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1دورية أكاديمية
المصدر: Antibiotics, Vol 5, Iss 3, p 26 (2016)
مصطلحات موضوعية: antibiotic, biotin, biotin protein ligase, Staphylococcus aureus, inhibitor design, X-ray crystallography, in situ click chemistry, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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2
المؤلفون: Kwangjun Lee, Andrew D. Abell, Steven W. Polyak, Beatriz Blanco-Rodriguez, John B. Bruning, Danielle Cini, Grant W. Booker, Robert W. Milne, Benjamin Noll, Andrew J. Hayes, Andrew C Marshall, Ashleigh S. Paparella, Jiage Feng, Matthew C.J. Wilce, Jingxian Yu, William Tieu
المساهمون: Lee, Kwang Jun, Tieu, William, Blanco-Rodriguez, Beatriz, Paparella, Ashleigh S, Yu, Jingxian, Hayes, Andrew, Feng, Jiage, Marshall, Andrew C, Noll, Benjamin, Milne, Robert, Cini, Danielle, Wilce, Matthew CJ, Booker, Grant W, Bruning, John B, Polyak, Steven W, Abell, Andrew D
المصدر: ACS Chemical Biology. 14:1990-1997
مصطلحات موضوعية: pharmacokinetic profile, 0301 basic medicine, Staphylococcus aureus, medicine.drug_class, Antibiotics, Microbial Sensitivity Tests, Molecular Dynamics Simulation, Crystallography, X-Ray, medicine.disease_cause, 01 natural sciences, Biochemistry, metabolic stability, Microbiology, Mice, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Drug Stability, Biotin, medicine, Animals, Carbon-Nitrogen Ligases, Enzyme Inhibitors, chemistry.chemical_classification, Sulfonamides, DNA ligase, 010405 organic chemistry, molecular dynamics simulations, General Medicine, Phosphate, Anti-Bacterial Agents, Rats, 0104 chemical sciences, Sulfonamide, 030104 developmental biology, chemistry, Drug Design, Molecular Medicine
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3
المؤلفون: Wanida Phetsang, Mark A. T. Blaskovich, Zikai Feng, Ashleigh S. Paparella, Jiage Feng, Mark E. Cooper, Andrew D. Abell, Beatriz Blanco-Rodriguez, Grant W. Booker, Steven W. Polyak
المساهمون: Paparella, Ashleigh S, Feng, Jiage, Blanco-Rodriguez, Beatriz, Feng, Zikai, Phetsang, Wanida, Blaskovich, Mark AT, Cooper, Matthew A, Booker, Grant W, Polyak, Steven W, Abell, Andrew D
المصدر: Tetrahedron. 74:1175-1183
مصطلحات موضوعية: staphylococcus aureus, 0301 basic medicine, enzyme inhibitors, Mutant, medicine.disease_cause, 01 natural sciences, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Biotin, antibiotic, Drug Discovery, medicine, Fluorescence microscope, biotin protein ligase, Escherichia coli, chemistry.chemical_classification, DNA ligase, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, biology.organism_classification, Molecular biology, 0104 chemical sciences, 030104 developmental biology, Staphylococcus aureus, azide-alkyne cycloaddition, Efflux, Bacteria
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المؤلفون: Sarah Clark, Andrew J. Hayes, Ashleigh S. Paparella, Grant W. Booker, David Heim, Steven W. Polyak, William Tieu, Andrew D. Abell, Jiage Feng
المساهمون: Feng, Jiage, Paparella, Ashleigh S, Tieu, William, Heim, David, Clark, Sarah, Hayes, Andrew, Booker, Grant W, Polyak, Steven W, Abell, Andrew D
المصدر: ACS Medicinal Chemistry Letters. 7:1068-1072
مصطلحات موضوعية: inorganic chemicals, 0301 basic medicine, Staphylococcus aureus, enzyme inhibitors, Binding pocket, Biology, medicine.disease_cause, Biochemistry, antibiotics, 03 medical and health sciences, chemistry.chemical_compound, Biotin, Drug Discovery, Ribose, medicine, biotin protein ligase, Cytotoxicity, chemistry.chemical_classification, DNA ligase, Organic Chemistry, 030104 developmental biology, chemistry, Hepg2 cells, Benzyl group
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5
المؤلفون: Steven W. Polyak, Sonali Deshmukh, Grant W. Booker, Andrew D. Abell, Zikai Feng, Andrew J. Hayes, Matthew C.J. Wilce, Ashleigh S. Paparella, Danielle Cini, Kwang J. Lee, Jiage Feng
المساهمون: Paparella, Ashleigh S, Lee, Kwang Jun, Hayes, Andrew J, Feng, Jiage, Feng, Zikai, Cini, Danielle, Deshmukh, Sonali, Booker, Grant W, Wilce, Matthew CJ, Polyak, Steven W, Abell, Andrew D
المصدر: ACS infectious diseases. 4(2)
مصطلحات موضوعية: 0301 basic medicine, inorganic chemicals, Models, Molecular, Staphylococcus aureus, Halogenation, enzyme inhibitor, Molecular Conformation, Biotin, Microbial Sensitivity Tests, Biology, medicine.disease_cause, Ligases, 03 medical and health sciences, chemistry.chemical_compound, Minimum inhibitory concentration, antibiotic, medicine, Humans, biotin protein ligase, Binding site, Enzyme Inhibitors, chemistry.chemical_classification, DNA ligase, Binding Sites, Dose-Response Relationship, Drug, Molecular Structure, Molecular biology, Anti-Bacterial Agents, 030104 developmental biology, Infectious Diseases, Biochemistry, chemistry, Enzyme inhibitor, biology.protein, Antibacterial activity, Protein Binding
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المؤلفون: Jiage, Feng, Ashleigh S, Paparella, William, Tieu, David, Heim, Sarah, Clark, Andrew, Hayes, Grant W, Booker, Steven W, Polyak, Andrew D, Abell
المصدر: ACS medicinal chemistry letters. 7(12)
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7
المساهمون: Feng, Jiage, Paparella, Ashleigh S, Booker, Grant W, Polyak, Steven W, Abell, Andrew D
المصدر: Antibiotics
Antibiotics, Vol 5, Iss 3, p 26 (2016)مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Staphylococcus aureus, Mutant, Review, Biology, medicine.disease_cause, 01 natural sciences, Biochemistry, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Biotin, biotin, antibiotic, medicine, Pharmacology (medical), biotin protein ligase, General Pharmacology, Toxicology and Pharmaceutics, inhibitor design, X-ray crystallography, chemistry.chemical_classification, DNA ligase, 010405 organic chemistry, lcsh:RM1-950, Pathogenic bacteria, biology.organism_classification, 3. Good health, 0104 chemical sciences, in situ click chemistry, 030104 developmental biology, Infectious Diseases, Enzyme, lcsh:Therapeutics. Pharmacology, chemistry, Linker, Bacteria
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