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1
المؤلفون: Robert Godemann, Kathleen Knüppel, Christian A.G.N. Montalbetti, Stefan Steinbacher, Myron Smith, Lawren C. Wu, Swathi Sujatha-Bhaskar, Jianwen Feng, Maureen Beresini, Jacob Z. Chen, Christine Everett, Pawan Bir Kohli, Susan Krüger, Joachim Kraemer, David A. Roberts, Sarah G. Hymowitz, Ryan Takahashi, Hans Brightbill, Paul A. McEwan, Nobuhiko Kayagaki, Yamin Zhang, Pui Loke, Georgette Castanedo, Charles Eigenbrot, Hai-Feng Cui, Nicole Blaquiere, Steven T. Staben, Brandon J. Bravo, Adam R. Johnson, Emily B. Gogol, Xiaolu Wang
المصدر: Journal of Medicinal Chemistry. 60:627-640
مصطلحات موضوعية: 0301 basic medicine, P50, High selectivity, Active Transport, Cell Nucleus, Protein Serine-Threonine Kinases, Heterocyclic Compounds, 4 or More Rings, Nf κb inducing kinase, Mice, 03 medical and health sciences, Dogs, 0302 clinical medicine, NF-kappa B p52 Subunit, Drug Discovery, Animals, Humans, Oxazoles, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Phosphoinositide-3 Kinase Inhibitors, Cell Nucleus, chemistry.chemical_classification, Binding Sites, Phosphoinositide 3-kinase, biology, Kinase, Imidazoles, NF-kappa B p50 Subunit, Isoxazoles, Heterocyclic Compounds, Bridged-Ring, Oxazepines, HEK293 Cells, 030104 developmental biology, chemistry, Biochemistry, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Structure based, HeLa Cells, Signal Transduction, Tricyclic
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2
المؤلفون: Matvey E. Lukashev, Victor Hong, Hernan Cuervo, Ping Jin, Douglas Marcotte, Alexey Lugovskoy, Valérie Vivat, C Hession, Deping Wang, Joachim Kraemer, Jean-Christophe Hus, Chris Bergeron, Dominique Roecklin, Weike Zeng, Malgorzata M. Vecchi, Dirk Winkler, Istvan J. Enyedy, Cédric Atmanene, Laura Silvian, Andres McKenzie, Jianhua Chao
المصدر: Bioorganic & Medicinal Chemistry. 21:4011-4019
مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, NF-E2-Related Factor 2, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Small Molecule Libraries, Structure-Activity Relationship, Transcription (biology), Drug Discovery, Luciferase, Molecular Biology, Transcription factor, Reporter gene, Kelch-Like ECH-Associated Protein 1, Chemistry, Organic Chemistry, Intracellular Signaling Peptides and Proteins, KEAP1, Small molecule, Protein Structure, Tertiary, Biophysics, Thermodynamics, Molecular Medicine, Carrier Proteins, Protein Binding, Cysteine
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3
المؤلفون: Henry Johannes Greten, Serkan Sertel, Ingo Baumann, Thomas Efferth, Hans-Joachim Kraemer, Peter K. Plinkert
المصدر: The Open Otorhinolaryngology Journal. 4:62-67
مصطلحات موضوعية: medicine.medical_specialty, Quality of life, business.industry, MEDLINE, medicine, Complementary therapy, In patient, Traditional Chinese medicine, Intensive care medicine, business, humanities, Western medicine, Scientific evidence
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8d4ca5a3b51f918ed2492ccf472fe3f8
https://doi.org/10.2174/1874428101004010062 -
4
المؤلفون: Hans-Joachim Kraemer, Henning Breithaupt
المصدر: Journal of Chromatography B: Biomedical Sciences and Applications. 710:191-204
مصطلحات موضوعية: Detection limit, Reaction rate, chemistry.chemical_compound, Order of reaction, Chromatography, Chemistry, Analytical procedures, General Chemistry, Solid phase extraction, Derivatization, High-performance liquid chromatography, Quantitative analysis (chemistry)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8456185b6bed8c28dddc6ef3c5f59383
https://doi.org/10.1016/s0378-4347(98)00093-0 -
5
المؤلفون: Hans-Joachim Kraemer, Ulrich Feltkamp, Henning Breithaupt
المصدر: Journal of Chromatography B: Biomedical Sciences and Applications. 706:319-328
مصطلحات موضوعية: Chromatography, Chemistry, Metabolite, Extraction (chemistry), General Chemistry, Reversed-phase chromatography, Pyrazinamide, High-performance liquid chromatography, chemistry.chemical_compound, Pyrazinoic acid, medicine, Uric acid, Solid phase extraction, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::110276a4c560d041b632e67d04e51f52
https://doi.org/10.1016/s0378-4347(97)00519-7 -
6
المؤلفون: Rosemary Maghames, Xiaolu Wang, Daniel F. Ortwine, Alexander Heifetz, Colin H. MacKinnon, J Dines, Darshan G. Vaidya, Marya Liimatta, Kevin Lau, Adam R. Johnson, Joachim Kraemer, Susanne Kruger, Allan Jaochico, Charles Eigenbrot, Steven Mark Bromidge, Steven Shia, Yuan Chen, Xiao Ding, Zhonghua Pei, Justin Ly, Lawren C. Wu, Yolanda Pérez-Fuertes, Jason Burch, Giancarlo Trani, Daniel B. Stein, Christian A.G.N. Montalbetti, Thomas M. Krülle
المصدر: Bioorganicmedicinal chemistry letters. 23(23)
مصطلحات موضوعية: Models, Molecular, Cellular activity, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Anti-inflammatory, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Interleukin-2-Inducible T-Cell Kinase, Drug Discovery, medicine, Animals, Humans, Benzothiazoles, Molecular Biology, Kinase, Organic Chemistry, Protein-Tyrosine Kinases, Inhibitory potency, Benzothiazole, chemistry, Drug Design, Molecular Medicine, Structure based, Tyrosine kinase, Signal Transduction
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7
المؤلفون: Myron A. Smith, Marion Biniszkiewicz, David James Hallett, John Barker, Jenny R. Dod, James Madden, Joachim Kraemer, Robert Godemann, Jane Dannow Dyekjaer, Thomas Hesterkamp
المصدر: Bioorganicmedicinal chemistry letters. 20(17)
مصطلحات موضوعية: Models, Molecular, 2-aminobenzimidazole, Drug discovery, Stereochemistry, Chemistry, Memapsin-2, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Computational biology, Biochemistry, Structure-Activity Relationship, Fragment (logic), Drug Discovery, Molecular Medicine, Aspartic Acid Endopeptidases, Humans, Protease Inhibitors, Amyloid Precursor Protein Secretases, Aspartic Endopeptidases, Molecular Biology
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8
المؤلفون: Dirk Winkler, Jan Kahmann, Sabine Schaertl, Joachim Kraemer, Oliver Keminer, Osamu Ichihara, Dirk Ullmann, Ina Sternberger, Christoph Scheich, Thomas Hesterkamp, Mark Whittaker, Joern Jungmann
المصدر: Combinatorial chemistryhigh throughput screening. 12(7)
مصطلحات موضوعية: Stereochemistry, Chemistry, Tumor Necrosis Factor-alpha, Organic Chemistry, Intracellular Signaling Peptides and Proteins, General Medicine, Nuclear magnetic resonance spectroscopy, Protein Serine-Threonine Kinases, Peptide Fragments, Computer Science Applications, Fragment (logic), Biochemistry, Drug Discovery, Humans, Biological Assay, MAPKAP Kinase 2, Signal transduction, Enzyme Inhibitors, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5951e8cebcfa2f099624c807c533438
https://pubmed.ncbi.nlm.nih.gov/19531016 -
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المصدر: ChemInform. 36
مصطلحات موضوعية: Biochemistry, Chemistry, Malassezia furfur, Tryptophan, General Medicine, Yeast
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10
المؤلفون: Neil Benson, Joachim Kraemer, Penny A. Wright, Eloisa Lopez-Calle, Richard Bethell, Michael Busch, Phillip Gribbon, Thomas Mander, Dirk Winkler, Helen Boyd
المصدر: Journal of biomolecular screening. 7(5)
مصطلحات موضوعية: 0301 basic medicine, Amino Acid Motifs, Analytical chemistry, Peptide, Fluorescence Polarization, MAP Kinase Kinase 7, Ligands, 01 natural sciences, Biochemistry, Sensitivity and Specificity, Analytical Chemistry, MAP2K7, 03 medical and health sciences, Inhibitory Concentration 50, Adenosine Triphosphate, Antibody Specificity, Mitogen-Activated Protein Kinase 10, Mitogen-Activated Protein Kinase 9, Magnesium, Mitogen-Activated Protein Kinase 8, Enzyme Inhibitors, Phosphorylation, Protein kinase A, Anisotropy, chemistry.chemical_classification, Mitogen-Activated Protein Kinase Kinases, Chromatography, biology, Kinase, Chemistry, Rhodamines, Microchemistry, Reproducibility of Results, Protein-Tyrosine Kinases, Peptide Fragments, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Kinetics, 030104 developmental biology, Mitogen-activated protein kinase, Reagent, biology.protein, Linear Models, Molecular Medicine, Mitogen-Activated Protein Kinases, Fluorescence anisotropy, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4921e801a902e3d10df1c21c66ba89
https://pubmed.ncbi.nlm.nih.gov/14599357