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1
المؤلفون: Jon L. Wright, et al. et al.
المصدر: ChemInform. 31
مصطلحات موضوعية: Stereochemistry, Chemistry, NMDA receptor, General Medicine, Subtype selective
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2
المؤلفون: Leonard T. Meltzer, Sham S. Nikam, Jon L. Wright, Julie McCormick, Kevin A. Serpa, Brian Edward Kornberg, Bridget M. Barr, Suzanne Ross Kesten, Linda L. Coughenour
المصدر: ChemInform. 35
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Biochemistry, Chemical synthesis, Receptors, N-Methyl-D-Aspartate, Drug Discovery, Animals, Structure–activity relationship, Receptor, Structural motif, Molecular Biology, IC50, Bicyclic molecule, Chemistry, Organic Chemistry, Antagonist, Brain, General Medicine, Subtype selective, In vitro, Rats, Alkynes, Molecular Medicine, NMDA receptor, Excitatory Amino Acid Antagonists, Linker
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3
المؤلفون: Jon L. Wright, et al. et al.
المصدر: ChemInform. 32
مصطلحات موضوعية: Chemistry, Stereochemistry, General Medicine, N-methyl-D-aspartate Receptor Antagonists, Subtype selective, Biological evaluation
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4
المؤلفون: Jon L. Wright, Tracy F. Gregory, Suzanne R. Kesten, Peter A. Boxer, Kevin A. Serpa, Leonard T. Meltzer, Lawrence D. Wise, Stephen A. Espitia, Christopher S. Konkoy, Edward R. Whittemore, Richard M. Woodward
المصدر: Journal of medicinal chemistry. 43(18)
مصطلحات موضوعية: Cerebral Cortex, Male, Patch-Clamp Techniques, Receptors, Dopamine D2, Administration, Oral, In Vitro Techniques, Transfection, Receptors, N-Methyl-D-Aspartate, Corpus Striatum, Rats, Antiparkinson Agents, Rats, Sprague-Dawley, Radioligand Assay, Xenopus laevis, Piperidines, Receptors, Adrenergic, alpha-1, Drug Discovery, Oocytes, Molecular Medicine, Animals, Benzimidazoles, Excitatory Amino Acid Antagonists
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5
المؤلفون: Sui Xiong Cai, Christina T. Shipp, Zhang-Lin Zhou, Jon L. Wright, John F. W. Keana, Manuel Acosta-Burruel, Suzanne R. Kesten, Minhtam Tran, Edward R. Whittemore, Jon E. Hawkinson, Amir P. Tamiz, Anthony P. Guzikowski, Richard M. Woodward, Soo Hong-Bae
المصدر: Journal of medicinal chemistry. 43(5)
مصطلحات موضوعية: Male, Pyrrolidines, Stereochemistry, Substituent, In Vitro Techniques, Chemical synthesis, Receptors, N-Methyl-D-Aspartate, Pyrrolidine, Receptors, Dopamine, Rats, Sprague-Dawley, chemistry.chemical_compound, Mice, Radioligand Assay, Xenopus laevis, Piperidines, Seizures, Receptors, Adrenergic, alpha-1, Drug Discovery, Ifenprodil, Phenyl group, Animals, Receptor, Cerebral Cortex, Electroshock, Corpus Striatum, Rats, chemistry, Oocytes, Molecular Medicine, NMDA receptor, Anticonvulsants, Piperidine, Excitatory Amino Acid Antagonists
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6
المؤلفون: Jon L. Wright, Tracy F. Gregory, Christopher F. Bigge, Peter A. Boxer, Kevin Serpa, Leonard T. Meltzer, Lawrence D. Wise, Sui Xiong Cai, Jon E. Hawkinson, Christopher S. Konkoy, Edward R. Whittemore, Richard M. Woodward, Zhang-Lin Zhou
المصدر: Journal of medicinal chemistry. 42(13)
مصطلحات موضوعية: Male, Stereochemistry, Propynyl, In Vitro Techniques, Chemical synthesis, Receptors, N-Methyl-D-Aspartate, Antiparkinson Agents, Levodopa, Rats, Sprague-Dawley, chemistry.chemical_compound, Radioligand Assay, Structure-Activity Relationship, Xenopus laevis, Phenols, Piperidines, Receptors, Adrenergic, alpha-1, Drug Discovery, Ifenprodil, Potency, Phenyl group, Animals, Oxidopamine, Receptors, Dopamine D2, Drug Synergism, Rats, Electrophysiology, chemistry, Benzyl group, Oocytes, Molecular Medicine, Piperidine, Excitatory Amino Acid Antagonists, Acetamide
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7
المؤلفون: Bharat Lagu, Thomas A Pugsley, Jon L Wright, Sham Shridhar Nikam, Hyacinth Akunne, Wise Lawrence David, Michael Konkel, Kim Zoski, Stewart A. Noble, Gamini Chandrasena, Lakmal W. Boteju, Tracy Gregory, Thomas P. Blackburn, Hermogenes N. Jimenez, Mary W. Walker, Brian E Kornberg
المصدر: Journal of Medicinal Chemistry. 49:3757-3758
مصطلحات موضوعية: Indoles, Stereochemistry, Ligands, Binding, Competitive, Chemical synthesis, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Chlorocebus aethiops, Drug Discovery, Cyclic AMP, Animals, Humans, Structure–activity relationship, heterocyclic compounds, Galanin, Receptor, Trifluoromethyl, Bicyclic molecule, Chemistry, Antagonist, Brain, Receptor, Galanin, Type 3, Stereoisomerism, Receptor, Galanin, Type 1, Rats, Receptor, Galanin, Type 2, COS Cells, Molecular Medicine, Imines
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8
المؤلفون: Roger N. Hayes, M. Rose Feng, Jon L. Wright, Dennis Michael Downing, T. A. Pugsley, Leonard T. Meltzer, Thomas G. Heffner, Lawrence D. Wise, Robert G. MacKenzie
المصدر: Journal of medicinal chemistry. 38(26)
مصطلحات موضوعية: Agonist, Magnetic Resonance Spectroscopy, medicine.drug_class, Stereochemistry, Metabolite, Dopamine, CHO Cells, Pharmacology, Motor Activity, Hydroxylation, Chemical synthesis, Mass Spectrometry, Receptors, Dopamine, chemistry.chemical_compound, Mice, Antipsychotic Agent, Dopamine receptor D3, Cricetinae, Drug Discovery, medicine, Avoidance Learning, Animals, Humans, Saimiri, Chromatography, High Pressure Liquid, Autoreceptors, Chemistry, Brain, Biological activity, Rats, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Dopamine Agonists, Autoreceptor, Molecular Medicine, medicine.drug, Antipsychotic Agents