetrahedron Letters. 34:7529-7532
مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, chemistry, Nitromethane, education, Organic Chemistry, Drug Discovery, Michael reaction, Organic chemistry, Stereoselectivity, Biochemistry, humanities, Amino acid
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المؤلفون: Minn-Chang Cheng, Tian-Pa You, Yan Wang, Ki-Bum Kim, Yi-Tsong Lin, Harry S. Mosher, Jamil Talhouk, Janet S. Plummer
المصدر: ChemInform. 22
مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, chemistry, Stereochemistry, Nitro, Diastereomer, General Medicine, Uronic acid, Furanose, Protecting group, Sequence (medicine)
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المؤلفون: Janet S. Plummer, Takashi Yamazaki, John T. Welch, Rayomand H Gimi
المصدر: ChemInform. 23
مصطلحات موضوعية: Claisen rearrangement, Crotyl, chemistry.chemical_compound, Chiral auxiliary, chemistry, Stereochemistry, Amide, Acetal, Enantioselective synthesis, Ketene, General Medicine, Fluoroacetamide
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المؤلفون: A L A L Et Et, Janet S. Plummer
المصدر: ChemInform. 30
مصطلحات موضوعية: chemistry.chemical_compound, Thrombin, Bicyclic molecule, chemistry, Stereochemistry, medicine, Lactam, General Medicine, medicine.drug
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المؤلفون: Janet S. Plummer, et al. et al.
المصدر: ChemInform. 30
مصطلحات موضوعية: chemistry.chemical_compound, Thrombin, Bicyclic molecule, Stereochemistry, Chemistry, medicine, Lactam, General Medicine, medicine.drug