نتائج البحث - "João Sousa Valente"

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دورية أكاديمية

The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse

المؤلفون: Thomas Pitcher, author¹, João Sousa-Valente, author¹, Marzia Malcangio, author¹

المصدر: Journal of Visualized Experiments. (111)

الإتاحة: http://www.jove.com/video/53746

View record at JoVE Journal

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A historical perspective on the role of sensory nerves in neurogenic inflammation

المؤلفون: João Sousa-Valente, Susan D. Brain

المصدر: Seminars in Immunopathology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b27f62b60b7cdf1fe369c533126874
http://europepmc.org/articles/PMC5960476

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3

Role of TrkA signalling and mast cells in the initiation of osteoarthritis pain in the monoiodoacetate model

المؤلفون: Marzia Malcangio, Raffaele Simeoli, L. Calvo, V. Vacca, João Sousa-Valente, Juan Carlos Arévalo

المصدر: Osteoarthritis and cartilage 26 (2017): 84–94. doi:10.1016/j.joca.2017.08.006
info:cnr-pdr/source/autori:J. Sousa-Valente y, L. Calvo z x, V. Vacca y k, R. Simeoli y, J.C. Arevalo z x, M. Malcangio y/titolo:Role of TrkA signalling and mast cells in the initiation of osteoarthritis pain in the monoiodoacetate model./doi:10.1016%2Fj.joca.2017.08.006/rivista:Osteoarthritis and cartilage/anno:2017/pagina_da:84/pagina_a:94/intervallo_pagine:84–94/volume:26
De Sousa Valente, J, Calvo, L, Vacca, V, Simeoli, R, Arévalo, J C & Malcangio, M 2017, ' Role of TrkA signalling and mast cells in the initiation of osteoarthritis pain in the monoiodoacetate model ', Osteoarthritis and Cartilage . https://doi.org/10.1016/j.joca.2017.08.006, https://doi.org/10.1016/j.joca.2017.08.006

مصطلحات موضوعية: Cartilage, Articular, Male, T-Lymphocytes, Drug Evaluation, Preclinical, microglia, mast cells, Tropomyosin receptor kinase A, Injections, Intra-Articular, chemistry.chemical_compound, 0302 clinical medicine, Orthopedics and Sports Medicine, Mast Cells, Enzyme Inhibitors, Receptor, NGF, Microglia, TrkA, Prostaglandin D2, Osteoarthritis, Knee, Mast cell, Stifle, Lipocalins, Iodoacetic Acid, Up-Regulation, Intramolecular Oxidoreductases, Nociception, medicine.anatomical_structure, Nociceptor, Female, Cartilage Diseases, Biomedical Engineering, 03 medical and health sciences, Rheumatology, medicine, Animals, immunofluorescence, Receptor, trkA, 030203 arthritis & rheumatology, Dose-Response Relationship, Drug, business.industry, Macrophages, astrocytes, Arthritis, Experimental, Mice, Inbred C57BL, osteoarthritis, Disease Models, Animal, nervous system, chemistry, Cyclooxygenase 2, Immunology, Cancer research, immune sytem, Neuron, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56bb4830adb31a1eadf50e45a4744bb
https://doi.org/10.1016/j.joca.2017.08.006

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Full Text via ClinicalKey

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Inflammation of peripheral tissues and injury to peripheral nerves induce differing effects in the expression of the calcium-sensitive N-arachydonoylethanolamine-synthesizing enzyme and related molecules in rat primary sensory neurons

المؤلفون: Jose V. Torres-Perez, Hiren Tailor, Angelika Varga, Ken Mackie, Natsuo Ueda, Kazuhito Tsuboi, Agnes Jenes, João Sousa-Valente, John Wahba, Gábor Jancsó, António Avelino, Péter Sántha, Benjamin F. Cravatt, István Nagy

المصدر: Journal of Comparative Neurology. 525:1778-1796

مصطلحات موضوعية: Male, Nociception, 0301 basic medicine, Cannabinoid receptor, medicine.medical_treatment, Nociceptive Pain, Mice, chemistry.chemical_compound, Transient receptor potential channel, 0302 clinical medicine, Dorsal root ganglion, Fatty acid amide hydrolase, Image Processing, Computer-Assisted, Elméleti orvostudományok, In Situ Hybridization, Fluorescence, Microscopy, Confocal, Reverse Transcriptase Polymerase Chain Reaction, General Neuroscience, Axotomy, Orvostudományok, Anandamide, Immunohistochemistry, medicine.anatomical_structure, lipids (amino acids, peptides, and proteins), psychological phenomena and processes, Signal Transduction, Sensory Receptor Cells, Polyunsaturated Alkamides, Blotting, Western, TRPV1, Arachidonic Acids, Biology, 03 medical and health sciences, Phospholipase D, medicine, Animals, Rats, Wistar, Autocrine signalling, Inflammation, Rats, Mice, Inbred C57BL, Disease Models, Animal, Spinal Nerves, 030104 developmental biology, nervous system, chemistry, Cannabinoid, Neuroscience, 030217 neurology & neurosurgery, Endocannabinoids

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14d899bb10f851220c7bbbeee3cecf3
https://doi.org/10.1002/cne.24154

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Transient receptor potential ion channels in primary sensory neurons as targets for novel analgesics

المؤلفون: Laszlo Urban, João Sousa-Valente, István Nagy, Anna P. Andreou

المصدر: British Journal of Pharmacology. 171:2508-2527

مصطلحات موضوعية: Pharmacology, TRPV4, Transient receptor potential channel, Chemistry, TRPM8, TRPV1, TRPM3, Sensory system, Neuroscience, Transduction (physiology), Sensory Receptor Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::52b23b0fd4c6881d36ceb94b9cf3d302
https://doi.org/10.1111/bph.12532

View record at Wiley

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The monoiodoacetate model of osteoarthritis pain in the mouse

المؤلفون: Thomas Pitcher, João Sousa-Valente, Marzia Malcangio

المصدر: Pitcher, T, Sousa-Valente, J & Malcangio, M 2016, ' The monoiodoacetate model of osteoarthritis pain in the mouse ', Journal of Visualized Experiments, vol. 2016, no. 111, e53746 . https://doi.org/10.3791/53746
Journal of Visualized Experiments : JoVE

مصطلحات موضوعية: Cartilage, Articular, 0301 basic medicine, Knee Joint, chemical model, General Chemical Engineering, Arthritis, Osteoarthritis, weight bearing, Bioinformatics, Injections, Intra-Articular, Weight-Bearing, Mice, OA, Medicine, Enzyme Inhibitors, Behavior, Animal, General Neuroscience, Weight bearing, Osteoarthritis, Knee, Iodoacetic Acid, 3. Good health, in vivo, medicine.anatomical_structure, Allodynia, Hyperalgesia, medicine.symptom, Pain Threshold, medicine.medical_specialty, Pain, General Biochemistry, Genetics and Molecular Biology, Chondrocyte, 03 medical and health sciences, Issue 111, Chondrocytes, Threshold of pain, In vivo, Animals, allodynia, Inflammation, Behavior, General Immunology and Microbiology, Chemical model, behavior, business.industry, Cartilage, medicine.disease, Arthritis, Experimental, Surgery, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6256a6a375eee96a6e1d43a7019a0860
https://kclpure.kcl.ac.uk/en/publications/77321036-233b-4c3a-9f1b-33b72eb5f5b9

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Anandamide produced by Ca2+-insensitive enzymes induces excitation in primary sensory neurons

المؤلفون: Vincenzo Di Marzo, László Csernoch, Laki Buluwela, Srikumaran Selvarajah, Agnes Jenes, István Nagy, Fabiana Piscitelli, Fiona Kyle, Anthony H. Taylor, Jonothan Austin, Timothy H. Marczylo, Jie Chen, Anna P. Andreou, John P. M. White, João Sousa-Valente, Susan D. Brain, Mohammed Yaqoob, Angelika Varga

المصدر: Pflügers Archiv 466 (2014): 1421–1435. doi:10.1007/s00424-013-1360-7
info:cnr-pdr/source/autori:Varga, Angelika; Jenes, Agnes; Marczylo, Timothy H.; Sousa-Valente, Joao; Chen, Jie; Austin, Jonothan; Selvarajah, Srikumaran; Piscitelli, Fabiana; Andreou, Anna P.; Taylor, Anthony H.; Kyle, Fiona; Yaqoob, Mohammed; Brain, Sue; White, John P. M.; Csernoch, Laszlo; Di Marzo, Vincenzo; Buluwela, Laki; Nagy, Istvan/titolo:Anandamide produced by Ca2+-insensitive enzymes induces excitation in primary sensory neurons/doi:10.1007%2Fs00424-013-1360-7/rivista:Pflügers Archiv/anno:2014/pagina_da:1421/pagina_a:1435/intervallo_pagine:1421–1435/volume:466

مصطلحات موضوعية: Male, Cannabinoid receptor, Sensory Receptor Cells, Polyunsaturated Alkamides, Physiology, medicine.medical_treatment, Clinical Biochemistry, TRPV1, Pain, Action Potentials, TRPV Cation Channels, Sensory system, Arachidonic Acids, Inhibitory postsynaptic potential, Rats, Sprague-Dawley, Mice, chemistry.chemical_compound, Transient receptor potential channel, Ganglia, Spinal, Physiology (medical), medicine, Animals, Group IB Phospholipases A2, Elméleti orvostudományok, Cells, Cultured, Phosphoric Diester Hydrolases, Phosphatidylethanolamines, Protein Tyrosine Phosphatase, Non-Receptor Type 22, Orvostudományok, Anandamide, CB1, Nociceptive processing, Rats, Cell biology, Mice, Inbred C57BL, chemistry, Excitatory postsynaptic potential, Calcium, lipids (amino acids, peptides, and proteins), Cannabinoid, Lysophospholipase, Neuroscience, Endocannabinoids