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1
المؤلفون: Jian Luo, Jinqian Liu, Jane Zhang, Jonathan B. Houze, Todd J. Kohn, Run Zhuang, Simon Wong, Michael D. Bartberger, Zhihua Ma, Daniel C.-H. Lin, Yingcai Wang, George Tonn, Jiwen Jim Liu, Frank Li, Liusheng Zhu, An-Rong Li, Julio C. Medina, Rajiv Sharma
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:15-20
مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Receptors, G-Protein-Coupled, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Pharmacokinetics, In vivo, Free fatty acid receptor 1, Drug Discovery, medicine, Animals, Humans, Imidazole, Structure–activity relationship, Molecular Biology, G protein-coupled receptor, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Drug discovery, Organic Chemistry, Imidazoles, Rats, Macaca fascicularis, 030104 developmental biology, Molecular Medicine
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2
المؤلفون: Lawrence R. McGee, Jeffrey T. Mihalic, Yingcai Wang, Mei-Chu Lo, Jing Zhou, Steven H. Olson, Xiaoqi Chen, Frank Kayser, Jiang Zhu, Ada Chen, Jeffrey Deignan, Jonathan D. Oliner, Alexander M. Long, Daqing Sun, Ming Yu, Xin Huang, Qiuping Ye, Jiwen Jim Liu, Peter Yakowec, Julio C. Medina
المصدر: Bioorganic & Medicinal Chemistry Letters. 24:3782-3785
مصطلحات موضوعية: Models, Molecular, Scaffold, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Acetates, Pharmacology, Crystallography, X-Ray, Biochemistry, Protein–protein interaction, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Humans, Mdm2 p53, Molecular Biology, Piperidones, Sulfonamides, Dose-Response Relationship, Drug, Chemistry, Organic Chemistry, Sulfonamide (medicine), Proto-Oncogene Proteins c-mdm2, Rats, Molecular Medicine, Drug Screening Assays, Antitumor, Tumor Suppressor Protein p53, Protein Binding, medicine.drug
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3
المؤلفون: Jiang Zhu, Tao Osgood, Xin Huang, Anne Y. Saiki, John Eksterowicz, Jiwen Jim Liu, Yosup Rew, Xiaoning Zhao, Qiuping Ye, Steven H. Olson, Julio C. Medina, Michael W. Gribble, David Chow, Jiasheng Fu, Ming Yu, Zhihong Li, Daqing Sun, Jude Canon, Dustin McMinn, Paul L. Shaffer, Xuelei Yan, Yingcai Wang, Brian M. Fox, Mei-Chu Lo, Jonathan D. Oliner, Dongyin Yu, Ada Chen, Michael D. Bartberger, Jing Zhou
المصدر: ACS Medicinal Chemistry Letters. 5:894-899
مصطلحات موضوعية: Antitumor activity, chemistry.chemical_compound, Pharmacokinetics, Chemistry, Stereochemistry, In vivo, Organic Chemistry, Drug Discovery, Substituent, Mdm2 p53, Biochemistry, Combinatorial chemistry
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4
المؤلفون: Run Zhuang, Qi Guo, Xianyun Jiao, Thanhvien Tran, Jonathan B. Houze, Frank Li, Paul John Dransfield, Jane Zhang, Jiwen Jim Liu, Richard V. Connors, Yongli Su, Jian Luo, Julio C. Medina, Marc Vimolratana, Xiaohui Du, Gayathri Swaminath, An-Rong Li, Ming Yu, Liusheng Zhu, Sean P. Brown, Todd J. Kohn, Zhongyu Wang, Yingcai Wang, Daniel C.-H. Lin, Simon Wong
المصدر: ACS Medicinal Chemistry Letters. 5:384-389
مصطلحات موضوعية: Agonist, endocrine system, medicine.drug_class, business.industry, Organic Chemistry, Type 2 diabetes, medicine.disease, Bioinformatics, Biochemistry, Text mining, Pharmacokinetics, In vivo, Free fatty acid receptor 1, Drug Discovery, medicine, Oral glucose tolerance, business
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5
المؤلفون: Karen Siegler, Bei Shan, Mark P. Grillo, Marion Conn, Jiang Zhu, Jian Ken Zhang, Yingcai Wang, Julio C. Medina, Ming Yu, Peter Coward, Frank Kayser, Jiwen Jim Liu
المصدر: Bioorganic & Medicinal Chemistry Letters. 24:156-160
مصطلحات موضوعية: Agonist, Sulfonamides, Dose-Response Relationship, Drug, Molecular Structure, Pyridines, medicine.drug_class, Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Rats, Receptors, G-Protein-Coupled, Structure-Activity Relationship, GPR119, Drug Discovery, Microsomes, Liver, medicine, Animals, Humans, Molecular Medicine, Molecule, Molecular Biology
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6
المؤلفون: Ralph A. DeFronzo, Jiwen Jim Liu, TaeWeon Lee
المصدر: Diabetes
مصطلحات موضوعية: Sodium glucose transporter 2, Blood Glucose, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Biology, Models, Biological, Permeability, Kidney Tubules, Proximal, chemistry.chemical_compound, Pharmacokinetics, Glucosides, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Animals, Humans, Hypoglycemic Agents, Benzhydryl compounds, Benzhydryl Compounds, Sodium-Glucose Transporter 2 Inhibitors, medicine.disease, Renal glucose reabsorption, Endocrinology, Glucose, chemistry, Sodium/Glucose Cotransporter 2, Pharmacodynamics, Perspectives in Diabetes, Kidney tubules
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7
المؤلفون: Matthew L. Brown, Jiwen Jim Liu, Michael G. Johnson, Yingcai Wang, Jay Danao, Alison L. Budelsky, Yongli Su, Tassie L. Collins, Bettina Van Lengerich, Tod Martin, Erika Rickel, H Lucy Tang, Lisa Seitz, Wang Shen, An-Rong Li, Julio C. Medina, Xuemei Wang
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:1686-1689
مصطلحات موضوعية: Dp receptor, Molecular Structure, Stereochemistry, Chemistry, Receptors, Prostaglandin, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Phenylacetic acid, Biochemistry, First generation, Dual (category theory), Inhibitory Concentration 50, chemistry.chemical_compound, HEK293 Cells, Drug Design, Drug Discovery, Humans, Molecular Medicine, Receptors, Immunologic, Receptor, Molecular Biology, Phenylacetates, Protein Binding, G protein-coupled receptor
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8
المؤلفون: Ying Sun, Gayathri Swaminath, Qi Guo, Jiwen Jim Liu, Rajiv Sharma, Sean P. Brown, Julio C. Medina, Zhihua Ma, M.J. Schmitt, Liusheng Zhu, Paul John Dransfield, Daniel C.-H. Lin, Jane Zhang, Simon Wong, Jonathan B. Houze, Yingcai Wang, Run Zhuang, Jian Luo, George Tonn
المصدر: ACS medicinal chemistry letters. 5(5)
مصطلحات موضوعية: Agonist, endocrine system, medicine.medical_specialty, business.industry, medicine.drug_class, Organic Chemistry, Type 2 diabetes, Pharmacology, Phenylpropanoic acid, medicine.disease, Biochemistry, chemistry.chemical_compound, Endocrinology, Postprandial, chemistry, Pharmacokinetics, Free fatty acid receptor 1, Internal medicine, Drug Discovery, medicine, Potency, Hemoglobin, business
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9
المؤلفون: Mark P. Grillo, Karen Siegler, Ming Yu, Jiang Zhu, Peter Coward, Jian Ken Zhang, Frank Kayser, Bei Shan, Yingcai Wang, Julio C. Medina, Marion Conn, Jiwen Jim Liu
المصدر: Bioorganicmedicinal chemistry letters. 24(4)
مصطلحات موضوعية: Oxadiazoles, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Oxadiazole, Ring (chemistry), Biochemistry, Rats, Receptors, G-Protein-Coupled, chemistry.chemical_compound, Macaca fascicularis, Structure-Activity Relationship, Aniline, GPR119, Free fraction, Drug Discovery, Quinolines, Molecular Medicine, Animals, Humans, Molecular Biology
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10
المؤلفون: Frank Li, Xianyun Jiao, Qi Guo, Julio C. Medina, Sean P. Brown, Jian Luo, Daniel C.-H. Lin, Jonathan B. Houze, Lynn Miao, Yingcai Wang, Liusheng Zhu, Tiffany L. Correll, Michael D. Bartberger, Jane Zhang, Run Zhuang, Jiwen Jim Liu, Yongli Su, David Chow, Gayathri Swaminath, An-Rong Li, Paul John Dransfield, Khanh Nguyen, Zhongyu Wang, Simon Wong, Marc Vimolratana, Xiaohui Du, Ming Yu, Thanhvien Tran, Vatee Pattaropong, Annie Kasparian
مصطلحات موضوعية: Agonist, chemistry.chemical_classification, endocrine system, geography, medicine.medical_specialty, geography.geographical_feature_category, medicine.drug_class, business.industry, Organic Chemistry, Pharmacology, Hypoglycemia, Islet, medicine.disease, Biochemistry, Endocrinology, chemistry, In vivo, Internal medicine, Free fatty acid receptor 1, Drug Discovery, medicine, Glucose homeostasis, business, Insulin secretion, Tricyclic
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57cc725905f00876cc74627d7371cf38
https://europepmc.org/articles/PMC4027505/