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المؤلفون: Leopoldo Luistro, Packman Kathryn E, James Cai, Daisy Carvajal, Thomas D. Nevins, Michael J. Bennett, David C. Heimbrook, Gaurav Tyagi, Wei He, Xin Wei, John Frederick Boylan, Melissa Smith, Tai-An Lin
المصدر: Molecular Therapy. 22(2):359-370
مصطلحات موضوعية: Anions, Polymers, Gene Expression, Biology, Transfection, Caveolins, Mice, In vivo, Cations, Cell Line, Tumor, Gene expression, Drug Discovery, medicine, Genetics, Animals, Humans, RNA, Small Interfering, Molecular Biology, Pharmacology, Gene knockdown, Leukemia, Gene Transfer Techniques, RNA, medicine.disease, Lipids, Cell biology, Disease Models, Animal, medicine.anatomical_structure, Cell culture, Nanoparticles, Molecular Medicine, Original Article, Bone marrow
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المؤلفون: Eunice L. Kwak, Jonathan Deutsch, Jennifer J. Wheler, Stanislaw M. Mikulski, Anthony W. Tolcher, Astrid Koehler, Amita Patnaik, Zhi Xin Xu, Geoffrey I. Shapiro, Kyriakos P. Papadopoulos, Razelle Kurzrock, Wells A. Messersmith, John Frederick Boylan, Mark DeMario, Gerald S. Falchook, Darlene Gibbon, Ka Wang, Steven A. Middleton, James Song, Arvind Dasari
المصدر: Journal of Clinical Oncology. 30:2348-2353
مصطلحات موضوعية: Fluorodeoxyglucose, Cancer Research, medicine.medical_specialty, business.industry, ORIGINAL REPORTS, Pharmacology, medicine.disease, Gastroenterology, Rash, Oncology, Pharmacokinetics, Pharmacodynamics, Internal medicine, medicine, Chills, Dosing, medicine.symptom, business, Hypophosphatemia, Gamma secretase, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07c2a3c8d62a4e448b510cec1264b9f
https://doi.org/10.1200/jco.2011.36.8282 -
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المؤلفون: Jing Hu, Ann F. Hoffman, Xiaobing Deng, Karen Zipf, Maria Vilenchik, Ann Polonskaia, Daina Z. Ewton, Eileen Friedman, John Frederick Boylan, Kin-Chun Luk
المصدر: Molecular Cancer Therapeutics. 10:2104-2114
مصطلحات موضوعية: DYRK1B, Cancer Research, Cell, Antineoplastic Agents, Apoptosis, Caspase 3, Protein Serine-Threonine Kinases, Biology, Deoxycytidine, Resting Phase, Cell Cycle, Article, Cell Line, Tumor, medicine, Humans, Protein Kinase Inhibitors, Cellular Senescence, Kinase, Cell Cycle, Drug Synergism, Exons, Protein-Tyrosine Kinases, Cell cycle, Gemcitabine, Cell biology, Pancreatic Neoplasms, medicine.anatomical_structure, Oncology, Cell culture, Cancer cell, Cancer research, Cisplatin, Cell aging, DNA Damage
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c965b4e89680a7f204ddda7f37e26a5f
https://doi.org/10.1158/1535-7163.mct-11-0498 -
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المؤلفون: Nam T. Le, Kang Le, Zhi Chen, Yingsi Chen, Tom Nevins, Shaoqing Chen, Steve Mischke, David Joseph Bartkovitz, Jianping Cai, Goli Naderi-Oboodi, Weiguo Qing, Xin-Jie Chu, John Frederick Boylan, Kin Chun Luk, Yi Chen, Peter Michael Wovkulich
المصدر: Bioorganicmedicinal chemistry letters. 22(2)
مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Cell Cycle Proteins, Polo-like kinase, Protein Serine-Threonine Kinases, Biochemistry, PLK1, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Cell Line, Tumor, Proto-Oncogene Proteins, Drug Discovery, Potency, Structure–activity relationship, Animals, Humans, Molecular Biology, Protein Kinase Inhibitors, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, Kinase, Chemistry, Organic Chemistry, Stereoisomerism, Azepines, Neoplasms, Experimental, In vitro, Pyrimidines, Cell culture, Molecular Medicine, Lead compound
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المؤلفون: Anna C. Pavlick, John Frederick Boylan, Iman Osman, Farbod Darvishian, Laura Poliseno, Adele Haimovic, Silvia Menendez, Miguel F. Segura, Chanh Huynh, Ratna Medicherla, Eva Hernando, Shulian Shang, Yongzhao Shao
المصدر: PLoS ONE, Vol 6, Iss 11 (2011)
PLoS ONEمصطلحات موضوعية: Oncology, medicine.medical_specialty, Science, Section (typography), lcsh:Medicine, Gamma-Secretase Inhibitor RO4929097, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, lcsh:Science, 030304 developmental biology, 0303 health sciences, Multidisciplinary, business.industry, Melanoma, lcsh:R, Correction, medicine.disease, 3. Good health, 030220 oncology & carcinogenesis, Medicine, lcsh:Q, business
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المؤلفون: Melissa Smith, Wei He, Brian Higgins, Xuefeng Yin, Leopoldo Luistro, Packman Kathryn E, John Frederick Boylan, David C. Heimbrook, Daisy Carvajal, James Cai, Christine Rizzo, Tom Nevins, Kenneth Kolinsky
المصدر: Molecular oncology. 5(3)
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Angiogenesis, Angiogenesis Inhibitors, Antineoplastic Agents, Drug resistance, Pharmacology, Tissue culture, Mice, Text mining, In vivo, Internal medicine, Cell Line, Tumor, Neoplasms, Genetics, medicine, Animals, Humans, Interleukin 8, Dosing, business.industry, Interleukin-6, Interleukin-8, General Medicine, Benzazepines, Xenograft Model Antitumor Assays, Treatment Outcome, Cell culture, Drug Resistance, Neoplasm, Papers, Molecular Medicine, Amyloid Precursor Protein Secretases, business
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المؤلفون: John Frederick Boylan, Huifeng Niu, Christine Tardell, Brenden Chen, Packman Kathryn E, Brian Higgins
المصدر: Molecular Cancer Therapeutics. 10:B130-B130
مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Gene knockdown, Melanoma, Wild type, Biology, medicine.disease, In vitro, Cell biology, Oncology, medicine, Kinase activity, Protein kinase B, PI3K/AKT/mTOR pathway
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a7c13d2df9dfe9fdea0c519df4d67fc0
https://doi.org/10.1158/1535-7163.targ-11-b130 -
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المؤلفون: John Frederick Boylan, Iman Osman, Laura Poliseno, Chanh Huynh, Silvia Menendez, Anna C. Pavlick, Shulian Shang, Ratna Medicherla, Miguel F. Segura, Eva Hernando, Yongzhao Shao, Adele Haimovic, Farbod Darvishian
المصدر: PLoS ONE
PLoS ONE, Vol 6, Iss 9, p e25264 (2011)مصطلحات موضوعية: Melanomas, Pathology, Skin Neoplasms, lcsh:Medicine, Biochemistry, Mice, 0302 clinical medicine, Drug Discovery, Molecular Cell Biology, HES1, lcsh:Science, Melanoma, Skin Tumors, 0303 health sciences, Multidisciplinary, Receptors, Notch, biology, Malignant Melanoma, Immunohistochemistry, 3. Good health, Oncology, 030220 oncology & carcinogenesis, Medicine, Stem cell, Research Article, Biotechnology, Signal Transduction, Drugs and Devices, medicine.medical_specialty, Drug Research and Development, Notch signaling pathway, Malignant Skin Neoplasms, Dermatology, Real-Time Polymerase Chain Reaction, Gamma-Secretase Inhibitor RO4929097, 03 medical and health sciences, Cell Line, Tumor, medicine, Animals, Humans, Biology, Gamma secretase, Cell Proliferation, 030304 developmental biology, Cell growth, lcsh:R, Cancers and Neoplasms, Benzazepines, Molecular Development, medicine.disease, Xenograft Model Antitumor Assays, Signaling, biology.protein, Cancer research, lcsh:Q, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase, Developmental Biology
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المؤلفون: Wen-hui Li, Sherif Daouti, Christine Rizzo, Neal Rosen, Brian Higgins, Huisheng Wang, John Frederick Boylan, Yang Wen, Packman Kathryn E, Huifeng Niu, David C. Heimbrook
المصدر: Cancer Research. 71:5036-5036
مصطلحات موضوعية: MAPK/ERK pathway, Genetics, Cancer Research, Mutation, Mutant, Wild type, Cancer, Biology, medicine.disease_cause, medicine.disease, In vitro, Oncology, medicine, Cancer research, Kinase activity, V600E
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::edc3d4938e0112e00aa687691e13685d
https://doi.org/10.1158/1538-7445.am2011-5036 -
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المؤلفون: Lauren Puls, Wells A. Messersmith, John Frederick Boylan, Rebecca W. Powell, John J. Arcaroli, Aik Choon Tan, Arvind Dasari, Kevin Quackenbush
المصدر: Cancer Research. 71:5050-5050
مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, Angiogenesis, business.industry, Notch signaling pathway, Cancer, medicine.disease, medicine.disease_cause, Gemcitabine, medicine.anatomical_structure, Oncology, Cancer stem cell, medicine, Cancer research, Adenocarcinoma, Carcinogenesis, business, Pancreas, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9ef8fedcb4086deb137648a9596c46e7
https://doi.org/10.1158/1538-7445.am2011-5050