المؤلفون: Dana M. Lord, Julie J. Bird, Denise M. Honey, Annie Best, Anna Park, Ronnie R. Wei, Huawei Qiu

المصدر: mAbs

مصطلحات موضوعية: 0301 basic medicine, elbow mutation, antibody engineering, protein crystallization, Immunology, Antibody Affinity, protein engineering, Crystallography, X-Ray, Transforming Growth Factor beta1, TGFβ, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Protein Domains, A549 Cells, Report, Immunoglobulin G, 030220 oncology & carcinogenesis, Humans, Immunology and Allergy, affinity, Single-Chain Antibodies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb0416956b2ab4eb3a328c51b4270b0
https://doi.org/10.1080/19420862.2018.1426421

المؤلفون: Gale R; Center for Spoken Language Understanding, Oregon Health & Science University (OHSU), Portland, OR, United States., Bird J; Center for Spoken Language Understanding, Oregon Health & Science University (OHSU), Portland, OR, United States., Wang Y; Boston College, Chestnut Hill, MA, United States., van Santen J; Center for Spoken Language Understanding, Oregon Health & Science University (OHSU), Portland, OR, United States., Prud'hommeaux E; Boston College, Chestnut Hill, MA, United States., Dolata J; Center for Spoken Language Understanding, Oregon Health & Science University (OHSU), Portland, OR, United States., Asgari M; Center for Spoken Language Understanding, Oregon Health & Science University (OHSU), Portland, OR, United States.

المصدر: Frontiers in psychology [Front Psychol] 2021 Jul 22; Vol. 12, pp. 668401. Date of Electronic Publication: 2021 Jul 22 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101550902 Publication Model: eCollection Cited Medium: Print ISSN: 1664-1078 (Print) Linking ISSN: 16641078 NLM ISO Abbreviation: Front Psychol Subsets: PubMed not MEDLINE

المؤلفون: Chen TF; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, United States; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, United States., Sazinsky SL; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, United States., Houde D; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Ave., Boston, MA 02115, United States; Process Analytics, Codiak Biosciences, Cambridge, MA 02142, United States., DiLillo DJ; The Laboratory of Molecular Genetics and Immunology, The Rockefeller University, 1230 York Ave., New York, NY 10065, United States., Bird J; Biologics Research, Sanofi Genzyme, 49 New York Ave., Framingham, MA 01701, United States., Li KK; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, United States; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, United States., Cheng GT; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, United States., Qiu H; Biologics Research, Sanofi Genzyme, 49 New York Ave., Framingham, MA 01701, United States., Engen JR; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Ave., Boston, MA 02115, United States., Ravetch JV; The Laboratory of Molecular Genetics and Immunology, The Rockefeller University, 1230 York Ave., New York, NY 10065, United States., Wittrup KD; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, United States; Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, United States; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, United States. Electronic address: wittrup@mit.edu.

المصدر: Journal of molecular biology [J Mol Biol] 2017 Aug 04; Vol. 429 (16), pp. 2528-2541. Date of Electronic Publication: 2017 Jul 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Glycosylation* , Protein Engineering*, Immunoglobulin G/*metabolism , Immunologic Factors/*metabolism , Receptors, IgG/*metabolism , Recombinant Proteins/*metabolism, Animals ; Biophysical Phenomena ; Cell Line, Tumor ; Disease Models, Animal ; Half-Life ; Humans ; Immunoglobulin G/genetics ; Immunologic Factors/genetics ; Immunologic Factors/pharmacokinetics ; Lung Neoplasms/prevention & control ; Lung Neoplasms/secondary ; Mice ; Models, Theoretical ; Neoplasm Metastasis/prevention & control ; Phagocytosis ; Protein Binding ; Recombinant Proteins/genetics ; Recombinant Proteins/pharmacokinetics

المؤلفون: Moulin A; Sanofi Biotherapeutics, Framingham, Massachusetts, USA., Mathieu M, Lawrence C, Bigelow R, Levine M, Hamel C, Marquette JP, Le Parc J, Loux C, Ferrari P, Capdevila C, Dumas J, Dumas B, Rak A, Bird J, Qiu H, Pan CQ, Edmunds T, Wei RR

المصدر: Protein science : a publication of the Protein Society [Protein Sci] 2014 Dec; Vol. 23 (12), pp. 1698-707. Date of Electronic Publication: 2014 Sep 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal/*chemistry , Antibodies, Monoclonal/*immunology , Antibody Specificity/*immunology , Antigen-Antibody Reactions/*immunology , Transforming Growth Factor beta/*chemistry , Transforming Growth Factor beta/*immunology, Antibodies, Monoclonal, Humanized ; Antibodies, Neutralizing/chemistry ; Antibodies, Neutralizing/immunology ; Crystallography, X-Ray ; Humans ; Immunoglobulin Fab Fragments/chemistry ; Immunoglobulin Fab Fragments/immunology ; Models, Molecular ; Protein Conformation ; Protein Isoforms/chemistry ; Protein Isoforms/immunology ; Single-Chain Antibodies/chemistry ; Single-Chain Antibodies/immunology

المؤلفون: Zhou Q; Sanofi-Genzyme R&D Center, Genzyme Corporation, A Sanofi Company , Framingham, Massachusetts 01701, United States., Stefano JE, Manning C, Kyazike J, Chen B, Gianolio DA, Park A, Busch M, Bird J, Zheng X, Simonds-Mannes H, Kim J, Gregory RC, Miller RJ, Brondyk WH, Dhal PK, Pan CQ

المصدر: Bioconjugate chemistry [Bioconjug Chem] 2014 Mar 19; Vol. 25 (3), pp. 510-20. Date of Electronic Publication: 2014 Feb 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies/*chemistry , Antibodies, Monoclonal, Humanized/*pharmacology , Antineoplastic Agents/*pharmacology , Neoplasms, Experimental/*drug therapy, Animals ; Antibodies, Monoclonal, Humanized/chemistry ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Glycosylation ; Humans ; Mice ; Mice, SCID ; Molecular Structure ; Neoplasms, Experimental/pathology ; Polysaccharides/chemistry ; Sialic Acids/chemistry ; Sialic Acids/metabolism ; Sialyltransferases/chemistry ; Sialyltransferases/metabolism ; Structure-Activity Relationship ; Trastuzumab

المؤلفون: Bird J; School of Medicine, University of Maryland, College Park, MD, USA., Parente R; Psychology Department, Towson University, Towson, MD, USA.

المصدر: NeuroRehabilitation [NeuroRehabilitation] 2014; Vol. 34 (1), pp. 39-43.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: IOS Press Country of Publication: Netherlands NLM ID: 9113791 Publication Model: Print Cited Medium: Internet ISSN: 1878-6448 (Electronic) Linking ISSN: 10538135 NLM ISO Abbreviation: NeuroRehabilitation Subsets: MEDLINE

مواضيع طبية MeSH: Emotions* , Recognition, Psychology*, Brain Injuries/*psychology , Nonverbal Communication/*psychology, Acoustic Stimulation ; Facial Expression ; Gestures ; Humans

المؤلفون: Stefano JE; Protein Engineering, Genzyme Corporation (A Sanofi Company), Framingham, MA, USA. jstefano@genzyme.com, Bird J, Kyazike J, Cheng AW, Boudanova E, Dwyer M, Hou L, Qiu H, Matthews G, O'Callaghan M, Pan CQ

المصدر: Bioconjugate chemistry [Bioconjug Chem] 2012 Dec 19; Vol. 23 (12), pp. 2354-64. Date of Electronic Publication: 2012 Dec 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE

مواضيع طبية MeSH: Polyethylene Glycols/*chemistry , Vascular Endothelial Growth Factor A/*antagonists & inhibitors , Vascular Endothelial Growth Factor Receptor-1/*chemistry, Copper/chemistry ; Cysteine/chemistry ; Dimerization ; Disulfides/chemistry ; HEK293 Cells ; Humans ; Kinetics ; Molecular Targeted Therapy ; Molecular Weight ; Oxidation-Reduction ; Protein Conformation ; Protein Stability ; Protein Structure, Tertiary ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Structure-Activity Relationship ; Surface Plasmon Resonance ; Vascular Endothelial Growth Factor A/chemistry ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor Receptor-1/genetics