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1
المؤلفون: Aisha S Kuforiji, Maya Mikami, Charles W. Emala, Julie J. Hwang, Gene T. Yocum, Jennifer Danielsson
المصدر: Am J Physiol Lung Cell Mol Physiol
مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Male, Physiology, Regulatory T cell, Catechols, Inflammation, Cell Count, Ginger, T-Lymphocytes, Regulatory, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Antigens, CD, Physiology (medical), medicine, Cyclic AMP, Animals, Antigens, Dermatophagoides, Lung, Asthma, business.industry, Plant Extracts, Airway Resistance, Airway inflammation, NF-kappa B, Phosphodiesterase, Cell Biology, Shogaol, Pneumonia, Asthma model, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, Immunology, Female, Interleukin-4, medicine.symptom, Bronchial Hyperreactivity, business, Bronchoalveolar Lavage Fluid, Signal Transduction, Research Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccde6a0f82138a9a390fb7f3c5254347
https://pubmed.ncbi.nlm.nih.gov/31800263 -
2دورية أكاديمية
المؤلفون: Young JR, Evans MK, Hwang J, Kritzer MD, Kellner CH; Medical University of South Carolina, Charleston, SC., Weiner RD; From the Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine.
المصدر: The journal of ECT [J ECT] 2024 Jun 20. Date of Electronic Publication: 2024 Jun 20.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9808943 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-4112 (Electronic) Linking ISSN: 10950680 NLM ISO Abbreviation: J ECT Subsets: MEDLINE
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3دورية أكاديمية
المؤلفون: So S; Stem Cell Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Lee Y; Stem Cell Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Choi J; Stem Cell Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Kang S; Stem Cell Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Lee JY; Department of Convergence Medicine, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Hwang J; Stem Cell Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Shin J; Stem Cell Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Dutton JR; Stem Cell Institute, University of Minnesota, Minneapolis, Minnesota, United States of America., Seo EJ; Medical Genetics Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Lee BH; Medical Genetics Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Kim CJ; Department of Pathology, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Mitalipov S; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, Oregon, United States of America., Oh SJ; Department of Convergence Medicine, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Kang E; Stem Cell Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Department of Convergence Medicine, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
المصدر: PloS one [PLoS One] 2020 May 12; Vol. 15 (5), pp. e0233057. Date of Electronic Publication: 2020 May 12 (Print Publication: 2020).
نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
مواضيع طبية MeSH: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/*analogs & derivatives , Pluripotent Stem Cells/*cytology , Pluripotent Stem Cells/*drug effects , rho-Associated Kinases/*antagonists & inhibitors, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/pharmacology ; Amides/pharmacology ; Cell Differentiation/drug effects ; Cell Line ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/drug effects ; Humans ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/drug effects ; Neural Crest/cytology ; Neural Crest/drug effects ; Protein Kinase Inhibitors/pharmacology ; Pyridines/pharmacology ; Retinal Pigment Epithelium/cytology ; Retinal Pigment Epithelium/drug effects ; Stem Cell Research
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4دورية أكاديمية
المؤلفون: Chakrabarti R; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. ykang@princeton.edu rumela@vet.upenn.edu.; Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA., Celià-Terrassa T; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA., Kumar S; Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA., Hang X; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA., Wei Y; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA., Choudhury A; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA., Hwang J; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA., Peng J; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA., Nixon B; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Grady JJ; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA., DeCoste C; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA., Gao J; Department of Pathology, NYU Langone Medical Center, New York City, NY 10016, USA., van Es JH; Hubrecht Institute and University Medical Center Utrecht, Utrecht, Netherlands., Li MO; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Aifantis I; Department of Pathology, NYU Langone Medical Center, New York City, NY 10016, USA., Clevers H; Department of Pathology, NYU Langone Medical Center, New York City, NY 10016, USA., Kang Y; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. ykang@princeton.edu rumela@vet.upenn.edu.; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.
المصدر: Science (New York, N.Y.) [Science] 2018 Jun 29; Vol. 360 (6396). Date of Electronic Publication: 2018 May 17.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
مواضيع طبية MeSH: Intercellular Signaling Peptides and Proteins/*metabolism , Macrophages/*physiology , Mammary Glands, Animal/*cytology , Mammary Glands, Animal/*growth & development , Receptors, Notch/*metabolism , Stem Cell Niche/*physiology , Stem Cells/*physiology, Animals ; Calcium-Binding Proteins ; Cell Count ; Female ; Gene Knockout Techniques ; Intercellular Signaling Peptides and Proteins/genetics ; Ligands ; Macrophages/cytology ; Mammary Glands, Animal/metabolism ; Mice ; Mice, Knockout ; Morphogenesis ; Signal Transduction ; Stem Cells/cytology ; Stromal Cells/cytology ; Stromal Cells/physiology ; Wnt Proteins/metabolism
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5دورية أكاديمية
المؤلفون: White EC; Department of Radiation Oncology, Kaiser Permanente Southern California, Los Angeles Medical Center, Los Angeles, CA., Khodayari B, Erickson KT, Lien WW, Hwang-Graziano J, Rao AR
المصدر: American journal of clinical oncology [Am J Clin Oncol] 2017 Aug; Vol. 40 (4), pp. 386-392.
نوع المنشور: Comparative Study; Journal Article
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8207754 Publication Model: Print Cited Medium: Internet ISSN: 1537-453X (Electronic) Linking ISSN: 02773732 NLM ISO Abbreviation: Am J Clin Oncol Subsets: MEDLINE
مواضيع طبية MeSH: Anus Neoplasms/*therapy , Carcinoma, Squamous Cell/*therapy , Chemoradiotherapy/*adverse effects , HIV Infections/*complications, Adult ; Aged ; Aged, 80 and over ; Anal Canal/pathology ; Anus Neoplasms/mortality ; Anus Neoplasms/virology ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/virology ; Disease-Free Survival ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Radiotherapy Dosage ; Retrospective Studies ; Treatment Outcome
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6دورية أكاديمية
المؤلفون: Muranen T; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA., Iwanicki MP; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA., Curry NL; Division of Endocrinology, Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA., Hwang J; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA., DuBois CD; Division of Endocrinology, Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA., Coloff JL; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA., Hitchcock DS; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA., Clish CB; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA., Brugge JS; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA., Kalaany NY; Division of Endocrinology, Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA.
المصدر: Nature communications [Nat Commun] 2017 Jan 10; Vol. 8, pp. 13989. Date of Electronic Publication: 2017 Jan 10.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
مواضيع طبية MeSH: Epithelial Cells/*physiology , Extracellular Matrix/*metabolism , Integrin beta4/*metabolism , Laminin/*metabolism, Adipose Tissue/cytology ; Adipose Tissue/metabolism ; Animals ; Cell Line ; Cell Survival/physiology ; Epithelial Cells/cytology ; Epithelial Cells/drug effects ; Female ; Fibroblasts/metabolism ; Humans ; Integrin beta4/genetics ; Laminin/pharmacology ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Mice, Inbred Strains ; Phosphatidylinositol 3-Kinases/metabolism ; Starvation
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7دورية أكاديمية
المؤلفون: Muranen T; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, Boston, Massachusetts., Selfors LM; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, Boston, Massachusetts., Hwang J; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, Boston, Massachusetts., Gallegos LL; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, Boston, Massachusetts., Coloff JL; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, Boston, Massachusetts., Thoreen CC; Department of Biology, Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Koch Institute for Integrative Cancer Research, Cambridge, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Kang SA; Department of Biology, Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Koch Institute for Integrative Cancer Research, Cambridge, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Sabatini DM; Department of Biology, Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Koch Institute for Integrative Cancer Research, Cambridge, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Mills GB; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Brugge JS; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, Boston, Massachusetts. joan_brugge@hms.harvard.edu.
المصدر: Cancer research [Cancer Res] 2016 Dec 15; Vol. 76 (24), pp. 7168-7180. Date of Electronic Publication: 2016 Oct 20.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing/*metabolism , Drug Resistance, Neoplasm/*physiology , Extracellular Signal-Regulated MAP Kinases/*metabolism , Neoplasms, Experimental/*pathology , Phosphoproteins/*metabolism , Proto-Oncogene Proteins c-myc/*metabolism , p38 Mitogen-Activated Protein Kinases/*metabolism, Animals ; Blotting, Western ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Female ; Fluorescent Antibody Technique ; Heterografts ; Humans ; MAP Kinase Signaling System/drug effects ; Mice ; Mice, Inbred NOD ; Microscopy, Confocal ; Neoplasms, Experimental/metabolism ; Phosphoinositide-3 Kinase Inhibitors ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Mas ; Signal Transduction/drug effects ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; Transcription Factors ; YAP-Signaling Proteins
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8دورية أكاديمية
المؤلفون: Lu SM; Department of Radiation Oncology, Kaiser Permanente Southern California, Los Angeles, CA, USA. Electronic address: sharon.m.lu@gmail.com., Chang-Halpenny C; Department of Radiation Oncology, Kaiser Permanente Southern California, Los Angeles, CA, USA., Hwang-Graziano J; Department of Radiation Oncology, Kaiser Permanente Southern California, Los Angeles, CA, USA.
المصدر: Gynecologic oncology [Gynecol Oncol] 2015 Apr; Vol. 137 (1), pp. 28-33. Date of Electronic Publication: 2015 Feb 07.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0365304 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6859 (Electronic) Linking ISSN: 00908258 NLM ISO Abbreviation: Gynecol Oncol Subsets: MEDLINE
مواضيع طبية MeSH: Antineoplastic Combined Chemotherapy Protocols/*administration & dosage , Carcinoma, Endometrioid/*drug therapy , Carcinoma, Endometrioid/*radiotherapy , Endometrial Neoplasms/*drug therapy , Endometrial Neoplasms/*radiotherapy, Adult ; Aged ; Carboplatin/administration & dosage ; Carcinoma, Endometrioid/pathology ; Carcinoma, Endometrioid/surgery ; Chemoradiotherapy, Adjuvant ; Cisplatin/administration & dosage ; Disease Progression ; Doxorubicin/administration & dosage ; Endometrial Neoplasms/pathology ; Endometrial Neoplasms/surgery ; Female ; Humans ; Middle Aged ; Neoplasm Recurrence, Local/pathology ; Neoplasm Staging ; Paclitaxel/administration & dosage ; Retrospective Studies ; Treatment Outcome
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9دورية أكاديمية
المؤلفون: Chakrabarti R; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA., Wei Y; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA., Hwang J; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA., Hang X; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA., Andres Blanco M; 1] Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA [2] Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA., Choudhury A; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA., Tiede B; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA., Romano RA; Department of Biochemistry, Center of Excellence in Bioinformatics and Life Sciences, State University of New York at Buffalo, Buffalo, New York 14203, USA., DeCoste C; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA., Mercatali L; Osteoncology and Rare Tumors Center, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), IRCCS, 47014 Meldola, Italy., Ibrahim T; Osteoncology and Rare Tumors Center, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), IRCCS, 47014 Meldola, Italy., Amadori D; Osteoncology and Rare Tumors Center, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), IRCCS, 47014 Meldola, Italy., Kannan N; Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada., Eaves CJ; Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada., Sinha S; Department of Biochemistry, Center of Excellence in Bioinformatics and Life Sciences, State University of New York at Buffalo, Buffalo, New York 14203, USA., Kang Y; 1] Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA [2] Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey 08903, USA.
المصدر: Nature cell biology [Nat Cell Biol] 2014 Oct; Vol. 16 (10), pp. 1004-15, 1-13. Date of Electronic Publication: 2014 Sep 21.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
بيانات الدورية: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
مواضيع طبية MeSH: Wnt Signaling Pathway*, Breast Neoplasms/*metabolism , Frizzled Receptors/*metabolism , Mammary Glands, Human/*metabolism , Stem Cells/*metabolism , Transcription Factors/*metabolism , Tumor Suppressor Proteins/*metabolism, Animals ; Blotting, Western ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Epithelial Cells/metabolism ; Frizzled Receptors/genetics ; Gene Expression Regulation, Neoplastic ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Humans ; Interleukin Receptor Common gamma Subunit/deficiency ; Interleukin Receptor Common gamma Subunit/genetics ; Mammary Glands, Animal/cytology ; Mammary Glands, Animal/metabolism ; Mammary Glands, Human/cytology ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Mice, Transgenic ; Microscopy, Confocal ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Oligonucleotide Array Sequence Analysis ; Reverse Transcriptase Polymerase Chain Reaction ; Stem Cells/cytology ; Transcription Factors/genetics ; Transplantation, Heterologous ; Tumor Suppressor Proteins/genetics
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10دورية أكاديمية
المؤلفون: Chang-Halpenny CN; Department of Radiation Oncology, Kaiser Permanente Southern California, Los Angeles CA, USA. Electronic address: cnchang@gmail.com., Natarajan S, Hwang-Graziano J
المصدر: Gynecologic oncology [Gynecol Oncol] 2013 Dec; Vol. 131 (3), pp. 598-603. Date of Electronic Publication: 2013 Oct 14.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0365304 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6859 (Electronic) Linking ISSN: 00908258 NLM ISO Abbreviation: Gynecol Oncol Subsets: MEDLINE
مواضيع طبية MeSH: Endometrial Neoplasms/*pathology , Endometrial Neoplasms/*therapy , Polyps/*pathology , Polyps/*therapy, Adenocarcinoma, Clear Cell/pathology ; Adenocarcinoma, Clear Cell/therapy ; Aged ; Aged, 80 and over ; Carcinoma, Papillary/pathology ; Carcinoma, Papillary/therapy ; Chemoradiotherapy, Adjuvant ; Chemotherapy, Adjuvant ; Cystadenocarcinoma, Serous/pathology ; Cystadenocarcinoma, Serous/therapy ; Female ; Humans ; Hysterectomy ; Middle Aged ; Neoplasm Staging ; Radiotherapy, Adjuvant ; Retrospective Studies ; Treatment Outcome