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المؤلفون: Angela Yen, Damiano Rondelli, la Fuente Josu de, Amanda M. Li, Jennifer Domm, Montalembert Mariane de, Tony W. Ho, Donna A. Wall, Brenda K. Eustace, Juergen Foell, Sujit Sheth, Haydar Frangoul, Rupert Handgretinger, Akshay Sharma, Sandeep Soni, Antonis Kattamis, Andrew Kernytsky, Franco Locatelli, Stephan A. Grupp, M. Domenica Cappellini, Julie A. Lekstrom-Himes, Selim Corbacioglu, David Altshuler, Markus Y. Mapara, Yi-Shan Chen, Martin H. Steinberg
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Anemia, Thalassemia, Cell, CD34, Disease, Biology, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Genome editing, hemic and lymphatic diseases, Fetal hemoglobin, medicine, CRISPR, 030212 general & internal medicine, Progenitor cell, Enhancer, Genetics, business.industry, Obstetrics and Gynecology, General Medicine, medicine.disease, Haematopoiesis, medicine.anatomical_structure, Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA, Immunology, Bone marrow, CRISPR-Cas9, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294f2984b8848005c8f160412c9178cd
https://hdl.handle.net/10807/228473 -
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المؤلفون: Mary Louise Morris, Julie A. Lekstrom-Himes, Arthur M. Krieg, Heather L. Davis, Philip Leese, Chantal Laframboise, Alain Vicari, Mohammed J Al-Adhami, Susan M. Efler, Tess Schmalbach
المصدر: Antiviral Therapy. 12:741-751
مصطلحات موضوعية: Pharmacology, Agonist, medicine.drug_class, medicine.medical_treatment, TLR9, Biology, Toll-Like Receptor 9, Infectious Diseases, Cytokine, Pharmacokinetics, CpG site, Immunology, Toxicity, medicine, Pharmacology (medical), Receptor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::361bf1720f203cb76d0327921c25bbf7
https://doi.org/10.1177/135965350701200501 -
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المؤلفون: Vincent Idone, Theresa Zibello, Arati Khanna-Gupta, Julie A. Lekstrom-Himes, Hong Sun, Nancy Berliner
المصدر: Experimental Hematology. 33:42-52
مصطلحات موضوعية: Cancer Research, Myeloid, Biology, Transfection, Cell Line, Mice, Downregulation and upregulation, CCAAT-Enhancer-Binding Protein-alpha, Genetics, medicine, Animals, Humans, Promoter Regions, Genetic, Molecular Biology, Gene, Transcription factor, Myelopoiesis, Binding Sites, Ccaat-enhancer-binding proteins, Oligonucleotide, Promoter, Cell Biology, Hematology, Molecular biology, Up-Regulation, Lactoferrin, Matrix Metalloproteinase 8, medicine.anatomical_structure, Gene Expression Regulation, CCAAT-Enhancer-Binding Proteins, Chromatin immunoprecipitation
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المؤلفون: Pu Zhang, Koichi Akashi, Hirokazu Shigematsu, Elena Levantini, Julie A. Lekstrom-Himes, Hiromi Iwasaki, Daniel G. Tenen, Junko Iwasaki-Arai, Bronwyn M. Owens, Tajhal Dayaram, Maris Fenyus, Claudia S. Huettner
المصدر: Immunity. 21:853-863
مصطلحات موضوعية: Aging, Myeloid, Cellular differentiation, Immunology, Biology, Mice, 03 medical and health sciences, Fetus, 0302 clinical medicine, hemic and lymphatic diseases, CCAAT-Enhancer-Binding Protein-alpha, medicine, Animals, Immunology and Allergy, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Myeloid leukemia, Hematopoietic stem cell, Cell Differentiation, Hematopoietic Stem Cells, medicine.disease, Blood Cell Count, Hematopoiesis, Haematopoiesis, Leukemia, Infectious Diseases, medicine.anatomical_structure, Liver, Leukemia, Myeloid, 030220 oncology & carcinogenesis, Cancer research, Bone marrow, Stem cell, Gene Deletion, Granulocytes
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المؤلفون: Monika J. Stankiewicz, Qing Xi, Jonathan E. Schmitz, Yang Liu, Julie A. Lekstrom-Himes, Steven J. Ackerman, Jian Du
المصدر: Journal of Biological Chemistry. 277:43481-43494
مصطلحات موضوعية: Gene isoform, Repressor, Blood Donors, Biology, Biochemistry, Ribonucleases, Transcription (biology), Proto-Oncogene Proteins, Consensus Sequence, Transcriptional regulation, medicine, Humans, Protein Isoforms, GATA1 Transcription Factor, Promoter Regions, Genetic, Molecular Biology, Gene, Sequence Deletion, Cell Nucleus, Leucine Zippers, Base Sequence, Ccaat-enhancer-binding proteins, Blood Proteins, Cell Biology, Eosinophil Granule Proteins, Molecular biology, DNA-Binding Proteins, Eosinophils, medicine.anatomical_structure, Gene Expression Regulation, Mutagenesis, CCAAT-Enhancer-Binding Proteins, Trans-Activators, Major basic protein, biology.protein, Erythroid-Specific DNA-Binding Factors, 5' Untranslated Regions, Myelocyte, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5d677759fb5a2ebcbe5fc86d4c0dbd
https://doi.org/10.1074/jbc.m204777200 -
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المصدر: Journal of Cellular Biochemistry. 80:606-616
مصطلحات موضوعية: Regulation of gene expression, Therapeutic gene modulation, Genetics, Gene product, S100A9 Gene, Gene cluster, Pair-rule gene, Gene targeting, Cell Biology, Biology, Molecular Biology, Biochemistry, Regulator gene
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d5203d75c5820ae9e0bbcffdd0f9af09
https://doi.org/10.1002/1097-4644(20010315)80:4<606::aid-jcb1015>3.0.co;2-k -
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المؤلفون: Julie A. Lekstrom-Himes, Matthew Godleski, Lesley Pesnicak, Sharon E. Straus, Rona A. LeBlanc
المصدر: Journal of Virology. 74:6680-6683
مصطلحات موضوعية: Ultraviolet Rays, viruses, medicine.medical_treatment, Immunology, Eye Infections, Viral, Herpesvirus 1, Human, Biology, medicine.disease_cause, Polymerase Chain Reaction, Microbiology, Virus, Interferon-gamma, Mice, Species Specificity, Virology, Chlorocebus aethiops, Virus latency, medicine, Animals, Interferon gamma, Vero Cells, Mice, Knockout, Mice, Inbred BALB C, Virus Activation, medicine.disease, Virus Latency, Mice, Inbred C57BL, Disease Models, Animal, Herpes simplex virus, Cytokine, Real-time polymerase chain reaction, Trigeminal Ganglion, Insect Science, Acute Disease, DNA, Viral, Vero cell, Pathogenesis and Immunity, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc92c2cdbd9d09dd7681796096dd13f
https://doi.org/10.1128/jvi.74.14.6680-6683.2000 -
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المؤلفون: David C. Dale, Mary C. Dinauer, Julie A. Lekstrom-Himes
المصدر: Hematology. 2000:303-318
مصطلحات موضوعية: Hematology, Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad23da56442c27c275342b5af4992cc
https://doi.org/10.1182/asheducation.v2000.1.303.20000303 -
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المؤلفون: David C. Dale, Julie A. Lekstrom-Himes, Mary C. Dinauer
المصدر: Hematology. 2000:303-318
مصطلحات موضوعية: medicine.medical_specialty, biology, Genetic enhancement, Gene targeting, Hematology, medicine.disease, Chronic granulomatous disease, Enhancer binding, Neutrophil elastase, Molecular genetics, Immunology, Knockout mouse, medicine, biology.protein, Congenital Neutropenia
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcba5fb09233138d31c58f88a10d439a
https://doi.org/10.1182/asheducation-2000.1.303 -
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المؤلفون: Piroska Kopar, Steven M. Holland, John I. Gallin, Julie A. Lekstrom-Himes, Susan E. Dorman
المصدر: The Journal of Experimental Medicine
مصطلحات موضوعية: Gene isoform, Leucine zipper, Neutrophils, Immunology, myelopoiesis, Granulocyte, Biology, Cytoplasmic Granules, Polymerase Chain Reaction, DNA-binding protein, Mice, Enhancer binding, medicine, Animals, Humans, Immunology and Allergy, Transcription factor, DNA Primers, Mice, Knockout, Base Sequence, Ccaat-enhancer-binding proteins, Immunologic Deficiency Syndromes, neutrophil, Nuclear Proteins, Molecular biology, lactoferrin, DNA-Binding Proteins, medicine.anatomical_structure, granulocyte, Mutation, CCAAT-Enhancer-Binding Proteins, Brief Definitive Reports, Myelopoiesis, immunodeficiency, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df940bf73aea76ed3dabd7a6d1f8a96b
https://doi.org/10.1084/jem.189.11.1847