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1
المؤلفون: Yingyao Zhou, Frederick Lo, Steven C. Cook, Zhizhong Li, Bin Zhou, Kaisheng Chen, Jason Chyba, Puiying Annie Mak, Doug Quackenbush, Minhua Qiu, Jason T. Matzen
المصدر: BMC Bioinformatics, Vol 21, Iss 1, Pp 1-13 (2020)
BMC Bioinformaticsمصطلحات موضوعية: Quality Control, Support Vector Machine, Computer science, Image quality, Cells, lcsh:Computer applications to medicine. Medical informatics, 01 natural sciences, Biochemistry, Cell Line, Workflow, 03 medical and health sciences, Structural Biology, Machine learning, CellProfiler, Image Processing, Computer-Assisted, Animals, Humans, Cluster analysis, Molecular Biology, lcsh:QH301-705.5, 030304 developmental biology, 0303 health sciences, Artifact (error), Cell-level quality control, business.industry, Applied Mathematics, Methodology Article, High throughput image analysis, Pattern recognition, Thresholding, 0104 chemical sciences, Computer Science Applications, Staining, Support vector machine, 010404 medicinal & biomolecular chemistry, Phenotype, lcsh:Biology (General), Feature (computer vision), Metric (mathematics), Image quality measurement, lcsh:R858-859.7, Artificial intelligence, business, Artifacts, Algorithms
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2
المؤلفون: Martin D, Brand, Renata L S, Goncalves, Adam L, Orr, Leonardo, Vargas, Akos A, Gerencser, Martin, Borch Jensen, Yves T, Wang, Simon, Melov, Carolina N, Turk, Jason T, Matzen, Victoria J, Dardov, H Michael, Petrassi, Shelly L, Meeusen, Irina V, Perevoshchikova, Heinrich, Jasper, Paul S, Brookes, Edward K, Ainscow
المصدر: Cell metabolism. 24(4)
مصطلحات موضوعية: Caspase 7, Electron Transport Complex I, Hyperplasia, Caspase 3, Stem Cells, Tunicamycin, Heart, Hydrogen Peroxide, Oxidative Phosphorylation, Article, Mitochondria, Muscle, Rats, Intestines, Perfusion, Mice, Oxidative Stress, Cytoprotection, Superoxides, Astrocytes, Reperfusion Injury, Animals, Drosophila, Cells, Cultured, Cell Proliferation
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3
المؤلفون: Jason T. Matzen, Paul A. Anderson, Case W. McNamara, Kelli Kuhen, Nathanael S. Gray, Jeff Janes, Arnab Chatterjee, David Plouffe, Kerstin Henson, Jeremy S. Caldwell, S. Frank Yan, Advait Nagle, Richard E. Trager, Tae-gyu Nam, Elizabeth A. Winzeler, Yingyao Zhou, Nobutaka Kato, Peter G. Schultz, Francisco Adrian, Achim Brinker
المصدر: Proceedings of the National Academy of Sciences. 105:9059-9064
مصطلحات موضوعية: Models, Molecular, Antiparasitic, medicine.drug_class, High-throughput screening, In silico, Plasmodium falciparum, Drug Evaluation, Preclinical, Drug Resistance, Computational biology, Pharmacology, Antimalarials, Structure-Activity Relationship, medicine, Animals, Cluster Analysis, Structure–activity relationship, Parasites, Multidisciplinary, biology, Computational Biology, Reproducibility of Results, biology.organism_classification, Small molecule, Malaria, Tetrahydrofolate Dehydrogenase, Mechanism of action, Cheminformatics, Physical Sciences, Folic Acid Antagonists, medicine.symptom
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366c309405db5e001ca5fcec007def90
https://doi.org/10.1073/pnas.0802982105 -
4
المؤلفون: Yu Wang, Michel Fink, Achim Brinker, Jason Chyba, Puiying A. Mak, Genevieve Welch, Emmanuel Claret, Jeremy S. Caldwell, Paul A. Anderson, Anthony P. Orth, Jason T. Matzen, Michael Garcia, Timothy R. Smith, Deanna G Adams, Orzala Shalizi
المصدر: Current Chemical Genomics
مصطلحات موضوعية: chemistry.chemical_classification, Genetics, Chemistry, cDNA library, Drug discovery, Kinase, Cellular Assay, Peptide, Biochemistry, Article, Substrate-level phosphorylation, Molecular Medicine, Molecular Biology, Protein kinase B, G protein-coupled receptor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36de1353559f9c1455fbb45fbbb6b00e
https://doi.org/10.2174/1875397300801010054 -
5
المؤلفون: Ingo H. Engels, Jie Xu, Andrew M. Schumacher, Mauricio Montal, Ardem Patapoutian, David C. Tully, Michael Bandell, Bertrand Coste, H. Michael Petrassi, Truc Huynh, Adrienne E. Dubin, Jianmin Lao, Jayanti Mathur, Jason T. Matzen, Ruhma Syeda
مصطلحات موضوعية: Chemistry, PIEZO1, Biophysics, Channel (broadcasting), Mechanotransduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ccc77fd24b055190a28d6739a4e590f2
https://doi.org/10.7554/elife.07369.008 -
6
المؤلفون: Jianmin Lao, Michael Bandell, H. Michael Petrassi, David C. Tully, Truc Huynh, Adrienne E. Dubin, Jie Xu, Jason T. Matzen, Jayanti Mathur, Mauricio Montal, Ruhma Syeda, Bertrand Coste, Andrew M. Schumacher, Ardem Patapoutian, Ingo H. Engels
المساهمون: Laboratoire de Neurosciences Cognitives [Marseille] (LNC), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)
المصدر: eLife, Vol 4 (2015)
eLife
eLife, eLife Sciences Publication, 2015, 4, ⟨10.7554/eLife.07369⟩
eLife, 2015, 4, ⟨10.7554/eLife.07369⟩مصطلحات موضوعية: QH301-705.5, [SDV]Life Sciences [q-bio], Science, General Biochemistry, Genetics and Molecular Biology, Cell membrane, medicine, Mechanotransduction, Biology (General), agonist, Ion channel, mechanotransduction, General Immunology and Microbiology, Artificial cell, Chemistry, General Neuroscience, PIEZO1, Small Molecule Libraries, General Medicine, Anatomy, medicine.anatomical_structure, Membrane, Structural biology, ion channel, Biophysics, Medicine
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المؤلفون: Adam L. Orr, Renata L.S. Goncalves, Edward K. Ainscow, H. Michael Petrassi, Irina V. Perevoshchikova, Martin D. Brand, Douglas C Quackenbush, Leonardo Vargas, Stephen J Attle, Shelly Meeusen, Carolina N. Turk, Jing Li, Janine E. Baaten, Jason T. Matzen, Victoria J. Dardov
المصدر: Nature chemical biology
مصطلحات موضوعية: Male, Antimycin A, Oxidative phosphorylation, Mitochondrion, Biology, medicine.disease_cause, Article, Oxidative Phosphorylation, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Electron Transport Complex III, 0302 clinical medicine, Adenosine Triphosphate, Superoxides, Insulin-Secreting Cells, medicine, Animals, Humans, Rats, Wistar, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Reactive oxygen species, Dose-Response Relationship, Drug, Superoxide, Cell Biology, Free Radical Scavengers, Hydrogen Peroxide, High-Throughput Screening Assays, Mitochondria, Rats, Oxidative Stress, HEK293 Cells, Pyrimidines, chemistry, Biochemistry, Coenzyme Q – cytochrome c reductase, Retrograde signaling, Pyrazoles, Female, 030217 neurology & neurosurgery, Oxidative stress, Signal Transduction
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المؤلفون: Hayk Asatryan, Drew Gunderson, Frederick J. King, Sungjoon Kim, Jason T. Matzen, Daniel G. Sipes, Gang Xia, S. Frank Yan, Andrew I. Su, Jeremy S. Caldwell, Alham Saadat, Markus Warmuth, Peter G. Schultz, Tami Hood, Xiang-ju Gu, Ronak Beigi, Laura Jarnes, Jeff Janes, Michael Garcia, Jonathan S. Melnick, Richard A. Harig, Jim Yuchen Chang, Vicki Zhou, Christopher M. Shaw, Yingyao Zhou, Nathanael S. Gray, Robert T. Downs
المصدر: Proceedings of the National Academy of Sciences. 103:3153-3158
مصطلحات موضوعية: Time Factors, Multidisciplinary, ABL, Databases, Factual, Kinase, Phosphotransferases, Drug Evaluation, Preclinical, Reproducibility of Results, Robotics, Molecular Pharmacology, Computational biology, Biological Sciences, Biology, Small molecule, Molecular biology, Cell Line, Automation, Mice, Structure-Activity Relationship, Drug development, Growth factor receptor, Animals, Structure–activity relationship, Protein Kinase Inhibitors, Proto-oncogene tyrosine-protein kinase Src
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85ea39d8267429bf0bd1743f5ae5680
https://doi.org/10.1073/pnas.0511292103 -
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المؤلفون: Drew Gunderson, Jason T. Matzen, Jeremy S. Caldwell, Karen Wolff, Kelli Kuhen, Hong Yin, Joanna Hale, Scott A. Lesley, Kirk Niswonger, Heath E. Klock, Achim Brinker, Yu Wang, Kimberly Bieza
المصدر: SLAS Discovery. 10:456-462
مصطلحات موضوعية: 0301 basic medicine, Time Factors, medicine.drug_class, Drug Evaluation, Preclinical, HIV Integrase, Biology, Antiviral Agents, 01 natural sciences, Biochemistry, Virus, Cell Line, Analytical Chemistry, Inhibitory Concentration 50, 03 medical and health sciences, Cell Line, Tumor, High-Throughput Screening Assays, Fluorescence Resonance Energy Transfer, medicine, Humans, HIV Integrase Inhibitors, Cloning, Molecular, chemistry.chemical_classification, Dose-Response Relationship, Drug, Models, Genetic, Biological activity, Provirus, Molecular biology, Small molecule, 0104 chemical sciences, Integrase, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Enzyme, chemistry, Phosphatidylcholines, biology.protein, Molecular Medicine, Antiviral drug, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28eae10c1911c95fe0e086fd9b68aa8f
https://doi.org/10.1177/1087057105275212 -
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المؤلفون: Paul Anderson, Edward Nigoghossian, Heath E. Klock, Mark W. Knuth, Eric Hampton, Tetsuo Uno, Orzala Sharif, Richard E. Trager, Huiyong Hu, Richard Glynne, Jason T. Matzen, Sassan M. Azarian, Jeremy S. Caldwell, Achim Brinker
المصدر: Analytical biochemistry. 392(2)
مصطلحات موضوعية: Time Factors, medicine.drug_class, Biophysics, Retinoic acid, Drug Evaluation, Preclinical, Biochemistry, chemistry.chemical_compound, Retinoids, medicine, Fluorescence Resonance Energy Transfer, Humans, Prealbumin, Retinoid, Surface plasmon resonance, Molecular Biology, Retinol binding protein 4, biology, Molecular Structure, Chemistry, Ligand binding assay, Cell Biology, Surface Plasmon Resonance, Small molecule, Retinol binding protein, Fenretinide, biology.protein, Retinol-Binding Proteins, Plasma, Protein Binding