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المؤلفون: Douglas A. Corley, Dan Li, Wei K. Zhao, Mary Anne Armstrong, Christopher D. Jensen, Sanjay Kakar, Debbie Postlethwaite, Greg Rumore, Theodore R. Levin, Monica Santamaria, John Woolfrey, Sheng-Fang Jiang
المصدر: Gastrointestinal endoscopy. 87(3)
مصطلحات موضوعية: Adenoma, Male, medicine.medical_specialty, Colonoscopy, California, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Medicine, Humans, Radiology, Nuclear Medicine and imaging, Aged, Retrospective Studies, Aged, 80 and over, medicine.diagnostic_test, business.industry, Gastroenterologists, Gastroenterology, Retrospective cohort study, Odds ratio, Community Health Centers, Middle Aged, medicine.disease, Confidence interval, Surgery, Pathologists, 030220 oncology & carcinogenesis, Colonic Neoplasms, 030211 gastroenterology & hepatology, Education, Medical, Continuing, Female, business, Body mass index, Cohort study, Sessile serrated adenoma
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المؤلفون: John Woolfrey, Craig Stacy Takeuchi, Arthur Plonowski, Kyoko Yamaguchi, Ron Aoyama, Byung Gyu Kim, Anagha Abhijit Joshi, Paul Foster, Sunghoon Ma, Sharmila Rajan, Tae Gon Baik, Naing Aay, Arlyn Arcalas, Charles M. Blazey, Jonah Cannoy, Peter Lamb, Isabelle Lehoux, Chris A. Buhr, Narsimha Munagala, Matthew Sangyup Lee, John M. Nuss, James W. Leahy, Jae Lee, Sergey Epshteyn, Neel Kumar Anand, Nicole Miller, Longcheng Wang, Katherine Lara, Henry Johnson
المصدر: Journal of Medicinal Chemistry. 56:2218-2234
مصطلحات موضوعية: Male, Models, Molecular, Protein Conformation, Administration, Oral, Biological Availability, Pharmacology, Binding, Competitive, Substrate Specificity, Mice, Adenosine Triphosphate, Dogs, Pharmacokinetics, Oral administration, Cell Line, Tumor, Drug Discovery, Animals, Humans, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Drug discovery, Chemistry, Kinase, TOR Serine-Threonine Kinases, Benzoxazines, Rats, Bioavailability, Cell culture, Molecular Medicine, Phosphorylation, Female
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المؤلفون: Athiwat Hutchaleelaha, Robert M. Scarborough, Penglie Zhang, Susan Edwards, Yanhong Wu, Uma Sinha, Zhaozhong J. Jia, John Woolfrey, Wenrong Huang, Stanley J. Hollennbach, Joseph L. Lambing, Ann E. Arfsten, Yonghong Song, Bing-Yan Zhu
المصدر: Bioorganic & Medicinal Chemistry Letters. 14:1229-1234
مصطلحات موضوعية: medicine.drug_mechanism_of_action, Stereochemistry, Antithrombin III, Clinical Biochemistry, Factor Xa Inhibitor, Administration, Oral, Biological Availability, Pharmaceutical Science, Pyrazole, Biochemistry, Chemical synthesis, Benzamidine, Rats, Sprague-Dawley, Amidine, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Molecular Biology, biology, Organic Chemistry, Amides, Benzamidines, Rats, chemistry, Enzyme inhibitor, Drug Design, biology.protein, Pyrazoles, Molecular Medicine
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المؤلفون: John Malinowski, John Woolfrey, Uma Sinha, Katherine Tran, Penglie Zhang, Paul W. Wong, Brian Huang, Gary Park, Jingmei Zuckett, Andrea Reed, Robert M. Scarborough, Stan Hollenbach, Bing-Yan Zhu
المصدر: Bioorganic & Medicinal Chemistry Letters. 12:1657-1661
مصطلحات موضوعية: Serine Proteinase Inhibitors, medicine.drug_mechanism_of_action, Molecular model, Stereochemistry, Clinical Biochemistry, Factor Xa Inhibitor, Administration, Oral, Biological Availability, Pharmaceutical Science, Biochemistry, Chemical synthesis, Rats, Sprague-Dawley, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Structure–activity relationship, Molecular Biology, biology, Chemistry, Organic Chemistry, Isoquinolines, Benzamidines, Combinatorial chemistry, Rats, Bioavailability, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Factor Xa Inhibitors
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المؤلفون: Robert M. Scarborough, Ting Su, John Woolfrey, Gary Park, Yanhong Wu, Zhaozhong J. Jia, Uma Sinha, Bing-Yan Zhu, Paul W. Wong, Brandon Doughan, Brian Huang
المصدر: Bioorganic & Medicinal Chemistry Letters. 11:2947-2950
مصطلحات موضوعية: Models, Molecular, Serine Proteinase Inhibitors, medicine.drug_mechanism_of_action, Molecular model, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Factor Xa Inhibitor, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, Amidine, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Molecular Biology, chemistry.chemical_classification, biology, Organic Chemistry, Amino acid, Enzyme, chemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Factor Xa Inhibitors
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المؤلفون: Matthew Sangyup Lee, Robin Tammie Noguchi, John M. Nuss, Peiwen Zu, Jeff Chen, Brian Kane, Naing Aay, Jia Li, Xian Shi, Brian Hugh Ridgway, Craig Stacy Takeuchi, Elena S. Koltun, Lisa E. Meyr, Henry Johnson, Timothy Patrick Forsyth, Sergey Epshteyn, Brown S David, Byung Gyu Kim, Stefan Engst, Adam A. Galan, Arlyn Arcalas, Gary L. Lewis, Jean-Francois Martini, Vicky Chan, Thomas J. Stout, Robert Kassees, Shwu-Hwa Lin, James W. Leahy, Wentao Zhang, Grace Mann, Philip Tong, Ron Aoyama, Patrick Kearney, Michael Pack, Peiwen Yu, Steven Brian Gendreau, Tai P. Huynh, John Woolfrey, Hongwang Du, Mohamed Abdulkader Ibrahim
المصدر: Bioorganicmedicinal chemistry letters. 22(24)
مصطلحات موضوعية: Models, Molecular, Proline, High-throughput screening, Clinical Biochemistry, Pharmaceutical Science, Mice, Nude, Antineoplastic Agents, Apoptosis, Pharmacology, Crystallography, X-Ray, Biochemistry, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Dogs, Mouse xenograft, In vivo, Drug Discovery, High-Throughput Screening Assays, Structure–activity relationship, Animals, Molecular Biology, Protein Kinase Inhibitors, Cell Proliferation, Janus kinase 2, biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Aryl, Organic Chemistry, Haplorhini, Neoplasms, Experimental, Janus Kinase 2, Xenograft Model Antitumor Assays, Rats, Pyrimidines, biology.protein, Molecular Medicine
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المؤلفون: Hongyan Yan, Vinod V. Panikkath, Tony Chang, John Woolfrey, Jose Cabanillas, Li Liu, Prasad S. Gudem, Kamal Sahota
المصدر: 2010 10th IEEE International Conference on Solid-State and Integrated Circuit Technology.
مصطلحات موضوعية: Radio receiver design, CMOS, Code division multiple access, Computer science, dBm, Electronic engineering, Linearity, Integrated circuit design, Noise figure, Noise (radio)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cacc16d7b80624b519ad333bc393c3d7
https://doi.org/10.1109/icsict.2010.5667302 -
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المؤلفون: Lane A. Clizbe, Anjali Pandey, Robert M. Scarborough, Athiwat Hutchaleelaha, Zhaozhong J. Jia, Gary Park, Erick A. Goldman, James Kanter, Lingyan Wang, Yanhong Wu, Ting Su, Gary Probst, Wenhao Li, Susan Edwards, Jingmei Fan, Paul W. Wong, Stanley J. Hollenbach, Uma Sinha, Wenrong Huang, Bauer Shawn M, Joseph L. Lambing, Ann E. Arfsten, Yonghong Song, Penglie Zhang, Bing-Yan Zhu, Bao Liang, John Woolfrey
المصدر: Bioorganicmedicinal chemistry letters. 19(8)
مصطلحات موضوعية: ERG1 Potassium Channel, medicine.drug_mechanism_of_action, Stereochemistry, Pyridines, Clinical Biochemistry, Factor Xa Inhibitor, hERG, Pharmaceutical Science, Administration, Oral, Biochemistry, Chemical synthesis, Cell Line, Amidine, chemistry.chemical_compound, Dogs, In vivo, Catalytic Domain, Drug Discovery, medicine, Animals, Humans, Molecular Biology, biology, Dose-Response Relationship, Drug, Drug discovery, Chemistry, Organic Chemistry, Anticoagulants, Ether-A-Go-Go Potassium Channels, Rats, Macaca fascicularis, Enzyme inhibitor, Betrixaban, Benzamides, Factor Xa, biology.protein, Molecular Medicine, Rabbits, Factor Xa Inhibitors
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المؤلفون: Jing Ping Yang, Torsten Trowe, Roel Funke, Peter Lamb, Ryan Fong, David J. Matthews, Sotiria Boukouvala, Timothy S. Heuer, Yong D. Kim, Keith Calkins, Richard E. Cutler, John Woolfrey, Valentina Vysotskaia, Nicole Miller, Steven Brian Gendreau, Mary E. Gerritsen
المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research. 14(8)
مصطلحات موضوعية: Cancer Research, medicine.drug_class, Cell Survival, Protein Conformation, Receptor, ErbB-2, Antineoplastic Agents, Drug resistance, medicine.disease_cause, Lapatinib, Tyrosine-kinase inhibitor, medicine, Humans, Neoplastic transformation, Epidermal growth factor receptor, Phosphorylation, skin and connective tissue diseases, Protein Kinase Inhibitors, Mutation, ABL, biology, Kinase, Cell Transformation, Neoplastic, Oncology, Biochemistry, Drug Resistance, Neoplasm, Cancer research, biology.protein, Quinazolines, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968484d89e2590d2b3b31c09aa6308b5
https://pubmed.ncbi.nlm.nih.gov/18413839 -
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المؤلفون: Uma Sinha, Penglie Zhang, Erick A. Goldman, John Woolfrey, Yanhong Wu, Ting Su, Jingmei Zuckett, Bauer Shawn M, Lane A. Clizbe, Wenhao Li, Athiwat Hutchaleelaha, Stanley J. Hollenbach, Wenrong Huang, Zhaozhong J. Jia, Robert M. Scarborough, Joseph L. Lambing, Ann E. Arfsten, Yonghong Song, Bing-Yan Zhu
المصدر: Bioorganicmedicinal chemistry letters. 14(9)
مصطلحات موضوعية: Serine Proteinase Inhibitors, medicine.drug_mechanism_of_action, Stereochemistry, Clinical Biochemistry, Factor Xa Inhibitor, Pharmaceutical Science, Biological Availability, Biochemistry, Chemical synthesis, Amidine, chemistry.chemical_compound, Drug Discovery, medicine, Thiophene, Molecular Biology, biology, Organic Chemistry, Biological activity, Benzamidines, Piperazine, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Factor Xa Inhibitors
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