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المؤلفون: Keith B. Elkon, Mariana J. Kaplan, Luz P. Blanco, Jeffrey A. Ledbetter, Monica M. Purmalek, Suk See De Ravin, Christian Lood, Carolyne K. Smith, Harry L. Malech, Carmelo Carmona-Rivera
المصدر: Nature medicine
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Mitochondrial ROS, Mitochondrial DNA, Neutrophils, Antigen-Antibody Complex, In Vitro Techniques, Biology, Mitochondrion, Granulomatous Disease, Chronic, Kidney, Real-Time Polymerase Chain Reaction, medicine.disease_cause, DNA, Mitochondrial, Extracellular Traps, Article, General Biochemistry, Genetics and Molecular Biology, Autoimmunity, Proinflammatory cytokine, Jurkat Cells, Mice, 03 medical and health sciences, medicine, Animals, Humans, Immunoprecipitation, Lupus Erythematosus, Systemic, Peroxidase, Lupus erythematosus, Systemic lupus erythematosus, NADPH Oxidases, General Medicine, Neutrophil extracellular traps, medicine.disease, Molecular biology, Mitochondria, 030104 developmental biology, Microscopy, Fluorescence, Ribonucleoproteins, Interferon Type I, Female, Reactive Oxygen Species, Oxidation-Reduction
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المؤلفون: Christian Lood, Jeffrey A. Ledbetter, Keith B. Elkon, Sabine Arve
المصدر: Poster Session.
مصطلحات موضوعية: NADPH oxidase, biology, Phagocytosis, Complement C5a, Inflammation, Neutrophil extracellular traps, Immune complex, Complement system, Cell biology, Immune system, Immunology, biology.protein, medicine, medicine.symptom
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::28f80b322a637eafef0c3011b984dbd9
https://doi.org/10.1136/lupus-2017-000215.340 -
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المؤلفون: Randolph J, Noelle, Meenakshi, Roy, David M, Shepherd, Ivan, Stamenkovico, Jeffrey A, Ledbetter, Alejandro, Aruffo
المصدر: Journal of immunology (Baltimore, Md. : 1950). 197(11)
مصطلحات موضوعية: B-Lymphocytes, Animals, Humans, T-Lymphocytes, Helper-Inducer, CD40 Antigens, History, 20th Century, Lymphocyte Activation, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b882b0c9f7d81aa81e7ebb3e3f2315e6
https://pubmed.ncbi.nlm.nih.gov/27864549 -
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المؤلفون: Keith B. Elkon, Christian Lood, Sabine Arve, Jeffrey A. Ledbetter
المصدر: The Journal of Experimental Medicine
مصطلحات موضوعية: 0301 basic medicine, Neutrophils, Phagocytosis, Immunology, Blotting, Western, Complement C5a, Inflammation, Antigen-Antibody Complex, Extracellular Traps, Monocytes, Article, 03 medical and health sciences, Immune system, medicine, Immunology and Allergy, Humans, Lupus Erythematosus, Systemic, Complement Activation, Cells, Cultured, Research Articles, Lupus erythematosus, Chemistry, Receptors, IgG, TLR7, Dendritic Cells, biochemical phenomena, metabolism, and nutrition, medicine.disease, Flow Cytometry, Immune complex, Complement system, 030104 developmental biology, Toll-Like Receptor 7, Toll-Like Receptor 8, medicine.symptom
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6db948f05b01527bf586711f8470c78
https://pubmed.ncbi.nlm.nih.gov/28606989 -
5Increased Ribonuclease Expression Reduces Inflammation and Prolongs Survival in TLR7 Transgenic Mice
المؤلفون: Jessica A. Hamerman, Jeffrey A. Ledbetter, Nalini Agrawal, Thomas H. Teal, Denny Liggitt, Charles E. Alpers, Matthew B. Buechler, Lena Tanaka, Kelly L. Hudkins, Xizhang Sun, Keith B. Elkon, Alice E. Wiedeman, Silvia Bolland
المصدر: The Journal of Immunology. 190:2536-2543
مصطلحات موضوعية: Male, Genetically modified mouse, medicine.medical_specialty, RNase P, Transgene, Immunology, Down-Regulation, Mice, Transgenic, Inflammation, Biology, Article, Hepatitis, Pathogenesis, Mice, Internal medicine, medicine, Animals, Humans, Lupus Erythematosus, Systemic, Immunology and Allergy, Cells, Cultured, Embryonic Stem Cells, Mice, Inbred C3H, Membrane Glycoproteins, Autoantibody, virus diseases, Glomerulonephritis, Ribonuclease, Pancreatic, TLR7, medicine.disease, Survival Analysis, Molecular biology, Up-Regulation, Mice, Inbred C57BL, Endocrinology, Toll-Like Receptor 7, Cattle, medicine.symptom, Spleen
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28023e6f1ab801f1b07e90265f621e57
https://doi.org/10.4049/jimmunol.1202689 -
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المؤلفون: Jeffrey A. Ledbetter, Jay W. Chaplin, Shinji Kasahara, Edward A. Clark
المصدر: The Journal of Immunology. 187:4199-4209
مصطلحات موضوعية: T-Lymphocytes, T cell, Immunology, Naive B cell, Immunoglobulins, Enzyme-Linked Immunosorbent Assay, Cell Separation, Lymphocyte Activation, Article, Mice, Antigens, CD, Marginal zone B-cell, medicine, Animals, Immunology and Allergy, Follicular B cell, B cell, Cell Proliferation, Mice, Knockout, CD86, B-Lymphocytes, CD40, biology, Cell Differentiation, hemic and immune systems, Flow Cytometry, Molecular biology, Mice, Inbred C57BL, medicine.anatomical_structure, Antibody Formation, Myeloid Differentiation Factor 88, biology.protein, CD80
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea72a0857715a6036ba856df3472d82
https://doi.org/10.4049/jimmunol.1100198 -
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مصطلحات موضوعية: Cellular immunity, medicine.drug_class, Lymphocyte, T lymphocyte, Biology, Monoclonal antibody, Natural killer cell, medicine.anatomical_structure, Antigen, Monoclonal, Immunology, medicine, biology.protein, Antibody
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a3bcbc4933671b5ca2b4e5b3dcf307ae
https://doi.org/10.1159/000414681 -
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المؤلفون: Phil Habecker, Lisa McNeill, Che Leung Law, Martha Hayden-Ledbetter, Sonya Buckwalter, Barbara A. Thorne, Dua Raj, Jeffrey A. Ledbetter, Hieu Nguyen
المصدر: International Immunology. 14:389-400
مصطلحات موضوعية: CD3 Complex, Protein Conformation, Recombinant Fusion Proteins, CD3, Immunology, Antibody Affinity, Epitopes, T-Lymphocyte, Epitope, law.invention, Protein structure, law, Humans, Immunology and Allergy, Cells, Cultured, Models, Genetic, biology, T-cell receptor, Immunoglobulin Fc Fragments, General Medicine, Fusion protein, Molecular biology, Biochemistry, Receptor-CD3 Complex, Antigen, T-Cell, Immunoglobulin G, biology.protein, Recombinant DNA, Muromonab-CD3
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41fa848e5c36449a6ef44d7954afb4b
https://doi.org/10.1093/intimm/14.4.389 -
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المؤلفون: Jeffrey A. Ledbetter, Martha Hayden-Ledbetter, Amber Dahlin, Ingegerd Hellström, Karl Erik Hellström, Nathalie Scholler
المصدر: The Journal of Immunology. 168:2599-2602
مصطلحات موضوعية: Cytotoxicity, Immunologic, CD3 Complex, Recombinant Fusion Proteins, T-Lymphocytes, T cell, Immunology, Immunoglobulins, chemical and pharmacologic phenomena, CD8-Positive T-Lymphocytes, Biology, Lymphocyte Activation, Mice, Interleukin 21, Antigens, CD, Tumor Cells, Cultured, medicine, Animals, Humans, Immunology and Allergy, Cytotoxic T cell, IL-2 receptor, Antigen-presenting cell, Cell Line, Transformed, Interleukin 3, B-Lymphocytes, Immunity, Cellular, Mice, Inbred C3H, Membrane Glycoproteins, Antibodies, Monoclonal, hemic and immune systems, Natural killer T cell, Cell biology, medicine.anatomical_structure, Solubility, Mice, Inbred DBA, Interleukin 12, Female, Lymphocyte Culture Test, Mixed, K562 Cells, Cell Division, Immunosuppressive Agents, Injections, Intraperitoneal, Neoplasm Transplantation
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834cca8a9e0f95f287efd68acbd9fecc
https://doi.org/10.4049/jimmunol.168.6.2599 -
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المؤلفون: Andre R. Simon, Jeffrey A. Ledbetter, L. LeFlufy, Mick Bailey, Zhe-Sheng Chen, Karin Haverson, Christopher R. Stokes, G. Banfield, Enoc Hollemweguer
المصدر: Veterinary Immunology and Immunopathology. 80:175-186
مصطلحات موضوعية: Swine, medicine.drug_class, CD14, education, Immunology, CD11c, Cross Reactions, Monoclonal antibody, medicine.disease_cause, Cross-reactivity, Monocytes, Species Specificity, Antigen, Antibody Specificity, Antigens, CD, Leukocytes, medicine, Animals, Humans, Lymphocytes, CD40, General Veterinary, biology, CD47, Antibodies, Monoclonal, Virology, biology.protein, Antibody, Granulocytes