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1دورية أكاديمية
المؤلفون: Simon R. Green, Susan H. Davis, Sebastian Damerow, Curtis A. Engelhart, Michael Mathieson, Beatriz Baragaña, David A. Robinson, Jevgenia Tamjar, Alice Dawson, Fabio K. Tamaki, Kirsteen I. Buchanan, John Post, Karen Dowers, Sharon M. Shepherd, Chimed Jansen, Fabio Zuccotto, Ian H. Gilbert, Ola Epemolu, Jennifer Riley, Laste Stojanovski, Maria Osuna-Cabello, Esther Pérez-Herrán, María José Rebollo, Laura Guijarro López, Patricia Casado Castro, Isabel Camino, Heather C. Kim, James M. Bean, Navid Nahiyaan, Kyu Y. Rhee, Qinglan Wang, Vee Y. Tan, Helena I. M. Boshoff, Paul J. Converse, Si-Yang Li, Yong S. Chang, Nader Fotouhi, Anna M. Upton, Eric L. Nuermberger, Dirk Schnappinger, Kevin D. Read, Lourdes Encinas, Robert H. Bates, Paul G. Wyatt, Laura A. T. Cleghorn
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2دورية أكاديمية
المؤلفون: Vitor Mendes, Simon R. Green, Joanna C. Evans, Jeannine Hess, Michal Blaszczyk, Christina Spry, Owain Bryant, James Cory-Wright, Daniel S-H. Chan, Pedro H. M. Torres, Zhe Wang, Navid Nahiyaan, Sandra O’Neill, Sebastian Damerow, John Post, Tracy Bayliss, Sasha L. Lynch, Anthony G. Coyne, Peter C. Ray, Chris Abell, Kyu Y. Rhee, Helena I. M. Boshoff, Clifton E. Barry, Valerie Mizrahi, Paul G. Wyatt, Tom L. Blundell
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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3دورية أكاديمية
المؤلفون: Ohm Prakash, Jana Führing, John Post, Sharon M. Shepherd, Thomas C. Eadsforth, David Gray, Roman Fedorov, Françoise H. Routier
المصدر: Molecules, Vol 24, Iss 5, p 996 (2019)
مصطلحات موضوعية: UDP-sugar pyrophosphorylase, allosteric inhibitor, inhibitor scaffold, library screen, Organic chemistry, QD241-441
وصف الملف: electronic resource
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المؤلفون: Myong Gyu, Kim, Trine, Gulholm, Kate, Lennard, Feras, Mirdad, Kristen, Overton, Michael, Maley, Pamela, Konecny, David, Andresen, Jeffrey John, Post
المصدر: Journal of medical virologyREFERENCES. 95(1)
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المؤلفون: Paul G. Wyatt, Peter C. Ray, Kyu Y. Rhee, Sasha L. Lynch, Valerie Mizrahi, Clifton E. Barry, John Post, Helena I. Boshoff, Navid Nahiyaan, Anthony G. Coyne, Tom L. Blundell, Joanna C. Evans, Christina Spry, Dinakaran Murugesan, Vitor Mendes, Simon Green, Jeannine Hess, Stephen Thompson, Chris Abell, Zhe Wang
المساهمون: Evans, Joanna C [0000-0002-4139-9527], Mendes, Vitor [0000-0002-2734-2444], Green, Simon R [0000-0001-5054-4792], Spry, Christina [0000-0002-8156-7070], Coyne, Anthony G [0000-0003-0205-5630], Abell, Chris [0000-0001-9174-1987], Boshoff, Helena IM [0000-0002-4333-206X], Wyatt, Paul G [0000-0002-0397-245X], Mizrahi, Valerie [0000-0003-4824-9115], Apollo - University of Cambridge Repository
المصدر: ACS Infectious Diseases
مصطلحات موضوعية: 0301 basic medicine, Coenzyme A, 030106 microbiology, Druggability, Article, Cofactor, Pantothenic Acid, drug discovery, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, In vivo, Cysteine, Peptide Synthases, biology, Drug discovery, Chemistry, biology.organism_classification, Small molecule, In vitro, 3. Good health, 030104 developmental biology, Infectious Diseases, Biochemistry, tuberculosis, biology.protein, CoaBC
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b118e20c165cc2ee3aa60e19f743440
https://www.repository.cam.ac.uk/handle/1810/322238 -
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المؤلفون: Laifeng Ding, Robert L. Peach, Uwais Mufti, Leandro Castellano, Dan Leibovici, J. Mark Skehel, Francesco Mauri, Lucksamon Thamlikitkul, Joel Abrahams, Lucinda Billingham, Christopher I. Moore, David J. Pinato, Mauricio Barahona, Rajat Roy, Mathias Winkler, Michael J. Seckl, Julian Downward, Neil Steven, Michael Cullen, Georgios Giamas, Philip Cohen, Sophia N. Yaliraki, Olivier E. Pardo, Seth J. Salpeter, David C. Hancock, Miriam Molina-Arcas, Stelios Chrysostomou, Silvia Ottaviani, David Hrouda, Yulan Wang, Kathryn L. Chapman, Shay Golan, Devmini Moonamale, Adi Zundelevich, Romain Lara, Jennifer Pascoe, Maruf M.U. Ali, David R. Klug, Vered Bar, Filippo Prischi, Sarah Pirrie, Claire Gaunt, John Post
المساهمون: Cancer Treatment & Research Trust, IP2IPO Innovations Limited, Cancer Research UK, Engineering & Physical Science Research Council (EPSRC), Engineering and Physical Sciences Research Council
المصدر: Sci Transl Med
مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, medicine.medical_treatment, Drug resistance, Ribosomal Protein S6 Kinases, 90-kDa, Article, Metastasis, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, Cell Line, Tumor, medicine, Gene silencing, Animals, Humans, Lung cancer, Lung, 11 Medical and Health Sciences, Chemotherapy, Bladder cancer, business.industry, General Medicine, 06 Biological Sciences, medicine.disease, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Urinary Bladder Neoplasms, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, business, Ex vivo
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652437ab75168eac8df4c7cdc12b7c5f
http://hdl.handle.net/10044/1/90380 -
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المؤلفون: Clifton E. Barry, Paul G. Wyatt, Sasha L. Lynch, Pedro Henrique Monteiro Torres, Daniel Shiu-Hin Chan, Simon Green, Helena I. Boshoff, Joanna C. Evans, Vitor Mendes, Kyu Y. Rhee, James Cory-Wright, Michal Blaszczyk, Peter C. Ray, Valerie Mizrahi, Sebastian Damerow, Navid Nahiyaan, Anthony G. Coyne, John Post, Tom L. Blundell, Tracy Bayliss, Sandra O’Neill, Chris Abell, Jeannine Hess, Christina Spry, Zhe Wang, Owain J. Bryant
المساهمون: Mendes, Vitor [0000-0002-2734-2444], Hess, Jeannine [0000-0001-5916-0728], Spry, Christina [0000-0002-8156-7070], Coyne, Anthony G. [0000-0003-0205-5630], Abell, Chris [0000-0001-9174-1987], Rhee, Kyu Y. [0000-0003-4582-2895], Boshoff, Helena I. M. [0000-0002-4333-206X], Barry, Clifton E. [0000-0002-2927-270X], Blundell, Tom L. [0000-0002-2708-8992], Apollo - University of Cambridge Repository, Coyne, Anthony G [0000-0003-0205-5630], Rhee, Kyu Y [0000-0003-4582-2895], Boshoff, Helena IM [0000-0002-4333-206X], Barry, Clifton E [0000-0002-2927-270X], Blundell, Tom L [0000-0002-2708-8992]
المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)مصطلحات موضوعية: 0301 basic medicine, Carboxy-Lyases, 45/41, ved/biology.organism_classification_rank.species, Antitubercular Agents, General Physics and Astronomy, Crystallography, X-Ray, 01 natural sciences, chemistry.chemical_compound, Peptide Synthases, Multidisciplinary, biology, Drug discovery, Mycobacterium smegmatis, 3. Good health, Enzymes, Biochemistry, Gene Knockdown Techniques, Allosteric Site, Tuberculosis, 145, Science, Coenzyme A, Allosteric regulation, Microbial Sensitivity Tests, General Biochemistry, Genetics and Molecular Biology, Article, Mycobacterium tuberculosis, 03 medical and health sciences, Biosynthesis, Allosteric Regulation, Bacterial Proteins, medicine, Humans, Model organism, 82/83, X-ray crystallography, Enzyme Assays, 49/98, 010405 organic chemistry, ved/biology, 631/154, General Chemistry, biology.organism_classification, medicine.disease, 0104 chemical sciences, High-Throughput Screening Assays, Metabolic pathway, 030104 developmental biology, chemistry, 631/535/1266, 631/45/607
وصف الملف: application/pdf; application/zip; text/xml
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المؤلفون: John Post, Dennis Silage
المصدر: 2018 ASEE Annual Conference & Exposition Proceedings.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fd75498f402f6929b663154a4ee5e36e
https://doi.org/10.18260/1-2--30647 -
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المؤلفون: David W. Gray, David A. Robinson, Sharon M. Shepherd, Darren Edwards, Claire J. MacKenzie, Michael G. Thomas, Ian H. Gilbert, Judith V. Hobrath, Leah S. Torrie, Rafael Ferreira, Alan H. Fairlamb, Manu De Rycker, Eun-Jung Ko, John Post, Karolina Wrobel
المصدر: ACS Infectious Diseases
مصطلحات موضوعية: 0301 basic medicine, 030106 microbiology, Allosteric regulation, Trypanosoma brucei brucei, Protozoan Proteins, Methionine-tRNA Ligase, Trypanosoma brucei, Article, drug discovery, allosteric, 03 medical and health sciences, Methionine, parasitic diseases, Homology modeling, Binding site, Trypanosoma cruzi, chemistry.chemical_classification, Leishmania, biology, Chemistry, Drug discovery, methionyl-tRNA synthetase, biology.organism_classification, 3. Good health, inhibitor, 030104 developmental biology, Infectious Diseases, Enzyme, Biochemistry, kinetoplastid, Allosteric Site
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المؤلفون: Zhe Wang, Valerie Mizrahi, Christina Spry, Kyu Y. Rhee, Sebastian Damerow, John Post, Owain J. Bryant, James Cory-Wright, Sasha L. Lynch, Sandra O’Neill, Tracy Bayliss, Michal Blaszczyk, Paul G. Wyatt, Clifton E. Barry, Pedro Henrique Monteiro Torres, Jeannine Hess, Peter C. Ray, Vitor Mendes, Tom L. Blundell, Simon Green, Chris Abell, Joanna C. Evans, Helena I. Boshoff, Daniel S-H. Chan, Anthony G. Coyne
مصطلحات موضوعية: 0303 health sciences, Tuberculosis, biology, Chemistry, ved/biology, Coenzyme A, Mycobacterium smegmatis, 030302 biochemistry & molecular biology, Allosteric regulation, ved/biology.organism_classification_rank.species, biology.organism_classification, medicine.disease, 3. Good health, Mycobacterium tuberculosis, 03 medical and health sciences, Metabolic pathway, chemistry.chemical_compound, Biochemistry, Biosynthesis, medicine, Model organism, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad01cb6cb3beb75dc60f063a9f3eaf83