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1
المؤلفون: John P. Chism, C.E. Herron, David H. Melich, D.C. Kemp, Glenn Smith, J.S. Prescott, C.C. Brueckner, N. Oleas, Joseph W. Polli
المصدر: Toxicology and Applied Pharmacology. 289:117-123
مصطلحات موضوعية: Male, Statin, medicine.drug_class, Atorvastatin, Drug Evaluation, Preclinical, Pharmacology, Toxicology, chemistry.chemical_compound, Dogs, Toxicity Tests, Animals, Medicine, Toxicokinetics, Dosing, Dose-Response Relationship, Drug, business.industry, Cholesterol, Anticholesteremic Agents, nutritional and metabolic diseases, Drug interaction, medicine.disease, chemistry, Toxicity, Female, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitors, business, Dyslipidemia, medicine.drug
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2
المؤلفون: Katie L Olson, Stephen Castellino, Vicky R Otto, Lisa A St. John-Williams, John P. Chism, Sesha M. Woodard, Victoria E Demby, Joseph W. Polli, Russ L Yeager
المصدر: Drug Metabolism and Disposition. 37:439-442
مصطلحات موضوعية: Central Nervous System, Male, Abcg2, Receptor, ErbB-2, medicine.drug_class, Pharmaceutical Science, Antineoplastic Agents, Breast Neoplasms, Pharmacology, Lapatinib, Blood–brain barrier, Tyrosine-kinase inhibitor, Mice, Cricetinae, medicine, Animals, Humans, Tissue Distribution, ATP Binding Cassette Transporter, Subfamily B, Member 1, skin and connective tissue diseases, Receptor, Protein Kinase Inhibitors, P-glycoprotein, Mice, Knockout, biology, Brain, Biological Transport, Drug Synergism, Disease Models, Animal, medicine.anatomical_structure, Blood-Brain Barrier, Area Under Curve, Knockout mouse, Quinazolines, biology.protein, ATP-Binding Cassette Transporters, Female, Tyrosine kinase, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c446a3c6fcae4c9e67c673f5631417
https://doi.org/10.1124/dmd.108.024646 -
3
المؤلفون: Derek J. Nunez, John P. Chism, Christopher J. Gruenloh, Georgios Vlasakakis, Jiang Lin, Xiaozhou Yao, Susan L. Johnson
المصدر: Advances in therapy. 32(7)
مصطلحات موضوعية: Drug, Insulin pump, Male, media_common.quotation_subject, Pharmacology, Infusions, Subcutaneous, Insulin Infusion Systems, Pharmacokinetics, Medicine, Humans, Hypoglycemic Agents, Pharmacology (medical), media_common, Dose-Response Relationship, Drug, business.industry, Venoms, Type 2 Diabetes Mellitus, General Medicine, Drug development, Tolerability, Diabetes Mellitus, Type 2, Cohort, Exenatide, Female, business, Peptides, medicine.drug, Half-Life
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4
المؤلفون: J. Sigafoos, J. J. Conde, Parul Patel, Phuong Huynh, Kathryn O’Mara, Yun Lan Yueh, John P. Chism, John F. Tomayko, Etienne Dumont, Patrick J. Stump, Milena Kurtinecz, David Tenero, Elizabeth Cunningham, Gary D. Bowers, Melinda J. Reese, Graeme Young
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 41(5)
مصطلحات موضوعية: Boron Compounds, Male, medicine.drug_class, Metabolite, Antibiotics, Pharmaceutical Science, Aldehyde dehydrogenase, Urine, Mass Spectrometry, chemistry.chemical_compound, Pharmacokinetics, medicine, Animals, Humans, Alcohol dehydrogenase, Boron, Pharmacology, chemistry.chemical_classification, Chromatography, biology, Metabolism, Anti-Bacterial Agents, Macaca fascicularis, Enzyme, chemistry, biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3aaaf8b6f639046225b82397c7b7df6
https://pubmed.ncbi.nlm.nih.gov/23439661 -
5
المصدر: Chemico-biological interactions. 89(1)
مصطلحات موضوعية: musculoskeletal diseases, Male, medicine.medical_specialty, Thyroid Hormones, animal structures, Immunoblotting, Flavin-containing monooxygenase, Reductase, Toxicology, Drug Administration Schedule, Rats, Sprague-Dawley, fluids and secretions, Internal medicine, medicine, Animals, Cytochrome P-450 Enzyme Inhibitors, Testosterone, Tissue Distribution, Cobalt Radioisotopes, NADPH-Ferrihemoprotein Reductase, biology, Flavoproteins, Chemistry, Cytochrome P450, Biological activity, Rats, Inbred Strains, General Medicine, Monooxygenase, musculoskeletal system, Rats, carbohydrates (lipids), Endocrinology, Mesoporphyrins, biology.protein, Microsomes, Liver, Rabbits, Benzphetamine, Drug metabolism, medicine.drug
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6
المؤلفون: John P. Chism, Douglas E. Rickert, William F. Greenlee
المصدر: Analytical Biochemistry. 112:367-370
مصطلحات موضوعية: Male, Catechols, Biophysics, Ascorbic Acid, Biochemistry, High-performance liquid chromatography, chemistry.chemical_compound, Phenols, Biotransformation, Bone Marrow, Animals, Phenol, Benzene, Molecular Biology, Chromatography, High Pressure Liquid, Chromatography, Hydroquinone, Cell Biology, Hydrogen-Ion Concentration, Ascorbic acid, Hydroquinones, Rats, Liver, chemistry, Polyphenol
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7
المؤلفون: John P. Chism, Douglas E. Rickert
المصدر: Chemical Research in Toxicology. 2:150-156
مصطلحات موضوعية: Male, Sulfotransferase, Metabolite, Phosphoadenosine Phosphosulfate, Alcohol, In Vitro Techniques, Toxicology, chemistry.chemical_compound, Cytosol, Acetyl Coenzyme A, Acetyltransferases, Animals, Benzyl Alcohols, Biotransformation, Chromatography, High Pressure Liquid, Cell Nucleus, chemistry.chemical_classification, Hydrolysis, General Medicine, Rats, Inbred F344, Rats, Dinitrobenzenes, Enzyme, chemistry, Biochemistry, Microsomes, Liver, Microsome, Nucleic acid, Acyltransferases, NADP, DNA, Toluene
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1fb993aa69eaaa5b42a73b368344a5
https://doi.org/10.1021/tx00009a005 -
8Induction of hepatic and testicular lesions in fischer-344 rats by single oral doses of nitrobenzene
المؤلفون: James A. Bond, John P. Chism, Douglas E. Rickert, James A. Popp
المصدر: Fundamental and Applied Toxicology. 1:389-394
مصطلحات موضوعية: Male, medicine.medical_specialty, Pathology, Necrosis, Administration, Oral, Biology, Toxicology, Methemoglobinemia, Muscle hypertrophy, chemistry.chemical_compound, Internal medicine, Testis, medicine, Animals, Sodium nitrite, Methemoglobin, Nitrobenzenes, Epididymis, medicine.disease, Rats, Inbred F344, Acute toxicity, Rats, Endocrinology, medicine.anatomical_structure, Seminiferous tubule, Liver, chemistry, Giant cell, medicine.symptom
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9
المؤلفون: John P. Chism, Douglas E. Rickert, Gregory L. Kedderis
المصدر: Biological Reactive Intermediates III ISBN: 9781468451368
مصطلحات موضوعية: Sulfotransferase, chemistry.chemical_compound, DNA synthesis, Biochemistry, Chemistry, medicine, Microsome, Alcohol, Metabolism, Glucuronide, medicine.disease_cause, Glucuronic acid, Genotoxicity
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::75f8e40af470ae0923101a033a72c038
https://doi.org/10.1007/978-1-4684-5134-4_53 -
10
المؤلفون: Douglas E. Rickert, John P. Chism, Terrie S. Baker
المصدر: Environmental Health Perspectives
مصطلحات موضوعية: Male, Chemistry, Health, Toxicology and Mutagenesis, Metabolite, Public Health, Environmental and Occupational Health, Benzene, Disposition, Pharmacology, Rats, Inbred F344, Rats, chemistry.chemical_compound, Kinetics, Adipose Tissue, Bone Marrow, Bone Marrow Diseases, Animals, Site of action, Biotransformation, Research Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a9e6a67e0db344f10fc8459bcef09d
https://pubmed.ncbi.nlm.nih.gov/7238454