-
1دورية أكاديمية
المؤلفون: Carlos García-Echeverría, Patricia Imbach, Johannes Roesel, Peter Fuerst, Marc Lang, Vito Guagnano, Maria Noorani, Johann Zimmermann, Pascal Furet
المصدر: CHIMIA, Vol 57, Iss 4 (2003)
مصطلحات موضوعية: Antitumor agents, Drug design, Enzyme inhibitors, Peptidomimetic, Chemistry, QD1-999
وصف الملف: electronic resource
Relation: https://chimia.ch/chimia/article/view/3683; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424
-
2
المؤلفون: Johannes Roesel, Giorgio Caravatti, Trixie Wagner, Pascal Furet, Markus Wartmann, Paul W. Manley, Phi Tran
المصدر: Biochemistry. 57:5576-5590
مصطلحات موضوعية: 0301 basic medicine, BALB 3T3 Cells, medicine.drug_class, Newly diagnosed, Biochemistry, Gene Expression Regulation, Enzymologic, Mice, 03 medical and health sciences, chemistry.chemical_compound, hemic and lymphatic diseases, medicine, Animals, Humans, Midostaurin, Systemic mastocytosis, Protein Kinase Inhibitors, Cells, Cultured, Cell Proliferation, Kinase, business.industry, Gene Expression Profiling, Myeloid leukemia, Fibroblasts, Protein kinase inhibitor, Staurosporine, medicine.disease, Leukemia, Myeloid, Acute, Leukemia, 030104 developmental biology, fms-Like Tyrosine Kinase 3, chemistry, Mutation, Cancer research, business
-
3
المؤلفون: Georg E. Winter, Catherine Dutreix, Johannes Roesel, Keiryn L. Bennett, Juliana Schwaab, Giulio Superti-Furga, Manuela Gridling, Katharina Blatt, Barbara Peter, Gabriele Stefanzl, Emir Hadzijusufovic, Gregor Hoermann, Gregor Eisenwort, Deepti Radia, Andreas Reiter, Uwe Rix, Paul W. Manley, Peter Valent
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, Histamine secretion, Cell Survival, Metabolite, Syk, Biology, Histamine Release, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, medicine, Staurosporine, Humans, Midostaurin, Mast Cells, Systemic mastocytosis, Protein Kinase Inhibitors, Aged, Hematology, Middle Aged, Mast cell, medicine.disease, Basophils, Proto-Oncogene Proteins c-kit, 030104 developmental biology, medicine.anatomical_structure, Oncology, chemistry, 030220 oncology & carcinogenesis, Immunology, Cancer research, Female, Histamine, Mastocytosis, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716d800cd4056e59247c8434ef77be2c
https://europepmc.org/articles/PMC4896384/ -
4
المؤلفون: Jingrui Jiang, Erik Nelson, Johannes Roesel, Daisy Moreno, Edward A. Fox, Richard Stone, Arghya Ray, Rosemary Barrett, Elizabeth Hall-Meyers, Pascal Furet, Ilene Galinsky, Guido Bold, Gary Gilliland, Andrew L. Kung, James D. Griffin, Ellen Weisberg, Jan Cools, John F. Daley, Suzan Lazo-Kallanian, Renee D. Wright
المصدر: Blood. 112:5161-5170
مصطلحات موضوعية: Immunology, Mutant, Antineoplastic Agents, Drug resistance, Biology, Biochemistry, Cell Line, Mice, fluids and secretions, In vivo, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Protein kinase A, Protein Kinase Inhibitors, Protein Kinase C, Neoplasia, hemic and immune systems, Cell Biology, Hematology, Staurosporine, medicine.disease, Leukemia, Myeloid, Acute, Leukemia, fms-Like Tyrosine Kinase 3, Drug Resistance, Neoplasm, Cell culture, embryonic structures, Fms-Like Tyrosine Kinase 3, Cancer research, Mutant Proteins, FLT3 Inhibitor, Carbanilides
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf5c78b6723a3dffe886bb633d95b5e
https://doi.org/10.1182/blood-2008-02-138065 -
5
المؤلفون: Guido Bold, Johannes Roesel, Pascal Furet, Vito Guagnano, Thomas Meyer
المصدر: Journal of Medicinal Chemistry. 49:4451-4454
مصطلحات موضوعية: Models, Molecular, Phenylalanine, Antineoplastic Agents, chemistry.chemical_compound, Adenosine Triphosphate, Cell Line, Tumor, hemic and lymphatic diseases, Drug Discovery, Humans, Cysteine, chemistry.chemical_classification, Binding Sites, Kinase, Myeloid leukemia, Protein Structure, Tertiary, Thiazoles, Enzyme, fms-Like Tyrosine Kinase 3, chemistry, Biochemistry, Leukemia, Myeloid, Acute Disease, Mutation, Fms-Like Tyrosine Kinase 3, Molecular Medicine, Signal transduction, Adenosine triphosphate
-
6
المؤلفون: Peter Marynen, Nicole Mentens, Hilde Vranckx, Johannes Roesel, Herlinde Dumez, Hans Prenen, Allan T. van Oosterom, Anne Hagemeijer, Bartosz Wasag, Michel Stul, Maria Debiec-Rychter, Jan Cools, Raf Sciot
المصدر: Gastroenterology
مصطلحات موضوعية: Adult, Male, Pathology, medicine.medical_specialty, Receptor, Platelet-Derived Growth Factor alpha, Gastrointestinal Stromal Tumors, Antineoplastic Agents, Drug resistance, PDGFRA, Biology, medicine.disease_cause, Piperazines, medicine, Humans, Aged, Mutation, Hepatology, Gastroenterology, Imatinib, Exons, Middle Aged, Staurosporine, digestive system diseases, Proto-Oncogene Proteins c-kit, Pyrimidines, Imatinib mesylate, Drug Resistance, Neoplasm, Benzamides, Cancer cell, Imatinib Mesylate, Cancer research, Female, Human medicine, Tyrosine kinase, medicine.drug
-
7
المؤلفون: Johannes Roesel, Kurt Laumen, Marc Lang, Carlos Garcia-Echeverria, Patricia Imbach, Maria Noorani, Pascal Furet, Vito Guagnano, Peter Fuerst, Juergen Koeppler, Johann Zimmermann
المصدر: Journal of Medicinal Chemistry. 47:4810-4813
مصطلحات موضوعية: Models, Molecular, Proteasome Endopeptidase Complex, Proteasome Inhibition, Antineoplastic Agents, Cysteine Proteinase Inhibitors, Inhibitory Concentration 50, Structure-Activity Relationship, Multienzyme Complexes, Drug Discovery, Tumor Cells, Cultured, Humans, High activity, chemistry.chemical_classification, Binding Sites, Molecular Structure, biology, Hydrogen Bonding, In vitro, Cysteine Endopeptidases, Enzyme, chemistry, Biochemistry, Proteasome, Cell culture, Enzyme inhibitor, biology.protein, Molecular Medicine, Structure based, Drug Screening Assays, Antitumor, Oligopeptides, Cell Division
-
8
المؤلفون: Heinrich Peter, Barbara E. Roggo, Matthew SiLLS, Frank Petersen, Johannes Roesel, Theophile Moerker
المصدر: The Journal of Antibiotics. 49:13-19
مصطلحات موضوعية: Pharmacology, medicine.hormone, Protease, Lactams, Endothelins, medicine.medical_treatment, Ligand binding assay, Stachybotrys, Biological activity, HIV Protease Inhibitors, Biology, biology.organism_classification, Rats, HIV-1 protease, Biochemistry, Enzyme inhibitor, Fermentation, Drug Discovery, medicine, biology.protein, Animals, HIV Protease Inhibitor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ecd0847cef919dd2839fdf988ef957
https://doi.org/10.7164/antibiotics.49.13 -
9
المؤلفون: Robert Gurny, Frank Kubel, Johannes Roesel, Jean-Christophe Leroux, Bruno Galli, Robert Cozens, Eric Doelker
المصدر: Journal of Pharmaceutical Sciences. 84:1387-1391
مصطلحات موضوعية: Polymers, Polyesters, medicine.medical_treatment, Acrylic Resins, Administration, Oral, Biological Availability, Pharmaceutical Science, Pharmacology, Dosage form, Mice, chemistry.chemical_compound, Drug Delivery Systems, Polymethacrylic Acids, Pharmacokinetics, Oral administration, medicine, Animals, Lactic Acid, Volume of distribution, Drug Carriers, Mice, Inbred BALB C, Protease, biology, HIV Protease Inhibitors, Enteric coating, Methacrylic acid, chemistry, Biochemistry, Enzyme inhibitor, Delayed-Action Preparations, Injections, Intravenous, Lactates, biology.protein, Carbamates, Oligopeptides, Half-Life, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad6a849a1dd9e0b9939a86b57935281
https://doi.org/10.1002/jps.2600841202 -
10
المؤلفون: Barbara E. Roggo, Johannes Roesel, Frank Petersen, Hans-Beat Jenny, Heinrich Peter, Ron Delmendo
المصدر: The Journal of Antibiotics. 47:136-142
مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Protease, Natural product, biology, medicine.medical_treatment, Biological activity, HIV Protease Inhibitors, Anti-Bacterial Agents, chemistry.chemical_compound, Enzyme, chemistry, HIV-1 protease, Biochemistry, Actinomycetaceae, Fermentation, Drug Discovery, biology.protein, medicine, Hydroxymethyl, Benzopyrenes, Furans, Tetronic acid
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afc04da64c8b61e9841740ec61d6ceb
https://doi.org/10.7164/antibiotics.47.136