يعرض 1 - 10 نتائج من 24 نتيجة بحث عن '"Jean-François Bonfanti"', وقت الاستعلام: 1.16s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation

    المؤلفون: Dominik Kiemel, Ann-Sophie Helene Kroell, Solène Denolly, Uta Haselmann, Jean-François Bonfanti, Jose Ignacio Andres, Brahma Ghosh, Peggy Geluykens, Suzanne J. F. Kaptein, Lucas Wilken, Pietro Scaturro, Johan Neyts, Marnix Van Loock, Olivia Goethals, Ralf Bartenschlager

    المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

    مصطلحات موضوعية: Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2041-1723

    URL الوصول: https://doaj.org/article/e78ff1b130a7428d836ca61a6614a777

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  2. 2
    دورية أكاديمية
    Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model.

    المؤلفون: Gabriela Ispas, Anil Koul, Johan Verbeeck, Jennifer Sheehan, Brigitte Sanders-Beer, Dirk Roymans, Koen Andries, Marie-Claude Rouan, Sandra De Jonghe, Jean-François Bonfanti, Marc Vanstockem, Kenneth Simmen, Rene Verloes

    المصدر: PLoS ONE, Vol 10, Iss 5, p e0126959 (2015)

    مصطلحات موضوعية: Medicine, Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/1932-6203

    URL الوصول: https://doaj.org/article/f305416d7c6540b8927222167c47ba8d

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  3. 3
    Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates

    المؤلفون: Olivia Goethals, Suzanne J. F. Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J. Verschoor, Babs E. Verstrepen, Zahra Fagrouch, J. Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K. McCracken, Gregory D. Gromowski, Wiriya Rutvisuttinunt, Richard G. Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier de Lamballerie, Laurent Chatel-Chaix, Gregg N. Milligan, David W. C. Beasley, Nigel Bourne, Alan D. T. Barrett, Arnaud Marchand, Tim H. M. Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf Bartenschlager, Willy M. Bogers, Johan Neyts, Marnix Van Loock

    المصدر: Nature. 615:678-686

    مصطلحات موضوعية: Multidisciplinary

    وصف الملف: Print-Electronic

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8c0a4183f19bf33ac0d110d21b457f
    https://doi.org/10.1038/s41586-023-05790-6

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  4. 4
    From Oxetane to Thietane: Extending the Antiviral Spectrum of 2′-Spirocyclic Uridines by Substituting Oxygen with Sulfur

    المؤلفون: Sandrine Grosse, Abdellah Tahri, Pierre Raboisson, Yannis Houpis, Bart Stoops, Edgar Jacoby, Jean-Marc Neefs, Marnix Van Loock, Olivia Goethals, Peggy Geluykens, Jean-François Bonfanti, Tim H. M. Jonckers

    المصدر: ACS Medicinal Chemistry Letters. 13:1879-1884

    مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a6a84c256df58b86b9b102ba666666
    https://doi.org/10.1021/acsmedchemlett.2c00372

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  5. 5
    دورية أكاديمية
    A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction

    المؤلفون: Suzanne J. F. Kaptein, Olivia Goethals, Dominik Kiemel, Arnaud Marchand, Bart Kesteleyn, Jean-François Bonfanti, Dorothée Bardiot, Bart Stoops, Tim H. M. Jonckers, Kai Dallmeier, Peggy Geluy

    المصدر: Nature, Nature. 598(7881):504-509

    الإتاحة: https://ideas.repec.org/a/nat/nature/v598y2021i7881d10.1038_s41586-021-03990-6.html

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  6. 6
    A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction

    المؤلفون: Bart Rudolf Romanie Kesteleyn, Suzanne J.F. Kaptein, Xavier de Lamballerie, Kenny Simmen, Arnaud Marchand, Jean-François Bonfanti, Max Münster, Laurent Chatel-Chaix, Marjolein Crabbe, Johan Neyts, Marnix Van Loock, Kai Dallmeier, Gilles Querat, Franck Touret, Kim Thys, Olivia Goethals, Dorothée Bardiot, Tim H. M. Jonckers, Pierre Jean-Marie Bernard Raboisson, Peggy Geluykens, Dominik Kiemel, Patrick Chaltin, Bart Stoops, Ralf Bartenschlager

    مصطلحات موضوعية: Serotype, NS3, Multidisciplinary, Science & Technology, viruses, NS4B, Biology, Dengue virus, medicine.disease, medicine.disease_cause, Virology, Dengue fever, Multidisciplinary Sciences, Viral replication complex, Genotype, REPLICATION, medicine, Science & Technology - Other Topics, Viral load

    وصف الملف: Print-Electronic

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0f695891d12a95fecae329bcce0424
    https://lirias.kuleuven.be/handle/123456789/683277

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  7. 7
    A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction

    المؤلفون: Suzanne J F, Kaptein, Olivia, Goethals, Dominik, Kiemel, Arnaud, Marchand, Bart, Kesteleyn, Jean-François, Bonfanti, Dorothée, Bardiot, Bart, Stoops, Tim H M, Jonckers, Kai, Dallmeier, Peggy, Geluykens, Kim, Thys, Marjolein, Crabbe, Laurent, Chatel-Chaix, Max, Münster, Gilles, Querat, Franck, Touret, Xavier, de Lamballerie, Pierre, Raboisson, Kenny, Simmen, Patrick, Chaltin, Ralf, Bartenschlager, Marnix, Van Loock, Johan, Neyts

    المصدر: Nature. 598(7881)

    مصطلحات موضوعية: Male, Serine Endopeptidases, Membrane Proteins, Dengue Virus, Viral Load, Viral Nonstructural Proteins, Virus Replication, Antiviral Agents, Dengue, Disease Models, Animal, Mice, Animals, Female, Viremia, RNA Helicases

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e4e1de640eac35dd21665b2d7bca5ffa
    https://pubmed.ncbi.nlm.nih.gov/34697477

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  8. 8
    Practical Synthesis of Ethyl 3-Fluoro-1-pyrrole-2-carboxylate: A Key Fragment of a Potent Drug Candidate against Hepatitis B Virus

    المؤلفون: Xavier Pannecoucke, Yang Cheng, Philippe Jubault, Pierre Jean-Marie Bernard Raboisson, Maxime Quilan, Jean-François Bonfanti, Thomas Poisson, Jérôme Michel Claude Fortin, Christopher A. Teleha, André B. Charette, Adeline René, Yicheng Deng

    المساهمون: Chimie Organique et Bioorganique : Réactivité et Analyse (COBRA), Institut Normand de Chimie Moléculaire Médicinale et Macromoléculaire (INC3M), Institut de Chimie du CNRS (INC)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Normandie Université (NU)-Institut national des sciences appliquées Rouen Normandie (INSA Rouen Normandie), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA)-Université Le Havre Normandie (ULH), Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Institut de Chimie du CNRS (INC)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie Organique Fine (IRCOF), Université de Rouen Normandie (UNIROUEN), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: Organic Process Research and Development
    Organic Process Research and Development, American Chemical Society, 2019, 24 (5), pp.792-801. ⟨10.1021/acs.oprd.9b00382⟩

    مصطلحات موضوعية: Drug, Hepatitis B virus, 010405 organic chemistry, Fragment (computer graphics), Drug candidate, Chemistry, media_common.quotation_subject, Organic Chemistry, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, 3. Good health, chemistry.chemical_compound, Pyrrole-2-carboxylate, Yield (chemistry), medicine, [CHIM]Chemical Sciences, Physical and Theoretical Chemistry, media_common, Pyrrole

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b015a3edb520bf73beb6c0ceed04b8c4
    https://hal-normandie-univ.archives-ouvertes.fr/hal-02364011

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  9. 9
    دورية أكاديمية
    Publisher Correction: A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction

    المؤلفون: Suzanne J. F. Kaptein, Olivia Goethals, Dominik Kiemel, Arnaud Marchand, Bart Kesteleyn, Jean-François Bonfanti, Dorothée Bardiot, Bart Stoops, Tim H. M. Jonckers, Kai Dallmeier, Peggy Geluy

    المصدر: Nature, Nature. 599(7883):2-2

    الإتاحة: https://ideas.repec.org/a/nat/nature/v599y2021i7883d10.1038_s41586-021-04123-9.html

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  10. 10
    A novel pyrimidine forming cyclization

    المؤلفون: Marc van de Sande, Ruben Gerardus George Leenders, Jean-François Bonfanti

    المصدر: Tetrahedron Letters. 61:151369

    مصطلحات موضوعية: chemistry.chemical_compound, Pyrimidine, chemistry, Organic Chemistry, Drug Discovery, Biochemistry, Combinatorial chemistry

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::362e071a0369142191f4c8c4e46fa74d
    https://doi.org/10.1016/j.tetlet.2019.151369

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