المؤلفون: Wechalekar, A, Antoni, G, Al Azzam, W, Bergström, M, Biswas, S, Chen, C, Cheriyan, J, Cleveland, M, Cookson, L, Galette, P, Janiczek, RL, Kwong, RY, Lukas, MA, Millns, H, Richards, D, Schneider, I, Solomon, SD, Sörensen, J, Storey, J, Thompson, D, van Dongen, G, Vugts, DJ, Wall, A, Wikström, G, Falk, RH

المساهمون: Wechalekar, Ashutosh [0000-0002-4406-7237], Apollo - University of Cambridge Repository, Cheriyan, Joseph [0000-0001-6921-1592], Radiology and nuclear medicine, CCA - Cancer Treatment and quality of life, CCA - Imaging and biomarkers, AII - Inflammatory diseases

المصدر: Wechalekar, A, Antoni, G, Al Azzam, W, Bergström, M, Biswas, S, Chen, C, Cheriyan, J, Cleveland, M, Cookson, L, Galette, P, Janiczek, R L, Kwong, R Y, Lukas, M A, Millns, H, Richards, D, Schneider, I, Solomon, S D, Sörensen, J, Storey, J, Thompson, D, van Dongen, G, Vugts, D J, Wall, A, Wikström, G & Falk, R H 2022, ' Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis : an open-label Phase 2 study and an adjunctive immuno-PET imaging study ', BMC Cardiovascular Disorders, vol. 22, no. 1, 49 . https://doi.org/10.1186/s12872-021-02407-6
BMC Cardiovascular Disorders, 22(1). BioMed Central
BMC Cardiovascular Disorders, 22(1):49. BioMed Central

مصطلحات موضوعية: Male, Positron emission tomography, Pyrrolidines, Time Factors, Structural Diseases, Heart Failure & Congenital, Carboxylic Acids, Cardiac amyloidosis, Serum amyloid P component, Miridesap, Ventricular Function, Left, Predictive Value of Tests, Humans, Cardiac and Cardiovascular Systems, Aged, Aged, 80 and over, Kardiologi, Systemic amyloidosis, Ventricular Remodeling, Myocardium, Dezamizumab, Antibodies, Monoclonal, Amyloidosis, Magnetic Resonance Imaging, United Kingdom, United States, Serum Amyloid P-Component, Treatment Outcome, Positron-Emission Tomography, Immuno-PET, Female, Drug Therapy, Combination, Radiologi och bildbehandling, Cardiomyopathies, Cardiology and Cardiovascular Medicine, Radiology, Nuclear Medicine and Medical Imaging, Research Article

وصف الملف: application/pdf; application/zip; text/xml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d43a27d4681e51d8685ea3c4e47388
https://doi.org/10.1186/s12872-021-02407-6

المؤلفون: Murphy PS; Janssen Research and Development, High Wycombe, Buckinghamshire, United Kingdom., Galette P; Telix Pharmaceuticals (US) Inc, Fishers, United States., van der Aart J; GSK Research and Development, Hertfordshire, United Kingdom., Janiczek RL; Janssen Research and Development, Spring House, United States., Patel N; Telix Pharmaceuticals (US) Inc, Fishers, United States.; Department of Radiology, Churchill Hospital, Oxford University NHS Foundation Trust, Oxford, United Kingdom., Brown AP; Vale Imaging Consultancy Solutions, Harston, Cambridge, United Kingdom.

المصدر: The British journal of radiology [Br J Radiol] 2023 Oct; Vol. 96 (1150), pp. 20211126. Date of Electronic Publication: 2023 Aug 15.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0373125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1748-880X (Electronic) Linking ISSN: 00071285 NLM ISO Abbreviation: Br J Radiol Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/diagnostic imaging , Neoplasms*/drug therapy, Humans ; Magnetic Resonance Imaging ; Positron-Emission Tomography

المؤلفون: Cheriyan J; Research, GSK Clinical Unit Cambridge, Cambridge, UK.; Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK.; Cardiovascular Clinical Trials Office, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Roberts A; Clinical Imaging, GSK, Stevenage, UK., Roberts C; Imaging Services, Bioxydyn Ltd, Manchester, UK., Graves MJ; Cardiovascular Clinical Trials Office, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Radiology, University of Cambridge, Cambridge, UK., Patterson I; Cardiovascular Clinical Trials Office, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Slough RA; Cardiovascular Clinical Trials Office, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Schroyer R; Statistics, GSK, Collegeville, Pennsylvania, USA., Fernando D; Research, GSK Clinical Unit Cambridge, Cambridge, UK., Kumar S; Research, GSK Clinical Unit Cambridge, Cambridge, UK., Lee S; Consulting, Amallis Consulting Ltd, London, UK., Parker GJM; Imaging Services, Bioxydyn Ltd, Manchester, UK.; Centre for Medical Imaging Computing, Department of Computer Science, University College London, London, UK., Sarov-Blat L; Research and Development, GSK, Crescent Drive, Philadelphia, Pennsylvania, USA., McEniery C; Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK., Middlemiss J; Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK., Sprecher D; Consulting, BioView Consulting LLC, Blue Bell, Pennsylvania, USA., Janiczek RL; Clinical Imaging, GSK, Stevenage, UK.

المصدر: Journal of magnetic resonance imaging : JMRI [J Magn Reson Imaging] 2022 Aug; Vol. 56 (2), pp. 450-461. Date of Electronic Publication: 2022 Mar 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9105850 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-2586 (Electronic) Linking ISSN: 10531807 NLM ISO Abbreviation: J Magn Reson Imaging Subsets: MEDLINE

مواضيع طبية MeSH: Contrast Media* , Heart Failure*/diagnostic imaging, Humans ; Lung/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Permeability

المؤلفون: MacKay JW; Department of Radiology, University of Cambridge, Cambridge, UK. james.w.mackay@uea.ac.uk.; Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UY, UK. james.w.mackay@uea.ac.uk., Nezhad FS; Bioxydyn Limited, Manchester, UK., Rifai T; Department of Radiology, Norfolk & Norwich University Hospital, Norwich, UK., Kaggie JD; Department of Radiology, University of Cambridge, Cambridge, UK., Naish JH; Bioxydyn Limited, Manchester, UK., Roberts C; Bioxydyn Limited, Manchester, UK., Graves MJ; Department of Radiology, University of Cambridge, Cambridge, UK., Waterton JC; Bioxydyn Limited, Manchester, UK.; Centre for Imaging Sciences, Division of Informatics Imaging & Data Sciences, School of Health Sciences, Faculty of Biology Medicine & Health, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK., Janiczek RL; Clinical Imaging, GlaxoSmithKline, London, UK., Roberts AR; Clinical Imaging, GlaxoSmithKline, London, UK.; Antaros Medical, Uppsala, Sweden., McCaskie A; Division of Trauma & Orthopaedics, Department of Surgery, University of Cambridge, Cambridge, UK., Gilbert FJ; Department of Radiology, University of Cambridge, Cambridge, UK., Parker GJM; Bioxydyn Limited, Manchester, UK.; Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London, UK.

المصدر: European radiology [Eur Radiol] 2021 Aug; Vol. 31 (8), pp. 5746-5758. Date of Electronic Publication: 2021 Feb 16.

نوع المنشور: Journal Article; Observational Study

بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 9114774 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1084 (Electronic) Linking ISSN: 09387994 NLM ISO Abbreviation: Eur Radiol Subsets: MEDLINE

مواضيع طبية MeSH: Osteoarthritis, Knee*/diagnostic imaging , Synovitis*/diagnostic imaging, Contrast Media ; Humans ; Infant ; Knee Joint ; Magnetic Resonance Imaging ; Prospective Studies

المؤلفون: Kessler DA; Department of Radiology, University of Cambridge, UK., MacKay JW; Department of Radiology, University of Cambridge, UK.; Norwich Medical School, University of East Anglia, Norwich, UK., McDonald S; Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK., McDonnell S; Division of Trauma and Orthopaedics, Department of Surgery, University of Cambridge, Cambridge, UK., Grainger AJ; Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK., Roberts AR; Antaros Medical, Uppsala, Sweden., Janiczek RL; Clinical Imaging, GlaxoSmithKline, London, UK., Graves MJ; Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK., Kaggie JD; Department of Radiology, University of Cambridge, UK., Gilbert FJ; Department of Radiology, University of Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK.

المصدر: Journal of magnetic resonance imaging : JMRI [J Magn Reson Imaging] 2020 Dec; Vol. 52 (6), pp. 1753-1764. Date of Electronic Publication: 2020 Jul 16.

نوع المنشور: Journal Article; Observational Study; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9105850 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-2586 (Electronic) Linking ISSN: 10531807 NLM ISO Abbreviation: J Magn Reson Imaging Subsets: MEDLINE

مواضيع طبية MeSH: Cartilage, Articular*/diagnostic imaging, Humans ; Knee ; Knee Joint/diagnostic imaging ; Magnetic Resonance Imaging ; Tibia/diagnostic imaging

المؤلفون: Spath NB; BHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, EH16 4SA, UK.; Edinburgh Heart Centre, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK.; Edinburgh Imaging, University of Edinburgh, Edinburgh, EH16 4TJ, UK., Singh T; BHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, EH16 4SA, UK.; Edinburgh Heart Centre, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK.; Edinburgh Imaging, University of Edinburgh, Edinburgh, EH16 4TJ, UK., Papanastasiou G; BHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, EH16 4SA, UK.; Edinburgh Imaging, University of Edinburgh, Edinburgh, EH16 4TJ, UK., Kershaw L; Edinburgh Imaging, University of Edinburgh, Edinburgh, EH16 4TJ, UK.; Centre for Inflammation Research, University of Edinburgh, Edinburgh, EH16 4TJ, UK., Baker AH; BHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, EH16 4SA, UK., Janiczek RL; Department of Clinical Imaging, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Gulsin GS; Department of Cardiovascular Sciences, University of Leicester, NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, LE3 9QP, UK., Dweck MR; BHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, EH16 4SA, UK.; Edinburgh Heart Centre, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK.; Edinburgh Imaging, University of Edinburgh, Edinburgh, EH16 4TJ, UK., McCann G; Department of Cardiovascular Sciences, University of Leicester, NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, LE3 9QP, UK., Newby DE; BHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, EH16 4SA, UK.; Edinburgh Heart Centre, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK.; Edinburgh Imaging, University of Edinburgh, Edinburgh, EH16 4TJ, UK., Semple SI; BHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, EH16 4SA, UK.; Edinburgh Imaging, University of Edinburgh, Edinburgh, EH16 4TJ, UK.

المصدر: European heart journal. Cardiovascular Imaging [Eur Heart J Cardiovasc Imaging] 2020 Nov 17. Date of Electronic Publication: 2020 Nov 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101573788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-2412 (Electronic) Linking ISSN: 20472404 NLM ISO Abbreviation: Eur Heart J Cardiovasc Imaging Subsets: MEDLINE

المؤلفون: MacKay JW; Department of Radiology, University of Cambridge, Cambridge, UK.; Norwich Medical School, University of East Anglia, Norwich, UK., Kaggie JD; Department of Radiology, University of Cambridge, Cambridge, UK., Treece GM; Department of Engineering, University of Cambridge, Cambridge, UK., McDonnell SM; Division of Trauma & Orthopaedics, Department of Surgery, University of Cambridge, Cambridge, UK., Khan W; Division of Trauma & Orthopaedics, Department of Surgery, University of Cambridge, Cambridge, UK., Roberts AR; Clinical Imaging, GlaxoSmithKline, London, UK.; Antaros Medical, Uppsala, Sweden., Janiczek RL; Clinical Imaging, GlaxoSmithKline, London, UK., Graves MJ; Department of Radiology, University of Cambridge, Cambridge, UK., Turmezei TD; Norwich Medical School, University of East Anglia, Norwich, UK.; Department of Radiology, Norfolk & Norwich University Hospital, Norwich, UK., McCaskie AW; Division of Trauma & Orthopaedics, Department of Surgery, University of Cambridge, Cambridge, UK., Gilbert FJ; Department of Radiology, University of Cambridge, Cambridge, UK.

المصدر: Journal of magnetic resonance imaging : JMRI [J Magn Reson Imaging] 2020 Oct; Vol. 52 (4), pp. 1139-1151. Date of Electronic Publication: 2020 May 24.

نوع المنشور: Journal Article; Observational Study; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9105850 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-2586 (Electronic) Linking ISSN: 10531807 NLM ISO Abbreviation: J Magn Reson Imaging Subsets: MEDLINE

مواضيع طبية MeSH: Cartilage, Articular*/diagnostic imaging , Osteoarthritis, Knee*/diagnostic imaging, Adult ; Gadolinium DTPA ; Humans ; Infant ; Knee Joint ; Magnetic Resonance Imaging ; Middle Aged ; Reproducibility of Results

المؤلفون: de Groot M; Clinical Pharmacology and Experimental Medicine, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, UK.; Department of Radiology, University of Cambridge, Cambridge, UK., Patel N; Clinical Pharmacology and Experimental Medicine, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, UK., Manavaki R; Department of Radiology, University of Cambridge, Cambridge, UK., Janiczek RL; Clinical Pharmacology and Experimental Medicine, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, UK., Bergstrom M; Clinical Pharmacology and Experimental Medicine, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, UK., Östör A; Monash University, Cabrini Medical Centre, Melbourne, Australia., Gerlag D; RxCelerate, Cambridge, UK., Roberts A; Clinical Pharmacology and Experimental Medicine, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, UK., Graves MJ; Department of Radiology, University of Cambridge, Cambridge, UK., Karkera Y; Biostatistics, GlaxoSmithKline R&D, Bangalore, India., Fernando D; Clinical Unit Cambridge (CUC), GlaxoSmithKline R&D, Addenbrooke's Hospital, Cambridge, UK., Mistry P; Biostatistics, GlaxoSmithKline R&D, Bangalore, India., Walker A; Clinical Unit Cambridge (CUC), GlaxoSmithKline R&D, Addenbrooke's Hospital, Cambridge, UK., Wisniacki N; Clinical Pharmacology and Experimental Medicine, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, UK., Fryer TD; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Jimenez-Royo P; Clinical Pharmacology and Experimental Medicine, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, UK. Pilar.x.Jimenex-Royo@gsk.com.

المصدر: EJNMMI research [EJNMMI Res] 2019 Dec 19; Vol. 9 (1), pp. 113. Date of Electronic Publication: 2019 Dec 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Berlin Country of Publication: Germany NLM ID: 101560946 Publication Model: Electronic Cited Medium: Print ISSN: 2191-219X (Print) Linking ISSN: 2191219X NLM ISO Abbreviation: EJNMMI Res Subsets: PubMed not MEDLINE

المؤلفون: Spath NB; British Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, UK., Lilburn DML; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK., Gray GA; British Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, UK., Le Page LM; British Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, UK., Papanastasiou G; British Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, UK., Lennen RJ; British Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, UK.; Edinburgh Preclinical Imaging, University of Edinburgh, Edinburgh, UK., Janiczek RL; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, UK., Dweck MR; British Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, UK.; Department of Cardiology, Royal Infirmary of Edinburgh, Edinburgh, UK., Newby DE; British Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, UK.; Department of Cardiology, Royal Infirmary of Edinburgh, Edinburgh, UK., Yang PC; Department of Cardiology, Stanford University, Stanford, CA, USA., Jansen MA; British Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, UK.; Edinburgh Preclinical Imaging, University of Edinburgh, Edinburgh, UK., Semple SI; British Heart Foundation Centre of Cardiovascular Science, University of Edinburgh, Edinburgh, UK.

المصدر: Contrast media & molecular imaging [Contrast Media Mol Imaging] 2018 Oct 25; Vol. 2018, pp. 9641527. Date of Electronic Publication: 2018 Oct 25 (Print Publication: 2018).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Hindawi in collaboration with John Wiley & Sons, Inc Country of Publication: England NLM ID: 101286760 Publication Model: eCollection Cited Medium: Internet ISSN: 1555-4317 (Electronic) Linking ISSN: 15554309 NLM ISO Abbreviation: Contrast Media Mol Imaging

مواضيع طبية MeSH: Coronary Vessels*/diagnostic imaging , Coronary Vessels*/metabolism , Magnetic Resonance Imaging* , Myocardial Infarction*/diagnostic imaging , Myocardial Infarction*/metabolism, Contrast Media/*pharmacology , Manganese/*pharmacology , Myocardium/*metabolism, Animals ; Male ; Rats ; Rats, Sprague-Dawley

المؤلفون: Hoy AM; MRC/University of Edinburgh Centre for Inflammation Research, Edinburgh EH16 4TJ, UK., McDonald N; MRC/University of Edinburgh Centre for Inflammation Research, Edinburgh EH16 4TJ, UK., Lennen RJ; BHF/University of Edinburgh Centre for Cardiovascular Science, Edinburgh EH16 4TJ, UK.; Edinburgh Preclinical Imaging (EPI), University of Edinburgh, Edinburgh EH16 4TJ, UK., Milanesi M; Perspectum Diagnostics, Oxford OX1 2ET, UK., Herlihy AH; Perspectum Diagnostics, Oxford OX1 2ET, UK., Kendall TJ; MRC/University of Edinburgh Centre for Inflammation Research, Edinburgh EH16 4TJ, UK.; Division of Pathology, University of Edinburgh, Edinburgh EH16 4SA, UK., Mungall W; Biomedical Research Resources, University of Edinburgh, Edinburgh EH16 4SB, UK., Gyngell M; Perspectum Diagnostics, Oxford OX1 2ET, UK., Banerjee R; Perspectum Diagnostics, Oxford OX1 2ET, UK., Janiczek RL; GlaxoSmithKline (Experimental Medicine Imaging), Stevenage SG1 2NY, UK., Murphy PS; GlaxoSmithKline (Experimental Medicine Imaging), Stevenage SG1 2NY, UK., Jansen MA; BHF/University of Edinburgh Centre for Cardiovascular Science, Edinburgh EH16 4TJ, UK.; Edinburgh Preclinical Imaging (EPI), University of Edinburgh, Edinburgh EH16 4TJ, UK., Fallowfield JA; MRC/University of Edinburgh Centre for Inflammation Research, Edinburgh EH16 4TJ, UK Jonathan.Fallowfield@ed.ac.uk.

المصدر: Biology open [Biol Open] 2018 Jul 02; Vol. 7 (7). Date of Electronic Publication: 2018 Jul 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101578018 Publication Model: Electronic Cited Medium: Print ISSN: 2046-6390 (Print) Linking ISSN: 20466390 NLM ISO Abbreviation: Biol Open Subsets: PubMed not MEDLINE