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المؤلفون: Kanak Raina, Chris D. Forbes, Rebecca Stronk, Jonathan P. Rappi, Kyle J. Eastman, Samuel W. Gerritz, Xinheng Yu, Hao Li, Amit Bhardwaj, Mia Forgione, Abigail Hundt, Madeline P. King, Zoe M. Posner, Allison Denny, Andrew McGovern, David E. Puleo, Ethan Garvin, Rebekka Chenard, Nilesh Zaware, James J. Mousseau, Jennifer Macaluso, Michael Martin, Kyle Bassoli, Kelli Jones, Marco Garcia, Katia Howard, Levi M. Smith, Jinshan M. Chen, Cesar A. De Leon, John Hines, Katherine J. Kayser-Bricker, Craig M. Crews
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::23ae61c78302824016b90ccec8643f82
https://doi.org/10.1101/2023.01.01.522436 -
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المؤلفون: Jennifer A. Young, Mark Edward Flanagan, Jinshan M. Chen, Carmen N. Garcia-Irizarry, R. Scott Obach, Brandon P. Schuff, Jeremy T. Starr, Upendra P. Dahal, Daniel P. Uccello, Adam M. Gilbert
المصدر: MedChemComm. 7:864-872
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Chemistry, Organic Chemistry, Pharmaceutical Science, Protonation, Biochemistry, Medicinal chemistry, 03 medical and health sciences, 030104 developmental biology, Nucleophile, Covalent bond, Drug Discovery, Electrophile, Molecular Medicine, Moiety, Organic chemistry, Reactivity (chemistry), Amine gas treating, Cysteine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ef76804ac11f6e5b90506d0944cbc187
https://doi.org/10.1039/c6md00017g -
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المؤلفون: Daniel P. Uccello, Jeremy T. Starr, Matthew Merrill Hayward, R. Scott Obach, Mark C. Noe, Adam M. Gilbert, Justin I. Montgomery, Mark Edward Flanagan, Veerabahu Shanmugasundaram, Dennis P. Anderson, Ann Aulabaugh, Ye Che, Matthew Frank Brown, Michael J. Shapiro, Chao Li, Tim F. Ryder, Stacey R. Oppenheimer, Laurence Philippe, Gregory S. Walker, Yan Wu, Brandon P. Schuff, Joseph A. Abramite, Jinshan M. Chen, Justin G. Stroh, Upendra P. Dahal
المصدر: Journal of Medicinal Chemistry. 57:10072-10079
مصطلحات موضوعية: chemistry.chemical_classification, Chemistry, Stereochemistry, Kinetics, food and beverages, Glutathione, Mass Spectrometry, chemistry.chemical_compound, Enzyme, Pharmaceutical Preparations, Nucleophile, Covalent bond, Drug Design, Drug Discovery, Electrophile, Humans, Molecular Medicine, Reactivity (chemistry), Enzyme Inhibitors, Selectivity, Nuclear Magnetic Resonance, Biomolecular
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المؤلفون: Jean S. Beebe, William M. Hungerford, Nandini Chaturbhai Patel, Heather N. Frost, Susan Deborah Lagreca, Cathy Soderstrom, Shefali Kakar, Doug Savage, Matthew David Wessel, Matthew A. Marx, Merin Boehm, Thompson Carl Brian, Jinshan M. Chen, Connell Richard D, Nandell F. Keene, Elizabeth Knauth, Gary Borzillo, Aaron Kanter, Yong Lu, Joel Morris, Martin A. Berliner, Patrick Vincent, Bruce D. Cohen, George T. Tkalcevic, Joel T. Arcari, Deborah A. Gordon, James J. Valentine, Tracey Clark, Louis Martinez-Alsina, Vincent Bernardo, Felix Vajdos, Norma Jacqueline Tom
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:3059-3063
مصطلحات موضوعية: Male, Benzimidazole, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Biochemistry, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Neoplasms, Drug Discovery, Animals, Humans, Structure–activity relationship, Pyrroles, Protein Kinase Inhibitors, Molecular Biology, Cell Proliferation, 4-aminopyrrolopyrimidine, Dose-Response Relationship, Drug, Molecular Structure, Drug discovery, Kinase, Organic Chemistry, Receptor, TIE-2, Xenograft Model Antitumor Assays, In vitro, Rats, Pyrimidines, chemistry, Cell culture, Molecular Medicine, Growth inhibition
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المؤلفون: Lisa Mullins, Daniel P. Uccello, Justin I. Montgomery, Ye Che, John P. O'Donnell, Mark S. Plummer, Joseph A. Abramite, Seung Won Chung, Loren M. Price, Mark C. Noe, Laura A. McAllister, Rose Barham, Mark J. Mitton-Fry, Andrew P. Tomaras, Usa Reilly, Matthew Frank Brown, Jinshan M. Chen, Joseph Penzien, Carol A. Menard, Veerabahu Shanmugasundaram, Robert M. Oliver
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:6832-6838
مصطلحات موضوعية: Gram-negative bacteria, Klebsiella pneumoniae, Clinical Biochemistry, Pharmaceutical Science, Microbial Sensitivity Tests, Hydroxamic Acids, Biochemistry, Amidohydrolases, Structure-Activity Relationship, chemistry.chemical_compound, Heterocyclic Compounds, Gram-Negative Bacteria, Drug Discovery, Structure–activity relationship, Sulfones, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Hydroxamic acid, biology, Organic Chemistry, biology.organism_classification, Anti-Bacterial Agents, Enzyme, chemistry, Pseudomonas aeruginosa, Molecular Medicine, Antibacterial activity, Bacterial outer membrane, Bacteria
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المؤلفون: Li Xing, Jane M. Withka, Guoyun Bai, Mark E. Bunnage, Bruce Allen Lefker, Leslie Anthony Dakin, Sheng Tan, Shenping Liu, Mary Ellen Banker, Parag Sahasrabudhe, Ariamala Gopalsamy, Atli Thorarensen, Hua Xu, Jennifer A. Young, Joerg Bussenius, Boris A. Chrunyk, Jinshan M. Chen, Kieran F. Geoghegan, Stephen W. Wright, Suman Shanker, Jeremy T. Starr, Paul Balbo, Xiayang Qiu, Zuojun Guo, Wei Li, Lyn H. Jones, Fabien Vincent, Lise R. Hoth
المصدر: Scientific Reports
مصطلحات موضوعية: Keratinocytes, 0301 basic medicine, Macrocyclic Compounds, Plasma protein binding, Molecular Dynamics Simulation, Pharmacology, Peptides, Cyclic, Article, Small Molecule Libraries, Structure-Activity Relationship, 03 medical and health sciences, Immune system, Humans, Structure–activity relationship, Binding site, Receptor, Cells, Cultured, Peptide ligand, Binding Sites, Multidisciplinary, biology, Interleukin-17, 030104 developmental biology, Drug Design, biology.protein, Interleukin 17, Antibody, Algorithms, Protein Binding
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