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1
المؤلفون: Mark A. Nagy, Robert Hilgraf, Deborah S. Mortensen, Jan Elsner, Stephen Norris, Jayashree Tikhe, Won Yoon, David Paisner, Mercedes Delgado, Paul Erdman, Jason Haelewyn, Godrej Khambatta, Li Xu, William J. Romanow, Kevin Condroski, Sogole Bahmanyar, Meg McCarrick, Brent Benish, Kate Blease, Laurie LeBrun, Mehran F. Moghaddam, Julius Apuy, Stacie S. Canan, Brydon L. Bennett, Yoshitaka Satoh
المصدر: Journal of Medicinal Chemistry. 64:18193-18208
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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2
المؤلفون: Mark A, Nagy, Robert, Hilgraf, Deborah S, Mortensen, Jan, Elsner, Stephen, Norris, Jayashree, Tikhe, Won, Yoon, David, Paisner, Mercedes, Delgado, Paul, Erdman, Jason, Haelewyn, Godrej, Khambatta, Li, Xu, William J, Romanow, Kevin, Condroski, Sogole, Bahmanyar, Meg, McCarrick, Brent, Benish, Kate, Blease, Laurie, LeBrun, Mehran F, Moghaddam, Julius, Apuy, Stacie S, Canan, Brydon L, Bennett, Yoshitaka, Satoh
المصدر: Journal of medicinal chemistry. 64(24)
مصطلحات موضوعية: Cyclohexylamines, Structure-Activity Relationship, Pyrimidines, Drug Discovery, JNK Mitogen-Activated Protein Kinases, Animals, Humans, Phosphorylation, Protein Kinase Inhibitors, Idiopathic Pulmonary Fibrosis, Substrate Specificity
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3
المؤلفون: Babine Robert E, Edward L. Brown, David A. Matthews, Susan L. Binford, Stephen T. Worland, Shella A. Fuhrman, Amy K. Patick, James E. V. Harr, Reich Siegfried Heinz, Joseph T. Marakovits, Thomas J. Prins, Caroline A. Lee, Wallace Michael B, Peter S. Dragovich, Littlefield Ethel S, and Dorothy M. DeLisle, James W. Meador, Rose Ann Ferre, Clifford E. Ford, Ru Zhou, Stephen E. Webber, Jayashree Tikhe
المصدر: Journal of Medicinal Chemistry. 41:2819-2834
مصطلحات موضوعية: Rhinovirus, Picornain 3C, Stereochemistry, Drug Evaluation, Preclinical, Peptide, Tripeptide, Cysteine Proteinase Inhibitors, Crystallography, X-Ray, Antiviral Agents, Chemical synthesis, Structure-Activity Relationship, Viral Proteins, chemistry.chemical_compound, Drug Discovery, Humans, Structure–activity relationship, Cell Line, Transformed, chemistry.chemical_classification, Binding Sites, Dipeptide, biology, 3C Viral Proteases, Cysteine Endopeptidases, chemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Oligopeptides
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4
المؤلفون: Edward L. Brown, Susan L. Binford, Amy K. Patick, Shella A. Fuhrman, Rose Ann Ferre, D. M. Delisle, R. A. Love, Jayashree Tikhe, Stephen E. Webber, James W. Meador, Thomas F. Hendrickson, David A. Matthews, Stephen T. Worland, Clifford E. Ford
المصدر: Journal of Medicinal Chemistry. 39:5072-5082
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Molecular model, Picornain 3C, medicine.drug_class, Stereochemistry, Carboxamide, Antiviral Agents, Chemical synthesis, Mass Spectrometry, Viral Proteins, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Protease Inhibitors, Chymotrypsin, Molecular Structure, biology, Isatin, 3C Viral Proteases, Proteolytic enzymes, Active site, Cysteine Endopeptidases, chemistry, biology.protein, Thermodynamics, Molecular Medicine, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb4276743bdc1e96c88b9e79ec6479e
https://doi.org/10.1021/jm960603e -
5
المؤلفون: R. A. Love, Stephen T. Worland, D. M. Delisle, Jayashree Tikhe, Edward L. Brown, Susan L. Binford, Thomas F. Hendrickson, Rose Ann Ferre, Shella A. Fuhrman, David A. Matthews, James W. Meador, Clifford E. Ford, Amy K. Patick, Stephen E. Webber
المصدر: ChemInform. 28
مصطلحات موضوعية: Chymotrypsin, medicine.diagnostic_test, biology, Molecular model, Stereochemistry, Isatin, Proteolysis, Proteolytic enzymes, Active site, General Medicine, chemistry.chemical_compound, Protein structure, chemistry, medicine, biology.protein, Cysteine
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المؤلفون: Peter S. Dragovich, Stephen E. Webber, Robert E. Babine, Shella A. Fuhrman, Amy K. Patick, David A. Matthews, Caroline A. Lee, Siegfried H. Reich, Thomas J. Prins, Joseph T. Marakovits, Ethel S. Littlefield, Ru Zhou, Jayashree Tikhe, Clifford E. Ford, Michael B. Wallace, James W. Meador, Rose Ann Ferre, Edward L. Brown, Susan L. Binford, James E. V. Harr, Dorothy M. DeLisle, Stephen T. Worland
المصدر: Journal of medicinal chemistry. 41(15)
مصطلحات موضوعية: Binding Sites, Rhinovirus, Protein Conformation, 3C Viral Proteases, Cysteine Proteinase Inhibitors, Crystallography, X-Ray, Antiviral Agents, Rats, Rats, Sprague-Dawley, Cysteine Endopeptidases, Structure-Activity Relationship, Viral Proteins, Drug Stability, Drug Design, Drug Discovery, Molecular Medicine, Animals, Humans, Oligopeptides, Cell Line, Transformed, HeLa Cells