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1دورية أكاديمية
المؤلفون: Andre Bazzone, Maria Barthmes, Cecilia George, Nina Brinkwirth, Rocco Zerlotti, Valentin Prinz, Kim Cole, Søren Friis, Alexander Dickson, Simon Rice, Jongwon Lim, May Fern Toh, Milad Mohammadi, Davide Pau, David J. Stone, John J. Renger, Niels Fertig
المصدر: International Journal of Molecular Sciences, Vol 24, Iss 16, p 12788 (2023)
مصطلحات موضوعية: TMEM175, ion channels, Parkinson’s disease (PD), screening technologies, drug development, lysosomes, Biology (General), QH301-705.5, Chemistry, QD1-999
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Mali Liu, Guoxin Wu, Jennifer Baysarowich, Michael Kavana, George H. Addona, Kathleen K. Bierilo, John S. Mudgett, Guillaume Pavlovic, Ayesha Sitlani, John J. Renger, Brian K. Hubbard, Timothy S. Fisher, Celina V. Zerbinatti
المصدر: Journal of Lipid Research, Vol 51, Iss 9, Pp 2611-2618 (2010)
مصطلحات موضوعية: atherosclerosis, low-density lipoprotein, proprotein convertase subtilisin/kexin type 9, β-site amyloid precursor protein-cleaving enzyme 1, amyloid-β, Alzheimer's disease, Biochemistry, QD415-436
وصف الملف: electronic resource
Relation: http://www.sciencedirect.com/science/article/pii/S0022227520422916; https://doaj.org/toc/0022-2275
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3دورية أكاديمية
المؤلفون: Andres D. Ramirez, Anthony L. Gotter, Steven V. Fox, Pamela L. Tannenbaum, Lihang eYao, Spencer J. Tye, Terrence eMcDonald, Joseph eBrunner, Susan L. Garson, Duane R. Reiss, Scott D. Kuduk, Paul J. Coleman, Jason M. Uslaner, Robert eHodgson, Susan E. Browne, John J. Renger, Christopher J. Winrow
المصدر: Frontiers in Neuroscience, Vol 7 (2013)
مصطلحات موضوعية: Ethanol, Rats, Sleep, GABA, insomnia, orexin, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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المؤلفون: Jim J. Hagan, John J. Renger, Thomas S. Kilduff, Paul J. Coleman, Jerome M. Siegel, Jyrki P. Kukkonen, Christopher J. Winrow, Luis de Lecea, Daniel Hoyer, Roderick A. Porter, Anthony L. Gotter, Gregor J Sutcliffe, Neil Upton
المصدر: IUPHAR BPS Guide Pharm CITE
مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, digestive, oral, and skin physiology, Suvorexant, Lemborexant, Endogeny, Peptide, Cleavage (embryo), Article, Orexin receptor, 3. Good health, Orexin, nervous system, chemistry, mental disorders, Preproorexin, hormones, hormone substitutes, and hormone antagonists, psychological phenomena and processes
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1196f26965e8dd135a136421a8771cb
https://doi.org/10.2218/gtopdb/f51/2021.3 -
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المؤلفون: Maria I Sierra, Sridhar Duvvuri, John J. Renger, David J. Stone, Rahul Sasane, Amy Bartels, Michelle Field, David Gray, Sokhom S Pin
المصدر: J Clin Invest
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Adolescent, Urology, Prostatic Hyperplasia, Disease, 03 medical and health sciences, Terazosin, 0302 clinical medicine, Tamsulosin, medicine, Doxazosin, Humans, Alfuzosin, Aged, Aged, 80 and over, business.industry, Incidence, Neurodegeneration, Antagonist, Parkinson Disease, General Medicine, Hyperplasia, Middle Aged, medicine.disease, 030104 developmental biology, 030220 oncology & carcinogenesis, Adrenergic alpha-1 Receptor Antagonists, Commentary, business, medicine.drug, Follow-Up Studies
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المؤلفون: Laura A. Grafe, Anthony L. Gotter, Sandra Luz, Darrell Eacret, Chris J. Winrow, John J. Renger, Seema Bhatnagar
المصدر: Neuroscience. 348:313-323
مصطلحات موضوعية: Male, Restraint, Physical, 0301 basic medicine, Hypothalamo-Hypophyseal System, medicine.medical_specialty, Pituitary-Adrenal System, Endogeny, Adrenocorticotropic hormone, Article, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, Adrenocorticotropic Hormone, Orexin Receptors, Internal medicine, mental disorders, medicine, Animals, Habituation, Habituation, Psychophysiologic, Receptor, Neurons, Orexins, General Neuroscience, Antagonist, Orexin receptor, Rats, Orexin, 030104 developmental biology, Endocrinology, nervous system, Orexin Receptor Antagonists, Psychology, Stress, Psychological, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22314aabe4cd18431fa760166ee93084
https://doi.org/10.1016/j .neuroscience.2017.02.038 -
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المؤلفون: John J. Renger, Anthony L. Gotter, Christopher J. Winrow, Paul J. Coleman, W. Joseph Herring
المصدر: Annual Review of Pharmacology and Toxicology. 57:509-533
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Toxicology, Doras, Non-rapid eye movement sleep, Protein Structure, Secondary, 03 medical and health sciences, 0302 clinical medicine, Orexin Receptors, Sleep Initiation and Maintenance Disorders, Drug Discovery, mental disorders, medicine, Animals, Humans, biology, business.industry, Suvorexant, Azepines, Triazoles, medicine.disease, biology.organism_classification, Orexin receptor, Orexin, 030104 developmental biology, nervous system, Sleep Aids, Pharmaceutical, Orexin Receptor Antagonists, Wakefulness, Sleep onset, business, psychological phenomena and processes, 030217 neurology & neurosurgery, Narcolepsy
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f03b823bb14ac4fe502377dc24ac029
https://doi.org/10.1146/annurev-pharmtox-010716-104837 -
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المؤلفون: John J. Renger, Tiffany Montevideo Whitney, Michael K. Pugsley, Simon Authier, Matthew M. Abernathy, Michael J. Curtis
مصطلحات موضوعية: Clinical trial, Risk analysis (engineering), Drug development, Computer science, New chemical entity, Safety pharmacology, Liability, Relevance (law), Resolution (logic), Adverse effect
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9f843c7659b2285e92158ac51f9ba3c4
https://doi.org/10.1016/b978-0-12-812206-8.00015-7 -
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المؤلفون: Kausik K. Nanda, Yang Yuan, Celina Zerbinatti, Zhongguo Chen, Yingjie Li, Rada Vanessa L, Zhenhua Wu, Jeanine E. Ballard, Meissner Robert S, D. Jonathan Bennett, Mark T. Bilodeau, Edward J. Brnardic, Jian Li, Jill W. Maxwell, Shawn J. Stachel, Michael T. Rudd, Mali Cosden, Peter Wuelfing, Marie A. Holahan, Andrew J. Cooke, Peter Szczerba, Maria S. Michener, Jun Lu, John J. Renger, Keith Wessner, Daniel J. Klein, Victor N. Uebele, Sokreine Suon, Jason M. Uslaner, Yuntae Kim, Jillian DiMuzio, Gopal Parthasarathy, Xavier Fradera
المصدر: Journal of Medicinal Chemistry. 59:3489-3498
مصطلحات موضوعية: 0301 basic medicine, Agonist, Apolipoprotein E, medicine.medical_specialty, medicine.drug_class, Mice, Transgenic, Pharmacology, 01 natural sciences, Madin Darby Canine Kidney Cells, Mice, 03 medical and health sciences, Apolipoproteins E, Dogs, Cerebrospinal fluid, Piperidines, Alzheimer Disease, In vivo, Internal medicine, Drug Discovery, medicine, Animals, Humans, Liver X receptor, Liver X Receptors, Amyloid beta-Peptides, medicine.diagnostic_test, 010405 organic chemistry, Chemistry, Brain, Transporter, Hep G2 Cells, Orphan Nuclear Receptors, Lipids, Macaca mulatta, 0104 chemical sciences, 3. Good health, 030104 developmental biology, Endocrinology, Liver, Pharmacodynamics, Benzamides, Molecular Medicine, ATP-Binding Cassette Transporters, lipids (amino acids, peptides, and proteins), Lipid profile, Locomotion
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المؤلفون: Anthony L. Gotter, Lindsay Clark, Charles M. Harrell, Thomas H. Scheuermann, Christopher J. Winrow, Paul J. Coleman, Chad A. Brautigam, Anthony J. Roecker, Zhenhua Shao, Kerim Babaoglu, Jie Yin, John J. Renger, Daniel M. Rosenbaum
المصدر: Nature Structural & Molecular Biology. 23:293-299
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Pyrrolidines, Protein Conformation, Class C GPCR, Plasma protein binding, Crystallography, X-Ray, Ligands, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Orexin Receptors, Structural Biology, Humans, Molecular Biology, G protein-coupled receptor, Drug discovery, Mechanism (biology), Chemistry, Antagonist, Azepines, Triazoles, Orexin receptor, Cell biology, Thiazoles, 030104 developmental biology, Orexin Receptor Antagonists, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery, Protein Binding