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المؤلفون: Rishi Ramesh, Sutthilug Sotthivirat, Chad D. Brown, Binfeng Xia, Cory Bottone, Walter Wasylaschuk, Joyce Stellabott, Daniel Skomski, Michael J. McNevin
المصدر: Powder Technology. 375:302-309
مصطلحات موضوعية: H2 Receptor Blockers, General Chemical Engineering, 02 engineering and technology, Polyethylene glycol, 021001 nanoscience & nanotechnology, Bioavailability, chemistry.chemical_compound, Granulation, 020401 chemical engineering, Pulmonary surfactant, chemistry, Chemical engineering, Water soluble drug, 0204 chemical engineering, Solubility, 0210 nano-technology, Dissolution
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المؤلفون: Robert Wenslow, Yongchao Su, Freddy A Arce, Nico Setiawan, Alfred C. F. Rumondor, Justin Moser, Pavithra Sundararajan, Sadegh Poozesh, Shawn Zhang, Patrick J. Marsac, Hanmi Xi, Douglas Wei, Joyce Stellabott, Joseph Della Rocca
المصدر: Powder Technology. 320:685-695
مصطلحات موضوعية: Materials science, General Chemical Engineering, Analytical chemistry, 02 engineering and technology, 021001 nanoscience & nanotechnology, 030226 pharmacology & pharmacy, Characterization (materials science), Amorphous solid, 03 medical and health sciences, 0302 clinical medicine, Chemical engineering, Spray drying, Phase (matter), Particle, Particle size, 0210 nano-technology, Porosity, Dispersion (chemistry)
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المؤلفون: Kendra Galipeau, Dorothy Levorse, Paul L. Walsh, Filippos Kesisoglou, Joyce Stellabott, Wei Xu, Rebecca Nofsinger
المصدر: AAPS PharmSciTech. 18:1408-1416
مصطلحات موضوعية: Drug Compounding, Biological Availability, Pharmaceutical Science, 02 engineering and technology, Absorption (skin), Aquatic Science, Pharmacology, Risk Assessment, 030226 pharmacology & pharmacy, Beagle, Intestinal fluid, Dosage form, 03 medical and health sciences, Dogs, 0302 clinical medicine, Drug Discovery, Animals, Humans, Intestinal Mucosa, Solubility, Dissolution, Ecology, Evolution, Behavior and Systematics, Chromatography, Ecology, Chemistry, Fasting, General Medicine, 021001 nanoscience & nanotechnology, Bioavailability, Biopharmaceutical, 0210 nano-technology, Agronomy and Crop Science
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المؤلفون: John J. Renger, Joyce Stellabott, Swati P. Mercer, Wei Lemaire, Thomas S. Reger, Christopher D. Cox, Pamela L. Tannenbaum, Christopher J. Winrow, Joanne Stevens, Donghui Cui, Joseph G. Bruno, Susan L. Garson, Rowena V. Cube, M. Christa Mattern, Dansu Li, C. Meacham Harrell, Paul J. Coleman, John D. Schreier, Tamara D. Cabalu, George D. Hartman, Anthony L. Gotter, Steven V. Fox, Jeffrey M. Bergman, Anthony J. Roecker, Thomayant Prueksaritanont, Steven D. Young
المصدر: Bioorganic & Medicinal Chemistry Letters. 24:4884-4890
مصطلحات موضوعية: medicine.medical_specialty, Pyridines, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Doras, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Sleep Initiation and Maintenance Disorders, Internal medicine, mental disorders, Drug Discovery, medicine, Animals, Humans, Isonicotinamide, Receptor, Molecular Biology, Dose-Response Relationship, Drug, Molecular Structure, biology, CYP3A4, Organic Chemistry, Antagonist, biology.organism_classification, Small molecule, Orexin receptor, Rats, Orexin, Thiazoles, Endocrinology, chemistry, Molecular Medicine, Orexin Receptor Antagonists
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المؤلفون: Joyce Stellabott, Allen C. Templeton, Michael H. Kress, William Marinaro, Karen C. Thompson, Dan Zhang, Brett Duersch, Alfred C. F. Rumondor, Filippos Kesisoglou
المصدر: Discovering and Developing Molecules with Optimal Drug-Like Properties ISBN: 9781493913985
مصطلحات موضوعية: Active ingredient, Materials science, Telcagepant, food.ingredient, Excipient, Capsule, Nanotechnology, Gelatin, Dosage form, Clinical formulation, food, New chemical entity, medicine, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::42586be2313ab50cb7c254552f003784
https://doi.org/10.1007/978-1-4939-1399-2_14 -
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المؤلفون: Anthony J. Roecker, Tamara D. Cabalu, Mark E. Fraley, Thomayant Prueksaritanont, John J. Renger, Paul J. Coleman, Wei Lemaire, Pamela L. Tannenbaum, Joseph G. Bruno, Steven V. Fox, Susan L. Garson, Christopher D. Cox, Christopher J. Winrow, Anthony L. Gotter, Joyce Stellabott, John D. Schreier, Donghui Cui, George D. Hartman, Swati P. Mercer, Justin T. Steen, Joanne Stevens, Steven D. Young, C. Meacham Harrell
المصدر: ChemMedChem. 9(2)
مصطلحات موضوعية: Male, medicine.drug_class, Pyridines, Carboxamide, Pharmacology, Biochemistry, Rats, Sprague-Dawley, Mice, Dogs, In vivo, Sleep Initiation and Maintenance Disorders, Drug Discovery, medicine, Animals, Humans, General Pharmacology, Toxicology and Pharmaceutics, Receptor, Orexins, Chemistry, Organic Chemistry, Suvorexant, Neuropeptides, Antagonist, Intracellular Signaling Peptides and Proteins, Macaca mulatta, Orexin receptor, Orexin, Rats, Mice, Inbred C57BL, Drug Design, Molecular Medicine, Orexin antagonist
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المؤلفون: Thomayant Prueksaritanont, Anthony L. Gotter, Duane R. Reiss, Michael J. Bogusky, Joanne Stevens, Christopher D. Cox, Tamara D. Cabalu, David B. Whitman, John D. Schreier, Joyce Stellabott, Georgia B. McGaughey, Michael J. Breslin, Rodney A. Bednar, Christopher J. Winrow, Donghui Cui, Pamela L. Tannenbaum, Susan L. Garson, John J. Renger, Scott M. Doran, C. Meacham Harrell, Paul J. Coleman, Richard G. Ball, Steven D. Young, Wei Lemaire, George D. Hartman, Steven V. Fox
المصدر: ChemMedChem. 7(3)
مصطلحات موضوعية: Models, Molecular, Receptors, Neuropeptide, Filorexant, Magnetic Resonance Spectroscopy, medicine.drug_class, Pyridines, Carboxamide, Pharmacology, Doras, Biochemistry, Receptors, G-Protein-Coupled, Structure-Activity Relationship, Dogs, Piperidines, Orexin Receptors, Sleep Initiation and Maintenance Disorders, mental disorders, Drug Discovery, medicine, Animals, Humans, Hypnotics and Sedatives, General Pharmacology, Toxicology and Pharmaceutics, Wakefulness, biology, Chemistry, Organic Chemistry, Antagonist, Brain, Stereoisomerism, Triazoles, biology.organism_classification, Orexin receptor, Orexin, Rats, Molecular Medicine, Sleep onset, Sleep, GABA Modulators, medicine.drug, Protein Binding
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المؤلفون: Christopher D. Cox, Thomayant Prueksaritanont, Steven V. Fox, Anthony J. Roecker, John D. Schreier, Wei Lemaire, Joyce Stellabott, Joseph G. Bruno, Pamela L. Tannenbaum, Anthony L. Gotter, George D. Hartman, Paul J. Coleman, Susan L. Garson, Tamara D. Cabalu, Steven D. Young, John J. Renger, Mark E. Fraley, C. Meacham Harrell, Christopher J. Winrow, Donghui Cui, Justin T. Steen, Swati P. Mercer, Joanne Stevens
المصدر: ChemMedChem. 9:241-241
مصطلحات موضوعية: Pharmacology, medicine.drug_class, Organic Chemistry, Orexin hypocretin, Antagonist, Carboxamide, Biochemistry, Orexin receptor, chemistry.chemical_compound, chemistry, Drug Discovery, medicine, Molecular Medicine, Cover (algebra), General Pharmacology, Toxicology and Pharmaceutics, Terpyridine
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المؤلفون: Rodney A. Bednar, Christopher J. Winrow, Pamela L. Tannenbaum, Michael J. Bogusky, Anthony L. Gotter, David B. Whitman, Susan L. Garson, Wei Lemaire, Tamara D. Cabalu, Michael J. Breslin, Donghui Cui, Richard G. Ball, Thomayant Prueksaritanont, John D. Schreier, Steven V. Fox, George D. Hartman, C. Meacham Harrell, John J. Renger, Scott M. Doran, Christopher D. Cox, Duane R. Reiss, Steven D. Young, Joanne Stevens, Joyce Stellabott, Paul J. Coleman, Georgia B. McGaughey
المصدر: ChemMedChem. 7:337-337
مصطلحات موضوعية: Pharmacology, Chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Antagonist, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry, Orexin receptor
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