المؤلفون: Stefan Christen, Doriane Lorendeau, Roberta Schmieder, Dorien Broekaert, Kristine Metzger, Koen Veys, Ilaria Elia, Joerg Martin Buescher, Martin Franz Orth, Shawn Michael Davidson, Thomas Georg Philipp Grünewald, Katrien De Bock, Sarah-Maria Fendt

المصدر: Cell Reports, Vol 17, Iss 3, Pp 837-848 (2016)

مصطلحات موضوعية: pyruvate carboxylase, mitochondrial pyruvate concentration, lung metastasis, breast cancer, TCA cycle anaplerosis, microenvironment, glycolytic metabolism, cancer metabolism, 13C tracer analysis, pyruvate metabolism, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124716312815; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/5ab2f0b51c034757927446c1f559236f

المؤلفون: Sarah‐Maria Fendt, Joerg Martin Buescher, Florian Rudroff, Paola Picotti, Nicola Zamboni, Uwe Sauer

المصدر: Molecular Systems Biology, Vol 6, Iss 1, Pp n/a-n/a (2010)

مصطلحات موضوعية: design principle, metabolic network, metabolomics, proteomics, transcriptome, Biology (General), QH301-705.5, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1744-4292

URL الوصول: https://doaj.org/article/4381c931a8a34df2be583626db6bcb0d

المؤلفون: Stefan Rapprich, Michael Krohn, Andreas Hochheimer, Joerg Martin Buescher, Torsten Ertongur-Fauth

المصدر: Experimental Dermatology. 23:825-831

مصطلحات موضوعية: Gene isoform, medicine.medical_specialty, Molecular Sequence Data, chemistry.chemical_element, Dermatology, Eccrine Glands, Biology, Calcium, Biochemistry, SWEAT, Chlorides, Chloride Channels, Internal medicine, Sweat gland, Gene expression, medicine, Humans, Secretion, Amino Acid Sequence, Eccrine sweat gland, Sweat, Molecular Biology, Anoctamin-1, Skin, integumentary system, Alternative splicing, Epithelial Cells, Neoplasm Proteins, Protein Structure, Tertiary, Sweat Glands, Cell biology, Alternative Splicing, Endocrinology, medicine.anatomical_structure, chemistry, Protein Multimerization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c8b4c90139eb0fb5ff673db9f5539d
https://doi.org/10.1111/exd.12543

المؤلفون: Koen Veys, Thomas G. P. Grunewald, Kristine Metzger, Sarah-Maria Fendt, Ilaria Elia, Dorien Broekaert, Doriane Lorendeau, Martin F. Orth, Shawn M. Davidson, Joerg Martin Buescher, Katrien De Bock, Roberta Schmieder, Stefan Christen

المساهمون: Koch Institute for Integrative Cancer Research at MIT, Davidson, Shawn Michael

المصدر: Elsevier
Cell Reports, Vol 17, Iss 3, Pp 837-848 (2016)
Cell Reports, 17 (3)

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Metabolite, cancer metabolism, chemistry.chemical_compound, Adenosine Triphosphate, Cytosol, Pyruvic Acid, Tumor Microenvironment, Citrate synthase, lcsh:QH301-705.5, chemistry.chemical_classification, Carbon Isotopes, biology, lung metastasis, Tricarboxylic acid, Pyruvate carboxylase, Mitochondria, pyruvate carboxylase, mitochondrial pyruvate concentration, breast cancer, TCA cycle anaplerosis, microenvironment, glycolytic metabolism, 13C tracer analysis, pyruvate metabolism, Adenosine Diphosphate, medicine.anatomical_structure, Biochemistry, Isotope Labeling, Female, Citric Acid Cycle, Breast Neoplasms, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Breast cancer, Acetyl Coenzyme A, Cell Line, Tumor, medicine, Humans, Enzyme kinetics, Pyruvate Carboxylase, Lung, medicine.disease, Cell Compartmentation, Glutamine, 030104 developmental biology, lcsh:Biology (General), chemistry, biology.protein

وصف الملف: Print; application/pdf; application/application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460eaf62ed2d14714bf115ae73b27d71
https://pubmed.ncbi.nlm.nih.gov/27732858

المؤلفون: Claus Hultschig, Patrick Veiga, Edda Klipp, Michael Hecker, Annette Hansen, Etienne Dervyn, Elena Bidnenko, Philippe Noirot, Bernd Hessling, Emma L. Denham, Markus Uhr, Susanne Pohl, Ludovic Le Chat, Joerg Martin Buescher, Benno Schwikowski, Hanne Østergaard Jarmer, Jan Muntel, Bernd Rinn, Pierre Nicolas, Jan Maarten van Dijl, Roelco J. Kleijn, Simon Rasmussen, Colin R. Harwood, Samuel Drulhe, Liza Felicori, Jörg Stelling, Sean Walsh, Kevin M. Devine, Frank Rügheimer, Nathalie Pigeonneau, Dörte Becher, Mark J. Fogg, Peter J. Lewis, Eric Botella, Geoff Doherty, Philippe Bessières, Ulrike Mäder, Marc Schaffer, Sjouke Piersma, Stéphane Aymerich, Anthony J. Wilkinson, Anne Goelzer, Julian Schnidder, F. Molina, Wolfram Liebermeister, Uwe Sauer, Sabine Peres, Sebastian Hubner, Matthieu Jules, François Lecointe, Aurélie Leduc

المساهمون: Institute of Molecular Systems Biology [Zurich], Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology in Zürich [Zürich] (ETH Zürich), Theoretical Biophysics [Berlin], Humboldt Universität zu Berlin, MICrobiologie de l'ALImentation au Service de la Santé (MICALIS), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, Department of Biosystems Science and Engineering [ETH Zürich] (D-BSSE), Institut für Mikrobiologie - Institute for Microbiology, Universität Greifswald - University of Greifswald, Smurfit Institute of Genetics, Trinity College Dublin, Unité Mathématique, Informatique et Génome (MIG), Institut National de la Recherche Agronomique (INRA), Department of Medical Microbiology, University of Groningen [Groningen], Biologie systémique - Systems Biology, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), School of Environmental and Life Sciences, Newcastle University [Newcastle], Sysdiag CNRS Bio-Rad UMR 3145, Cap Delta/Parc Euromédecine, Centre National de la Recherche Scientifique (CNRS), York Structural Biology Laboratory, Department of Chemistry, University of York [York, UK], Centre for Bacterial Cell Biology, Institute of Cell and Molecular Biosciences, Center for Information Sciences and Databases - Department of Biosystems Science and Engineering, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark [Lyngby] (DTU), Centre for Bacterial Cell Biology, Institute, of Cell and Molecular Biosciences, University of Northumbria at Newcastle [United Kingdom], Institute Molecular Systems Biology, Center for Information Sciences and Databases, Department of Biosystems Science and Engineering, Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), Humboldt-Universität zu Berlin, Departement Erdwissenschaften [ETH Zürich] (D-ERDW), Humboldt University Of Berlin, Genes and Behavior Department [Göttingen], Max Planck Institute for Biophysical Chemistry (MPI-BPC), Max-Planck-Gesellschaft-Max-Planck-Gesellschaft, Ernst-Moritz-Arndt-Universität Greifswald, Interfaculty Institute for Genetics and Functional Genomics, Biosynthèse des Signaux Peptidiques [IBPS] (IBPS-BIOSIPE), Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University Medical Center Groningen, Partenaires INRAE, Biologie Systémique, Institut Pasteur [Paris] (IP), Unité Mathématique Informatique et Génome (MIG), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Sysdiag-Modélisation et Ingénierie des Systèmes Complexes Biologiques pour le Diagnostic (SysDiag ), BIO-RAD-Centre National de la Recherche Scientifique (CNRS), This work was funded through the European Commission 7th Framework project BaSys Bio (LSHG-CT-2006-037469), coordinated by P. Noirot, the Department of Education, Science and Training (CG110055),and the National Health and Medical Research Council (455646), Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Danmarks Tekniske Universitet = Technical University of Denmark (DTU), Faculteit Medische Wetenschappen/UMCG, Microbes in Health and Disease (MHD), Translational Immunology Groningen (TRIGR)

المصدر: Science
Science, American Association for the Advancement of Science, 2012, 335 (6072), pp.1099-1103. ⟨10.1126/science.1206871⟩
Science, 2012, 335 (6072), pp. 1099-1103. ⟨10.1126/science.1206871⟩
Science, 2012, 335 (6072), pp.1099-1103. ⟨10.1126/science.1206871⟩
Science, 335(6072), 1099-1103. AMER ASSOC ADVANCEMENT SCIENCE

مصطلحات موضوعية: carbon metabolism, Transcription, Genetic, Operon, [SDV]Life Sciences [q-bio], Gene regulatory network, Malates, Bacillus subtilis, Transcriptional regulation, Gene Regulatory Networks, bacteria, Promoter Regions, Genetic, bacterie, 0303 health sciences, Multidisciplinary, TRANSCRIPTIONAL REGULATION, regulation, Adaptation, Physiological, Biochemistry, ESCHERICHIA-COLI, Data Interpretation, Statistical, Metabolome, Algorithms, Metabolic Networks and Pathways, Computational biology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, Models, Biological, 03 medical and health sciences, Metabolomics, Bacterial Proteins, SYSTEMS, metabolisme du carbone, Computer Simulation, YEAST, RECONSTRUCTION, Reorganization, Gene, 030304 developmental biology, COMPLEXITY, 030306 microbiology, BIOLOGIE, Gene Expression Regulation, Bacterial, BIOLOGIE MOLECULAIRE, biology.organism_classification, Glucose, Adaptation, STARVATION, Genome, Bacterial, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec31dfbe5e60ff7fce5721e46e4e5360
https://research.rug.nl/en/publications/43e8904b-4689-4bfe-aa20-09645cc7a615

المؤلفون: Edward M. Driggers, Joerg Martin Buescher

المصدر: Cancer & Metabolism

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Systems biology, Metabolic network, Genomics, Context (language use), Review, Biology, computer.software_genre, 03 medical and health sciences, Leverage (statistics), Metabolomics, Transcriptomics, Cancer, Omics, Data science, Algorithm, Psychiatry and Mental health, 030104 developmental biology, Cellular physiology, Data integration, computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183e77eaee82a1e51bb71a25c8bb8373
https://pubmed.ncbi.nlm.nih.gov/26900468

المؤلفون: Clary B. Clish, Craig R. Malloy, Alexei Vazquez, Sophia Y. Lunt, Karsten Hiller, Emmanuelle J. Meuillet, Richard G. Kibbey, Sarah-Maria Fendt, Jason W. Locasale, Alec C. Kimmelman, Daniel A. Tennant, Katharina Nöh, Joerg Martin Buescher, Joshua D. Rabinowitz, Bart Ghesquière, Ralph J. DeBerardinis, Oliver D. K. Maddocks, Christian Frezza, Christoph Wittmann, Julie St-Pierre, Joshua Munger, Christian M. Metallo, Karen H. Vousden, Jurre J. Kamphorst, Uwe Sauer, Shawn C. Burgess, Markus Ralser, Jamey D. Young, Olivier Feron, Laszlo G. Boros, Nicola Zamboni, Maciek R. Antoniewicz, Matthew G. Vander Heiden, Gregory Stephanopoulos, Russell G. Jones, Henri Brunengraber, Eyal Gottlieb

المساهمون: Massachusetts Institute of Technology. Department of Chemical Engineering, Stephanopoulos, Gregory

المصدر: PMC
Current opinion in biotechnology, 34, 189-201. England (2015).

مصطلحات موضوعية: Technology, Cell Survival, Metabolite, Biomedical Engineering, Bioengineering, Biology, Biochemistry, biophysics & molecular biology [F05] [Life sciences], Key issues, Article, Isotope Labeling/methods, chemistry.chemical_compound, Engineering, Animals, Humans, Biochimie, biophysique & biologie moléculaire [F05] [Sciences du vivant], Cell survival, Nutrition, Carbon Isotopes, Isotopic tracer, Biological Sciences, chemistry, Biochemistry, Isotope Labeling, Carbon Isotopes/metabolism, Generic health relevance, Flux (metabolism), Metabolic Networks and Pathways, Biotechnology

وصف الملف: Print-Electronic; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af452e23389c6c928f4708a729806ee
https://lirias.kuleuven.be/handle/123456789/488416

المؤلفون: Joerg Martin Buescher, Argyrios Margaritis

المصدر: Critical Reviews in Biotechnology. 27:1-19

مصطلحات موضوعية: Drug Industry, Biomedical Technology, Food technology, engineering.material, Models, Biological, Applied Microbiology and Biotechnology, chemistry.chemical_compound, Biopolymers, Biosynthesis, Food Industry, Particle Size, Bacillaceae, Drug Carriers, Molecular Structure, business.industry, Polyglutamic acid, Stereoisomerism, General Medicine, Biopharmaceutical, Polyglutamic Acid, chemistry, Biochemistry, Genes, Bacterial, Food products, Drug delivery, engineering, Food Technology, Nanoparticles, Biopolymer, Drug carrier, business, Forecasting, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b79b00921a3c4ef9d278aafc638a355
https://doi.org/10.1080/07388550601166458

المؤلفون: Joerg Martin Buescher, Uwe Sauer, Hannes Link

مصطلحات موضوعية: chemistry.chemical_compound, Metabolomics, biology, chemistry, Metabolite, Metabolome, Computational biology, biology.organism_classification, Bacteria, Targeted metabolomics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::62d0ca01cb6a40fdc1d63aeb22831d8a
https://doi.org/10.1016/b978-0-08-099387-4.00005-3

المؤلفون: Roelco J. Kleijn, Joerg Martin Buescher, Stéphane Aymerich, Ludovic Le Chat, Uwe Sauer, Matthieu Jules

المساهمون: Institute of Molecular System Biology, Microbiologie et Génétique Moléculaire (MGM), Institut National de la Recherche Agronomique (INRA)-Institut National Agronomique Paris-Grignon (INA P-G)-Centre National de la Recherche Scientifique (CNRS), Sauer, Uwe

المصدر: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2010, 285 (3), pp.1587-1596. ⟨10.1074/jbc.M109.061747⟩
Journal of Biological Chemistry 3 (285), 1587-1596. (2010)

مصطلحات موضوعية: Transcription, Genetic, [SDV]Life Sciences [q-bio], Glyoxylate cycle, Malic enzyme, Catabolite repression, Intracellular Space, Malates, Bacillus subtilis, Biochemistry, Malate dehydrogenase, Substrate Specificity, 03 medical and health sciences, Metabolic flux analysis, Overflow metabolism, Molecular Biology, 030304 developmental biology, 0303 health sciences, Carbon Isotopes, biology, 030306 microbiology, Cell Biology, biology.organism_classification, Carbon, Citric acid cycle, Metabolism and Bioenergetics, Glucose, Genes, Bacterial, Isotope Labeling, Thermodynamics

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3312f92da04a56c2d1e594f68deab463
https://pubmed.ncbi.nlm.nih.gov/19917605