-
1
المؤلفون: Marc Ravatin, Norbert Odolczyk, Nathalie Servel, J. Iñaki Guijarro, Eric Tagat, Benoit Chevalier, Nesrine Baatallah, Pierre-Jean Corringer, Gergely L. Lukács, Aleksander Edelman, Piotr Zielenkiewicz, Jean-Marie Chambard, Alexandre Hinzpeter, Grazyna Faure
المساهمون: Récepteurs Canaux - Channel Receptors, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Sanofi [Vitry-sur-Seine], SANOFI Recherche, University of Warsaw (UW), Polish Academy of Sciences (PAN), Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Plateforme Technologique de RMN Biologique et HDX-MS - Biological NMR and HDX-MS Technological Platform, McGill University = Université McGill [Montréal, Canada], The research leading to these results has received partial funding from the Association Vaincre La Mucoviscidose (VLM), France and Institut Pasteur grant RF20170502000/1/1/141 and from contract SANOFI-Aventis R&D/Institut Pasteur grant 199038. MR was recipient of a PhD-CIFR fellowship from SANOFI-Aventis R&D. The 800-MHz NMR spectrometer of the Institut Pasteur was partially funded by the Région Ile de France (SESAME 2014 NMRCHR grant 4014526)
المصدر: Journal of Molecular Biology
Journal of Molecular Biology, 2023, 435 (3), pp.167929. ⟨10.1016/j.jmb.2022.167929⟩مصطلحات موضوعية: protein-protein interaction, peptide design, phospholipase A(2), chloride channel potentiator, Structural Biology, cystic fibrosis therapeutics peptides, [SDV]Life Sciences [q-bio], Molecular Biology
-
2
المؤلفون: Céline Prévost, Eric Brohan, Odile Angouillant-Boniface, G.Andrees Böhme, Sylvie Houtmann, Céline Chantoiseau, Thierry Carriot, Veronique Ballet, Sophie Fouconnier, Laurent Schio, Michel Partiseti, Rachid Boukaiba, Jean-Marie Chambard, Brigitte Schombert
المصدر: European Journal of Pharmacology. 915:174670
مصطلحات موضوعية: Patch-Clamp Techniques, Purkinje fibers, hERG, Action Potentials, Pharmacology, Ion Channels, Membrane Potentials, Afterdepolarization, Purkinje Fibers, Antimalarials, Electrocardiography, medicine, Animals, Humans, Ion channel, biology, Chemistry, Arrhythmias, Cardiac, Heart, Stereoisomerism, Cardiac action potential, Resting potential, Ether-A-Go-Go Potassium Channels, Potassium channel, Electrophysiology, medicine.anatomical_structure, biology.protein, Rabbits, Electrophysiologic Techniques, Cardiac, Hydroxychloroquine
-
3
المؤلفون: Rémy Béroud, Laurent Bialy, Andrees Bohme, Jean-Marie Chambard, Michel De Waard, Laetitia Lucarain, Lucie Jaquillard, Denis Servent, Stéphane Hourcade, Michel Partiseti, Gerhard Hessler, Stéphanie Combemale, Brigitte Schombert, Michael Kurz, Sophie Fouconnier, Rachid Boukaiba, Tânia C. Gonçalves, Evelyne Benoit
المساهمون: Sanofi R & D, Integrated Drug Discovery, In Vitro Biology & Pharmacology, Service d'Ingénierie Moléculaire pour la Santé (ex SIMOPRO) (SIMoS), Médicaments et Technologies pour la Santé (MTS), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut des Neurosciences Paris-Saclay (NeuroPSI), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Smartox Biotechnology, Université Joseph Fourier - Grenoble 1 (UJF), Sanofi-Aventis Deutschland GmbH, Neuroscience Therapeutic Area, UCB BioPharma, INSERM U836, équipe 3, Canaux calciques, fonctions et pathologies, Grenoble Institut des Neurosciences (GIN), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), ANR-11-LABX-0015,ICST,Canaux ioniques d'intérêt thérapeutique(2011), Unité de recherche de l'institut du thorax (ITX-lab), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), BENOIT, Evelyne, Laboratoires d'excellence - Canaux ioniques d'intérêt thérapeutique - - ICST2011 - ANR-11-LABX-0015 - LABX - VALID
المصدر: Br J Pharmacol
British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2019, 176 (9), pp.1298-1314. ⟨10.1111/bph.14628⟩
British Journal of Pharmacology, 2019, 176 (9), pp.1298-1314. ⟨10.1111/bph.14628⟩مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], Narcotic Antagonists, Pain, Spider Venoms, Peptide, Venom, Voltage-Gated Sodium Channels, Pharmacology, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, In vivo, Animals, Humans, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], chemistry.chemical_classification, Analgesics, Sodium channel, Spiders, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, Research Papers, In vitro, [SDV] Life Sciences [q-bio], [SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, Electrophysiology, Disease Models, Animal, 030104 developmental biology, HEK293 Cells, chemistry, [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Tetrodotoxin, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Female, Inhibitor cystine knot, 030217 neurology & neurosurgery, Sodium Channel Blockers
وصف الملف: application/pdf
-
4
المؤلفون: Eric Tagat, Michel Partiseti, Philippe Boudeau, Jean-Marie Chambard
المصدر: SLAS Discovery. 19:468-477
مصطلحات موضوعية: Drug, Patch-Clamp Techniques, Computer science, media_common.quotation_subject, Drug Evaluation, Preclinical, Computational biology, Bioinformatics, Biochemistry, Cell Line, Analytical Chemistry, Mice, Transient receptor potential channel, Transient Receptor Potential Channels, Automated patch clamp, Drug Discovery, High-Throughput Screening Assays, Animals, Humans, Ion channel, media_common, Voltage-gated ion channel, Drug discovery, Electrophysiology, Molecular Medicine, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a90599487a5161e70bcc50de5d6a0f1
https://doi.org/10.1177/1087057113499632 -
5
المؤلفون: Thomas Licher, Daniel Bertrand, Jean-Marie Chambard, Isabel A. Lefevre, Bruno Biton, Michel Partiseti, Christophe Lanneau
المصدر: Current Protocols in Pharmacology
مصطلحات موضوعية: 0301 basic medicine, Electrophysiological Phenomena, Nanotechnology, Sodium Channels, Cell Line, Membrane Potentials, Mice, 03 medical and health sciences, 0302 clinical medicine, Sodium channel blocker, Drug Discovery, Animals, Humans, Functional studies, Physiological function, Drug discovery, Chemistry, Sodium channel, Genetic data, General Medicine, High-Throughput Screening Assays, Rats, 030104 developmental biology, Identification (biology), Neuroscience, 030217 neurology & neurosurgery, Sodium Channel Blockers
-
6
المؤلفون: Jonathan Ashmore, Sarah Richmond, Jean-Marie Chambard
المصدر: Audiology and Neurotology. 7:6-8
مصطلحات موضوعية: Monosaccharide Transport Proteins, Physiology, Glucose Transporter Type 5, Molecular Motor Proteins, Anion Transport Proteins, Gene Expression, Proteins, Transduction (psychology), Biology, Sensory Systems, Cochlear function, Cochlea, Hair Cells, Auditory, Outer, Speech and Hearing, Hearing, Otorhinolaryngology, Sulfate Transporters, Animals, Humans, Outer hair cells, Neuroscience, Signal Transduction
-
7
المؤلفون: Jean-Marie Chambard, Jonathan Ashmore
المصدر: Epithelial Anion Transport in Health and Disease: The Role of the SLC26 Transporters Family: Novartis Foundation Symposium 273
مصطلحات موضوعية: biology, Chemistry, Glucose transporter, Pendrin, Transport protein, medicine.anatomical_structure, Biochemistry, otorhinolaryngologic diseases, biology.protein, medicine, Biophysics, sense organs, Hair cell, Anion binding, Prestin, Intracellular, Epithelial polarity
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::739408813f73a31229d52eb910d16204
https://doi.org/10.1002/0470029579.ch5 -
8
المؤلفون: Jonathan, Ashmore, Jean-Marie, Chambard
المصدر: Novartis Foundation symposium. 273
مصطلحات موضوعية: Anion Transport Proteins, Animals, Carbohydrate Metabolism, Humans, Water
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::cc280c918070b3e52327c5243c882e16
https://pubmed.ncbi.nlm.nih.gov/17120761 -
9
المصدر: Neuroreport. 12(12)
مصطلحات موضوعية: Patch-Clamp Techniques, Potassium Channels, Sodium, chemistry.chemical_element, Cesium, Cyclic Nucleotide-Gated Cation Channels, Nerve Tissue Proteins, Cell Separation, Ion Channels, Membrane Potentials, Mice, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Animals, Patch clamp, Vestibular system, Membrane potential, Neurons, General Neuroscience, Vestibular pathway, Cardiovascular Agents, Anatomy, Hyperpolarization (biology), Electric Stimulation, Monovalent Cations, Electrophysiology, Pyrimidines, chemistry, Biophysics, Potassium, Vestibule, Labyrinth
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5e7f87518ef7acf5a4d2c620e40a1d
https://pubmed.ncbi.nlm.nih.gov/11522951 -
10
المصدر: Neuroreport. 8(5)
مصطلحات موضوعية: medicine.medical_specialty, Patch-Clamp Techniques, Sodium, Scarpa's ganglion, chemistry.chemical_element, Tetrodotoxin, Vestibular Nerve, Sodium Channels, Sodium current, chemistry.chemical_compound, Mice, Ganglia, Sensory, Internal medicine, medicine, Animals, Evoked Potentials, Vestibular system, Neurons, General Neuroscience, Electric Conductivity, Peak current, Electrophysiology, Endocrinology, chemistry, Biophysics, Voltage
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2682be6d72e9600369d550b2f1fd874e
https://pubmed.ncbi.nlm.nih.gov/9175124
