المؤلفون: Nadine Ruderisch, Daniel Schlatter, Andreas Kuglstatter, Wolfgang Guba, Sylwia Huber, Carlo Cusulin, Jörg Benz, Arne Christian Rufer, Joerg Hoernschemeyer, Christophe Schweitzer, Tina Bülau, Achim Gärtner, Eike Hoffmann, Jens Niewoehner, Christoph Patsch, Karlheinz Baumann, Hansruedi Loetscher, Eric Kitas, Per-Ola Freskgård

المصدر: EBioMedicine, Vol 24, Iss C, Pp 76-92 (2017)

مصطلحات موضوعية: BACE1, Alzheimer's disease, Blood brain barrier, CNS delivery, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396417303511; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/316ddf067d1746b19366ae2a8f354fcb

المؤلفون: Paola Favuzza, Elena Guffart, Marco Tamborrini, Bianca Scherer, Anita M Dreyer, Arne C Rufer, Johannes Erny, Joerg Hoernschemeyer, Ralf Thoma, Georg Schmid, Bernard Gsell, Araceli Lamelas, Joerg Benz, Catherine Joseph, Hugues Matile, Gerd Pluschke, Markus G Rudolph

المصدر: eLife, Vol 6 (2017)

مصطلحات موضوعية: CyRPA, Malaria vaccine candidate, sialidase, crystal structure, β-propeller, invasion inhibitory antibody, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/20383; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/020ed0eebb0d43a8aea76fd5a4619c3b

المؤلفون: Mihaela Dragusin, Cristian Gurgui, Günter Schwarzmann, Joerg Hoernschemeyer, Gerhild van Echten-Deckert

المصدر: Journal of Lipid Research, Vol 44, Iss 9, Pp 1772-1779 (2003)

مصطلحات موضوعية: primary cultured neurons, neuroblastoma cells B104, Swiss 3T3 cells, l-threo-sphinganine, ceramide, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520337421; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/e546193b821c442faf9db6b30e0cde2f

المؤلفون: Tom Atherton, Carl Heatherington, Ulrike Rieder, Robert Peter, Thomas De Vijlder, Rainer Wechselberger, Francis Ring, Joerg Hoernschemeyer, Jessica A. Stolee, David Benstead, Ayman Charaf, Hong Jiang, Daniel C. Capaldi, Nadim Akhtar

المصدر: Nucleic Acid Therapeutics. 30:249-264

مصطلحات موضوعية: 0301 basic medicine, Drug, Risk analysis, Computer science, media_common.quotation_subject, Oligonucleotides, Computational biology, Identity testing, Oligonucleotide synthesis, Risk Assessment, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Genetics, Humans, Molecular Biology, media_common, Oligonucleotide, Sequence Analysis, DNA, Mass measurement, 030104 developmental biology, Pharmaceutical Preparations, 030220 oncology & carcinogenesis, Identity (object-oriented programming), Molecular Medicine, Risk assessment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25dac9cb2bebc07dd39c91980bc3e71
https://doi.org/10.1089/nat.2020.0878

المؤلفون: Christophe Schweitzer, Christoph Patsch, Joerg Hoernschemeyer, Eric A. Kitas, Eike Hoffmann, Jens Niewoehner, Nadine Ruderisch, Karlheinz Baumann, Sylwia Huber, Per-Ola Freskgard, Hansruedi Loetscher, Jörg Benz, Achim Gärtner, Arne C. Rufer, Carlo Cusulin, Tina Bülau, Andreas Kuglstatter, Wolfgang Guba, Daniel Schlatter

المصدر: EBioMedicine
EBioMedicine, Vol 24, Iss C, Pp 76-92 (2017)

مصطلحات موضوعية: 0301 basic medicine, lcsh:Medicine, Peptide, Pharmacology, Blood–brain barrier, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, Sortase, Catalytic Domain, Receptors, Transferrin, mental disorders, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Potency, chemistry.chemical_classification, lcsh:R5-920, Amyloid beta-Peptides, Dose-Response Relationship, Drug, biology, CNS delivery, lcsh:R, Brain, BACE1, General Medicine, Alzheimer's disease, Small molecule, Peptide Fragments, 030104 developmental biology, medicine.anatomical_structure, chemistry, Blood brain barrier, Blood-Brain Barrier, biology.protein, Administration, Intravenous, Amyloid Precursor Protein Secretases, Antibody, Lipid modification, lcsh:Medicine (General), Amyloid precursor protein secretase, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ad5bf832352c9060ecd331ea0b6c7b
https://doi.org/10.1016/j.ebiom.2017.09.004

المؤلفون: Paula P Navarro, Amanda J Lewis, Tim Moors, Jürgen Hench, Wilma D.J. van de Berg, Jing Wang, Vincenzo Bonifati, Andreas Staempfli, Markus Britschgi, Annemieke J.M. Rozemuller, Frederik Großerüschkamp, Henning Stahlberg, Stephan Frank, Evelien Huisman, Klaus Gerwert, Daniel Niedieker, Wilfred F. J. van IJcken, Yvonne de Gier, Rosmarie Sütterlin, Gabriel Schweighauser, Angela Ingrassia, Kenneth N. Goldie, Joerg Hoernschemeyer, Anne De Paepe, Sarah H Shahmoradian, Matthias E. Lauer, Johannes Erny, Alexandra Graff-Meyer, Christel Genoud, Marialuisa Quadri, Bernd Bohrmann, Daniel Castaño-Díez, Samir F. El-Mashtoly

المساهمون: Clinical Genetics, Cell biology, Anatomy and neurosciences, VU University medical center, Pathology, Amsterdam Neuroscience - Neurodegeneration

المصدر: Shahmoradian, S H, Lewis, A J, Genoud, C, Hench, J R, Moors, T E, Navarro, P P, Castaño-Díez, D, Schweighauser, G, Graff-Meyer, A, Goldie, K N, Sütterlin, R, Huisman, E, Ingrassia, A, Gier, Y D, Rozemuller, A J M, Wang, J, Paepe, A D, Erny, J, Staempfli, A, Hoernschemeyer, J, Großerüschkamp, F, Niedieker, D, el-Mashtoly, S F, Quadri, M, van IJcken, W F J, Bonifati, V, Gerwert, K, Bohrmann, B, Frank, S, Britschgi, M, Stahlberg, H, van de Berg, W D J & Lauer, M E 2019, ' Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes ', Nature Neuroscience, vol. 22, no. 7, pp. 1099-1109 . https://doi.org/10.1038/s41593-019-0423-2
Nature Neuroscience, 22(7), 1099-+. Nature Publishing Group
Nature Neuroscience, 22(7), 1099-1109. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Lewy Body Disease, Parkinson's disease, Biology, Hippocampus, Pathogenesis, 03 medical and health sciences, Membrane Lipids, 0302 clinical medicine, Imaging, Three-Dimensional, Alzheimer Disease, Mesencephalon, Organelle, Lipidomics, Exome Sequencing, medicine, Humans, Organelles, Microscopy, Confocal, General Neuroscience, STED microscopy, Parkinson Disease, Human brain, Intracellular Membranes, Compartmentalization (fire protection), medicine.disease, Substantia Nigra, Microscopy, Electron, 030104 developmental biology, medicine.anatomical_structure, Microscopy, Fluorescence, Ultrastructure, alpha-Synuclein, Lewy Bodies, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b1dc002c6518905c4185595a0f3b06
https://research.vumc.nl/en/publications/06f8f039-13aa-44ee-a512-b049e4ba1194

المؤلفون: Gerhard Becker, Johanna Poecheim, Kirsten Storch, Miriam Printz, Joerg Hoernschemeyer, Kirsten Graeser

المصدر: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 129

مصطلحات موضوعية: 0301 basic medicine, Drug Carriers, Acetylgalactosamine, 030102 biochemistry & molecular biology, Oligonucleotide, Chemistry, Drug Compounding, Oligonucleotides, Pharmaceutical Science, Sterilization, General Medicine, Hydrogen-Ion Concentration, Combinatorial chemistry, Excipients, Solutions, 03 medical and health sciences, 030104 developmental biology, Drug Stability, Gamma Rays, Single stranded oligonucleotides, Drug product, Degradation (geology), Locked nucleic acid, Biotechnology, Gamma irradiation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264186fb391fe47dd86b17e77cc69807
https://pubmed.ncbi.nlm.nih.gov/29802983

المؤلفون: Sarah H. Shahmoradian, Amanda J. Lewis, Christel Genoud, Jürgen Hench, Tim Moors, Paula P. Navarro, Daniel Castaño-Díez, Gabriel Schweighauser, Alexandra Graff-Meyer, Kenneth N. Goldie, Rosmarie Sütterlin, Evelien Huisman, Angela Ingrassia, Yvonne de Gier, Annemieke J.M. Rozemuller, Jing Wang, Anne De Paepe, Johannes Erny, Andreas Staempfli, Joerg Hoernschemeyer, Frederik Großerüschkamp, Daniel Niedieker, Samir F. El-Mashtoly, Marialuisa Quadri, Wilfred F.J. van IJcken, Vincenzo Bonifati, Klaus Gerwert, Bernd Bohrmann, Stephan Frank, Markus Britschgi, Henning Stahlberg, Wilma D. J. van de Berg, Matthias E. Lauer

المساهمون: Anatomy and neurosciences, Amsterdam Neuroscience - Neurodegeneration

المصدر: Biorxiv. Cold Spring Harbor Laboratory Press
Biorxiv
Sharamoradian, S, Britschgi, M, Stahlberg, H, van de Berg, WDJ & Lauer, M 2017, ' Lewy pathology in Parkinson's disease consists of a crowded organellar membranous medley ', Biorxiv .

مصطلحات موضوعية: 0303 health sciences, Pathology, medicine.medical_specialty, Parkinson's disease, Neurite, Anatomy, Disease, Mitochondrion, Compartmentalization (psychology), Biology, medicine.disease, 3. Good health, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, medicine, Ultrastructure, Cytoskeleton, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a478964199a15d6cd71c877c3585f2
https://doi.org/10.1101/137976

المؤلفون: Araceli Lamelas, Hugues Matile, Anita M Dreyer, Markus G. Rudolph, Joerg Hoernschemeyer, Bernard Gsell, Gerd Pluschke, Paola Favuzza, Johannes Erny, Ralf Thoma, Joerg Benz, Georg Schmid, Arne C. Rufer, Marco Tamborrini, Catherine Joseph, Elena Guffart, Bianca Scherer

المصدر: eLife, Vol 6 (2017)
eLife

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, crystal structure, Protein Conformation, QH301-705.5, Science, 030106 microbiology, Protozoan Proteins, Antibodies, Protozoan, Antigens, Protozoan, Crystallography, X-Ray, General Biochemistry, Genetics and Molecular Biology, Epitope, P. falciparum, 03 medical and health sciences, CyRPA, Immune system, Antigen, Malaria Vaccines, parasitic diseases, medicine, Biology (General), Microbiology and Infectious Disease, General Immunology and Microbiology, biology, Malaria vaccine, sialidase, General Neuroscience, Plasmodium falciparum, General Medicine, Biophysics and Structural Biology, medicine.disease, biology.organism_classification, β-propeller, Virology, Malaria vaccine candidate, 030104 developmental biology, Infectious disease (medical specialty), Immunology, biology.protein, invasion inhibitory antibody, Medicine, Antibody, Malaria, Research Article, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d89eb67219070cda2fda203743e4f3a2
https://doi.org/10.7554/elife.20383

المؤلفون: Gerd Pluschke, Paola Favuzza, Ralf Thoma, Araceli Lamelas, Catherine Joseph, Elena Guffart, Bianca Scherer, Anita M Dreyer, Georg Schmid, Joerg Benz, Hugues Matile, Marco Tamborrini, Johannes Erny, Markus G. Rudolph, Joerg Hoernschemeyer, Arne C. Rufer, Bernard Gsell

مصطلحات موضوعية: biology, Antigen, Malaria vaccine, biology.protein, Parasite hosting, Antibody, Inhibitory postsynaptic potential, Virology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::73d6cef6ac0a8d0b4c5ebbf0a1015138
https://doi.org/10.7554/elife.20383.037