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المؤلفون: Chiang Yu, Gregory Vite, Simone Oppenheimer, Derek Norris, Harold Malone, Anne Lewin, Daniel Kukral, Bala Krishnan, John T. Hunt, Christine Hilt, Benjamin Henley, Amy Hammell, Ashvinikumar Gavai, Brian Fink, Joseph Fargnoli, Craig Fairchild, Stuart Emanuel, Francis Y. Lee, Tai W. Wong
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f909ef46a03d1570a27d99c5261e2b
https://doi.org/10.1158/1078-0432.22441917.v1 -
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المؤلفون: Chiang Yu, Gregory Vite, Simone Oppenheimer, Derek Norris, Harold Malone, Anne Lewin, Daniel Kukral, Bala Krishnan, John T. Hunt, Christine Hilt, Benjamin Henley, Amy Hammell, Ashvinikumar Gavai, Brian Fink, Joseph Fargnoli, Craig Fairchild, Stuart Emanuel, Francis Y. Lee, Tai W. Wong
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33f1ae66761ffc51c82294bcb244134
https://doi.org/10.1158/1078-0432.c.6518787 -
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المؤلفون: Chiang Yu, Gregory Vite, Simone Oppenheimer, Derek Norris, Harold Malone, Anne Lewin, Daniel Kukral, Bala Krishnan, John T. Hunt, Christine Hilt, Benjamin Henley, Amy Hammell, Ashvinikumar Gavai, Brian Fink, Joseph Fargnoli, Craig Fairchild, Stuart Emanuel, Francis Y. Lee, Tai W. Wong
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10077e61e239f1a813c40834f158a23d
https://doi.org/10.1158/1078-0432.22441920 -
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المؤلفون: Jay A. Markwalder, Aaron J. Balog, David K. Williams, Susheel J. Nara, Ratnakar Reddy, Saumya Roy, Yadagiri Kanyaboina, Xin Li, Kathy Johnston, Yi Fan, Hal Lewis, Frank Marsilio, Chunhong Yan, David Critton, John A. Newitt, Sarah C. Traeger, Dauh-Rurng Wu, Maria N. Jure-Kunkel, Lata Jayaraman, Tai-An Lin, Michael W. Sinz, John T. Hunt, Steven P. Seitz
مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Molecular Biology, Biochemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f0da67b51d6c7282c418d8dbb98887
https://doi.org/10.2139/ssrn.4348735 -
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المؤلفون: Ching Kim Tye, Chunhong Yan, Sarah C. Traeger, Wayne Vaccaro, Yingru Zhang, Gerry Everlof, Jianqing Li, Henry Yip, Peng Li, John T. Hunt, Michael A. Poss, Gregory D. Vite, Mussari Christopher P, Steven Sheriff, Asoka Ranasinghe, Haiying Zhang, Richard A. Westhouse, Dharmpal S. Dodd, Richard Rampulla, Zheng Yang, Frank Marsilio, Derek J. Norris, Wen-Ching Han, Tram N. Huynh, Yufen Zhao, Patrice Gill, Nirmala Raghavan, Lalgudi S. Harikrishnan, Ashvinikumar V. Gavai, Susan Wee, John S. Tokarski, Dauh-Rurng Wu, Arvind Mathur, Mei-Li Wen, Huiping Zhang, David R. Tortolani, George V. Delucca, Krista Menard, Francis Y. Lee, Claude A. Quesnelle, Dawn Sun, Vijay T. Ahuja, Daniel O'malley, Christine Huang, Muthoni G. Kamau
المصدر: Journal of Medicinal Chemistry. 64:14247-14265
مصطلحات موضوعية: Drug, Proline, Phenylalanine, media_common.quotation_subject, Carbazoles, Administration, Oral, Antineoplastic Agents, Cell Cycle Proteins, Computational biology, BET inhibitor, Structure-Activity Relationship, Pharmacokinetics, In vivo, Drug Discovery, Transcriptional regulation, Humans, Potency, media_common, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Tryptophan, Signal transducing adaptor protein, Bromodomain, Molecular Medicine, Transcription Factors
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المؤلفون: Mark Fereshteh, Xiao Zhu, Tai-An Lin, Prabhakar Rajanna, Cherney Emily Charlotte, Aravind Anandam, Xin Li, Derrick Maley, Liping Zhang, Gopal Dhar, Aaron Balog, Robert M. Borzilleri, Johnni Gullo-Brown, T. Thanga Mariappan, Kathy Johnston-Allegretto, Christine Huang, Venkata Murali, John T. Hunt, Sandeep Mahankali, Gregory D. Vite, Lisa M. Kopcho, Shweta Padmanabhan, Sarah C. Traeger
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Metastatic melanoma, 010405 organic chemistry, business.industry, medicine.medical_treatment, Organic Chemistry, Phases of clinical research, Immunotherapy, medicine.disease, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Cancer immunotherapy, Renal cell carcinoma, Drug Discovery, medicine, Cancer research, business, Indoleamine 2,3-dioxygenase
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المؤلفون: Lisa M. Kopcho, Johnni Gullo-Brown, Shweta Padmanabhan, Pattasseri Shabeerali, Arvind Mathur, Prabhakar Rajanna, Lorell Discenza, Liping Zhang, Zhenqiu Hong, Sarah C. Traeger, Zheng Yang, Cherney Emily Charlotte, Richard Rampulla, David K. Williams, Gopal Dhar, Kimberly A. Foster, James Kempson, Derrick Maley, Mary F. Grubb, Xiao Zhu, Xin Li, Weifang Shan, Robert M. Borzilleri, Diane Delpy, Kevin Stefanski, T. Thanga Mariappan, Gregory D. Vite, Kathy A. Johnston, Audris Huang, Asoka Ranasinghe, Mark Fereshteh, Aravind Anandam, Steven P. Seitz, John T. Hunt, Aaron Balog, Celia D’Arienzo, Anuradha Gupta, Tai-An Lin, Roshan Y. Nimje, Weiwei Guo, Christine Huang, Venkata Murali, Sandeep Mahankali
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: chemistry.chemical_compound, Oxidative metabolism, chemistry, Metastatic melanoma, Mouse xenograft, Organic Chemistry, Drug Discovery, Pyridine, Quinoline, Biochemistry, Combinatorial chemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f0d7f8a891846e7ad07844b139d549
https://europepmc.org/articles/PMC8274105/ -
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المؤلفون: Steven P. Seitz, Gregory D. Vite, John T. Hunt, Mark Fereshteh, Cherney Emily Charlotte, Joseph Fargnoli, Lorell Discenza, Liping Zhang, Jennifer Brown, Xin Li, Kevin Stefanski, Christine Huang, Asoka Ranasinghe, Lisa M. Kopcho, Xiao Zhu, Aaron Balog, Diane Delpy, Sarah C. Traeger, Jesse Swanson, Mary F. Grubb, Zheng Yang, Theresa Ziemba, Kathy A. Johnston, Kimberly A. Foster, Johnni Gullo-Brown, Celia D’Arienzo, Susheel Jethanand Nara, Robert M. Borzilleri, Derrick Maley, Tai-An Lin
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: 010405 organic chemistry, business.industry, medicine.medical_treatment, Organic Chemistry, Cancer, medicine.disease, 01 natural sciences, Biochemistry, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Immune system, Cancer immunotherapy, In vivo, Renal cell carcinoma, Dioxygenase, Drug Discovery, medicine, Cancer research, Indoleamine 2,3-dioxygenase, business