المؤلفون: Morgensztern D; Washington University in St. Louis, St. Louis, MO, United States., Ready N; Duke Medical Center, Durham, NC, United States., Johnson ML; Sarah Cannon Research Instutite, Nashville, TN, United States., Dowlati A; University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States., Choudhury N; Memorial Sloan Kettering Cancer Center, New York, NY, United States., Carbone DP; The Ohio State University Medical Center, Columbus, OH, United States., Schaefer E; Highlands Oncology Group, Fayetteville, AR, United States., Arnold SM; University of Kentucky, Lexington, KY, United States., Puri S; Huntsman Cancer Institute, Salt Lake City, Utah, United States., Piotrowska Z; Massachusetts General Hospital, Boston, Massachusetts, United States., Hegde A; University of Alabama at Birmingham, Birmingham, Alabama, United States., Chiang AC; Yale University, New Haven, CT, United States., Iams W; Northwestern Memorial Hospital, Nashville, TN, United States., Tolcher A; South Texas Accelerated Research Therapeutics, San Antonio, TX, United States., Nosaki K; National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Kozuki T; National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan., Li T; University of California, Davis, Sacramento, United States., Santana-Davila R; Fred Hutchinson/University of Washington/Seattle Children's Cancer Consortium, Seattle, United States., Akamatsu H; Wakayama Medical University, Wakayama, Japan., Murakami H; Shizuoka Cancer Center, Sunto-gun, Shizuoka, Japan., Yokouchi H; NHO Hokkaido Cancer Center, Sapporo, Japan., Wang S; AbbVie Inc., North Chicago, Illinois, United States., Zha J; AbbVie, North Chicago, Illinois, United States., Li R; AbbVie Inc., North Chicago, Illinois, United States., Robinson RR; AbbVie Inc., South San Francisco, CA, United States., Hingorani P; AbbVie (United States), United States., Jeng EE; AbbVie (United States), North Chicago, Illinois, United States., Furqan M; University of Iowa, Iowa city, Iowa, United States.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Sep 17. Date of Electronic Publication: 2024 Sep 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

المؤلفون: Cohen A; University of California San Francisco, Department of Microbiology and Immunology, San Francisco, California, United States of America., Jeng EE; Stanford University, Department of Genetics, Palo Alto, California, United States of America., Voorhies M; University of California San Francisco, Department of Microbiology and Immunology, San Francisco, California, United States of America., Symington J; University of California San Francisco, Department of Microbiology and Immunology, San Francisco, California, United States of America., Ali N; University of California San Francisco, Department of Microbiology and Immunology, San Francisco, California, United States of America., Rodriguez RA; University of California San Francisco, Department of Microbiology and Immunology, San Francisco, California, United States of America., Bassik MC; Stanford University, Department of Genetics, Palo Alto, California, United States of America., Sil A; University of California San Francisco, Department of Microbiology and Immunology, San Francisco, California, United States of America.

المصدر: PLoS pathogens [PLoS Pathog] 2022 Sep 29; Vol. 18 (9), pp. e1010237. Date of Electronic Publication: 2022 Sep 29 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

مواضيع طبية MeSH: Actins* , Histoplasmosis*, Receptors, Complement/metabolism ; Macrophages/metabolism ; Histoplasma/genetics ; Histoplasma/metabolism ; Receptors, G-Protein-Coupled/metabolism ; Peptide Fragments

المؤلفون: Chaikovsky AC; Department of Pediatrics, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Li C; Department of Biology, Stanford University, Stanford, CA, USA., Jeng EE; Department of Genetics, Stanford University, Stanford, CA, USA., Loebell S; Department of Pediatrics, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Lee MC; Department of Pediatrics, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Murray CW; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Pathology, Stanford University, Stanford, CA, USA., Cheng R; Department of Biology, Stanford University, Stanford, CA, USA., Demeter J; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA., Swaney DL; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Gladstone Insitutes, San Francisco, CA, USA., Chen SH; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Gladstone Insitutes, San Francisco, CA, USA., Newton BW; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Gladstone Insitutes, San Francisco, CA, USA., Johnson JR; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Gladstone Insitutes, San Francisco, CA, USA., Drainas AP; Department of Pediatrics, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Shue YT; Department of Pediatrics, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Seoane JA; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Medicine, Stanford University, Stanford, CA, USA., Srinivasan P; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Medicine, Stanford University, Stanford, CA, USA., He A; Department of Pediatrics, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Yoshida A; Department of Biochemistry, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.; Case Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, OH, USA., Hipkins SQ; Department of Pediatrics, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., McCrea E; Department of Pediatrics, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Poltorack CD; Department of Pediatrics, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Krogan NJ; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Gladstone Insitutes, San Francisco, CA, USA., Diehl JA; Department of Biochemistry, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.; Case Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, OH, USA., Kong C; Department of Pathology, Stanford University, Stanford, CA, USA., Jackson PK; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA., Curtis C; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Medicine, Stanford University, Stanford, CA, USA., Petrov DA; Department of Biology, Stanford University, Stanford, CA, USA., Bassik MC; Department of Genetics, Stanford University, Stanford, CA, USA., Winslow MM; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Pathology, Stanford University, Stanford, CA, USA., Sage J; Department of Pediatrics, Stanford University, Stanford, CA, USA. julsage@stanford.edu.; Department of Genetics, Stanford University, Stanford, CA, USA. julsage@stanford.edu.

المصدر: Nature [Nature] 2021 Apr; Vol. 592 (7856), pp. 794-798. Date of Electronic Publication: 2021 Apr 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing/*metabolism , Cyclin D/*metabolism, Adenocarcinoma of Lung/genetics ; Animals ; Cell Division ; Cyclin-Dependent Kinase 4/antagonists & inhibitors ; Cyclin-Dependent Kinase 4/metabolism ; Cyclin-Dependent Kinase 6/antagonists & inhibitors ; Cyclin-Dependent Kinase 6/metabolism ; Genes, Tumor Suppressor ; Humans ; Lung Neoplasms/genetics ; Mice ; Piperazines/pharmacology ; Pyridines/pharmacology ; U937 Cells ; Ubiquitination

المؤلفون: Kelly MR; Baxter Laboratory, Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, California.; Program in Cancer Biology, Stanford University School of Medicine, Stanford, California., Kostyrko K; Division of Hematology and Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, California., Han K; Department of Genetics, Stanford University School of Medicine, Stanford, California., Mooney NA; Baxter Laboratory, Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, California., Jeng EE; Department of Genetics, Stanford University School of Medicine, Stanford, California., Spees K; Department of Genetics, Stanford University School of Medicine, Stanford, California., Dinh PT; Division of Hematology and Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, California., Abbott KL; Baxter Laboratory, Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, California., Gwinn DM; Division of Hematology and Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, California., Sweet-Cordero EA; Division of Hematology and Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, California. pjackson@stanford.edu bassik@stanford.edu Alejandro.Sweet-Cordero@ucsf.edu., Bassik MC; Department of Genetics, Stanford University School of Medicine, Stanford, California. pjackson@stanford.edu bassik@stanford.edu Alejandro.Sweet-Cordero@ucsf.edu.; Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford University, Stanford, California., Jackson PK; Baxter Laboratory, Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, California. pjackson@stanford.edu bassik@stanford.edu Alejandro.Sweet-Cordero@ucsf.edu.; Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford University, Stanford, California.; Department of Pathology, Stanford University School of Medicine, Stanford, California.

المصدر: Cancer discovery [Cancer Discov] 2020 Dec; Vol. 10 (12), pp. 1950-1967. Date of Electronic Publication: 2020 Jul 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Lung Neoplasms/*genetics , Proteomics/*methods , ras Proteins/*genetics, Humans

المؤلفون: Jeng EE; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Program in Cancer Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Bhadkamkar V; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA., Ibe NU; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA., Gause H; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA., Jiang L; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Chan J; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Jian R; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Jimenez-Morales D; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; The J. David Gladstone Institutes, San Francisco, CA, USA., Stevenson E; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; The J. David Gladstone Institutes, San Francisco, CA, USA., Krogan NJ; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; The J. David Gladstone Institutes, San Francisco, CA, USA., Swaney DL; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; The J. David Gladstone Institutes, San Francisco, CA, USA., Snyder MP; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Mukherjee S; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: shaeri.mukherjee@ucsf.edu., Bassik MC; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: bassik@stanford.edu.

المصدر: Cell host & microbe [Cell Host Microbe] 2019 Oct 09; Vol. 26 (4), pp. 551-563.e6. Date of Electronic Publication: 2019 Sep 17.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101302316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1934-6069 (Electronic) Linking ISSN: 19313128 NLM ISO Abbreviation: Cell Host Microbe Subsets: MEDLINE

مواضيع طبية MeSH: Legionella pneumophila/*pathogenicity , Legionnaires' Disease/*pathology , Phagocytosis/*immunology , Proteins/*genetics , Vacuoles/*microbiology, Animals ; Bacterial Proteins/metabolism ; Cell Line ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; Endoplasmic Reticulum/metabolism ; Guanine Nucleotide Exchange Factors/genetics ; Guanine Nucleotide Exchange Factors/metabolism ; HEK293 Cells ; HeLa Cells ; Humans ; Legionella pneumophila/genetics ; Macrophages/metabolism ; Macrophages/microbiology ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; RAW 264.7 Cells ; U937 Cells ; Virulence Factors/genetics ; rab GTP-Binding Proteins/genetics ; rab GTP-Binding Proteins/metabolism

المؤلفون: Duque-Afonso J; Department of Pathology, Stanford University School of Medicine, Stanford, California.; Department of Hematology and Oncology, University Medical Center Freiburg, Freiburg, Germany., Lin CH; Department of Pathology, Stanford University School of Medicine, Stanford, California., Han K; Department of Genetics, Stanford University School of Medicine, Stanford, California., Morgens DW; Department of Genetics, Stanford University School of Medicine, Stanford, California., Jeng EE; Department of Genetics, Stanford University School of Medicine, Stanford, California., Weng Z; Department of Pathology, Stanford University School of Medicine, Stanford, California.; Stanford Center for Genomics and Personalized Medicine, Stanford, California., Jeong J; Department of Pathology, Stanford University School of Medicine, Stanford, California., Wong SHK; Department of Pathology, Stanford University School of Medicine, Stanford, California., Zhu L; Department of Pathology, Stanford University School of Medicine, Stanford, California., Wei MC; Department of Pediatrics, Stanford University School of Medicine, Stanford, California., Chae HD; Department of Pediatrics, Stanford University School of Medicine, Stanford, California., Schrappe M; Department of Pediatrics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Cario G; Department of Pediatrics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Duyster J; Department of Hematology and Oncology, University Medical Center Freiburg, Freiburg, Germany., Xiao X; Department of Physiology and Pharmacology, Oregon Health and Science University, Portland, Oregon., Sakamoto KM; Department of Pediatrics, Stanford University School of Medicine, Stanford, California., Bassik MC; Department of Genetics, Stanford University School of Medicine, Stanford, California., Cleary ML; Department of Pathology, Stanford University School of Medicine, Stanford, California. mcleary@stanford.edu.

المصدر: Cancer research [Cancer Res] 2018 Nov 15; Vol. 78 (22), pp. 6497-6508. Date of Electronic Publication: 2018 Sep 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm*, Antineoplastic Agents/*pharmacology , CREB-Binding Protein/*metabolism , Dasatinib/*pharmacology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy , Protein Kinase Inhibitors/*pharmacology, Apoptosis ; Cell Cycle ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Gene Expression Regulation, Leukemic ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy ; Protein Binding ; Protein Domains ; Pyrimidines/pharmacology ; RNA, Small Interfering/metabolism ; Signal Transduction ; Transcription, Genetic ; beta Catenin/genetics

المؤلفون: Morgens DW; Department of Genetics, Stanford University, Stanford, California 94305, USA., Wainberg M; Department of Computer Science, Stanford University, Stanford, California 94305, USA., Boyle EA; Department of Genetics, Stanford University, Stanford, California 94305, USA., Ursu O; Department of Genetics, Stanford University, Stanford, California 94305, USA., Araya CL; Department of Genetics, Stanford University, Stanford, California 94305, USA., Tsui CK; Department of Genetics, Stanford University, Stanford, California 94305, USA., Haney MS; Department of Genetics, Stanford University, Stanford, California 94305, USA., Hess GT; Department of Genetics, Stanford University, Stanford, California 94305, USA., Han K; Department of Genetics, Stanford University, Stanford, California 94305, USA., Jeng EE; Department of Genetics, Stanford University, Stanford, California 94305, USA.; Program in Cancer Biology, Stanford University, Stanford, California 94305, USA., Li A; Department of Genetics, Stanford University, Stanford, California 94305, USA., Snyder MP; Department of Genetics, Stanford University, Stanford, California 94305, USA., Greenleaf WJ; Department of Genetics, Stanford University, Stanford, California 94305, USA., Kundaje A; Department of Genetics, Stanford University, Stanford, California 94305, USA.; Department of Computer Science, Stanford University, Stanford, California 94305, USA., Bassik MC; Department of Genetics, Stanford University, Stanford, California 94305, USA.; Stanford University Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford, California 94305, USA.

المصدر: Nature communications [Nat Commun] 2017 May 05; Vol. 8, pp. 15178. Date of Electronic Publication: 2017 May 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Genomic Library*, CRISPR-Cas Systems/*genetics , Gene Targeting/*methods , High-Throughput Screening Assays/*methods , RNA, Guide, CRISPR-Cas Systems/*genetics, Cell Line ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; DNA Damage/genetics ; Humans ; Polysaccharides/biosynthesis ; RNA Interference ; Ricin/toxicity

المؤلفون: Han K; Department of Genetics, Stanford University, Stanford, California, USA., Jeng EE; Department of Genetics, Stanford University, Stanford, California, USA.; Program in Cancer Biology, Stanford University, Stanford, California, USA., Hess GT; Department of Genetics, Stanford University, Stanford, California, USA., Morgens DW; Department of Genetics, Stanford University, Stanford, California, USA., Li A; Department of Genetics, Stanford University, Stanford, California, USA., Bassik MC; Department of Genetics, Stanford University, Stanford, California, USA.; Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford University, Stanford, California, USA.

المصدر: Nature biotechnology [Nat Biotechnol] 2017 May; Vol. 35 (5), pp. 463-474. Date of Electronic Publication: 2017 Mar 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Combined Chemotherapy Protocols/*administration & dosage , Clustered Regularly Interspaced Short Palindromic Repeats/*genetics , Drug Screening Assays, Antitumor/*methods , Neoplasm Proteins/*genetics , Neoplasms, Experimental/*drug therapy , Neoplasms, Experimental/*genetics, Drug Synergism ; Humans ; K562 Cells