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1
المؤلفون: Haifeng Tang, Zack Zhiqiang Guo, Lee-Yuh Pai, Adam B. Weinglass, Xin Gu, Shuzhi Dong, Alexander Pasternak, Yang Yu, Kathleen A. Sullivan, Mengwei Hu, Kelsey VanGelder, Gloria J. Zingaro, Sophie Roy, Jessica Liu, Qinghong Fu, Birgit T. Priest, Michael Margulis, Brande Thomas-Fowlkes, Pierre Morissette, Robin E. Haimbach, Zhicai Wu, Juliann Ehrhart, Karen Owens, Caryn Hampton, Zhi-Cai Shi, Jessica Frie, Ron Ferguson, Shiyao Xu, Vincent Tong
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:2559-2566
مصطلحات موضوعية: 0301 basic medicine, ERG1 Potassium Channel, Scaffold, Clinical Biochemistry, hERG, Pharmaceutical Science, Pharmacology, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, Dogs, 0302 clinical medicine, Thiadiazoles, In vivo, Rats, Inbred SHR, Drug Discovery, Potassium Channel Blockers, medicine, Animals, Structure–activity relationship, Spiro Compounds, Potassium Channels, Inwardly Rectifying, Molecular Biology, biology, Chemistry, Organic Chemistry, Potassium channel blocker, Rats, Disease Models, Animal, Pyrimidines, 030104 developmental biology, 030220 oncology & carcinogenesis, Hypertension, ROMK, biology.protein, Molecular Medicine, Pharmacophore, Half-Life, medicine.drug
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2
المؤلفون: Lee-Yuh Pai, Aaron Corona, Harry R. Chobanian, John P. Felix, Matthew J. Clements, Karen Owens, Haifeng Tang, Brande Thomas-Fowlkes, Kathleen A. Sullivan, Alexander Pasternak, Caryn Hampton, Jessica Frie, Vincent Tong, Ron Ferguson, Jessica Liu, Birgit T. Priest, Barbara Pio, Yan Guo, Elizabeth Joshi, Nardos Teumelsan, Ling Xu, Martin Köhler, Joseph M. Metzger, Zach Guo, Kevin M. Maloney
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:1109-1114
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, hERG, Pharmaceutical Science, Diuresis, Biochemistry, Natriuresis, Sulfone, 03 medical and health sciences, chemistry.chemical_compound, Heterocyclic Compounds, Rats, Inbred SHR, Drug Discovery, medicine, Animals, Moiety, Organic chemistry, Sulfones, Enzyme Inhibitors, Potassium Channels, Inwardly Rectifying, Diuretics, Molecular Biology, biology, Chemistry, Organic Chemistry, Rats, 030104 developmental biology, Drug Design, ROMK, biology.protein, Molecular Medicine, Diuretic, Selectivity
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3
المؤلفون: Lee-Yuh Pai, Yuping Zhu, Richard Visconti, Xiaoyan Zhou, John P. Felix, Melba Hernandez, Jing Chen, Michael Margulis, Nardos Teumelsan, Sophie Roy, Kathleen A. Sullivan, Jessica Liu, Joseph M. Metzger, Aaron Corona, Gregory J. Kaczorowski, Maria L. Garcia, Lihu Yang, Shawn P. Walsh, Birgit T. Priest, Alexander Pasternak, Caryn Hampton, Emma R. Parmee, Vincent Tong, Brande Thomas-Fowlkes, Haifeng Tang, Magdalena Alonso-Galicia, Kashmira Shah, Michael J. Forrest, Richard M. Brochu, Ross Bentley, Sookhee Ha, Karen Owens, Aurash Shahripour, Andrew M. Swensen, Jessica Frie, Adam B. Weinglass, Timothy Bailey
المصدر: ACS Medicinal Chemistry Letters. 6:747-752
مصطلحات موضوعية: Pharmacokinetics, Chemistry, Pharmacodynamics, Organic Chemistry, Drug Discovery, ROMK, Pharmacology, Biochemistry
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4
المؤلفون: Shawn P. Walsh, Jessica Frie, Nardos Teumelsan, Maria L. Garcia, Karen Owens, Sophie Roy, Caryn Hampton, Reynalda K. de Jesus, Birgit T. Priest, Magdalena Alonso-Galicia, Aurash Shahripour, Richard M. Brochu, Juliann Ehrhart, Andrew M. Swensen, Haifeng Tang, Timothy Bailey, Alexander Pasternak, Lee-Yuh Pai, Yuping Zhu, Lihu Yang, Gregory J. Kaczorowski, John P. Felix, Melba Hernandez, Brande Thomas-Fowlkes, Xiaoyan Zhou
المصدر: Bioorganicmedicinal chemistry letters. 26(9)
مصطلحات موضوعية: 0301 basic medicine, ERG1 Potassium Channel, medicine.medical_treatment, Clinical Biochemistry, hERG, Pharmaceutical Science, Pharmacology, Biochemistry, Piperazines, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, In vivo, Heterocyclic Compounds, Drug Discovery, medicine, Potency, Structure–activity relationship, Molecular Biology, biology, Chemistry, Organic Chemistry, Small molecule, Piperazine, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, ROMK, Molecular Medicine, Diuretic
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5
المؤلفون: M. Gerard Waters, Steven L. Colletti, Andrew K.P. Taggart, Qiaolin Deng, Daria M. Marley, Xinchun Tong, Jessica Frie, Richard Beresis, Tian-Quan Cai, Ning Ren, Junying Wang, James R. Tata, Kang Cheng, Ester Carballo-Jane
المصدر: Bioorganicmedicinal chemistry letters. 18(18)
مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Receptors, Nicotinic, Biochemistry, Niacin, Receptors, G-Protein-Coupled, Structure-Activity Relationship, Drug Discovery, Combinatorial Chemistry Techniques, Humans, ortho-Aminobenzoates, Homology modeling, Nicotinic Agonists, Binding site, Molecular Biology, G protein-coupled receptor, Binding Sites, biology, Molecular Structure, Chemistry, Organic Chemistry, Ligand (biochemistry), Nicotinic agonist, Docking (molecular), Rhodopsin, biology.protein, Molecular Medicine
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6
المؤلفون: Catherine E. Fitzgerald, Ruixiu Wang, Elizabeth C. Dixon, Dennis M. Schmatz, Stephen J. O'Keefe, James B. Doherty, Jessica Frie, Cheryl D. Schwartz, Dennis M. Zaller, Chris M. Thompson, Gene Porter, Giovanna Scapin, James E. Thompson, Wesley L. Shoop, Suresh B. Singh, Andrea Woods, Elizabeth A. Nichols, Koppara Samuel, Edward A. O'Neill, Bernard K. Choi, Steven L. Colletti, Sanjeev Kumar
المصدر: Journal of medicinal chemistry. 46(3)
مصطلحات موضوعية: Models, Molecular, Imidazopyridine, biology, Bicyclic molecule, Hydrogen bond, Stereochemistry, Chemistry, p38 mitogen-activated protein kinases, Chemical synthesis, p38 Mitogen-Activated Protein Kinases, Pyridazines, Mice, Structure-Activity Relationship, Enzyme inhibitor, Mitogen-activated protein kinase, Drug Discovery, biology.protein, Molecular Medicine, Animals, Enzyme Inhibitors, Mitogen-Activated Protein Kinases, Protein kinase A
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7دورية أكاديمية
المؤلفون: Alison Smith, Lynn Hakki, Jessica Friedman, Rebecca Schroll, Chrissy Guidry, Patrick McGrew, Danielle Tatum, Juan Duchesne
المصدر: Journal of Endovascular Resuscitation and Trauma Management, Vol 3, Iss 3 (2019)
مصطلحات موضوعية: Damage Control, Resuscitation, Time, Diseases of the circulatory (Cardiovascular) system, RC666-701, Surgery, RD1-811
وصف الملف: electronic resource
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8دورية أكاديمية
المؤلفون: Subhojit Chakraborty, Joseph Indeck, Philipp Steinmetz, Jessica Friess, Kavan Hazeli, Amber L. Genau
المصدر: Metals, Vol 10, Iss 12, p 1638 (2020)
مصطلحات موضوعية: cast iron, digital image correlation (DIC), mechanical properties, graphite morphology, ductile failure, brittle failure, Mining engineering. Metallurgy, TN1-997
وصف الملف: electronic resource
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9دورية أكاديمية
المؤلفون: Xintao Zhu, Fu Wang, Shuaipeng Zhang, Tobias Wittenzellner, Jessica Frieß, Dexin Ma, Andreas Bührig-Polaczek
المصدر: Materials, Vol 12, Iss 11, p 1781 (2019)
مصطلحات موضوعية: grain selector, reduction the dimensionality, 2D grain selector, Ni-based single crystal superalloys, Technology, Electrical engineering. Electronics. Nuclear engineering, TK1-9971, Engineering (General). Civil engineering (General), TA1-2040, Microscopy, QH201-278.5, Descriptive and experimental mechanics, QC120-168.85
وصف الملف: electronic resource
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10دورية أكاديمية
المؤلفون: Conrad Kunick, Maximilian Wabnik, Renate Schnerre, Michael Haese, Bader Masri, Janine Joostberends, Jessica Friedrichs, Frederik Berndt, Sebastian Wölfel
المصدر: Molbank, Vol 2012, Iss 4, p M785 (2012)
مصطلحات موضوعية: tetrachlorophthalimide, tetrachlorophthalic anhydride, 2-aminoimidazole, Inorganic chemistry, QD146-197
وصف الملف: electronic resource