نتائج البحث - "John C. Dittmar"

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دورية أكاديمية

Early-onset torsion dystonia: a novel high-throughput yeast genetic screen for factors modifying protein levels of torsinAΔE

المؤلفون: Lucía F. Zacchi, John C. Dittmar, Michael J. Mihalevic, Annette M. Shewan, Benjamin L. Schulz, Jeffrey L. Brodsky, Kara A. Bernstein

المصدر: Disease Models & Mechanisms, Vol 10, Iss 9, Pp 1129-1140 (2017)

مصطلحات موضوعية: Yeast, Genetic screen, Protein levels, Protein disulfide isomerase, TorsinA, Dystonia, Medicine, Pathology, RB1-214

وصف الملف: electronic resource

Relation: http://dmm.biologists.org/content/10/9/1129; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

URL الوصول: https://doaj.org/article/f7ac7a235cf04b5ba2e8af83825ca350

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A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers

المؤلفون: Lodewyk F. A. Wessels, René Bernards, Robert J.D. Reid, John C. Dittmar, Evert Bosdriesz, Cor Lieftink, Roderick L. Beijersbergen, Sake van Wageningen, Rodney Rothstein, Tonći Šuštić

المساهمون: Bioinformatics

المصدر: Genome Medicine
Šuštić, T, van Wageningen, S, Bosdriesz, E, Reid, R J D, Dittmar, J, Lieftink, C, Beijersbergen, R L, Wessels, L F A, Rothstein, R & Bernards, R 2018, ' A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers ', Genome Medicine, vol. 10, no. 1, 90, pp. 90 . https://doi.org/10.1186/s13073-018-0600-z
Genome Medicine, 10(1):90. BioMed Central
Genome Medicine, Vol 10, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: 0301 basic medicine, Yeasts/genetics, Proto-Oncogene Proteins c-jun, Mutant, lcsh:Medicine, medicine.disease_cause, Colonic Neoplasms/drug therapy, Yeasts, Genetics (clinical), Tumor, Benzimidazoles/pharmacology, Pyrimidinones/pharmacology, Kinase, MEK inhibitor, MAP Kinase Kinase Kinases, Endoplasmic Reticulum Stress, 3. Good health, Colon cancer, Colonic Neoplasms, Molecular Medicine, KRAS, Signal transduction, Antineoplastic Agents/pharmacology, lcsh:QH426-470, Pyridones, Protein-Serine-Threonine Kinases/genetics, Antineoplastic Agents, Pyrimidinones, Ire1, Biology, Protein Serine-Threonine Kinases, Cell Line, Proto-Oncogene Proteins p21(ras), Proto-Oncogene Proteins p21(ras)/genetics, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Cell Line, Tumor, Endoribonucleases, Endoribonucleases/genetics, Genetics, medicine, Humans, Molecular Biology, Protein Kinase Inhibitors, JUN, Pyridones/pharmacology, Research, lcsh:R, Correction, ERN1, Proto-Oncogene Proteins c-jun/genetics, lcsh:Genetics, MAP Kinase Kinase Kinases/antagonists & inhibitors, 030104 developmental biology, HEK293 Cells, Protein Kinase Inhibitors/pharmacology, Cancer cell, Cancer research, Unfolded protein response, Unfolded Protein Response, Benzimidazoles, JNK, Genetic screen