المؤلفون: Amar D; Stanford University, Stanford, CA, USA; Insitro, San Francisco, CA, USA., Gay NR; Stanford University, Stanford, CA, USA., Jimenez-Morales D; Stanford University, Stanford, CA, USA., Jean Beltran PM; Broad Institute, Boston, MA, USA., Ramaker ME; Duke University, Durham, NC, USA., Raja AN; Stanford University, Stanford, CA, USA., Zhao B; Stanford University, Stanford, CA, USA., Sun Y; Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Marwaha S; Stanford University, Stanford, CA, USA., Gaul DA; Georgia Institute of Technology, Atlanta, GA, USA., Hershman SG; Stanford University, Stanford, CA, USA., Ferrasse A; Stanford University, Stanford, CA, USA., Xia A; National Institutes of Health, Bethesda, MD, USA., Lanza I; The Mayo Clinic, Rochester, MN, USA., Fernández FM; Georgia Institute of Technology, Atlanta, GA, USA., Montgomery SB; Stanford University, Stanford, CA, USA., Hevener AL; University of California, Los Angeles, Los Angeles, CA, USA., Ashley EA; Stanford University, Stanford, CA, USA., Walsh MJ; Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Sparks LM; Translational Research Institute AdventHealth, Orlando, FL, USA., Burant CF; University of Michigan, Ann Arbor, MI, USA., Rector RS; University of Missouri, Columbia, MO, USA., Thyfault J; University of Kansas Medical Center, Kansas City, KS, USA., Wheeler MT; Stanford University, Stanford, CA, USA., Goodpaster BH; Translational Research Institute AdventHealth, Orlando, FL, USA., Coen PM; Translational Research Institute AdventHealth, Orlando, FL, USA., Schenk S; University of California, San Diego, La Jolla, CA, USA., Bodine SC; Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Lindholm ME; Stanford University, Stanford, CA, USA. Electronic address: malenel@stanford.edu.

مؤلفون مشاركون: MoTrPAC Study Group

المصدر: Cell metabolism [Cell Metab] 2024 Jun 04; Vol. 36 (6), pp. 1411-1429.e10. Date of Electronic Publication: 2024 May 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE

مواضيع طبية MeSH: Physical Conditioning, Animal* , Mitochondria*/metabolism, Animals ; Male ; Female ; Rats ; Muscle, Skeletal/metabolism ; Humans ; Rats, Sprague-Dawley ; Adipose Tissue, Brown/metabolism ; Adrenal Glands/metabolism ; Multiomics

المؤلفون: Mansur A; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States., Joseph R; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States., Kim ES; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States., Jean-Beltran PM; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Udeshi ND; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Pearce C; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Jiang H; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States.; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Boston, United States., Iwase R; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, United States., Milev MP; Department of Biology, Concordia University of Edmonton, Montreal, Canada., Almousa HA; Department of Biology, Concordia University of Edmonton, Montreal, Canada., McNamara E; Faculty of Health and Medical Sciences, Centre of Medical Research, Harry Perkins Institute of Medical Research, University of Western Australia, Perth, Australia., Widrick J; Division of Genetics, Boston Children's Hospital, Harvard Medical School, Boston, United States., Perez C; Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, United States., Ravenscroft G; Faculty of Health and Medical Sciences, Centre of Medical Research, Harry Perkins Institute of Medical Research, University of Western Australia, Perth, Australia., Sacher M; Department of Biology, Concordia University of Edmonton, Montreal, Canada.; Department of Anatomy and Cell Biology, McGill University, Montreal, Canada., Cole PA; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States., Carr SA; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Gupta VA; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States.

المصدر: ELife [Elife] 2023 Jul 11; Vol. 12. Date of Electronic Publication: 2023 Jul 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Muscle Proteins*/genetics , Muscle Proteins*/metabolism , Zebrafish*/metabolism, Animals ; Humans ; Proteome/metabolism ; Muscle, Skeletal/metabolism ; Ubiquitination ; Sarcomeres/metabolism ; Ubiquitin/metabolism ; Endoplasmic Reticulum/metabolism ; Muscle Development ; Disease Progression

المؤلفون: Flaherty SE 3rd; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Bezy O; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Zheng W; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Yan D; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Li X; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Jagarlapudi S; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Albuquerque B; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Esquejo RM; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Peloquin M; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Semache M; Domain Therapeutics North America, Montréal, QC, Canada., Mancini A; Domain Therapeutics North America, Montréal, QC, Canada., Kang L; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Drujan D; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Breitkopf SB; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Griffin JD; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Jean Beltran PM; Machine Learning and Computational Sciences, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Xue L; Machine Learning and Computational Sciences, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Stansfield J; Biostatistics, Early Clinical Development, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Pashos E; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Shakey Q; Biomedicine design, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Pehmøller C; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Monetti M; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Birnbaum MJ; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Fortin JP; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Wu Z; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA. Zhidan.wu@pfizer.com.

المصدر: Nature communications [Nat Commun] 2023 Jul 04; Vol. 14 (1), pp. 3953. Date of Electronic Publication: 2023 Jul 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Insulin Resistance*, Animals ; Male ; Mice ; Corticotropin-Releasing Hormone/genetics ; Corticotropin-Releasing Hormone/metabolism ; Glucose/metabolism ; Insulin ; Ligands ; Receptors, Corticotropin-Releasing Hormone/genetics ; Receptors, Corticotropin-Releasing Hormone/metabolism ; Urocortins/genetics ; Urocortins/metabolism

المؤلفون: Wu CH; Department of Biology, Brandeis University, Waltham, United States., Tatavarty V; Department of Biology, Brandeis University, Waltham, United States., Jean Beltran PM; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Guerrero AA; Department of Biology, Brandeis University, Waltham, United States., Keshishian H; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Krug K; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., MacMullan MA; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Li L; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, United States., Carr SA; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Cottrell JR; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, United States., Turrigiano GG; Department of Biology, Brandeis University, Waltham, United States.

المصدر: ELife [Elife] 2022 Apr 26; Vol. 11. Date of Electronic Publication: 2022 Apr 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Autism Spectrum Disorder*/metabolism, Animals ; Bias ; Mice ; Microfilament Proteins/metabolism ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Neuronal Plasticity/physiology ; Phosphorylation ; Proteomics ; Rats ; Synapses/physiology

المؤلفون: Cygan AM; Department of Microbiology and Immunology, Stanford School of Medicine, Stanford California, USA., Jean Beltran PM; Broad Institutegrid.66859.34 of MIT and Harvard, Cambridge, Massachusetts, USA., Mendoza AG; Department of Microbiology and Immunology, Stanford School of Medicine, Stanford California, USA., Branon TC; Department of Chemistry, Stanford Universitygrid.168010.e, Stanford, California, USA., Ting AY; Department of Chemistry, Stanford Universitygrid.168010.e, Stanford, California, USA., Carr SA; Broad Institutegrid.66859.34 of MIT and Harvard, Cambridge, Massachusetts, USA., Boothroyd JC; Department of Microbiology and Immunology, Stanford School of Medicine, Stanford California, USA.

المصدر: MBio [mBio] 2021 Dec 21; Vol. 12 (6), pp. e0026021. Date of Electronic Publication: 2021 Nov 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

مواضيع طبية MeSH: Intracellular Membranes/*metabolism , Intracellular Membranes/*parasitology , Protozoan Proteins/*metabolism , Toxoplasma/*metabolism , Toxoplasmosis/*metabolism , Toxoplasmosis/*parasitology , Vacuoles/*parasitology, Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Endosomal Sorting Complexes Required for Transport/genetics ; Endosomal Sorting Complexes Required for Transport/metabolism ; Host-Parasite Interactions ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Protein Transport ; Protozoan Proteins/genetics ; Receptors, Chemokine/genetics ; Receptors, Chemokine/metabolism ; Toxoplasma/genetics ; Toxoplasmosis/genetics ; Vacuoles/genetics ; Vacuoles/metabolism

المؤلفون: Keshishian H; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., McDonald ER 3rd; Novartis Institute of Biomedical Research, Cambridge, MA, USA., Mundt F; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Melanson R; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Krug K; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Porter DA; Novartis Institute of Biomedical Research, Cambridge, MA, USA., Wallace L; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Forestier D; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Rabasha B; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Marlow SE; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Jane-Valbuena J; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Todres E; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Specht H; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Robinson ML; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Jean Beltran PM; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Babur O; Computer Science Department, University of Massachusetts Boston, Boston, MA, USA., Olive ME; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Golji J; Novartis Institute of Biomedical Research, Cambridge, MA, USA., Kuhn E; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Burgess M; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., MacMullan MA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Rejtar T; Novartis Institute of Biomedical Research, Cambridge, MA, USA., Wang K; Novartis Institute of Biomedical Research, Cambridge, MA, USA., Mani DR; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Satpathy S; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Gillette MA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, USA., Sellers WR; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Carr SA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.

المصدر: Molecular systems biology [Mol Syst Biol] 2021 Sep; Vol. 17 (9), pp. e10156.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: EMBO Press Country of Publication: England NLM ID: 101235389 Publication Model: Print Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE

مواضيع طبية MeSH: Phosphoproteins*/genetics , Phosphoproteins*/metabolism , Proteomics*, Humans ; Mass Spectrometry ; Phosphorylation ; Signal Transduction

المؤلفون: Betsinger CN; Lewis Thomas Laboratory, Department of Molecular Biology, Princeton University, Princeton, NJ 08544., Jankowski CSR; Lewis Thomas Laboratory, Department of Molecular Biology, Princeton University, Princeton, NJ 08544., Hofstadter WA; Lewis Thomas Laboratory, Department of Molecular Biology, Princeton University, Princeton, NJ 08544., Federspiel JD; Lewis Thomas Laboratory, Department of Molecular Biology, Princeton University, Princeton, NJ 08544., Otter CJ; Lewis Thomas Laboratory, Department of Molecular Biology, Princeton University, Princeton, NJ 08544., Jean Beltran PM; Lewis Thomas Laboratory, Department of Molecular Biology, Princeton University, Princeton, NJ 08544., Cristea IM; Lewis Thomas Laboratory, Department of Molecular Biology, Princeton University, Princeton, NJ 08544 icristea@princeton.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Aug 10; Vol. 118 (32).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Cytomegalovirus/*physiology , Cytomegalovirus Infections/*metabolism , Mitochondria/*metabolism , Mitochondria/*virology , Viral Proteins/*metabolism, Cytomegalovirus/metabolism ; Cytomegalovirus/pathogenicity ; Cytomegalovirus Infections/virology ; Electron Transport ; Host-Pathogen Interactions/physiology ; Humans ; Mitochondria/ultrastructure ; Oxidative Phosphorylation ; Viral Proteins/genetics ; Virus Replication

المؤلفون: Satpathy S; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA. Electronic address: shankha@broadinstitute.org., Krug K; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Jean Beltran PM; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Savage SR; Lester and Sue Smith Breast Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Petralia F; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Kumar-Sinha C; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Dou Y; Lester and Sue Smith Breast Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Reva B; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Kane MH; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Avanessian SC; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Vasaikar SV; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Krek A; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Lei JT; Lester and Sue Smith Breast Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Jaehnig EJ; Lester and Sue Smith Breast Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Omelchenko T; Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Geffen Y; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Bergstrom EJ; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Stathias V; Sylvester Comprehensive Cancer Center and Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA., Christianson KE; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Heiman DI; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Cieslik MP; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Cao S; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Song X; Department of Population Health Science and Policy, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Ji J; Department of Population Health Science and Policy, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Liu W; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA., Li K; Lester and Sue Smith Breast Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Wen B; Lester and Sue Smith Breast Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Li Y; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Gümüş ZH; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Selvan ME; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Soundararajan R; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Visal TH; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Raso MG; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Parra ER; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Babur Ö; Computer Science Department, University of Massachusetts Boston, Boston, MA 02125, USA., Vats P; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Anand S; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Schraink T; Institute for Systems Genetics and Department of Medicine, NYU Grossman School of Medicine, New York, NY 10016, USA., Cornwell M; Institute for Systems Genetics and Department of Medicine, NYU Grossman School of Medicine, New York, NY 10016, USA., Rodrigues FM; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Zhu H; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Mo CK; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Zhang Y; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., da Veiga Leprevost F; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Huang C; Lester and Sue Smith Breast Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Chinnaiyan AM; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Wyczalkowski MA; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Omenn GS; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Newton CJ; Van Andel Research Institute, Grand Rapids, MI 49503, USA., Schurer S; Sylvester Comprehensive Cancer Center and Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA., Ruggles KV; Institute for Systems Genetics and Department of Medicine, NYU Grossman School of Medicine, New York, NY 10016, USA., Fenyö D; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA., Jewell SD; Van Andel Research Institute, Grand Rapids, MI 49503, USA., Thiagarajan M; Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Mesri M; Office of Cancer Clinical Proteomics Research, National Cancer Institute, Bethesda, MD 20892, USA., Rodriguez H; Office of Cancer Clinical Proteomics Research, National Cancer Institute, Bethesda, MD 20892, USA., Mani SA; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Udeshi ND; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Getz G; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Suh J; Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Li QK; Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins Medical Institutions, Baltimore, MD 21224, USA., Hostetter G; Van Andel Research Institute, Grand Rapids, MI 49503, USA., Paik PK; Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Dhanasekaran SM; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Govindan R; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Ding L; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Robles AI; Office of Cancer Clinical Proteomics Research, National Cancer Institute, Bethesda, MD 20892, USA., Clauser KR; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Nesvizhskii AI; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Wang P; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Carr SA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA. Electronic address: scarr@broad.mit.edu., Zhang B; Lester and Sue Smith Breast Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: bing.zhang@bcm.edu., Mani DR; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA. Electronic address: manidr@broadinstitute.org., Gillette MA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA 02115, USA. Electronic address: gillette@broadinstitute.org.

مؤلفون مشاركون: Clinical Proteomic Tumor Analysis Consortium

المصدر: Cell [Cell] 2021 Aug 05; Vol. 184 (16), pp. 4348-4371.e40.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Proteogenomics*, Carcinoma, Squamous Cell/*genetics , Lung Neoplasms/*genetics, Acetylation ; Adult ; Aged ; Aged, 80 and over ; Cluster Analysis ; Cyclin-Dependent Kinase 4/genetics ; Cyclin-Dependent Kinase 6/genetics ; Epithelial-Mesenchymal Transition/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Mutation/genetics ; Neoplasm Proteins/metabolism ; Phosphorylation ; Protein Binding ; Receptor Tyrosine Kinase-like Orphan Receptors/metabolism ; Receptors, Platelet-Derived Growth Factor/metabolism ; Signal Transduction ; Ubiquitination

المؤلفون: Renneville A; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; INSERM U1287, Gustave Roussy Cancer Campus, Villejuif, France., Gasser JA; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Grinshpun DE; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Jean Beltran PM; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Udeshi ND; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Matyskiela ME; Celgene/Bristol-Myers Squibb Corporation, San Diego, California., Clayton T; Celgene/Bristol-Myers Squibb Corporation, San Diego, California., McConkey M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Viswanathan K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Tepper A; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Guirguis AA; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Sellar RS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Haematology, UCL Cancer Institute, London, United Kingdom., Cotteret S; Département de Biologie et Pathologie, Gustave Roussy Cancer Campus, Villejuif, France., Marzac C; Département de Biologie et Pathologie, Gustave Roussy Cancer Campus, Villejuif, France., Saada V; Département de Biologie et Pathologie, Gustave Roussy Cancer Campus, Villejuif, France., De Botton S; Département d'Hématologie, Gustave Roussy Cancer Campus, Villejuif, France., Kiladjian JJ; Université de Paris, AP-HP, Hôpital Saint-Louis, Centre d'Investigations Cliniques CIC 1427, INSERM, Paris, France., Cayuela JM; Hematology Laboratory and EA3518, University Hospital Saint-Louis, Université de Paris, Paris, France., Rolfe M; Celgene/Bristol-Myers Squibb Corporation, San Diego, California., Chamberlain PP; Celgene/Bristol-Myers Squibb Corporation, San Diego, California., Carr SA; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Ebert BL; Broad Institute of MIT and Harvard, Cambridge, Massachusetts. Benjamin_Ebert@dfci.harvard.edu.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Howard Hughes Medical Institute, Dana-Farber Cancer Institute, Boston, Massachusetts.

المصدر: Blood cancer discovery [Blood Cancer Discov] 2021 May; Vol. 2 (3), pp. 250-265. Date of Electronic Publication: 2021 Mar 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101764786 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2643-3249 (Electronic) Linking ISSN: 26433230 NLM ISO Abbreviation: Blood Cancer Discov

مواضيع طبية MeSH: Hematologic Neoplasms*/drug therapy , Thalidomide*, DNA-Binding Proteins ; Humans ; Lenalidomide/pharmacology ; Oncogene Proteins ; Transcription Factors/metabolism

المؤلفون: Federspiel JD; Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA., Cook KC; Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA., Kennedy MA; Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA., Venkatesh SS; Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA., Otter CJ; Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA., Hofstadter WA; Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA., Jean Beltran PM; Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA., Cristea IM; Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA. Electronic address: icristea@princeton.edu.

المصدر: Cell reports [Cell Rep] 2020 Jul 28; Vol. 32 (4), pp. 107943.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Computational Biology/*methods , Mitochondria/*metabolism , Protein Interaction Maps/*physiology, Cell Line ; Cytomegalovirus/physiology ; Cytomegalovirus Infections/virology ; Endoplasmic Reticulum/metabolism ; Fibroblasts/metabolism ; Host Microbial Interactions/physiology ; Humans ; Immediate-Early Proteins/genetics ; Mitochondrial Membranes/metabolism ; Peroxisomes/metabolism