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1دورية أكاديمية
المؤلفون: Jeremy R Edgerton, Dieter eJaeger
المصدر: Frontiers in Cellular Neuroscience, Vol 8 (2014)
مصطلحات موضوعية: Basal Ganglia, inhibition, optogenetics, bursting, Motor thalamus, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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المؤلفون: Christopher R Butter, Joshua Moon, John F. Harms, Stefanus J. Steyn, John T. Lazzaro, Rebecca E. O’Connor, Catherine A. Thorn, Clinton A Bourbonais, Eda Stark, Jeremy R. Edgerton, Michael Popiolek
المصدر: ACS Chemical Neuroscience. 10:1753-1764
مصطلحات موضوعية: Pyridines, Physiology, Cognitive Neuroscience, Prefrontal Cortex, Hippocampus, Striatum, Muscarinic Agonists, Hippocampal formation, CREB, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, Thiadiazoles, Muscarinic acetylcholine receptor, Animals, Prefrontal cortex, CA1 Region, Hippocampal, 030304 developmental biology, 0303 health sciences, biology, Chemistry, Receptor, Muscarinic M1, Cell Biology, General Medicine, Acetylcholine, Corpus Striatum, biology.protein, Xanomeline, Neuroscience, 030217 neurology & neurosurgery
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المؤلفون: Anthony R. Harris, Susan M. Lotarski, Michael Aaron Brodney, Michael Popiolek, Catherine A. Thorn, Stephen Jenkinson, Che Wah Lee, Jennifer E. Davoren, Stefanus J. Steyn, Lei Zhang, Terrence Peter Kenakin, Betty Pettersen, Sarah Grimwood, Damien Webb, Michelle R. Garnsey, Simeon Ramsey, John T. Lazzaro, Steven Victor O'neil, Lisa Nottebaum, Jean-Philippe Fortin, Jeremy R. Edgerton
المصدر: Journal of Medicinal Chemistry. 60:6649-6663
مصطلحات موضوعية: 0301 basic medicine, Agonist, Allosteric modulator, medicine.drug_class, Chemistry, Allosteric regulation, Muscarinic acetylcholine receptor M1, Pharmacology, 03 medical and health sciences, 030104 developmental biology, Drug Discovery, Convulsion, medicine, Molecular Medicine, Cholinergic, Structure–activity relationship, medicine.symptom, Receptor
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المؤلفون: Eda Stark, Catherine A. Thorn, Jeremy R. Edgerton, Michael Popiolek
المصدر: Hippocampus. 27:794-810
مصطلحات موضوعية: 0301 basic medicine, Cognitive Neuroscience, Glutamate receptor, Hippocampus, Hippocampal formation, Neurotransmission, 03 medical and health sciences, Glutamatergic, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, nervous system, chemistry, Schaffer collateral, medicine, Psychology, Xanomeline, Neuroscience, 030217 neurology & neurosurgery, Acetylcholine, medicine.drug
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المؤلفون: Susan M. Lotarski, Sarah Grimwood, Michael Popiolek, Veronica Reinhart, Jeremy R. Edgerton, Jennifer E. Davoren, Stefanus J. Steyn, John F. Harms, David P. Nguyen
المصدر: Biochemistry. 55:7073-7085
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M1, Pharmacology, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M5, Muscarinic acetylcholine receptor M4, Inositol, Inositol phosphate, 030217 neurology & neurosurgery
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المؤلفون: Deborah L. Smith, Sarah J. Neal, Lei Zhang, Jeremy R. Edgerton, Jennifer E. Davoren, Sarah Grimwood, John T. Lazzaro, Chewah Lee
المصدر: Molecular Pharmacology. 90:177-187
مصطلحات موضوعية: Male, 0301 basic medicine, Carbachol, Allosteric modulator, Pyridines, Stereochemistry, Allosteric regulation, CHO Cells, Isoindoles, Hippocampus, Rats, Sprague-Dawley, Radioligand Assay, 03 medical and health sciences, Cricetulus, 0302 clinical medicine, Allosteric Regulation, Cricetinae, Muscarinic acetylcholine receptor, medicine, Radioligand, Animals, Humans, Fluorometry, Pharmacology, Membranes, Chemistry, Ligand binding assay, Receptor, Muscarinic M1, N-Methylscopolamine, Acetylcholine, Electrophysiological Phenomena, Kinetics, HEK293 Cells, 030104 developmental biology, Positron-Emission Tomography, Autoradiography, Molecular Medicine, 030217 neurology & neurosurgery, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a4cbb153c3abcd01cb4427f9543370
https://doi.org/10.1124/mol.116.104737 -
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المؤلفون: Jennifer E, Davoren, Michelle, Garnsey, Betty, Pettersen, Michael A, Brodney, Jeremy R, Edgerton, Jean-Philippe, Fortin, Sarah, Grimwood, Anthony R, Harris, Stephen, Jenkinson, Terry, Kenakin, John T, Lazzaro, Che-Wah, Lee, Susan M, Lotarski, Lisa, Nottebaum, Steven V, O'Neil, Michael, Popiolek, Simeon, Ramsey, Stefanus J, Steyn, Catherine A, Thorn, Lei, Zhang, Damien, Webb
المصدر: Journal of medicinal chemistry. 60(15)
مصطلحات موضوعية: Diarrhea, Male, Lactams, Vomiting, Scopolamine, Isoindoles, Structure-Activity Relationship, Dogs, Allosteric Regulation, Piperidines, Seizures, Thiadiazoles, Animals, Humans, Donepezil, Rats, Wistar, Oxazoles, Sulfonamides, Receptor, Muscarinic M1, Mice, Inbred C57BL, Amphetamine, Drug Design, Indans, Microsomes, Liver, Ataxia, Female
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المؤلفون: Michael, Popiolek, David P, Nguyen, Veronica, Reinhart, Jeremy R, Edgerton, John, Harms, Susan M, Lotarski, Stefanus J, Steyn, Jennifer E, Davoren, Sarah, Grimwood
المصدر: Biochemistry. 55(51)
مصطلحات موضوعية: Male, Dose-Response Relationship, Drug, Inositol Phosphates, Dopamine Agents, Receptor, Muscarinic M1, Brain, CHO Cells, Motor Activity, Muscarinic Agonists, Hippocampus, Corpus Striatum, Electrophysiological Phenomena, Rats, Sprague-Dawley, Amphetamine, Mice, Cricetulus, Cricetinae, Animals, Humans, Calcium
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المؤلفون: Evan P. Lebois, S. Xi, Michael Popiolek, Catherine A. Thorn, Jeremy R. Edgerton
المصدر: Neuropharmacology. 136
مصطلحات موضوعية: 0301 basic medicine, Central Nervous System, Aging, Central nervous system, Biology, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Alzheimer Disease, Muscarinic acetylcholine receptor, medicine, Animals, Humans, Receptor, Neuropharmacology, G protein-coupled receptor, Pharmacology, Receptors, Muscarinic, 030104 developmental biology, Metabotropic receptor, medicine.anatomical_structure, Cholinergic, Neuroscience, 030217 neurology & neurosurgery, Acetylcholine, medicine.drug
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المؤلفون: Catherine A, Thorn, Michael, Popiolek, Eda, Stark, Jeremy R, Edgerton
المصدر: Hippocampus
مصطلحات موضوعية: Male, Receptor, Muscarinic M4, muscarinic, Receptor, Muscarinic M1, electrophysiology, Synaptic Transmission, acetylcholine, Rats, Rats, Sprague-Dawley, Schaffer collateral, temporoammonic, nervous system, Animals, CA1 Region, Hippocampal, Research Articles, Research Article