المؤلفون: Sarah Cherkaoui, Stephan Durot, Jenna Bradley, Susan Critchlow, Sebastien Dubuis, Mauro Miguel Masiero, Rebekka Wegmann, Berend Snijder, Alaa Othman, Claus Bendtsen, Nicola Zamboni

المصدر: Molecular Systems Biology, Vol 18, Iss 11, Pp n/a-n/a (2022)

مصطلحات موضوعية: cancer metabolism, cell lines, metabolomics, metabolic flux, omics, Biology (General), QH301-705.5, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1744-4292

URL الوصول: https://doaj.org/article/f08af028dfe24fef9f1b71841af181be

المؤلفون: David Shorthouse, Jenna Bradley, Susan E Critchlow, Claus Bendtsen, Benjamin A Hall

المصدر: Molecular Systems Biology, Vol 18, Iss 11, Pp n/a-n/a (2022)

مصطلحات موضوعية: cancer, heterogeneity, metabolomics, mutation, Biology (General), QH301-705.5, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1744-4292

URL الوصول: https://doaj.org/article/0313cb9805bf4769a4632f9cd173f143

المؤلفون: Anders Lundin, Michelle J. Porritt, Himjyot Jaiswal, Frank Seeliger, Camilla Johansson, Abdel Wahad Bidar, Lukas Badertscher, Sandra Wimberger, Emma J. Davies, Elizabeth Hardaker, Carla P. Martins, Emily James, Therese Admyre, Amir Taheri-Ghahfarokhi, Jenna Bradley, Anna Schantz, Babak Alaeimahabadi, Maryam Clausen, Xiufeng Xu, Lorenz M. Mayr, Roberto Nitsch, Mohammad Bohlooly-Y, Simon T. Barry, Marcello Maresca

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/8d05a4aa843b419591409ca746b331db

المؤلفون: Adedolapo Adebakin, Jenna Bradley, Sarah Gümüsgöz, Elizabeth J Waters, Catherine B Lawrence

المصدر: PLoS ONE, Vol 7, Iss 10, p e45179 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3464300?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/3efa09a55ff444849276fc6846b07201

المؤلفون: Jenna Bradley, Claus Bendtsen, David Shorthouse, Susan E. Critchlow, Benjamin A. Hall

المصدر: Molecular systems biology. 18(11)

مصطلحات موضوعية: Drug, media_common.quotation_subject, Computational biology, Biology, General Biochemistry, Genetics and Molecular Biology, Mass Spectrometry, Cell Line, Neoplasms, Gene expression, medicine, Humans, Metabolomics, Gene, media_common, General Immunology and Microbiology, Applied Mathematics, Cancer, medicine.disease, Phenotype, Metabolic pathway, Computational Theory and Mathematics, Metabolic control analysis, Cancer cell lines, General Agricultural and Biological Sciences, Metabolic Networks and Pathways, Information Systems

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a08bd0cb17c793ed4ff000a86829f0
https://pubmed.ncbi.nlm.nih.gov/36321551

المؤلفون: Frank Seeliger, Carla P. Martins, Emily James, Sandra Wimberger, Camilla Johansson, Mohammad Bohlooly-Y, Emma J. Davies, Maryam Clausen, Lukas Badertscher, Michelle J. Porritt, Simon T. Barry, Xiufeng Xu, Anna Schantz, Roberto Nitsch, Amir Taheri-Ghahfarokhi, Marcello Maresca, Himjyot Jaiswal, Elizabeth Hardaker, Jenna Bradley, Babak Alaeimahabadi, Lorenz M. Mayr, Abdel Wahad Bidar, Therese Admyre, Anders Lundin

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Male, Lung Neoplasms, Somatic cell, Molecular biology, General Physics and Astronomy, Gene Expression, Mice, 0302 clinical medicine, Genome editing, CRISPR-Associated Protein 9, Carcinoma, Non-Small-Cell Lung, Drug Discovery, Transgenes, lcsh:Science, Cancer, Doxycycline, Gene Editing, Recombination, Genetic, Multidisciplinary, 3. Good health, Gene Expression Regulation, Neoplastic, Drug development, 030220 oncology & carcinogenesis, Female, medicine.drug, RNA, Guide, Kinetoplastida, Transcriptional Activation, Transgene, Science, Genetic Vectors, Antineoplastic Agents, Mice, Transgenic, Computational biology, Biology, Transfection, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, In vivo, Cell Line, Tumor, medicine, Genetics, Animals, Humans, Cas9, HEK 293 cells, Reproducibility of Results, General Chemistry, High-Throughput Screening Assays, 030104 developmental biology, HEK293 Cells, lcsh:Q, CRISPR-Cas Systems, Drug Screening Assays, Antitumor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be35d27a5ad372f5e73cee5b16a0b91e
http://link.springer.com/article/10.1038/s41467-020-18548-9

المؤلفون: Sarah Cherkaoui, Stephan Durot, Jenna Bradley, Susan Critchlow, Sebastien Dubuis, Mauro Miguel Masiero, Rebekka Wegmann, Berend Snijder, Alaa Othman, Claus Bendtsen, Nicola Zamboni

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::17e1406a129685a606786f83a1e08a2d
https://doi.org/10.1101/2021.11.02.466992

المؤلفون: Jenna Bradley, Mike Firth, Jian-Ping Yang, James Pilling, Jonathan D. Chesnut, Jan Wildenhain, David R. Piper, Mathew Leveridge, Patrick J. O'Shea, Chetana M. Revankar, Beverley Isherwood

المصدر: SLAS Discovery. 25:618-633

مصطلحات موضوعية: Computational biology, Biology, Biochemistry, beta-Lactamases, Analytical Chemistry, 03 medical and health sciences, 0302 clinical medicine, Genes, Reporter, RNA interference, Reference genes, Humans, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Genomic library, Gene Library, 030304 developmental biology, 0303 health sciences, Reporter gene, Genome, Human, Tumor Necrosis Factor-alpha, Cas9, Phosphotransferases, NF-kappa B, Amplicon, High-Throughput Screening Assays, Molecular Medicine, CRISPR-Cas Systems, Functional genomics, 030217 neurology & neurosurgery, RNA, Guide, Kinetoplastida, Signal Transduction, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa13617615321cd50a6cb64e3cb3a59
https://doi.org/10.1177/2472555220926160

المؤلفون: Amir Taheri-Ghahfarokhi, Alaeimahabadi B, Anders Lundin, Frank Seeliger, Lukas Badertscher, Lorenz M. Mayr, Carla P. Martins, Xiufeng Xu, Camilla Johansson, Therese Admyre, Mohammad Bohlooly-Y, Emma J. Davies, Simon T. Barry, Abdel Wahad Bidar, Marcello Maresca, Anna Schantz, Maryam Clausen, Michelle J. Porritt, Elizabeth Hardaker, Jenna Bradley, Roberto Nitsch, Himjyot Jaiswal

مصطلحات موضوعية: Doxycycline, Genome editing, Drug development, Somatic cell, In vivo, Cas9, Drug discovery, Transgene, medicine, Computational biology, Biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87692a8b8c939432739b4366cbb0f0a7
https://doi.org/10.1101/2020.04.06.028803

المؤلفون: Iain Simpson, Joanna Boros, Jonathan Tart, Thorsten Nowak, Keeva McClelland, Anne U. Goeppert, Jenna Bradley, Krzysztofa Ewa Odrzywol, Jarrod Walsh, Jonathan D. Wrigley, Lindsey Leach, Andrea Valentine, Jonathan Renshaw, Helen Plant, Richard A. Ward, Gareth M. Davies, Tim Harrison, Gerald Gavory, David M. Andrews, Ewelina Rozycka, Marian Preston

المصدر: Wrigley, J D, Gavory, G, Simpson, I, Preston, M, Plant, H, Bradley, J, Goeppert, A U, Rozycka, E, Davies, G, Walsh, J, Valentine, A, McClelland, K, Odrzywol, K E, Renshaw, J, Boros, J, Tart, J, Leach, L, Nowak, T, Ward, R A, Harrison, T & Andrews, D M 2017, ' Identification and Characterization of Dual Inhibitors of the USP25/ 28 Deubiquitinating Enzyme Subfamily ', ACS Chemical Biology . https://doi.org/10.1021/acschembio.7b00334

مصطلحات موضوعية: 0301 basic medicine, Ubiquitin-Specific Proteases, Subfamily, Antineoplastic Agents, Computational biology, Biology, Biochemistry, Deubiquitinating enzyme, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Humans, Enzyme Inhibitors, Cell Proliferation, Drug discovery, Target engagement, General Medicine, DUAL (cognitive architecture), HCT116 Cells, 030104 developmental biology, Proteasome, biology.protein, Molecular Medicine, Identification (biology), Ubiquitin Thiolesterase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f13e61e1f295cc5b9b607aee18a67e6
https://pubmed.ncbi.nlm.nih.gov/29131570