المؤلفون: Rob S. Sellar, Adam S. Sperling, Mikołaj Słabicki, Jessica A. Gasser, Marie E. McConkey, Katherine A. Donovan, Nada Mageed, Dylan N. Adams, Charles Zou, Peter G. Miller, Ravi K. Dutta, Steffen Boettcher, Amy E. Lin, Brittany Sandoval, Vanessa A. Quevedo Barrios, Veronica Kovalcik, Jonas Koeppel, Elizabeth K. Henderson, Emma C. Fink, Lu Yang, Anthony Chan, Sheela Pangeni Pokharel, Erik J. Bergstrom, Rajan Burt, Namrata D. Udeshi, Steven A. Carr, Eric S. Fischer, Chun-Wei Chen, Benjamin L. Ebert

المصدر: The Journal of Clinical Investigation, Vol 132, Iss 16 (2022)

مصطلحات موضوعية: Hematology, Therapeutics, Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1558-8238

URL الوصول: https://doaj.org/article/81fae13f3404407c97508eb3a6337c9d

المؤلفون: Philip H. Jones, Moritz Gerstung, Benjamin A. Hall, Kourosh Saeb-Parsy, Krishnaa Mahububani, Amit Roshan, Doreen Milne, Edward Rytina, Kate Fife, Amer Durrani, David Shorthouse, Stefan C. Dentro, Jonas Koeppel, David Fernandez-Antoran, Eleanor Earp, Swee Hoe Ong, Roshan Sood, Michael W.J. Hall, Christopher Bryant, Charlotte King, Joanna C. Fowler

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da2713af077ae5bc61eaf6263b393c1
https://doi.org/10.1158/2159-8290.22536427

المؤلفون: Philip H. Jones, Moritz Gerstung, Benjamin A. Hall, Kourosh Saeb-Parsy, Krishnaa Mahububani, Amit Roshan, Doreen Milne, Edward Rytina, Kate Fife, Amer Durrani, David Shorthouse, Stefan C. Dentro, Jonas Koeppel, David Fernandez-Antoran, Eleanor Earp, Swee Hoe Ong, Roshan Sood, Michael W.J. Hall, Christopher Bryant, Charlotte King, Joanna C. Fowler

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::92b0c0c529c6f7cf94e8235bbfd78975
https://doi.org/10.1158/2159-8290.c.6548143.v1

المؤلفون: Jonas Koeppel, Juliane Weller, Elin Madli Peets, Ananth Pallaseni, Ivan Kuzmin, Uku Raudvere, Hedi Peterson, Fabio Giuseppe Liberante, Leopold Parts

المصدر: Nature Biotechnology.

مصطلحات موضوعية: Biomedical Engineering, Molecular Medicine, Bioengineering, Applied Microbiology and Biotechnology, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c713398ca7bcb093a7bd3ecbfe465931
https://doi.org/10.1038/s41587-023-01678-y

المؤلفون: Ananth Pallaseni, Elin Madli Peets, Jonas Koeppel, Juliane Weller, Thomas Vanderstichele, Uyen Linh Ho, Luca Crepaldi, Jolanda van Leeuwen, Felicity Allen, Leopold Parts

المصدر: Nucleic acids research, vol. 50, no. 6, pp. 3551-3564

مصطلحات موضوعية: Gene Editing, Cytosine, Adenine, CRISPR-Cas Systems, Cytosine/metabolism, Humans, Nucleotides, Genetics

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448acd85457e7d5eddf6c599dc15c9f5
https://doi.org/10.1093/nar/gkac161

المؤلفون: Charlotte King, Joanna C. Fowler, Jonas Koeppel, Kourosh Saeb-Parsy, Swee Hoe Ong, Moritz Gerstung, Benjamin A. Hall, Eleanor Earp, Amer Durrani, Krishnaa Mahububani, Kate Fife, David Shorthouse, Stefan C. Dentro, Christopher J. Bryant, Sood R, Michael W. J. Hall, Philip H. Jones, Amit Roshan, Edward Rytina, Doreen Milne, David Fernandez-Antoran

المساهمون: Shorthouse, David [0000-0002-3207-3584], Roshan, Amit [0000-0002-2034-2759], Saeb-Parsy, Kourosh [0000-0002-0633-3696], Hall, Benjamin [0000-0003-0355-2946], Jones, Philip [0000-0002-5904-795X], Apollo - University of Cambridge Repository

المصدر: Cancer Discovery. 11:340-361

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Skin Neoplasms, Mutant, Human skin, Biology, 03 medical and health sciences, 0302 clinical medicine, medicine, Ultraviolet light, Humans, Receptor, Notch1, Gene, Aged, Leg, integumentary system, Cancer, Middle Aged, Thorax, Cadherins, medicine.disease, Molecular biology, Clone Cells, Forearm, 030104 developmental biology, medicine.anatomical_structure, Oncology, Carcinoma, Basal Cell, 030220 oncology & carcinogenesis, Mutation, Carcinoma, Squamous Cell, Female, Skin cancer, Keratinocyte, FAT1

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f73fbf1e41c2f2896010a76b8b12e70
https://doi.org/10.1158/2159-8290.cd-20-1092

المؤلفون: Shourya S. Roy Burman, Rohan Sharma, Moritz Hunkeler, Peter Miller, Benjamin L. Ebert, Stefan Fröhling, Andrew A Guirguis, Claudia Scholl, Lena Nitsch, Priya Chudasama, Radosław P. Nowak, Hojong Yoon, Katherine A. Donovan, Cristina Di Genua, Charles Zou, Adam S. Sperling, Jessica A. Gasser, Eric S. Fischer, Jonathan M. Tsai, Mikolaj Slabicki, Jonas Koeppel

المصدر: Nature

مصطلحات موضوعية: 0301 basic medicine, Multidisciplinary, biology, 010405 organic chemistry, Chemistry, Biological activity, SIAH1, Protein degradation, 01 natural sciences, Small molecule, 0104 chemical sciences, 3. Good health, Cell biology, Ubiquitin ligase, 03 medical and health sciences, 030104 developmental biology, Ubiquitin, immune system diseases, hemic and lymphatic diseases, biology.protein, Target protein, Transcription factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593ed3b388c12a2bea67b34032dc473b
https://doi.org/10.1038/s41586-020-2925-1

المؤلفون: Ananth Pallaseni, Fabio Giuseppe Liberante, Elin Madli Peets, Jonas Koeppel, Leopold Parts, Juliane Weller

مصطلحات موضوعية: Sequence, Computer science, DNA mismatch repair, Computational biology, Insertion sequence, Human cell, Genome, Nucleotide composition, Prime (order theory), Insert (molecular biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::89034d65ff747e099f5b079f1314765a
https://doi.org/10.1101/2021.11.10.468024

المؤلفون: Dennis Gillingham, Jessica A. Gasser, Rob S. Sellar, Eric S. Fischer, Max Jan, Todd R. Golub, Manisha Manojkumar, Nicolas H. Thomä, Quinlan L. Sievers, Claudia Scholl, Stefan Fröhling, Li R. Wang, Zuzanna Kozicka, Katherine A. Donovan, Emma C. Fink, Adam S. Sperling, Yen-Der Li, Steven M. Corsello, Mikolaj Slabicki, Richard D. Bunker, Georg Petzold, Benjamin L. Ebert, Dakota Suchyta, Jonas Koeppel

المصدر: Nature

مصطلحات موضوعية: Models, Molecular, Proteasome Endopeptidase Complex, Pyridines, CDK, Context (language use), 01 natural sciences, Article, Small Molecule Libraries, 03 medical and health sciences, DDB1, Ubiquitin, Cyclin-dependent kinase, Cell Line, Tumor, Cyclins, ubiquitin, Humans, 030304 developmental biology, 0303 health sciences, Multidisciplinary, biology, 010405 organic chemistry, Chemistry, Ubiquitination, ligase, molecular glue degrader, Signal transducing adaptor protein, Small molecule, Cyclin-Dependent Kinases, 3. Good health, 0104 chemical sciences, Cell biology, Ubiquitin ligase, DNA-Binding Proteins, inhibitor, Purines, Proteolysis, biology.protein, CDK inhibitor, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f945e27008c0da8a9d7dd121f5cde3
https://doi.org/10.1038/s41586-020-2374-x

المؤلفون: Mikołaj Słabicki, Hojong Yoon, Jonas Koeppel, Lena Nitsch, Shourya S. Roy Burman, Cristina Genua, Katherine A. Donovan, Adam S. Sperling, Moritz Hunkeler, Jonathan M. Tsai, Rohan Sharma, An

المصدر: Nature, Nature. 588(7836):164-168

الإتاحة: https://ideas.repec.org/a/nat/nature/v588y2020i7836d10.1038_s41586-020-2925-1.html