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1دورية أكاديمية
المؤلفون: Jessica Whritenour, Mira Ko, Qing Zong, Jianying Wang, Karrie Tartaro, Patricia Schneider, Ellen Olson, Maria Van Volkenburg, Jose Serrano, Paul Hayashi, Robert Fontana, Naga Chalasani, Herbert L. Bonkovsky
المصدر: Journal of Immunotoxicology, Vol 14, Iss 1, Pp 31-38 (2017)
مصطلحات موضوعية: Allergic reactions, immuno-allergic, drug-induced liver injury, drugs, hepatitis, lymphocytes, lymphocyte transformation test, Immunologic diseases. Allergy, RC581-607, Toxicology. Poisons, RA1190-1270
وصف الملف: electronic resource
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المؤلفون: Krista L. Dobo, Michelle O. Kenyon, Olivier Dirat, Maria Engel, Andrew Fleetwood, Matthew Martin, Susan Mattano, Alyssa Musso, James Christopher McWilliams, Alexandros Papanikolaou, Patricia Parris, Jessica Whritenour, Shu Yu, Amit S. Kalgutkar
المصدر: Chemical Research in Toxicology. 35:475-489
مصطلحات موضوعية: General Medicine, Toxicology
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المؤلفون: Patricia Parris, Geraldine Whelan, Anders Burild, Jessica Whritenour, Uma Bruen, Joel Bercu, Courtney Callis, Jessica Graham, Esther Johann, Troy Griffin, Martin Kohan, Elizabeth A. Martin, Melisa Masuda-Herrera, Brad Stanard, Eric Tien, Maureen Cruz, Lee Nagao
المصدر: Critical Reviews in Toxicology. 52:125-138
مصطلحات موضوعية: Pharmaceutical Preparations, Humans, Drug Contamination, Toxicology, Risk Assessment, Drug Packaging
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المؤلفون: Jessica Whritenour, Rhiannon N. Hardwick, Catherine J. Betts, Maike Thamsen, Radhakrishna Sura, Kristin M. Fabre, Elad H. Kaufman
المصدر: Lab on a Chip. 20:199-214
مصطلحات موضوعية: Drug, Cell type, Drug Industry, media_common.quotation_subject, Biomedical Engineering, Bioengineering, Computational biology, Models, Biological, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Drug Development, Lab-On-A-Chip Devices, Animals, Humans, Medicine, Model development, Skin, 030304 developmental biology, media_common, Pharmaceutical industry, 0303 health sciences, business.industry, General Chemistry, Skin toxicity, Pharmaceutical Preparations, Drug development, Preclinical testing, 030220 oncology & carcinogenesis, business, Phototoxicity
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80dfc071343eaf8f78bad1d63f87da94
https://doi.org/10.1039/c9lc00519f -
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المؤلفون: John B. Watson, L. Bibby, S. Ahmed, Jessica Whritenour, Xiao-Nong Wang, L. Darby, Anne M. Dickinson, M.M. Ahmed
المصدر: Toxicology and Applied Pharmacology. 369:39-48
مصطلحات موضوعية: 0301 basic medicine, Phenytoin, Drug, T-Lymphocytes, media_common.quotation_subject, T cell, Pharmacology, Lymphocyte Activation, Toxicology, Risk Assessment, Drug Hypersensitivity, Tissue Culture Techniques, Interferon-gamma, 03 medical and health sciences, 0302 clinical medicine, Abacavir, In vivo, medicine, Humans, Interferon gamma, Cell Proliferation, Skin, media_common, business.industry, Reproducibility of Results, Carbamazepine, Skin Irritancy Tests, Coculture Techniques, Molecular Weight, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Irritants, Lumiracoxib, business, medicine.drug
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المؤلفون: Lisa D. Marroquin, Eri Uchida, Yuka Uchida, Shingo Oda, Jessica Whritenour, Yusuke Matsui, Petra H. Koza-Taylor, Masanori Hizue, Michael D. Aleo, Tsuyoshi Yokoi
المصدر: Archives of toxicology. 95(1)
مصطلحات موضوعية: 0301 basic medicine, Genetic Markers, Carcinoma, Hepatocellular, Cell Survival, Health, Toxicology and Mutagenesis, 010501 environmental sciences, Toxicology, 01 natural sciences, Peripheral blood mononuclear cell, Proto-Oncogene Mas, Risk Assessment, Receptor tyrosine kinase, 03 medical and health sciences, Immune system, medicine, Humans, 0105 earth and related environmental sciences, Oligonucleotide Array Sequence Analysis, Liver injury, biology, business.industry, Gene Expression Profiling, Liver Neoplasms, General Medicine, Hep G2 Cells, medicine.disease, In vitro, Coculture Techniques, 030104 developmental biology, Cell culture, Hepatocellular carcinoma, biology.protein, Cancer research, Hepatocytes, Leukocytes, Mononuclear, Biomarker (medicine), Chemical and Drug Induced Liver Injury, business, Transcriptome
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المؤلفون: Ernst Ahlberg, Tatyana Y. Doktorova, Alexis Parenty, Thomas Exner, David Woolley, Angela White, Alessandro Brigo, Scott Miller, Jason Magby, Rahul Parakhia, David W. Roberts, Thibaud Weiler, Raymond R. Tice, David Faulkner, Eckart Krupp, Candice Y. Johnson, Amanda Giddings, Ana Theresa Paulino, Jessica Whritenour, Véronique Gervais, Barry Hardy, Ian M. Fearon, Louise Neilson, Alexandre Paulino, Sarah Campbell, Shayne C. Gad, Sol Bobst, Reinhard Stidl, Liat Lomnitski, Anna Vuorinen, Lawrence Milchak, Craig Zwickl, Harald Schlecker, Wolfgang Muster, David T. Szabo, Lisa Beilke, Mark T. D. Cronin, Daniel Urbisch, Glenn J. Myatt, Joel P. Bercu, Robert A. Jolly, Brian A. Wall, Markus Fehr, Romualdo Benigni, Lennart T. Anger, Ian Crooks, Patricia Parris, Kevin P. Cross, Joerg Wichard, David Bower, Diana Suarez-Rodrigez, Jedd Hillegass, Catrin Hasselgren, Susanne Glowienke, Jordi Mestres
المصدر: Regul Toxicol Pharmacol
مصطلحات موضوعية: Keratinocytes, RM, Computer science, In silico, RL, Expert alerts, Computational toxicology, Pharmacology and Toxicology, 010501 environmental sciences, Toxicology, Animal Testing Alternatives, Dermatitis, Contact, 030226 pharmacology & pharmacy, 01 natural sciences, Risk Assessment, Article, (Q)SAR, 03 medical and health sciences, 0302 clinical medicine, Adverse Outcome Pathway, Animals, Humans, Computer Simulation, Lymphocytes, Reliability (statistics), 0105 earth and related environmental sciences, Protocol (science), Weight of evidence, Integrated approaches to testing and assessment (IATA), Skin sensitization, Extractables and leachables, In silico toxicology, General Medicine, Dendritic Cells, Allergens, Farmakologi och toxikologi, Expert review, Risk analysis (engineering), Computational toxicology protocols, Defined approach, Haptens
وصف الملف: application/pdf
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المؤلفون: R. Scott Obach, Ellen Evans, Nasir K. Khan, Jessica Whritenour, Changhua Ji, Susanna Tse, Xu Zhu, Michelle Hemkens, Gregory S. Walker, Martin Finkelstein, Mausumee Guha, Ernesto Callegari
المصدر: Chemical research in toxicology. 33(1)
مصطلحات موضوعية: Antineoplastic Agents, 010501 environmental sciences, Pharmacology, Toxicology, 01 natural sciences, Drug Hypersensitivity, 03 medical and health sciences, chemistry.chemical_compound, Prostate cancer, Nitriles, Phenylthiohydantoin, medicine, Androgen Receptor Antagonists, Enzalutamide, Animals, Humans, Lymphocytes, Bovine serum albumin, 030304 developmental biology, 0105 earth and related environmental sciences, 0303 health sciences, biology, Apalutamide, General Medicine, Glutathione, medicine.disease, Rash, Androgen receptor, Mice, Inbred C57BL, Disease Models, Animal, chemistry, Thiohydantoins, Benzamides, biology.protein, Hepatocytes, Female, medicine.symptom, Cysteine, Protein Binding
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المؤلفون: Daniel P. Walker, Antonia F. Stepan, Mark A. Moen, Gregg D. Cappon, Christopher Houle, Annie C Won, Joshua R. Dunetz, Michael John Bohanon, Lei Zhang, Marc B. Skaddan, Patrick Robert Verhoest, Susan E. Drozda, Xinjun Hou, Kenneth R. Zasadny, Julie Cianfrogna, Deborah L. Smith, Ann S. Wright, John T. Lazzaro, Steven Victor O'neil, Patrick Trapa, Emily Miller, Somraj Ghosh, Gabriela Barreiro, John M. Marcek, Margaret M. Zaleska, Jason Barricklow, Michelle Marie Claffey, Lois K. Chenard, Jessica Mancuso, Christopher L. Shaffer, Jessica Whritenour, Gayatri Balan, Brian P. Boscoe, Vinod D. Parikh, Karen J. Coffman, Laigao Chen, Isao Sakurada, Jamison B. Tuttle, Matthew R. Reese, Karki Kapil Kumar
المصدر: Journal of Medicinal Chemistry. 60:7764-7780
مصطلحات موضوعية: Male, 0301 basic medicine, Allosteric modulator, Pyridines, Receptor, Metabotropic Glutamate 5, Alkyne, Pharmacology, 030226 pharmacology & pharmacy, Rats, Sprague-Dawley, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Immune system, Allosteric Regulation, Drug Discovery, Animals, Humans, Structure–activity relationship, Receptor, chemistry.chemical_classification, Chemistry, Metabotropic glutamate receptor 5, HEK 293 cells, Rats, Molecular Docking Simulation, HEK293 Cells, 030104 developmental biology, Toxicity, Molecular Medicine, Female, Heterocyclic Compounds, 3-Ring
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المؤلفون: Patricia A. Schneider, Robert J. Fontana, Ellen Olson, Maria A. Van Volkenburg, Jessica Whritenour, Jose Serrano, Jianying Wang, Paul H. Hayashi, Karrie Tartaro, Mira Ko, Naga Chalasani, Herbert L. Bonkovsky, Qing Zong
المصدر: Journal of Immunotoxicology, Vol 14, Iss 1, Pp 31-38 (2017)
مصطلحات موضوعية: lymphocytes, 0301 basic medicine, Granzyme B production, Lymphocyte, Adaptive Immunity, Lymphocyte Activation, Toxicology, Granzymes, drugs, 0302 clinical medicine, hepatitis, Cells, Cultured, Sensitization, media_common, Liver injury, Acquired immune system, medicine.anatomical_structure, Acute Disease, Cytokines, 030211 gastroenterology & hepatology, Chemical and Drug Induced Liver Injury, drug-induced liver injury, lcsh:Immunologic diseases. Allergy, Drug, media_common.quotation_subject, Immunology, Immunologic Tests, Article, Diagnosis, Differential, Drug Hypersensitivity, 03 medical and health sciences, Immune system, lcsh:RA1190-1270, Isoniazid, medicine, Humans, lymphocyte transformation test, Cell Proliferation, lcsh:Toxicology. Poisons, Hepatitis, business.industry, medicine.disease, 030104 developmental biology, immuno-allergic, Leukocytes, Mononuclear, Allergic reactions, Feasibility Studies, lcsh:RC581-607, business, Follow-Up Studies
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