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1
المؤلفون: Charles M. Langevine, Joseph A. Furch, Dominique Belanger, Mark A. Pattoli, Joel C. Barrish, Alaric J. Dyckman, Marco Dodier, James Kempson, Jagabandhu Das, David S. Nirschl, Laishun Chen, Punit Marathe, Kathleen M. Gillooly, Junqing Guo, Robert V. Moquin, John H. Dodd, Murray McKinnon, Anne Marinier, Zheng Yang, Steven H. Spergel, Claude A. Quesnelle, Kim W. McIntyre, Katy Van Kirk, James R. Burke, William J. Pitts, Scott H. Watterson, Alain Martel, Patrice Gill, David B. Wang-Iverson, Tianle Li
المصدر: Journal of Medicinal Chemistry. 52:1994-2005
مصطلحات موضوعية: Lipopolysaccharides, Recombinant Fusion Proteins, IκB kinase, In Vitro Techniques, Crystallography, X-Ray, Chemical synthesis, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Animals, Humans, Thiazole, Oxazoles, Glutathione Transferase, Oxazole, chemistry.chemical_classification, Mice, Inbred BALB C, Tumor Necrosis Factor-alpha, Imidazoles, Biological activity, I-kappa B Kinase, Rats, Thiazoles, Enzyme, chemistry, Biochemistry, Leukocytes, Mononuclear, Microsomes, Liver, Molecular Medicine, Female, Signal transduction, Heterocyclic Compounds, 3-Ring, Tricyclic
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2
المؤلفون: Mary T. Obermeier, Mark E. Salvati, Michael Galella, Jack Z. Gougoutas, Ricardo M. Attar, Giese Soren, Stanley R. Krystek, Aaron Balog, Maria Jure-Kunkel, Gamini Chandrasena, Marco M. Gottardis, Weifang Shan, Jieping Geng, Aberra Fura, Joseph A. Furch, Cheryl A. Rizzo, Tom Mitt, Gregory D. Vite, Richard Rampulla
المصدر: Bioorganic & Medicinal Chemistry Letters. 18:1910-1915
مصطلحات موضوعية: Male, Models, Molecular, Bicalutamide, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Isoindoles, Pharmacology, Antiandrogen, Biochemistry, Tosyl Compounds, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Prostate cancer, In vivo, Nitriles, Drug Discovery, Androgen Receptor Antagonists, Tumor Cells, Cultured, medicine, Animals, Humans, Anilides, Imide, Molecular Biology, Chromatography, High Pressure Liquid, Mice, Inbred BALB C, Molecular Structure, Organic Chemistry, Prostatic Neoplasms, Androgen Antagonists, Bridged Bicyclo Compounds, Heterocyclic, medicine.disease, Androgen receptor, chemistry, Receptors, Androgen, Drug Design, Molecular Medicine, Lead compound, Protein Binding, medicine.drug
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3
المؤلفون: Joel C. Barrish, David J. Shuster, Chunjian Liu, Kim W. McIntyre, Tai-An Lin, Amrita Kamath, Becky Penhallow, Kathleen D. O'Day, Steven B. Kanner, Joseph A. Furch, John H. Dodd, Steven H. Spergel, Hongjian Zhang, James Lin, Robert V. Moquin, Arthur M. Doweyko, John Wityak, Punit Marathe, Jagabandhu Das, Chen Yi Hung
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:3706-3712
مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Sulfides, Biochemistry, Jurkat cells, Jurkat Cells, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Aminothiazole, In vivo, Drug Discovery, Hypersensitivity, Animals, Humans, Enzyme Inhibitors, Molecular Biology, Cells, Cultured, chemistry.chemical_classification, biology, Organic Chemistry, Pneumonia, Protein-Tyrosine Kinases, Small molecule, Asthma, In vitro, Thiazoles, Ovalbumin, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine
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4
المؤلفون: Joseph Augustus Furch, Robert Eugene Diehl, Kuhn David G, Victor Marc Kamhi, Venkataraman Kameswaran, Gregory Thomas Lowen
المصدر: Pesticide Science. 41:279-286
مصطلحات موضوعية: Stereochemistry, Structural isomer, Regioselectivity, Biological activity, Biology, Applied Microbiology and Biotechnology, Chemical synthesis, Pyrrole derivatives
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المؤلفون: Victor Marc Kamhi, Kuhn David G, Trotto Susan, Joseph Augustus Furch, R. M. Peevey, Venkataraman Kameswaran, M. F. Treacy, R. W. Addor, T. P. Miller, J. B. Lovell, T. J. Babcock, Gregory Thomas Lowen, Bruce Christian Black, D. P. Jun. Wright, Robert Eugene Diehl, Brown Dale Gordon, Jack K. Siddens, Kremer Kenneth Alfred Martin
المصدر: ChemInform. 24
مصطلحات موضوعية: Chemistry, Organic chemistry, General Medicine, Pyrrole derivatives
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6
المؤلفون: Joel C. Barrish, T. G. Murali Dhar, Arthur M. Doweyko, Shuqun Lin, Sidney Pitt, Arvind Mathur, Yi Fan, John H. Dodd, Murray McKinnon, Katerina Leftheris, John S. Sack, Gary L. Schieven, Stephen T. Wrobleski, Gordon Todderud, Joseph A. Furch, David S. Nirschl
المصدر: Bioorganicmedicinal chemistry letters. 17(18)
مصطلحات موضوعية: Models, Molecular, Molecular model, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Crystallography, X-Ray, Biochemistry, Chemical synthesis, p38 Mitogen-Activated Protein Kinases, Bridged Bicyclo Compounds, Structure-Activity Relationship, Heterocyclic Compounds, Drug Discovery, Pyrazolopyridine, medicine, Transferase, Molecular Biology, Protein Kinase Inhibitors, chemistry.chemical_classification, biology, Organic Chemistry, Enzyme, chemistry, Enzyme inhibitor, Mitogen-activated protein kinase, biology.protein, Molecular Medicine
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7
المؤلفون: Jagabandhu, Das, Chunjian, Liu, Robert V, Moquin, James, Lin, Joseph A, Furch, Steven H, Spergel, Arthur M, Doweyko, Kim W, McIntyre, David J, Shuster, Kathleen D, O'Day, Becky, Penhallow, Chen-Yi, Hung, Steven B, Kanner, Tai-An, Lin, John H, Dodd, Joel C, Barrish, John, Wityak
المصدر: Bioorganicmedicinal chemistry letters. 16(9)
مصطلحات موضوعية: Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Clinical Biochemistry, Receptors, Antigen, T-Cell, Pharmaceutical Science, Antibodies, Monoclonal, Protein-Tyrosine Kinases, Biochemistry, Jurkat Cells, Mice, Structure-Activity Relationship, Thiazoles, Drug Discovery, Molecular Medicine, Animals, Humans, Interleukin-2, Enzyme Inhibitors, Molecular Biology
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8
المؤلفون: Steven B. Kanner, Steven H. Spergel, Kim W. McIntyre, Robert M. Townsend, Gena S. Whitney, Robert V. Moquin, David J. Shuster, Joel C. Barrish, Juan J. Perez-Villar, Chunjian Liu, Amrita Kamath, Loran Killar, John H. Dodd, Jagabandhu Das, Xiao Xia Yang, John Wityak, Chen Yi Hung, Jennifer Postelnek, Tai-An Lin, Kathleen D. O'Day, Joseph A. Furch, Hongjian Zhang, Punit Marathe, Becky Penhallow, Arthur M. Doweyko, James Lin
المصدر: Biochemistry. 43(34)
مصطلحات موضوعية: T cell, T-Lymphocytes, Receptors, Antigen, T-Cell, Biology, Lymphocyte Activation, Biochemistry, Jurkat cells, chemistry.chemical_compound, Jurkat Cells, Mice, Cell Line, Tumor, medicine, Respiratory Hypersensitivity, Animals, Humans, Kinase activity, Enzyme Inhibitors, Receptor, Lung, Gene knockout, Mice, Inbred BALB C, Kinase, T-cell receptor, Anti-Inflammatory Agents, Non-Steroidal, Tyrosine phosphorylation, Protein-Tyrosine Kinases, medicine.anatomical_structure, chemistry, Cancer research, Interleukin-2, Immunosuppressive Agents
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9
المؤلفون: Robert Eugene Diehl, S. P. Baffic, Kuhn David G, Y. L. Palmer, Joseph Augustus Furch, Trotto Susan, David A. Hunt, M. Asselin
المصدر: ACS Symposium Series ISBN: 9780841235465
Synthesis and Chemistry of Agrochemicals Vمصطلحات موضوعية: New class, Chemistry, Stereochemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::327e5ac0b959370bccbf116ca6bdd08c
https://doi.org/10.1021/bk-1998-0686.ch018 -
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المؤلفون: M. F. Treacy, Kuhn David G, Y. L. Palmer, Robert Eugene Diehl, M. Asselin, Trotto Susan, S. P. Baffic, David A. Hunt, T. P. Miller, Joseph Augustus Furch
المصدر: ACS Symposium Series ISBN: 9780841235465
Synthesis and Chemistry of Agrochemicals Vمصطلحات موضوعية: Class (computer programming), Chemistry, Stereochemistry, media_common.quotation_subject, Insect, Control (linguistics), media_common
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c19c9a74f2d1d2c3bc96c2fcc8640a38
https://doi.org/10.1021/bk-1998-0686.ch019