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1
المؤلفون: Jin Zhai, Mary Jo Wildey, Elisa Passini, John Imredy, Frederick Sannajust, Kevin Fitzgerald, Anne Chain, Sebastian Polak, Christopher P. Regan, Pierre Morissette, Patrick Fanelli, Jeffrey Travis, Blanca Rodriguez
المصدر: Toxicology and Applied Pharmacology
مصطلحات موضوعية: 0301 basic medicine, ICH, The International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use, TN, True Negative, PPV, Positive Predictive Value, Pharmacology, TdP, Torsade de Pointes, Toxicology, Membrane Potentials, 0302 clinical medicine, HTS, High Throughput Screening, QTcVdW, Van de Water's Heart Rate QT-corrected Interval, In Silico modeling, Medicine, Translational PKPD modeling, NCEs, New Chemical Entities, CTD90, Ca2+-Transient Duration at 90% repolarization, education.field_of_study, Anesthetized Cardiovascular Guinea Pig, HR, Heart Rate, PNV, Predictive Negative Value, Safety pharmacology, ECG, Electrocardiogram, FIH, First in Human, IKr, rapidly-activating delayed rectifier potassium current, AP, Action Potential, QTc, Heart Rate corrected QT Interval, PX, PatchXpress®, 030220 oncology & carcinogenesis, Electrophysiologic Techniques, Cardiac, FP, False Positive, LVP, Left Ventricular Pressure, Anti-Arrhythmia Agents, In silico, Population, Guinea Pigs, QT interval, Models, Biological, Article, Ventricular action potential, Cell Line, CVGP, Cardiovascular Anesthetized Guinea Pig, GP, Guinea Pig, 03 medical and health sciences, hERG, Human Ether-a-go-go Related Gene, Pharmacokinetics, In vivo, Animals, Humans, Computer Simulation, education, QT corrected interval, BP, Blood Pressure, business.industry, M5P, M5 trees automated pruning model, tPKPD, thranslational pharmacokinetic/pharmacodynamic, FLIPR, Fluorescent Imaging Plate Reader, Arrhythmias, Cardiac, ORd, O'Hara Rudy model, Electrophysiological Phenomena, 030104 developmental biology, HEK293 Cells, Models, Chemical, Pharmacodynamics, Torsade de Pointes, EMw, Electromechanical window, FN, False Negative, TP, True Positive, Calcium, Calcium Channels, LOO, Leave-One-Out, business, APD90, Action Potential Duration at 90% repolarization
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2
المؤلفون: Sebastian Polak, Blanca Rodriguez, Elisa Passini, Patrick Fanelli, Jin Zhai, Kevin Fitzgerald, Jeffrey Travis, Pierre Morissette, Anne S. Y. Chain, Frederick Sannajust, Christopher P. Regan
المصدر: Journal of Pharmacological and Toxicological Methods. 105:106804
مصطلحات موضوعية: Pharmacology, Guinea pig, medicine.medical_specialty, Arrhythmic risk, business.industry, Internal medicine, In silico, Qtc interval prolongation, Cardiology, Medicine, Toxicology, business
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3
المؤلفون: Kevin Fitzgerald, Hillary Regan, Patrick Fanelli, Jeffrey Travis, Pierre Morissette, Pamela Gerenser, Sylvain Bernasconi, Christopher P. Regan, Frederick Sannajust
المصدر: Journal of Pharmacological and Toxicological Methods. 75:52-61
مصطلحات موضوعية: Male, Xylazine, Guinea Pigs, hERG, Toxicology, QT interval, Electrocardiography, Heart Rate, Phenethylamines, Heart rate, medicine, Animals, Repolarization, Ivabradine, Ketamine, Ephedrine, Pharmacology, Sulfonamides, biology, business.industry, Sotalol, Benzazepines, Long QT Syndrome, Anesthesia, Models, Animal, biology.protein, business, medicine.drug
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4
المؤلفون: Francesca, Mullins, Shawn, Ott, Nakia, Mister, Jeffrey, Travis
المصدر: The journal of extra-corporeal technology. 50(2)
مصطلحات موضوعية: Cardiopulmonary Bypass, Exchange Transfusion, Whole Blood, Humans, Female, Hemoglobin SC Disease, Case Reports, Coronary Artery Bypass, Middle Aged
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::83f7bc6afb36ac54b6d63fbc42ca065f
https://pubmed.ncbi.nlm.nih.gov/29921991 -
5
المؤلفون: Andrew Hardyniec, Charles DeVore, Jeffrey Travis
المصدر: Structures Congress 2017.
مصطلحات موضوعية: Rack, Engineering, business.industry, Structural engineering, business, Period (music)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7b6ece535c7a75cf67ee853289af7f75
https://doi.org/10.1061/9780784480410.065 -
6
المؤلفون: Bharathi Balasubramanian, Pamela Gerenser, Frederick Sannajust, Blanca Rodriguez, Patrick Fanelli, Alfonso Bueno-Orovio, Elisa Passini, Pierre Morissette, Jeffrey Travis, Christopher P. Regan
المصدر: Journal of Pharmacological and Toxicological Methods. 93:144-145
مصطلحات موضوعية: Pharmacology, Arrhythmic risk, Chemistry, In silico, 02 engineering and technology, Toxicology, 01 natural sciences, 010305 fluids & plasmas, Guinea pig, Vanoxerine, In vivo, 0103 physical sciences, 0202 electrical engineering, electronic engineering, information engineering, medicine, 020201 artificial intelligence & image processing, Ion channel, medicine.drug
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7
المؤلفون: Jin Zhai, Christopher P. Regan, Elisa Passini, Frederick Sannajust, Pierre Morissette, Patrick Fanelli, Blanca Rodriguez, Jeffrey Travis, Alfonso Bueno-Orovio, John Imredy, Spencer J. Dech
المصدر: Journal of Pharmacological and Toxicological Methods. 99:106595
مصطلحات موضوعية: Pharmacology, Arrhythmic risk, business.industry, In silico, Medicine, Computational biology, Toxicology, business, In vitro, Ion channel
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8كتاب إلكتروني
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9
المؤلفون: Haoyu Zeng, Frederick Sannajust, John Imredy, Christopher P. Regan, Jeffrey Travis, Pierre Morissette, Spencer J. Dech, Armando Lagrutta, Bharathi Balasubramanian
المصدر: Journal of Pharmacological and Toxicological Methods. 88:237
مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, business.industry, Hepatitis C virus, Drug interaction, Toxicology, medicine.disease_cause, Amiodarone, In vitro, chemistry, medicine, Nucleotide, business, medicine.drug
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10
المؤلفون: Pamela Gerenser, Christopher P. Regan, Spencer J. Dech, Anne S. Y. Chain, Pierre Morissette, Patrick Fanelli, Jeffrey Travis, Frederick Sannajust
المصدر: Journal of Pharmacological and Toxicological Methods. 88:208
مصطلحات موضوعية: Pharmacology, Drug development, Arrhythmic risk, business.industry, In silico, Medicine, Toxicology, Bioinformatics, business, Comparative evaluation