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1دورية أكاديمية
المؤلفون: Johannes Schiebel, Roberto Gaspari, Tobias Wulsdorf, Khang Ngo, Christian Sohn, Tobias E. Schrader, Andrea Cavalli, Andreas Ostermann, Andreas Heine, Gerhard Klebe
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2
المؤلفون: Thien Anh Le, Sneha Basak, Bernd Engels, Johannes Schiebel, Josef Kehrein, Jonas D. Weinrich, Benjamin Merget, Peter J. Tonge, Caroline Kisker, Christoph A. Sotriffer, S. Eltschkner, Shabnam Davoodi
المصدر: ACS Infect Dis
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Staphylococcus aureus, INHA, Stereochemistry, 030106 microbiology, Substituent, Substrate (chemistry), Context (language use), Mycobacterium tuberculosis, Reductase, Tautomer, Article, Isoenzymes, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Infectious Diseases, Enzyme, Structural biology, chemistry, Isomerism, Enzyme Inhibitors, Oxidoreductases
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3
المؤلفون: Johannes Schiebel, Caroline Kisker, Lauren A. Spagnuolo, Christoph A. Sotriffer, Andrew Chang, Benjamin Merget, Michael V. Baxter, Gopal R. Bommineni, Mona Tareilus, Peter J. Tonge, Weixuan Yu
المصدر: Biochemistry. 54:1943-1955
مصطلحات موضوعية: Models, Molecular, chemistry.chemical_classification, Staphylococcus aureus, biology, Water, Active site, Drug design, Substrate (chemistry), Biological activity, Enoyl-(Acyl-Carrier-Protein) Reductase (NADH), Biochemistry, Catalysis, Article, Structure-Activity Relationship, Enzyme, Bacterial Proteins, Drug development, chemistry, Oxidoreductase, Catalytic Domain, biology.protein, Structure–activity relationship
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4
المصدر: Journal of the American Chemical Society. 139(30)
مصطلحات موضوعية: Models, Molecular, Binding Sites, Thermolysin, Humans, Thermodynamics, Calorimetry, Crystallography, X-Ray, Ligands, Hydrophobic and Hydrophilic Interactions
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5
المؤلفون: Maria Hirschbeck, Christoph A. Sotriffer, Gopal R. Bommineni, Peter J. Tonge, S. Shah, Jason E. Cummings, Sandra Eltschkner, Andrew Chang, Susan E. Knudson, Weixuan Yu, Pan Pan, Yang Lu, Mona Tareilus, Richard A. Slayden, Johannes Schiebel, Li Liu, Caroline Kisker, Stephen G. Walker
المصدر: Journal of Biological Chemistry. 289:15987-16005
مصطلحات موضوعية: Staphylococcus aureus, Pyridones, Stereochemistry, Microbial Sensitivity Tests, Reductase, Crystallography, X-Ray, medicine.disease_cause, Polymerase Chain Reaction, Biochemistry, Mice, medicine, Animals, Enzyme Inhibitors, Molecular Biology, DNA Primers, Mice, Inbred ICR, Base Sequence, Molecular Structure, biology, Drug discovery, Rational design, Cell Biology, Enoyl-(Acyl-Carrier-Protein) Reductase (NADH), Enzyme structure, Anti-Bacterial Agents, Acyl carrier protein, Enzyme inhibitor, Drug Design, Enzymology, biology.protein, Female, Antibacterial activity
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c8bfde90ae1c1d56a2e538f8c95c81
https://doi.org/10.1074/jbc.m113.532804 -
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المؤلفون: Gopal R. Bommineni, Andrew Chang, Weixuan Yu, Pan Pan, Avinash Khanna, Caroline Kisker, Michael V. Baxter, Peter J. Tonge, Johannes Schiebel, Christoph A. Sotriffer
المصدر: Biochemistry. 52:4217-4228
مصطلحات موضوعية: chemistry.chemical_compound, Protein structure, chemistry, Stereochemistry, Drug discovery, In vivo, Diphenyl ether, Rational design, Plasma protein binding, Reductase, Biochemistry, Affinities
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7
المؤلفون: Yang Lu, Caroline Kisker, Johannes Schiebel, Kanishk Kapilashrami, Zhuo Zhang, Stewart L. Fisher, Peter J. Tonge, Fereidoon Daryaee, Christoph A. Sotriffer, Stephen G. Walker, Andrew Chang
مصطلحات موضوعية: 0301 basic medicine, Pseudomonas aeruginosa, Kinetics, General Chemistry, Pharmacology, Reductase, Biology, medicine.disease_cause, Article, 03 medical and health sciences, 030104 developmental biology, Biochemistry, In vivo, Staphylococcus aureus, Pharmacodynamics, ddc:570, ddc:540, medicine, Antibacterial activity, Function (biology)
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aabe47eab91483b8602c3e3f84d2bc5
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-191218 -
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المؤلفون: Peter J. Tonge, Hao Lu, Andrew Chang, Michael V. Baxter, Johannes Schiebel, Caroline Kisker
المصدر: Structure. 20:802-813
مصطلحات موضوعية: Staphylococcus aureus, Protein Conformation, Molecular Sequence Data, Reductase, Biology, Ligands, medicine.disease_cause, Article, Substrate Specificity, Structure-Activity Relationship, 03 medical and health sciences, Protein structure, Bacterial Proteins, Structural Biology, In vivo, medicine, Structure–activity relationship, Amino Acid Sequence, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, 030306 microbiology, Fatty Acids, Fatty acid, Ligand (biochemistry), Enoyl-(Acyl-Carrier-Protein) Reductase (NADH), 3. Good health, Kinetics, Enzyme, chemistry, Biochemistry
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9
المصدر: Pharmazie in unserer Zeit. 41:64-70
مصطلحات موضوعية: Pharmacology, Pharmaceutical Science, Pharmacology (medical)
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10
المؤلفون: C.M. Schaefer, Johannes Schiebel, Gopal R. Bommineni, Caroline Kisker, Kanishk Kapilashrami, Peter J. Tonge, Agnes Fekete, Martin J. Mueller
المصدر: The Journal of biological chemistry. 288(47)
مصطلحات موضوعية: Fatty Acid Synthases, Stereochemistry, Phospholipid, Antitubercular Agents, Biochemistry, Protein Structure, Secondary, Mycolic acid, Mycobacterium tuberculosis, chemistry.chemical_compound, Drug Delivery Systems, Transferase, Tuberculosis, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, biology, Substrate (chemistry), Cell Biology, biology.organism_classification, Enzyme structure, Protein Structure, Tertiary, Enzyme, chemistry, Mycolic Acids, Protein Structure and Folding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311110dd543ca970ec343077552b68a6
https://pubmed.ncbi.nlm.nih.gov/24108128