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1دورية أكاديميةDual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF
المؤلفون: Martin L. Decaris, Johanna R. Schaub, Chun Chen, Jacob Cha, Gail G. Lee, Megi Rexhepaj, Steve S. Ho, Vikram Rao, Megan M. Marlow, Prerna Kotak, Erine H. Budi, Lisa Hooi, Jianfeng Wu, Marina Fridlib, Shamra P. Martin, Shaoyi Huang, Ming Chen, Manuel Muñoz, Timothy F. Hom, Paul J. Wolters, Tushar J. Desai, Fernando Rock, Katerina Leftheris, David J. Morgans, Eve-Irene Lepist, Patrick Andre, Eric A. Lefebvre, Scott M. Turner
المصدر: Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)
مصطلحات موضوعية: Transforming growth factor-β, Precision-cut lung slice, Antifibrotic, αv integrin, PLN-74809, Diseases of the respiratory system, RC705-779
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1465-993X
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2دورية أكاديمية
المؤلفون: Johanna R. Schaub, Yann Malato, Coralie Gormond, Holger Willenbring
المصدر: Cell Reports, Vol 8, Iss 4, Pp 933-939 (2014)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource
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3Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF
المؤلفون: Patrick Andre, Martin Decaris, Chun Chen, Munoz Manuel, Hom Timothy, Scott M. Turner, Ming Chen, Tushar J. Desai, Megan M. Marlow, Cha Jacob, Eric Lefebvre, Steve S. Ho, Paul J. Wolters, Shaoyi Huang, Eve-Irene Lepist, Katerina Leftheris, David J Morgans, Lisa Hooi, Johanna R. Schaub, Vikram R. Rao, Jianfeng Wu, Marina Fridlib, Fernando Rock, Megi Rexhepaj, Erine H. Budi, Prerna Kotak, Gail Lee, Shamra Martin
المصدر: Respiratory research, vol 22, iss 1
Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)مصطلحات موضوعية: Precision-cut lung slice, Respiratory System, αv integrin, alpha(v) integrin, Cardiorespiratory Medicine and Haematology, Inbred C57BL, Mice, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, Receptors, Pulmonary fibrosis, Phosphorylation, alpha 1 Chain, Lung, biology, Transforming growth factor-β, Pirfenidone, Transforming growth factor-beta, medicine.anatomical_structure, 5.1 Pharmaceuticals, Respiratory, Nintedanib, Antifibrotic Agents, Development of treatments and therapeutic interventions, Cell activation, Type I collagen, Signal Transduction, medicine.drug, Integrin, Clinical Sciences, Collagen Type I, Cell Line, Diseases of the respiratory system, Bleomycin, Rare Diseases, medicine, Animals, Humans, Vitronectin, Smad3 Protein, PLN-74809, RC705-779, Integrin alpha6beta1, Animal, Epithelial Cells, Fibroblasts, medicine.disease, Coculture Techniques, Idiopathic Pulmonary Fibrosis, chemistry, Disease Models, Cancer research, biology.protein, Antifibrotic
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8943da51a8a3553a1e3711bc9a9ed07
https://escholarship.org/uc/item/5q12m0vq -
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المؤلفون: Johanna R. Schaub, Rik Derynck, Erine H. Budi, Martin Decaris, Scott M. Turner
المصدر: The Journal of pathologyReferences. 254(4)
مصطلحات موضوعية: 0301 basic medicine, Cell type, Population, Clinical settings, Pathology and Forensic Medicine, Extracellular matrix, 03 medical and health sciences, 0302 clinical medicine, Fibrosis, Transforming Growth Factor beta, medicine, Animals, Humans, education, Fibroblast, Pathological, education.field_of_study, business.industry, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, business, Transforming growth factor
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المؤلفون: Aras N. Mattis, Valerie M. Weaver, Lan Wei, Steve S. Ho, Yusuf A. Hannun, Lorena Pantano, Meghan S. Mooring, Bryan C. Fuchs, Jennifer Y. Chen, Alan C. Mullen, Regina Español-Suñer, Diego dos Santos Ferreira, Dean Yimlamai, Andrew M. Tager, Daniel Canals, Raymond T. Chung, Joe M. Segal, Vikram R. Rao, Amy Yu, Johanna R. Schaub, Mai Sedki, Caroline C. Duwaerts, Sarani Ghoshal, Hsiao-Yen Ma, Nadia M. E. Ayad, Scott M. Turner, Jimmy Kuang-Hsien Hu, Benjamin Newcomb, Megan M. Marlow, Stephanie A. Christenson, Izolda Mileva, Dean Sheppard, Sarah Alsamman
المصدر: Sci Transl Med
Science translational medicine, vol 12, iss 557مصطلحات موضوعية: 0301 basic medicine, Ceramide, Acid Ceramidase, Medical and Health Sciences, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Fibrosis, medicine, Hepatic Stellate Cells, 2.1 Biological and endogenous factors, Animals, Humans, Aetiology, Cancer, Adaptor Proteins, Signal Transducing, biology, Chemistry, Signal Transducing, Signal transducing adaptor protein, Adaptor Proteins, General Medicine, Biological Sciences, medicine.disease, Sphingolipid, Ubiquitin ligase, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Hepatic stellate cell, Hepatic fibrosis, Signal Transduction
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a4b8c3ed8a9921917b7e90c8313188
https://europepmc.org/articles/PMC7976849/ -
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المؤلفون: Eduard Gorina, Johanna R. Schaub, Chun Chen, Fernando Rock, Martin Decaris, Scott Turner, Eric Lefebvre, Eve Irene Lepist
المصدر: Idiopathic interstitial pneumonias.
مصطلحات موضوعية: Lung, biology, business.industry, Integrin, SMAD, respiratory system, Pharmacology, medicine.disease, Idiopathic pulmonary fibrosis, medicine.anatomical_structure, Fibrosis, In vivo, biology.protein, Medicine, Phosphorylation, business, IC50
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b8b517cd46c67bff686b0a8d62ec35c8
https://doi.org/10.1183/13993003.congress-2019.pa1298 -
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المؤلفون: Eric Lefebvre, Maureen Reilly, Chun Chen, Katerina Leftheris, Vikram R. Rao, Lisa Hooi, Jianfeng Wu, Eduard Gorina, Scott Turner, Gail Lee, Jake Cha, Tony Chen, Johanna R. Schaub, Martin Decaris, Prerna Kotak, Munoz Manuel, Patrick Andre, Hom Timothy, Shamra Martin, Megi Rexhepaj, Cooper Nicole
المصدر: Idiopathic interstitial pneumonias.
مصطلحات موضوعية: biology, Integrin Inhibition, business.industry, Integrin, Pirfenidone, respiratory system, Lung injury, medicine.disease, Bleomycin, respiratory tract diseases, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Fibrosis, biology.protein, Cancer research, Medicine, Nintedanib, business, Fibroblast, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::38c605362d65a6584058ceae0e0ba3df
https://doi.org/10.1183/13993003.congress-2019.pa1286 -
8دورية أكاديمية
المؤلفون: Johanna R. Schaub, Kari A. Huppert, Simone N. T. Kurial, Bernadette Y. Hsu, Ashley E. Cast, Bryan Donnelly, Rebekah A. Karns, Feng Chen, Milad Rezvani, Hubert Y. Luu, Aras N. Mattis, Anne-L
المصدر: Nature, Nature. 557(7704):247-251
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المؤلفون: Leigh Ann Burns-Naas, Chris Mathes, Carrie McMahon, Najah Abi-Gerges, Joseph C. Wu, Ray W. Chui, Paul Miller, Jonathan Davila, Carlos del Rio, Philip T. Sager, Johanna R. Schaub, Hugo M. Vargas, Andrea Ghetti, Dale Stevens
المصدر: Journal of pharmacological and toxicological methods. 98
مصطلحات موضوعية: Engineering, Societies, Pharmaceutical, Drug Industry, Drug-Related Side Effects and Adverse Reactions, education, Drug Evaluation, Preclinical, 030204 cardiovascular system & hematology, Toxicology, 030226 pharmacology & pharmacy, Risk Assessment, 03 medical and health sciences, 0302 clinical medicine, Animals, Humans, Inherited cardiomyopathy, West coast, Biotechnology industry, Pharmacology, business.industry, Safety pharmacology, Precision medicine, Variety (cybernetics), Safety risk, Engineering ethics, Translational science, business
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المؤلفون: Aras N. Mattis, Bryan Donnelly, Anne-Laure Rougemont, Johanna R. Schaub, Feng Chen, Milad Rezvani, Stacey S. Huppert, Ashley Cast, Hubert Y. Luu, Kari A. Huppert, Simone N. T. Kurial, Philip J. Rosenthal, Holger Willenbring, Bernadette Y. Hsu, Rebekah Karns
المصدر: Nature, vol 557, iss 7704
Nature
Nature, Vol. 557, No 7704 (2018) pp. 247-251مصطلحات موضوعية: 0301 basic medicine, Male, ddc:616.07, Inbred C57BL, Regenerative Medicine, Oral and gastrointestinal, Mice, 0302 clinical medicine, Transforming Growth Factor beta, Metaplasia, Alagille syndrome, Receptors, 2.1 Biological and endogenous factors, Aetiology, Biliary Tract, Liver injury, Cholestasis, Multidisciplinary, Receptors, Notch, Bile duct, Liver Disease, Transdifferentiation, Cell biology, Alagille Syndrome, medicine.anatomical_structure, Hepatocyte, Cell Transdifferentiation, 030211 gastroenterology & hepatology, Female, Stem Cell Research - Nonembryonic - Non-Human, medicine.symptom, Signal Transduction, Notch, General Science & Technology, 1.1 Normal biological development and functioning, Chronic Liver Disease and Cirrhosis, Notch signaling pathway, Biology, Article, 03 medical and health sciences, Underpinning research, medicine, Animals, Humans, Cell Proliferation, Epithelial Cells, medicine.disease, Stem Cell Research, Mice, Inbred C57BL, 030104 developmental biology, Hepatocytes, Bile Ducts, Digestive Diseases
وصف الملف: application/pdf