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1دورية أكاديمية
المؤلفون: Björn Heinrichs, Baowen Liu, Jin Zhang, Jannis E. Meents, Kim Le, Andelain Erickson, Petra Hautvast, Xiwen Zhu, Ningbo Li, Yi Liu, Marc Spehr, Ute Habel, Markus Rothermel, Barbara Namer, Xianwei Zhang, Angelika Lampert, Guangyou Duan
المصدر: Frontiers in Molecular Neuroscience, Vol 14 (2021)
مصطلحات موضوعية: SCN10A/Nav1.8, autism spectrum disorder, p.I1511M, p.R512∗, genetic, mutation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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المؤلفون: Angelika Lampert, Jannis E. Meents, Andelain Erickson, Markus Rothermel, Corinna Rösseler, Stephan von Hörsten, Sebastian Giesselmann, Bernd Denecke, Geraldine Zimmer-Bensch, Ingo Kurth, Daniel Pensold, Virginia B. Mattis, Petra Hautvast, Kim Le Cann, Tim Clarner, Alec Foerster
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific reports 11, 6934 (2021). doi:10.1038/s41598-021-85656-xمصطلحات موضوعية: Science, Cell, Induced Pluripotent Stem Cells, Cell Culture Techniques, Action Potentials, Neuropathology, Biology, medicine.disease_cause, Medium spiny neuron, Molecular neuroscience, Ion channels in the nervous system, Article, Cell Line, Huntington's disease, medicine, Animals, Humans, Induced pluripotent stem cell, Stem cells in the nervous system, gamma-Aminobutyric Acid, Neurons, Mutation, Multidisciplinary, Voltage-Gated Sodium Channel beta-4 Subunit, Cell Differentiation, medicine.disease, In vitro, Cellular neuroscience, Mice, Inbred C57BL, medicine.anatomical_structure, Huntington Disease, nervous system, Case-Control Studies, Medicine, Calcium, ddc:600, Neuroscience, Immunostaining
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المؤلفون: Andelain Erickson, Maike F. Dohrn, Markus Rothermel, Kim Le Cann, Ingo Kurth, Petra Hautvast, Martin Bialer, Andrea B. Maier, Jannis E. Meents, Jannis Körner, Roman Rolke, Vishal Sudha Bhagavath Eswaran, Angelika Lampert, Raya A. Bott
المصدر: Channels 15(1), 208-228 (2021). doi:10.1080/19336950.2020.1870087
Channels
article-version (VoR) Version of Recordمصطلحات موضوعية: 0301 basic medicine, Patch-Clamp Techniques, homology modeling, Biophysics, Context (language use), Bioinformatics, Biochemistry, patch-clamp recordings, Membrane Potentials, orthostatic hypotension, 03 medical and health sciences, Orthostatic vital signs, 0302 clinical medicine, Erythromelalgia, ddc:570, Medicine, Humans, pain, hek293t cells, Gene, inherited pain, business.industry, Sodium channel, nav1.7 mutation, HEK 293 cells, NAV1.7 Voltage-Gated Sodium Channel, medicine.disease, 030104 developmental biology, HEK293 Cells, NAV1, Primary Erythromelalgia, business, 030217 neurology & neurosurgery, Research Article, Research Paper, sodium channel
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المؤلفون: Tobias Huth, Stefanie Bothe, Jannis E. Meents, Sarah Thull, Ralf Hausmann, Andrias O. O'Reilly, Angelika Lampert, Cristian Neacsu
المصدر: Data in Brief
Data in Brief 31, 105844 (2020). doi:10.1016/j.dib.2020.105844
Data in Brief, Vol 31, Iss, Pp 105844-(2020)مصطلحات موضوعية: β4-peptide, ATx-II, Peptide, Gating, Nav1.5, lcsh:Computer applications to medicine. Medical informatics, Sodium channel gating states, QH301, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Persistent current, ddc:570, Voltage-gated sodium channel, Patch clamp, lcsh:Science (General), 030304 developmental biology, chemistry.chemical_classification, Human Nav1.5, 0303 health sciences, Multidisciplinary, biology, Sodium channel, Nav channel, Pharmacology, Toxicology and Pharmaceutical Science, Electrophysiology, Deltamethrin, chemistry, Resurgent current, biology.protein, Biophysics, lcsh:R858-859.7, 030217 neurology & neurosurgery, lcsh:Q1-390
وصف الملف: application/pdf
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المصدر: J Biol Chem
The Journal of Biological Chemistry
The journal of biological chemistry : JBC 296, 100227 (2020). doi:10.1074/jbc.RA120.014288مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Conformation, alpha-Helical, Threonine, Patch-Clamp Techniques, Gene Expression, HEK, human embryonic kidney cell line, Gating, medicine.disease_cause, Erev, reversal potential, Biochemistry, Membrane Potentials, pain, Phosphorylation, Nav1.7, Protein Kinase C, Mutation, Kinase, Chemistry, protein kinase C (PKC), NAV1.7 Voltage-Gated Sodium Channel, Erythromelalgia, Recombinant Proteins, Cell biology, protein kinase A (PKA), k, slope factor, V1/2, membrane potential at half-maximal activation/inactivation, CHO-K1, Chinese hamster ovary cell line, Additions and Corrections, Chronic Pain, Ion Channel Gating, Research Article, sodium channel, Protein Binding, PMA, phorbol 12-myristate 13-acetate, Vm, membrane potential, IEM, inherited erythromelalgia, patch clamp, 03 medical and health sciences, PKC, protein kinase C, medicine, Humans, Protein Interaction Domains and Motifs, Isoleucine, Protein kinase A, Molecular Biology, Protein Kinase Inhibitors, Protein kinase C, Binding Sites, 030102 biochemistry & molecular biology, Nav, voltage-gated sodium channel, Sodium channel, Cell Biology, Diff., difference, medicine.disease, S, staurosporine, Staurosporine, CI, confidence interval, 030104 developmental biology, HEK293 Cells, Amino Acid Substitution, I848T, PKA, protein kinase A, Protein Conformation, beta-Strand, CC, calphostin C, Protein Processing, Post-Translational
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6628d415725194e0eeb9e9987d7a3a
https://pubmed.ncbi.nlm.nih.gov/34481319 -
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المؤلفون: Angelika Lampert, Cristian Neacsu, Andrias O. O'Reilly, Sarah Thull, Ralf Hausmann, Tobias Huth, Jannis E. Meents, Stefanie Bothe
المصدر: Toxicology and applied pharmacology. 397
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, RM, Pyrethroid, biology, Chemistry, Sodium channel, Sodium, chemistry.chemical_element, Gating, Nav1.5, Toxicology, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Deltamethrin, 030220 oncology & carcinogenesis, parasitic diseases, biology.protein, Cellular excitability, Biophysics, Conducting channel
وصف الملف: application/pdf
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المؤلفون: Jannis E. Meents, Carène A. Benasolo, Nikolay Bebrivenski, Christian Neuhof, Guenther Schmalzing, Angelika Lampert, Jannis Körner, Petra Hautvast, Silvia Detro-Dassen, Jan-Philipp Machtens, Annika Ruehlmann, Ralf Hausmann
المصدر: British journal of pharmacology : BJP 177(19), 4481-4496 (2020). doi:10.1111/bph.15196
British journal of pharmacology 177(19), 4481-4496 (2020). doi:10.1111/bph.15196
British Journal of Pharmacologyمصطلحات موضوعية: 0301 basic medicine, channel gating, Mutant, Allosteric regulation, Pain, Gating, 03 medical and health sciences, 0302 clinical medicine, Erythromelalgia, biophysics, Paroxysmal extreme pain disorder, medicine, Humans, ddc:610, Pharmacology, Chemistry, Sodium channel, Mutagenesis, HEK 293 cells, NAV1.7 Voltage-Gated Sodium Channel, medicine.disease, Research Papers, 030104 developmental biology, Phenotype, patch‐clamp, Mutation, Biophysics, molecular simulations, mutagenesis, 030217 neurology & neurosurgery, Research Paper
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المؤلفون: Günther Schmalzing, Silvia Detro-Dassen, Jannis E. Meents, Corinna Rösseler, Ralf Hausmann, Martin Hampl, Luisa Kaluza, Petra Hautvast, Angelika Lampert
المصدر: Pflügers Archiv - European Journal of Physiology. 470:1787-1801
مصطلحات موضوعية: 0301 basic medicine, Lidocaine, Physiology, Xenopus, Clinical Biochemistry, Action Potentials, Gating, Pharmacology, NAV1.8 Voltage-Gated Sodium Channel, 03 medical and health sciences, 0302 clinical medicine, Loss of Function Mutation, Cell Line, Tumor, Physiology (medical), medicine, Animals, Humans, Anesthetics, Local, Receptor, Loss function, business.industry, Sodium channel, Cell Membrane, Chronic pain, medicine.disease, Protein Transport, Electrophysiology, 030104 developmental biology, NAV1, Chronic Pain, business, 030217 neurology & neurosurgery, medicine.drug
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المؤلفون: Krisztina Juhasz, Vera Peuckmann-Post, Angelika Lampert, Sonja Stölzle-Feix, Roman Rolke, Jannis E. Meents
المصدر: British Journal of Pharmacology. 175:3007-3020
مصطلحات موضوعية: 0301 basic medicine, Long QT syndrome, Nav1.5, Pharmacology, Cell Line, NAV1.5 Voltage-Gated Sodium Channel, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Humans, Myocytes, Cardiac, biology, business.industry, Sodium channel, Chronic pain, Sudden cardiac arrest, medicine.disease, Research Papers, Analgesics, Opioid, Electrophysiology, 030104 developmental biology, Opioid, biology.protein, medicine.symptom, business, Oxycodone, 030217 neurology & neurosurgery, Sodium Channel Blockers, medicine.drug
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المصدر: The Journal of Physiology. 596:2433-2445
مصطلحات موضوعية: 0301 basic medicine, Physiology, Chemistry, Protein subunit, Sodium channel, Mutant, Gating, 03 medical and health sciences, 030104 developmental biology, Shear stress, Biophysics, Patch clamp, Ion channel, Intracellular
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