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المؤلفون: Patrick Shum, Thomas Licher, John L. Kane, Carolin Gerbeth-Kreul, Gerhard Hessler, Antje Pommereau, Sven Ruf, Christian Engel, Linli Wei, Joerg Czech, Theresa A Kuntzweiler
المصدر: SLAS Discovery. 26:783-797
مصطلحات موضوعية: 0301 basic medicine, Chemistry, Biological membrane, Transporter, Biochemistry, Small molecule, Analytical Chemistry, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Membrane, Direct assay, Biological target, Biophysics, Molecular Medicine, Amino acid transporter, Patch clamp, 030217 neurology & neurosurgery, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::44e4fb083c4e35d492c537df0250e79a
https://doi.org/10.1177/24725552211011180 -
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المؤلفون: Carolin, Gerbeth-Kreul, Antje, Pommereau, Sven, Ruf, John L, Kane, Theresa, Kuntzweiler, Gerhard, Hessler, Christian K, Engel, Patrick, Shum, LinLi, Wei, Joerg, Czech, Thomas, Licher
المصدر: SLAS discovery : advancing life sciences RD. 26(6)
مصطلحات موضوعية: Patch-Clamp Techniques, Cell Membrane, Reproducibility of Results, Biological Transport, CHO Cells, Electrophysiological Phenomena, High-Throughput Screening Assays, Small Molecule Libraries, Mice, Amino Acid Transport Systems, Neutral, Cricetulus, Animals, Humans, Biological Assay
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b9160baf68ccf7faf0016023ba5f4dc1
https://pubmed.ncbi.nlm.nih.gov/33955247 -
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المؤلفون: Matija Zelic, Jose Sancho, Yi Li, Nellwyn Hagan, Oleg Butovsky, John L. Kane, Lisa Woodworth, Andrew Scholte, Charlotte Madore, Michael Kothe, Barbara Gisevius, Dimitry Ofengeim, Jacqueline Saleh, Jonathan Proto, Deepak Grover, Maria Fitzgerald, Aiden Haghikia, Jinyu Liu, Amy Mahan
المصدر: Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 10, Pp 1-25 (2020)مصطلحات موضوعية: Cancer Research, Encephalomyelitis, Autoimmune, Experimental, Multiple Sclerosis, Physiology, medicine.medical_treatment, Immunology, Central nervous system, Article, Cellular and Molecular Neuroscience, Mice, medicine, Demyelinating disease, Animals, Humans, lcsh:QH573-671, Neuroinflammation, Cell Proliferation, Inflammation, Microglia, business.industry, lcsh:Cytology, Multiple sclerosis, Macrophages, Experimental autoimmune encephalomyelitis, Neurodegeneration, Cell Biology, medicine.disease, Disease Models, Animal, medicine.anatomical_structure, Cytokine, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, Cancer research, business, Signal Transduction
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المؤلفون: John L. Kane, Junkai Liao, Kevin D. Noson, Gary Asmussen, Yibin Xiang, Maria Fitzgerald, Christine Klaus, Bradford H. Hirth, Michael Booker, Christopher Yee
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:4550-4554
مصطلحات موضوعية: Clinical Biochemistry, Drug Evaluation, Preclinical, Sphingosine kinase, Pharmaceutical Science, Lithium, Biochemistry, chemistry.chemical_compound, In vivo, Drug Discovery, Animals, Humans, Enzyme Inhibitors, Molecular Biology, ADME, chemistry.chemical_classification, Sphingosine, biology, Organic Chemistry, In vitro, Rats, Phosphotransferases (Alcohol Group Acceptor), Enzyme, chemistry, Sphingosine kinase 1, Enzyme inhibitor, Benzaldehydes, Microsomes, Liver, biology.protein, Molecular Medicine
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المؤلفون: Kevin M. Shea, Aimee L. Crombie, Rick L. Danheiser, John L. Kane
المصدر: Organic Letters. 3:1081-1084
مصطلحات موضوعية: Annulation, Molecular Structure, Chemistry, Antiulcer drug, Anti-Inflammatory Agents, Non-Steroidal, Organic Chemistry, chemistry.chemical_element, Benzene, Ketones, Anti-Ulcer Agents, Ring (chemistry), Biochemistry, Combinatorial chemistry, Azulenes, Rhodium, Suzuki reaction, Intramolecular force, Humans, Cycloheptanes, Physical and Theoretical Chemistry, Sesquiterpenes, Trifluoromethanesulfonate, Carbenoid
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المؤلفون: Gary Asmussen, Yibin Xiang, John L. Kane, Bradford H. Hirth, Christopher Yee, Kevin D. Noson, Michael Booker, Junkai Liao
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:6119-6121
مصطلحات موضوعية: Ceramide, PLCD3, Proline, Clinical Biochemistry, Sphingosine kinase, Pharmaceutical Science, Biochemistry, chemistry.chemical_compound, Sphingosine, Cell Line, Tumor, Drug Discovery, Homoserine, Humans, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, biology, Aminobutyrates, Organic Chemistry, Lipid signaling, Phosphotransferases (Alcohol Group Acceptor), Enzyme, chemistry, Sphingosine kinase 1, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Lysophospholipids
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المؤلفون: C. Ho, R. Fang, T. Gladysheva, N. Moran, A. Vardanyan, A. Bourque, Gloria Matthews, D. Blasioli, R. Dagher, Dinesh S. Bangari, C.R. Flannery, John L. Kane, M. Philbrook, M. Santos, K. Donahue
المصدر: Osteoarthritis and Cartilage. 23:A45-A46
مصطلحات موضوعية: Rheumatology, business.industry, Anesthesia, Joint pain, Biomedical Engineering, medicine, Orthopedics and Sports Medicine, Tropomyosin receptor kinase A, medicine.symptom, business
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المؤلفون: Rick L. Danheiser, Kevin M. Shea, Aimee L. Crombie, John L. Kane
المصدر: ChemInform. 32
مصطلحات موضوعية: Annulation, Suzuki reaction, Chemistry, Antiulcer drug, Intramolecular force, chemistry.chemical_element, Organic chemistry, General Medicine, Ring (chemistry), Combinatorial chemistry, Carbenoid, Trifluoromethanesulfonate, Rhodium
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المؤلفون: Kevin M. Shea, John L. Kane, Aimee L. Crombie, Rick L. Danheiser
المصدر: ChemInform. 36
مصطلحات موضوعية: Annulation, Transition metal, Chemistry, Polymer chemistry, Halide, General Medicine, Ring (chemistry), Coupling reaction