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المؤلفون: Lisette P. Yco, Tannya R. Ibarra-Rivera, John Opoku-Ansah, André S. Bachmann, Sudhakar Ambadi, Chia-en A. Chang, Michael C. Pirrung, Christopher C. Roberts
المصدر: Bachmann, André S; Opoku-Ansah, John; Ibarra-Rivera, Tannya R; Yco, Lisette P; Ambadi, Sudhakar; Roberts, Christopher C; et al.(2016). Syrbactin Structural Analog TIR-199 Blocks Proteasome Activity And Induces Tumor Cell Death.. The Journal of biological chemistry. UC Office of the President: Cancer Research Coordinating Committee (CRCC). Retrieved from: http://www.escholarship.org/uc/item/17k970vv
مصطلحات موضوعية: Proteasome Endopeptidase Complex, Mice, Nude, Biology, Pharmacology, 01 natural sciences, Biochemistry, Ixazomib, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Neuroblastoma, medicine, Animals, Humans, Molecular Biology, Multiple myeloma, 010405 organic chemistry, Bortezomib, Life Sciences, Molecular Bases of Disease, Cell Biology, medicine.disease, Xenograft Model Antitumor Assays, Carfilzomib, 0104 chemical sciences, HEK293 Cells, Proteasome, chemistry, Cell culture, 030220 oncology & carcinogenesis, Proteasome inhibitor, Cattle, Multiple Myeloma, Proteasome Inhibitors, medicine.drug
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5b14c77794f4ecbdb56a71ba195926
https://doi.org/10.1074/jbc.m115.710053 -
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المؤلفون: John Opoku-Ansah, Dirk Geerts, Joanna E. Gawecka, Randal K. Wada, Maisel J. Caliva, André S. Bachmann, Florian J. Sulzmaier, Jan Koster, Joe W. Ramos
المساهمون: Other departments, Oncogenomics, Hematology laboratory
المصدر: International journal of cancer. Journal international du cancer, 131(7), 1556-1568. Wiley-Liss Inc.
Gawecka, J E, Geerts, D, Koster, J, Caliva, M J, Sulzmaier, F J, Opoku-Ansah, J, Wada, R K, Bachmann, A S & Ramos, J W 2012, ' PEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastoma ', International Journal of Cancer, vol. 131, no. 7, pp. 1556-68 . https://doi.org/10.1002/ijc.27415
International Journal of Cancer, 131(7), 1556-68. Wiley-Liss Inc.مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Integrins, Motility, Biology, N-Myc Proto-Oncogene Protein, Ribosomal Protein S6 Kinases, 90-kDa, Article, Neuroblastoma, Cell Movement, Cell Line, Tumor, Chlorocebus aethiops, medicine, Cell Adhesion, Animals, Humans, RNA, Messenger, Extracellular Signal-Regulated MAP Kinases, Chromosome Aberrations, Oncogene Proteins, Gene Amplification, Intracellular Signaling Peptides and Proteins, Nuclear Proteins, Cell migration, medicine.disease, Phosphoproteins, Prognosis, Minimal residual disease, Neuroblastic Tumor, Molecular biology, Oncology, Cell culture, COS Cells, Apoptosis Regulatory Proteins, Protein Binding
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المصدر: Pharmaceutical Biology. 50:25-29
مصطلحات موضوعية: Cell Survival, Pharmaceutical Science, Antineoplastic Agents, Biology, Peptides, Cyclic, Bortezomib, Neuroblastoma, Cell Line, Tumor, Drug Discovery, medicine, Pseudomonas syringae, Humans, Urea, Viability assay, Cell Proliferation, Pharmacology, Dose-Response Relationship, Drug, General Medicine, Boronic Acids, Pediatric cancer, Virology, Complementary and alternative medicine, Proteasome, Cell culture, Pyrazines, Cancer cell, Proteasome inhibitor, Cancer research, Molecular Medicine, Multiple Myeloma, Proteasome Inhibitors, medicine.drug
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المؤلفون: Michael C. Pirrung, Sudhakar Ambadi, John Opoku-Ansah, Tannya R. Ibarra-Rivera, André S. Bachmann
المصدر: Tetrahedron. 67:9950-9956
مصطلحات موضوعية: Syringolin B, Natural product, Chemistry, Drug discovery, Stereochemistry, Organic Chemistry, Total synthesis, Biochemistry, chemistry.chemical_compound, Proteasome, Drug Discovery, Proteasome inhibitor, medicine, Lactam, Cytotoxicity, medicine.drug
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المؤلفون: Ilsa Coleman, Robert L. Vessella, Douglas S. Darling, Colm Morrissey, Michael S. Hwang, Eva Corey, Alexander M. Bailey, Holly M. Nguyen, Peter S. Nelson, Aaron P. Putzke, Beatrice S. Knudsen, Muneesh Tewari, Muge Celiktas, Aviva P. Ventura, John Opoku-Ansah, Canan Akture
المصدر: The American Journal of Pathology. 179:400-410
مصطلحات موضوعية: Matrigel, Pathology, medicine.medical_specialty, Cadherin, Cancer, Biology, medicine.disease, Isogenic human disease models, Pathology and Forensic Medicine, Metastasis, Prostate cancer, DU145, Cancer research, medicine, Epithelial–mesenchymal transition
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المؤلفون: Maisel J. Caliva, John Opoku-Ansah, Joe W. Ramos, Erin L. Filbert, Florian J. Sulzmaier, Andrey S. Shaw, Hemamalini Renganathan, Joanna E. Gawecka, Guy Werlen, Sandra Pastorino
المصدر: The FASEB Journal. 24:2818-2828
مصطلحات موضوعية: Interleukin 2, MAPK/ERK pathway, T-Lymphocytes, T cell, Active Transport, Cell Nucleus, Receptors, Antigen, T-Cell, Biochemistry, Jurkat cells, Research Communications, Jurkat Cells, Mice, Genetics, medicine, Animals, Humans, FADD, Extracellular Signal-Regulated MAP Kinases, Molecular Biology, Cell Proliferation, Mice, Knockout, biology, Effector, food and beverages, Phosphoproteins, Molecular biology, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, biology.protein, Interleukin-2, Death effector domain, Signal transduction, Apoptosis Regulatory Proteins, Signal Transduction, Biotechnology, medicine.drug
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المؤلفون: Joe W. Ramos, Florian J. Sulzmaier, John Opoku-Ansah
المصدر: Small GTPases. 3(3)
مصطلحات موضوعية: Models, Molecular, MAP Kinase Signaling System, Regulator, Plasma protein binding, Biology, Biochemistry, law.invention, Phosphorylation cascade, law, Anti-apoptotic Ras signalling cascade, Neoplasms, Animals, Humans, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, Cell growth, Intracellular Signaling Peptides and Proteins, food and beverages, Cell Biology, Phosphoproteins, Cell biology, Phosphoprotein, Commentary, Suppressor, Apoptosis Regulatory Proteins, Protein Binding
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المؤلفون: Joe W. Ramos, John Opoku-Ansah, Hema Vaidyanathan, Sandra Pastorino, Hema Renganathan, Michelle L. Matter
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 104(50)
مصطلحات موضوعية: MAPK/ERK pathway, MAP Kinase Signaling System, Biology, Ribosomal Protein S6 Kinases, 90-kDa, Substrate Specificity, Enzyme activator, Mice, Transcription (biology), Chlorocebus aethiops, Extracellular, Animals, Humans, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, Cells, Cultured, Mice, Knockout, Multidisciplinary, COS cells, Intracellular Signaling Peptides and Proteins, food and beverages, Biological Sciences, Phosphoproteins, Molecular biology, Cell biology, Enzyme Activation, Phosphoprotein, COS Cells, Signal transduction, Apoptosis Regulatory Proteins, HeLa Cells, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0bcfe0f38a2612a42275ac7c3fe2a5
https://pubmed.ncbi.nlm.nih.gov/18077417 -
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المؤلفون: Gabor Mocz, André S. Bachmann, Lisette P. Yco, John Opoku-Ansah
المصدر: Biochemistry Insights
Biochemistry Insights, Vol 7 (2014)
Biochemistry Insights, Vol 2014, Iss 7, Pp 1-13 (2014)مصطلحات موضوعية: Programmed cell death, natural products, Bioinformatics, lcsh:Biochemistry, chemistry.chemical_compound, Neuroblastoma, medicine, signal transducer and activator of transcription 3 (STAT3), lcsh:QD415-436, STAT3, Withaferin A (WFA), Transcription factor, Original Research, biology, molecular modeling, business.industry, General Medicine, medicine.disease, multiple myeloma, pediatric cancer neuroblastoma, chemistry, Withaferin A, Cancer research, STAT protein, biology.protein, Phosphorylation, business, Proto-oncogene tyrosine-protein kinase Src