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المؤلفون: Xiang S. Ye, Kerry L. Blanchard, Li Fan, Shaoyou Chu, Jian Du, Guoxin Zhu, John E. Toth, Robert D. Van Horn, Mary M. Mader, Tinggui Yin, Richard P. Beckmann
المصدر: Journal of Biological Chemistry. 285:21849-21857
مصطلحات موضوعية: G2 Phase, Threonine, Umbilical Veins, Aurora inhibitor, Aurora B kinase, Mitosis, Cell Cycle Proteins, Polo-like kinase, Protein Serine-Threonine Kinases, Biology, Biochemistry, Histones, Mice, Aurora Kinases, Proto-Oncogene Proteins, CDC2 Protein Kinase, Animals, Aurora Kinase B, Humans, Phosphorylation, Molecular Biology, Aurora Kinase A, Cell Cycle, Cell Biology, Cell biology, enzymes and coenzymes (carbohydrates), Mitotic exit, biological phenomena, cell phenomena, and immunity, Cell Division, Cytokinesis, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fde1fe786dca815541437f1d8521e1
https://doi.org/10.1074/jbc.m110.141010 -
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المؤلفون: John E. Toth, Matthew Ernst Voss, Robert D. Boyer, Hong-Yu Li, Sreenivasa R. Mundla, Yan Wang, Arindam Chatterjee, J. Scott Sawyer, William Thomas Mcmillen
المصدر: Tetrahedron. 63:11763-11770
مصطلحات موضوعية: Analog synthesis, Methanesulfonyl chloride, Organic Chemistry, Biochemistry, chemistry.chemical_compound, chemistry, Microwave heating, Amide, Yield (chemistry), Intramolecular force, Drug Discovery, Organic chemistry, Quinazolinone, Boronic acid
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المؤلفون: Mary M. Mader, Michael E. Christe, Xushan Wang, Laura J. Bloem, Jeffrey K. Smallwood, Najia Jin, Theodore Goodson, Arindam Chatterjee, Xiaohong Yu, William F. Matter, John E. Toth, Robert M. Campbell, Chris J. Vlahos
المصدر: Journal of Biological Chemistry. 280:19298-19305
مصطلحات موضوعية: Time Factors, MAP Kinase Kinase 4, Muscle Proteins, Apoptosis, Mitogen-activated protein kinase kinase, p38 Mitogen-Activated Protein Kinases, Biochemistry, MAP2K7, Mice, chemistry.chemical_compound, Transgenes, Enzyme Inhibitors, RNA, Small Interfering, Anisomycin, Glutathione Transferase, Kinase, MAP Kinase Kinase Kinases, COS Cells, Quinolines, Cytokines, Electrophoresis, Polyacrylamide Gel, Plasmids, Signal Transduction, Ultraviolet Rays, p38 mitogen-activated protein kinases, Blotting, Western, DNA Fragmentation, Protein Serine-Threonine Kinases, Biology, Transfection, Catalysis, Inhibitory Concentration 50, Animals, Humans, Protein kinase A, Molecular Biology, Nucleic Acid Synthesis Inhibitors, Mitogen-Activated Protein Kinase Kinases, Dose-Response Relationship, Drug, MAP kinase kinase kinase, Tumor Necrosis Factor-alpha, Myocardium, JNK Mitogen-Activated Protein Kinases, Cell Biology, Molecular biology, Enzyme Activation, Models, Chemical, chemistry, Pyrazoles, Cyclin-dependent kinase 9, Interleukin-1
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae4d48cfa570ea18d99988735d7823c
https://doi.org/10.1074/jbc.m413059200 -
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المؤلفون: Richard M. Schultz, William J. Ehlhardt, John F. Worzalla, Jesse R. Bewley, John E. Toth, Kim K. Klingerman, James Edward Ray, George B. Boder, Gerald B. Grindey, Sharon M. Rinzel, Susan B. Gates, Leonard C. Weir
المصدر: Journal of Medicinal Chemistry. 40:1018-1025
مصطلحات موضوعية: Pharmacokinetics, Biochemistry, Chemistry, Oral administration, In vivo, Ratón, Drug Discovery, Molecular Medicine, Metabolism, Pharmacology, Chemical synthesis, In vitro, Oncolytic virus
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المؤلفون: Jack B. Deeter, James Edward Ray, John E. Toth
المصدر: The Journal of Organic Chemistry. 58:3469-3472
مصطلحات موضوعية: Chemistry, Organic Chemistry, Resolution (electron density), Condensation reaction, Combinatorial chemistry, Amination
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::725ab8b66d84e5f49b16fc6fca06cfe6
https://doi.org/10.1021/jo00064a044 -
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المؤلفون: James Edward Ray, John E. Toth, Jack B. Deeter
المصدر: ChemInform. 24
مصطلحات موضوعية: Chemistry, Resolution (electron density), General Medicine, Combinatorial chemistry
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المؤلفون: John E. Toth, Lawrence C. Creemer, Herbert A. Kirst
المصدر: ChemInform. 33
مصطلحات موضوعية: chemistry.chemical_classification, Hydrogen bond, Chemistry, medicine.drug_class, Stereochemistry, Antibiotics, General Medicine, Tylosin, Antimicrobial, Tautomer, Enol, In vitro, chemistry.chemical_compound, medicine, Lactone
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المؤلفون: William J. Ehlhardt, Jesse R. Bewley, John F. Worzalla, Joseph M. Woodland, J. Jeffry Howbert, John E. Toth, Glen C. Todd, Gerald B. Grindey
المصدر: Chemical Research in Toxicology. 5:667-673
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, medicine.drug_class, Metabolite, Antineoplastic Agents, Toxicology, Methemoglobinemia, Mass Spectrometry, Methemoglobin, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Oral administration, medicine, Animals, Mice, Inbred C3H, Aniline Compounds, General Medicine, Metabolism, medicine.disease, Sulfonylurea, Sulfonylurea Compounds, chemistry, Biochemistry, Toxicity, Urea, Female
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e6b4820a14d0bbfa98749511e5099f
https://doi.org/10.1021/tx00029a012 -
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المؤلفون: John E. Toth, Arindam Chatterjee, William Thomas Mcmillen, Hong-Yu Li, J. Scott Sawyer, Sreenivasa R. Mundla, Matthew Ernst Voss, Yan Wang, Robert D. Boyer
المصدر: ChemInform. 39
مصطلحات موضوعية: chemistry.chemical_compound, Analog synthesis, Methanesulfonyl chloride, chemistry, Microwave heating, Amide, Intramolecular force, Yield (chemistry), General Medicine, Combinatorial chemistry, Quinazolinone, Boronic acid
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المؤلفون: Sehila Pleite, Mario Barberis, Robert Dean Dally, Eugenio de Diego, White Wesley Todd, Miriam del Prado, Concepcion Sanchez-Martinez, Timothy Alan Shepherd, Bryan D. Anderson, Luisa M. Martín Cabrejas, Chuan Shih, Jeffrey A. Wolos, Li C. Li, Carmen Dominguez, Alfonso De Dios, Beatriz López de Uralde, C. Richard Nevill, Enrique Jambrina, Arindam Chatterjee, Carlos Montero, Richard C. Schultz, Leticia Perez, Paul Lee, Carlos Jaramillo, Tiechao Li, María José Lorite, † Jaime Blanco-Urgoiti, John E. Toth, Robert M. Campbell, Rosanne Bonjouklian, Mary M. Mader
المصدر: Bioorganicmedicinal chemistry letters. 18(1)
مصطلحات موضوعية: Imidazopyridine, Stereochemistry, Pyridines, Clinical Biochemistry, Anti-Inflammatory Agents, Pharmaceutical Science, Biochemistry, Chemical synthesis, Mitogen-Activated Protein Kinase 14, Mice, Structure-Activity Relationship, Adenosine Triphosphate, In vivo, Drug Discovery, Structure–activity relationship, Potency, Animals, Edema, Humans, Molecular Biology, Mice, Inbred BALB C, biology, Chemistry, Tumor Necrosis Factor-alpha, Organic Chemistry, Imidazoles, In vitro, Peptide Fragments, Rats, ErbB Receptors, Enzyme inhibitor, Mitogen-activated protein kinase, biology.protein, Molecular Medicine, Benzimidazoles
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