المؤلفون: Daniel J. Lenihan, MD, Sarah A. Anderson, ACNP, Carrie Geisberg Lenneman, MD, Evan Brittain, MD, MSCI, James A.S. Muldowney, III, MD, Lisa Mendes, MD, Ping Z. Zhao, PhD, Jennifer Iaci, MS, Stephen Frohwein, MD, Ronald Zolty, MD, PhD, Andrew Eisen, MD, PhD, Douglas B. Sawyer, MD, PhD, Anthony O. Caggiano, MD, PhD

المصدر: JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 576-586 (2016)

مصطلحات موضوعية: cardiac repair, growth factor, neuregulin, systolic dysfunction, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452302X16301619; https://doaj.org/toc/2452-302X

URL الوصول: https://doaj.org/article/1b06ca8dbecb4850b7f6c85e6a80bdc0

المؤلفون: Michael F Hill, Amish V Patel, Abigail Murphy, Holly M Smith, Cristi L Galindo, Laura Pentassuglia, Xuyang Peng, Carrie G Lenneman, Oghenerukevwe Odiete, David B Friedman, Marvin W Kronenberg, Siyuen Zheng, Zhongming Zhao, Yanna Song, Frank E Harrell, Maya Srinivas, Anindita Ganguly, Jennifer Iaci, Tom J Parry, Anthony O Caggiano, Douglas B Sawyer

المصدر: PLoS ONE, Vol 8, Iss 2, p e55741 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3578842?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/6ecd2547b5fc43149fdd21ebb39b5092

المؤلفون: Kimberly M. Freeman, Jennifer Iaci, Jonathan P. Jackson, Andrew Eisen, Ric Stanulis, Donald Button, Paul B. Watkins, Anthony O. Caggiano, Merrie Mosedale, Tom J. Parry, Kenneth R. Brouwer, Maya Srinivas

المصدر: Toxicological Sciences. 161:401-411

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Cell Survival, Bilirubin, medicine.drug_class, Neuregulin-1, Primary Cell Culture, Cmax, Biology, Toxicology, Toxicogenetics, Bile Acids and Salts, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Gene expression, medicine, Animals, Cytochrome P-450 CYP3A, Humans, Liver injury, Clinical Trials, Phase I as Topic, Bile acid, Acute-phase protein, Biological Transport, Hep G2 Cells, medicine.disease, Macaca fascicularis, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Liver, chemistry, 030220 oncology & carcinogenesis, Hepatocyte, Heart failure, Hepatocytes, Bile Ducts, Transcriptome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142f68e1e824a2207b7a4deef92d4f59
https://doi.org/10.1093/toxsci/kfx222

المؤلفون: J. Luis Guerrero, Anthony O. Caggiano, Douglas B. Sawyer, Erika L. Troy, Maya Srinivas, Ronald Zolty, Anindita Ganguly, Craig Hackett, Donald Button, Tom J. Parry, Andrea Vecchione, Jennifer Iaci

المصدر: European Journal of Pharmacology. 796:76-89

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Receptor, ErbB-4, Heart Ventricles, Neuregulin-1, Myocardial Infarction, CHO Cells, 030204 cardiovascular system & hematology, Anterior Descending Coronary Artery, Drug Administration Schedule, Mice, 03 medical and health sciences, Cricetulus, 0302 clinical medicine, ErbB, Cricetinae, Internal medicine, Ventricular Dysfunction, medicine, Animals, Humans, Amino Acid Sequence, Myocardial infarction, Neuregulin 1, Heart Failure, Pharmacology, Ejection fraction, biology, business.industry, medicine.disease, Rats, 3. Good health, 030104 developmental biology, Endocrinology, Cytoprotection, Doxorubicin, Heart failure, biology.protein, Cardiology, Neuregulin, Ligation, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe3e5bb0b1ba6f5279ddbcc8a85a157
https://doi.org/10.1016/j.ejphar.2016.12.024

المؤلفون: Jennifer Iaci, Anil Sindhurakar, Disha Gupta, Jason B. Carmel, Asht M. Mishra, Tom J. Parry

المصدر: Neurorehabilitation and Neural Repair. 31:387-396

مصطلحات موضوعية: 0301 basic medicine, Drug, media_common.quotation_subject, Drug Evaluation, Preclinical, Pyramidal Tracts, Article, Rats, Sprague-Dawley, Random Allocation, 03 medical and health sciences, 0302 clinical medicine, Forelimb, medicine, Animals, 4-Aminopyridine, Muscle, Skeletal, Spinal Cord Injuries, media_common, Pyramidal tracts, Electromyography, business.industry, Multiple sclerosis, Motor Cortex, Cervical Cord, General Medicine, Evoked Potentials, Motor, Spinal cord, medicine.disease, Electric Stimulation, Electrophysiology, 030104 developmental biology, medicine.anatomical_structure, Female, business, Microelectrodes, Neuroscience, 030217 neurology & neurosurgery, Central Nervous System Agents, Motor cortex, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca32ca51fd5246518e2391b205c08e7
https://doi.org/10.1177/1545968316688800

المؤلفون: Andrew Eisen, Lisa A. Mendes, Anthony O. Caggiano, Ping Z. Zhao, Carrie Geisberg Lenneman, Sarah A. Anderson, Douglas B. Sawyer, James A.S. Muldowney, Stephen Frohwein, Evan L. Brittain, Jennifer Iaci, Daniel J. Lenihan, Ronald Zolty

المصدر: JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 576-586 (2016)

مصطلحات موضوعية: 0301 basic medicine, Cardiac function curve, lcsh:Diseases of the circulatory (Cardiovascular) system, Nausea, NRG, neuregulin, CLINICAL RESEARCH, DLT, dose-limiting toxicity, 030204 cardiovascular system & hematology, HF, heart failure, neuregulin, 03 medical and health sciences, AUC, area under the curve, 0302 clinical medicine, Planned Dose, LVEF, left ventricular ejection fraction, medicine, Neuregulin 1, Ejection fraction, biology, LVSD, left ventricular systolic dysfunction, business.industry, systolic dysfunction, growth factor, medicine.disease, GGF, glial growth factor, 030104 developmental biology, Tolerability, lcsh:RC666-701, Anesthesia, Heart failure, Toxicity, biology.protein, cardiac repair, NYHA, New York Heart Association functional class, medicine.symptom, Cardiology and Cardiovascular Medicine, business, AE, adverse event, TEAE, treatment-emergent adverse event

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1b2e235d2739c2c3d4d48e933d19f8
http://europepmc.org/articles/PMC6113538

المؤلفون: Rod Moseanko, Leif A. Havton, Ernesto A. Salegio, Mark H. Tuszynski, James W. Fawcett, Adam R. Ferguson, Janet L. Weber, Jennifer Iaci, Stephanie Hawbecker, J. Russell Huie, Yvette S. Nout-Lomas, Barbara Haenzi, John H. Brock, Roger Pender, Jacqueline C. Bresnahan, Michael S. Beattie, Andrew R. Blight, Chase A. Weinholtz, Ephron S. Rosenzweig, Christina Cruzen, Justine J. Liang, Anthony O. Caggiano

المساهمون: Fawcett, James [0000-0002-7990-4568], Apollo - University of Cambridge Repository

المصدر: Nature neuroscience, vol 22, iss 8
Nature neuroscience

مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, Swine, Pyramidal Tracts, Neurodegenerative, Injections, Intralesional, 0302 clinical medicine, Psychology, Primate, Gray Matter, Spinal Cord Injury, Spinal cord injury, Motor Neurons, biology, General Neuroscience, Perineuronal net, 3. Good health, Intralesional, medicine.anatomical_structure, Treatment Outcome, Neurological, Cognitive Sciences, Microglia, medicine.symptom, medicine.medical_specialty, Physical Injury - Accidents and Adverse Effects, Inhibitory postsynaptic potential, Article, Injections, Lesion, 03 medical and health sciences, biology.animal, medicine, Extracellular, Animals, Traumatic Head and Spine Injury, Spinal Cord Injuries, Hand function, Neurology & Neurosurgery, business.industry, Neurosciences, Recovery of Function, Spinal cord, medicine.disease, Hand, Macaca mulatta, Axons, Chondroitinases and Chondroitin Lyases, 030104 developmental biology, Synapses, business, Neuroscience, 030217 neurology & neurosurgery, Psychomotor Performance

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8634f8d08ce496622c66fd92d80d94be
https://escholarship.org/uc/item/1n72g749

المؤلفون: Zhihong Huang, Jennifer Iaci, Tom J. Parry, Elias Pavlopoulos, JingMei Ren, Anthony O. Caggiano, Seth P. Finklestein

المصدر: Journal of Neuroscience Research. 94:253-265

مصطلحات موضوعية: 0301 basic medicine, biology, business.industry, Ischemia, medicine.disease, Effective dose (pharmacology), Neuroprotection, 03 medical and health sciences, Cellular and Molecular Neuroscience, 030104 developmental biology, 0302 clinical medicine, Anesthesia, Heart failure, biology.protein, Medicine, Neuregulin, Neuregulin 1, Dose Frequency, business, Stroke, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::362ad2f6bc299f81daab2a8f632350e9
https://doi.org/10.1002/jnr.23699

المؤلفون: A. Elizabeth Wagner, Anthony O. Caggiano, Jennifer Iaci, Richard Franklin

المصدر: Stroke. 49

مصطلحات موضوعية: Advanced and Specialized Nursing, Rodent, biology, business.industry, Pharmacology, Functional recovery, medicine.disease, biology.animal, Renin–angiotensin system, ACE inhibitor, medicine, Neurology (clinical), Cardiology and Cardiovascular Medicine, business, Stroke, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8530966c2379592cc78f19e829fd6664
https://doi.org/10.1161/str.49.suppl_1.tmp33

المؤلفون: Grant T. Generaux, Donald Button, Ric Stanulis, Anthony O. Caggiano, Brett A. Howell, Diane M. Longo, Merrie Mosedale, Daniel J. Antoine, Tom J. Parry, Paul B. Watkins, Andrew Eisen, Scott Q. Siler, Jennifer Iaci

المصدر: Longo, D M, Generaux, G T, Bengry-Howell, A, Siler, S Q, Antoine, D, Button, D, Caggiano, J A, Eisen, J A, Iaci, J, Stanulis, R, Parry, T, Mosedale, M & Watkins, P B 2017, ' Refining Liver Safety Risk Assessment : Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical Trials ', Clinical pharmacology and therapeutics, vol. 102, no. 6, pp. 961-969 . https://doi.org/10.1002/cpt.711
Clinical Pharmacology and Therapeutics

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Bilirubin, Neuregulin-1, Population, Apoptosis, Pharmacology, Gastroenterology, Risk Assessment, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Journal Article, Humans, Pharmacology (medical), education, Liver injury, education.field_of_study, Clinical Trials as Topic, Models, Statistical, biology, business.industry, Research, Alanine Transaminase, Articles, medicine.disease, Recombinant Proteins, Clinical trial, 030104 developmental biology, medicine.anatomical_structure, chemistry, Alanine transaminase, Liver, 030220 oncology & carcinogenesis, Hepatocyte, biology.protein, Biomarker (medicine), Risk assessment, business, Biomarkers

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd70ea640db5a0d3acd2dc98e1dfc91
https://www.pure.ed.ac.uk/ws/files/55790946/Antoine_D_Refining_Liver_Safety....pdf