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المؤلفون: Angelina R. Sekirnik, Jessica K. Reynolds, Larissa See, Joseph P. Bluck, Amy R. Scorah, Cynthia Tallant, Bernadette Lee, Katarzyna B. Leszczynska, Rachel L. Grimley, R. Ian Storer, Marta Malattia, Sara Crespillo, Sofia Caria, Stephanie Duclos, Ester M. Hammond, Stefan Knapp, Garrett M. Morris, Fernanda Duarte, Philip C. Biggin, Stuart J. Conway
المصدر: ACS Chemical Biology. 17:2753-2768
مصطلحات موضوعية: Histones, DNA-Binding Proteins, Peptide T, Lysine, Ubiquitin-Protein Ligases, Nuclear Proteins, Molecular Medicine, General Medicine, Ligands, Ubiquitins, Biochemistry, Transcription Factors
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المؤلفون: Douglas L. Orsi, Steven J. Ferrara, Stephan Siegel, Anders Friberg, Léa Bouché, Elisabeth Pook, Philip Lienau, Joseph P. Bluck, Christopher T. Lemke, Gizem Akcay, Timo Stellfeld, Hanna Meyer, Vera Pütter, Simon J. Holton, Daniel Korr, Isabel Jerchel-Furau, Constantia Pantelidou, Craig A. Strathdee, Matthew Meyerson, Knut Eis, Jonathan T. Goldstein
المصدر: Bioorganic & medicinal chemistry 78, 117130 (2023). doi:10.1016/j.bmc.2022.117130
مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, ddc:610, Molecular Biology, Biochemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8a065063af626237bd6ead93ee15d7
https://bib-pubdb1.desy.de/record/491342 -
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المؤلفون: Marko Breznik, Yunhui Ge, Joseph P. Bluck, Hans Briem, David F. Hahn, Clara D. Christ, Jérémie Mortier, David L. Mobley, Katharina Meier
المصدر: ChemMedChem. 18
مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry
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المؤلفون: Katharina Meier, Joseph P. Bluck, Clara D. Christ
المصدر: Free Energy Methods in Drug Discovery: Current State and Future Directions ISBN: 9780841298064
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f3ef9c01b6eb9deef3a0c2d728901906
https://doi.org/10.1021/bk-2021-1397.ch002 -
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المؤلفون: Matthias Schiedel, Katrina H. Andrews, Corentine M.C. Laurin, Joseph P. Bluck, Stuart J. Conway, Prakriti Kalra, Panagis Filippakopoulos, James Clayton, Anthony K. N. Chan, Amy R. Scorah, Oleg Fedorov, Ester M. Hammond, Mustafa Moroglu, Kayla B. Vinh, William C. K. Pomerantz, Richard I. Cooper, Wilian A. Cortopassi, Pascal Heitel, Robert S. Paton, Anna Skwarska, Gabriella T. Perell, Kirsten E. Christensen, Larissa See, Hannah Bolland, Timothy P. C. Rooney, Sarah Picaud, Philip C. Biggin, Michael Brand
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: BRD4, Lysine Acetyltransferases, Lysine, Ligands, 01 natural sciences, Interactome, Article, Small Molecule Libraries, 03 medical and health sciences, Structure-Activity Relationship, Drug Discovery, Structure–activity relationship, Humans, 030304 developmental biology, 0303 health sciences, Benzodiazepinones, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, HCT116 Cells, CREB-Binding Protein, 0104 chemical sciences, Cell biology, Bromodomain, Histone, Acetylation, Drug Design, biology.protein, Molecular Medicine, E1A-Associated p300 Protein
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المؤلفون: Corentine M C, Laurin, Joseph P, Bluck, Anthony K N, Chan, Michelle, Keller, Andrew, Boczek, Amy R, Scorah, K F Larissa, See, Laura E, Jennings, David S, Hewings, Fern, Woodhouse, Jessica K, Reynolds, Matthias, Schiedel, Philip G, Humphreys, Philip C, Biggin, Stuart J, Conway
المصدر: ACS infectious diseases. 7(8)
مصطلحات موضوعية: Trypanosoma cruzi, Escherichia coli, Humans, Chagas Disease, Ligands, Epigenesis, Genetic
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المؤلفون: Ishna N. Mistry, Philip G. Humphreys, Panagis Filippakopoulos, Amy Hicks, Pavel Guzanov, Laura E. Jennings, Larissa See, Jessica K. Reynolds, Amy R. Scorah, Matthias Schiedel, Anna K. Mapp, James Clayton, David S. Hewings, Paul A. Bruno, Mustafa Moroglu, Charles N. G. Evans, Corentine M.C. Laurin, Stuart J. Conway, Joseph P. Bluck, Ester M. Hammond, Giulia Stazi, Sarah Picaud, Philip C. Biggin
المصدر: Bioorganic & Medicinal Chemistry
مصطلحات موضوعية: 0301 basic medicine, BRD4, Protein subunit, Blotting, Western, Clinical Biochemistry, Pharmaceutical Science, Cell Cycle Proteins, Molecular Dynamics Simulation, Crystallography, X-Ray, Ligands, Heterocyclic Compounds, 4 or More Rings, Biochemistry, Histone H4, Inhibitory Concentration 50, Structure-Activity Relationship, 03 medical and health sciences, Drug Stability, Drug Discovery, Humans, Structure–activity relationship, Molecule, Luciferases, Molecular Biology, Molecular Structure, Chemistry, Ligand, Hydrogen bond, Organic Chemistry, Nuclear Proteins, Combinatorial chemistry, 3. Good health, Bromodomain, 030104 developmental biology, MCF-7 Cells, Molecular Medicine, Biological Assay, Transcription Factors
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8كتاب إلكتروني
المؤلفون: Kira A. Armacost, David C. Thompson, Zoe Cournia, Christophe Chipot, Benoît Roux, Darrin M. York, Woody Sherman, Katharina Meier, Joseph P. Bluck, Clara D. Christ, Nicolas Tielker, Lukas Eberlein, Oliver Beckstein, Stefan Güssregen, Bogdan I. Iorga, Stefan M. Kast, Shuai Liu, Miroslav Suruzhon, Marley L. Samways, Jonathan W. Essex, Ayşegül Özen, Emanuele Perola, Natasja Brooijmans, Joseph Kim, Dilek Coskun, Tai-Sung Lee, Hsu-Chun Tsai, Abir Ganguly, Timothy J. Giese, Jennifer L. Knight, Karl Leswing, Pieter H. Bos, Lingle Wang, Paul Labute, Maximilian Ebert, Lance M. Westerhoff, Zheng Zheng, Eric C. Gladstone
نوع المادة: eBook.
الموضوعات: Thermodynamic potentials, Drugs--Design, Drug development
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المؤلفون: Philip C. Biggin, Matteo Aldeghi, Joseph P. Bluck
المصدر: Methods in Molecular Biology ISBN: 9781493977550
مصطلحات موضوعية: Models, Molecular, Molecular model, Molecular Dynamics Simulation, 010402 general chemistry, Ligands, 01 natural sciences, Organic molecules, Small Molecule Libraries, Molecular dynamics, 0103 physical sciences, Molecule, Physics, Binding Sites, 010304 chemical physics, Computational Biology, Proteins, Statistical mechanics, Small molecule, 0104 chemical sciences, Molecular Docking Simulation, Chemical physics, Thermodynamics, Energy (signal processing), Software, Macromolecule, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e433db0a6a6541d6c16c9a6d93bfa787
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