المؤلفون: Rikesh M. Rajani, Julien Ratelade, Valérie Domenga-Denier, Yoshiki Hase, Hannu Kalimo, Raj N. Kalaria, Anne Joutel

المصدر: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-14 (2019)

مصطلحات موضوعية: CADASIL, Small vessel disease, Blood brain barrier, White matter lesions, Pericytes, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-019-0844-x; https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/6ffdfc0c91ff45dfad7b2368eaf0bb03

المؤلفون: Julien Ratelade, Jeffrey L Bennett, A S Verkman

المصدر: PLoS ONE, Vol 6, Iss 11, p e27412 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3208637?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/7d217e401d794bab8d10c16013702077

المؤلفون: Monara Kaelle Servulo Cruz Angelim, Nicholas R. Klug, Julien Ratelade, Mark T. Nelson, Valérie Domenga-Denier, Fabrice Dabertrand, Anne Joutel, Damiano Lombardi, Rustam Al-Shahi Salman, Colin Smith, Jean-Frédéric Gerbeau

المساهمون: Institut de psychiatrie et neurosciences de Paris (IPNP - U1266 Inserm), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), University of Vermont [Burlington], COmputational Mathematics for bio-MEDIcal Applications (COMMEDIA), Inria de Paris, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire Jacques-Louis Lions (LJLL (UMR_7598)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), University of Colorado Anschutz [Aurora], University of Edinburgh, Inria Siège, Institut National de Recherche en Informatique et en Automatique (Inria), University of Manchester [Manchester], Université Sorbonne Paris Cité (USPC), This work was supported by Fondation Leducq (Transatlantic Network of Excellence on the Pathogenesis of Small Vessel Disease of the Brain) to AJ and MTN, the European Union (Horizon 2020 Research and Innovation Programme SVDs@target under the grant agreement n° 666881), the French National Agency of Research (ANR I-Can) and the French Fondation for Rare Diseases to AJ, the National Institute of Neurological Disorders and Stroke (NINDS) and National Institute of Aging (NIA) (R01NS110656), the National Institutes of Health under Award Number R35HL140027 and the Henry M. Jackson Foundation for the Advancement of Military Medicine (HU0001-18-2-0016) to MTN. The LINCHPIN study was funded by UK Medical Research Council (MRC) and The Stroke Association. The Edinburgh Brain Bank, part of the MRC UK Brain Bank Network, curates the brain tissue from LINCHPIN study tissue donors and controls who died suddenly from non-neurological conditions. The Edinburgh Brain Bank is funded by both MRC and The Stroke Association., Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Martinez Rico, Clara, Institute of Psychiatry and Neurosciences of Paris, INSERM U1266, University of Paris, Paris, France., Department of Pharmacology, College of Medicine, University of Vermont, Burlington, VT., Inria Paris, Sorbonne University, Laboratory Jacques-Louis Lions, Paris, France, Institute of Psychiatry and Neurosciences of Paris, INSERM U1266, University of Paris, Paris, France, Department of Pharmacology, College of Medicine, University of Vermont, Burlington, VT, Department of Anesthesiology, Department of Pharmacology, Anschutz Medical Campus, University of Colorado, Aurora, CO, Institute of Psychiatry and Neurosciences of Paris, INSERM U1266, University of Paris, Paris, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK, Division of Cardiovascular Sciences, University of Manchester, Manchester, UK, DHU NeuroVasc, Sorbonne Paris Cité, Paris, France., Institut de psychiatrie et neurosciences de Paris (IPNP - U1266 Inserm - Paris Descartes), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Circulation
Circulation, American Heart Association, 2020, 141 (25), pp.2078-2094. ⟨10.1161/CIRCULATIONAHA.119.040963⟩
Circulation, 2020, 141 (25), pp.2078-2094. ⟨10.1161/CIRCULATIONAHA.119.040963⟩
Ratelade, J, Klug, N, Lombardi, D, Cruz Angelim, MKS, Dabertrand, F, Domenga-Denier, V, Salam, RA & Nelson, M 2020, ' Reducing Hypermuscularization of the Transitional Segment Between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage. ', Circulation . https://doi.org/10.1161/circulationaha.119.040963
Circulation, American Heart Association, 2020, Epub ahead of print. ⟨10.1161/CIRCULATIONAHA.119.040963⟩
Ratelade, J, Klug, N R, Lombardi, D, Angelim, M K S C, Dabertrand, F, Domenga-denier, V, Al-shahi Salman, R, Smith, C, Gerbeau, J, Nelson, M T & Joutel, A 2020, ' Reducing Hypermuscularization of the Transitional Segment between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage ', Circulation . https://doi.org/10.1161/CIRCULATIONAHA.119.040963

مصطلحات موضوعية: Pathology, [SDV]Life Sciences [q-bio], Gene Expression, Retinal Neovascularization, Hypermuscularization, Muscle, Smooth, Vascular, Mice, 0302 clinical medicine, Transitional segment, Receptor, Notch3, Mice, Knockout, Collagen IV, 0303 health sciences, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Hyperplasia, Immunohistochemistry, Molecular Imaging, 3. Good health, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, cardiovascular system, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Disease Susceptibility, Cardiology and Cardiovascular Medicine, Collagen Type IV, medicine.medical_specialty, Genotype, Myocytes, Smooth Muscle, Retina, Article, Mural cell, Contractility, 03 medical and health sciences, Downregulation and upregulation, Arteriole, Physiology (medical), medicine.artery, Genetic model, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, medicine, Animals, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], cardiovascular diseases, Cerebral Hemorrhage, 030304 developmental biology, Intracerebral hemorrhage, business.industry, Notch3, medicine.disease, Disease Models, Animal, Microvessels, Mutation, business, Biomarkers, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0e60f78ce286114551661d78cc8e5d

المؤلفون: Anne Joutel, Søren Christensen, Lamia Ghezali, Jan Torleif Pedersen, Julien Ratelade, Céline Baron-Menguy, Carmen Capone, Lars Østergaard Pedersen, Valérie Domenga-Denier

المصدر: Annals of Neurology. 84:246-259

مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, business.industry, Cerebral arteries, Vasodilation, medicine.disease, Hyperintensity, Pathogenesis, Leukoencephalopathy, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Neurology, Cerebral blood flow, medicine, Neurology (clinical), CADASIL, Receptor, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0d43d91041fb0a2df1b9649efb32418a
https://doi.org/10.1002/ana.25284

المؤلفون: Emmanuelle Plaisier, Nicolas Mezouar, Ambre Rochey, Anne Joutel, Julien Ratelade, Valérie Domenga-Denier

المساهمون: Génétique et Physiopathologie des Maladies Cérébro-Vasculaires (U1161 / UMR_S 1161), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Des Maladies Rénales Rares aux Maladies Fréquentes, Remodelage et Réparation, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), DHU NeuroVasc Sorbonne Paris-Cité, Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Dupuis, Christine

المصدر: The Journal of Pathology
The Journal of pathology and bacteriology
The Journal of pathology and bacteriology, John Wiley & Sons, 2018, 244 (4), pp.408-420. ⟨10.1002/path.5023⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: Cerebral Hemorrhage, Pathology, Time Factors, [SDV]Life Sciences [q-bio], Penetrance, Degeneration (medical), MESH: Mice, Knockout, Muscle, Smooth, Vascular, MESH: Blood-Brain Barrier, chemistry.chemical_compound, 0302 clinical medicine, MESH: Penetrance, MESH: Animals, MESH: Endothelial Cells, MESH: Peptide Fragments, Stroke, Mice, Knockout, MESH: Genetic Predisposition to Disease, intracerebral haemorrhage, MESH: Myocytes, Smooth Muscle, MESH: Muscle, Smooth, Vascular, 3. Good health, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, Blood-Brain Barrier, retinal imaging, Disease Progression, MESH: Disease Progression, Collagen Type IV, medicine.medical_specialty, Mice, 129 Strain, Retinal Artery, COL4A1, Myocytes, Smooth Muscle, COL4A2, MESH: Stroke, Pathology and Forensic Medicine, 03 medical and health sciences, MESH: Mice, 129 Strain, MESH: Mice, Inbred C57BL, MESH: Cell Proliferation, Parenchyma, medicine, Animals, Genetic Predisposition to Disease, Pathological, MESH: Collagen Type IV, smooth muscle cell, Cell Proliferation, Cerebral Hemorrhage, Basement membrane, Retina, MESH: Retinal Artery, business.industry, MESH: Time Factors, Endothelial Cells, Retinal, medicine.disease, basement membrane, Peptide Fragments, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, chemistry, MESH: Disease Models, Animal, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85ded6d977fa4727e5ff262dc4f880b

المؤلفون: Lamia, Ghezali, Carmen, Capone, Céline, Baron-Menguy, Julien, Ratelade, Søren, Christensen, Lars, Østergaard Pedersen, Valérie, Domenga-Denier, Jan Torleif, Pedersen, Anne, Joutel

المصدر: Annals of neurology. 84(2)

مصطلحات موضوعية: Male, Mice, HEK293 Cells, Cerebrovascular Circulation, Animals, Humans, CADASIL, Mice, Transgenic, Immunotherapy, Receptor, Notch3, Extracellular Matrix, Protein Binding, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ff1cacebb82288db4ec1eb6632380e31
https://pubmed.ncbi.nlm.nih.gov/30014602

المؤلفون: Jeffrey W. Ralph, Andrea Rossi, Aaron Lewis, Andrew W. Bollen, Rabia Malik, Julien Ratelade, Bruce A.C. Cree, Alan S. Verkman

المصدر: Muscle & Nerve. 50:859-862

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Neuromyelitis optica, medicine.diagnostic_test, biology, Physiology, business.industry, Magnetic resonance imaging, medicine.disease, Immunofluorescence, Spinal cord, Cellular and Molecular Neuroscience, Aquaporin 4, medicine.anatomical_structure, Physiology (medical), Muscle fiber necrosis, medicine, biology.protein, Creatine kinase, Neurology (clinical), Established diagnosis, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::81e8bfea035ace8c586775f74ae61a33
https://doi.org/10.1002/mus.24298

المؤلفون: Julien Ratelade, Alan S. Verkman, Byung-Ju Jin, Alex J. Smith

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: Biology, Article, Cell membrane, Mice, Cell Movement, Quantum Dots, medicine, Cell Adhesion, Image Processing, Computer-Assisted, Animals, Humans, Protein Isoforms, Pseudopodia, Cell adhesion, Research Articles, Cells, Cultured, Aquaporin 4, Mice, Knockout, Brain Neoplasms, Cell Membrane, Cell migration, Cell Biology, Adhesion, Models, Theoretical, Subcellular localization, Cell biology, Extracellular Matrix, medicine.anatomical_structure, Astrocytes, sense organs, Lamellipodium, Protein Multimerization, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0162fc3864d26f9138f980e63abe4a5
http://europepmc.org/articles/PMC3926963

المؤلفون: Alan S. Verkman, Julien Ratelade

المصدر: The international journal of biochemistry & cell biology, vol 44, iss 9

مصطلحات موضوعية: Biochemistry & Molecular Biology, Multiple Sclerosis, Medical Physiology, Central nervous system, Complement, Autoimmunity, Neurodegenerative, Medical Biochemistry and Metabolomics, Autoimmune Disease, Biochemistry, Article, Myelin, Organ Culture Techniques, medicine, Animals, Humans, 2.1 Biological and endogenous factors, Aetiology, Eye Disease and Disorders of Vision, Aquaporin 4, Neuromyelitis optica, Water transport, NMO, Chemistry, Neuromyelitis Optica, Neurosciences, Cell Biology, medicine.disease, Oligodendrocyte, Brain Disorders, Devic's disease, medicine.anatomical_structure, Immunoglobulin G, Neurological, Immunology, Biochemistry and Cell Biology, sense organs, Astrocyte, Neuron death, Aquaporin-4, Biotechnology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1108c6743618c03ce7806c08e9e515
https://doi.org/10.1016/j.biocel.2012.06.013

المؤلفون: Marios C. Papadopoulos, Samira Saadoun, Hua Zhang, Alan S. Verkman, Jeffrey Bennett, Julien Ratelade

المصدر: Acta Neuropathologica. 123:861-872

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Article, Immunoglobulin G, Pathology and Forensic Medicine, Natural killer cell, Lesion, Mice, Cellular and Molecular Neuroscience, medicine, Animals, Humans, Cells, Cultured, Myelin Sheath, Aquaporin 4, Mice, Knockout, Antibody-dependent cell-mediated cytotoxicity, Neuromyelitis optica, biology, Neuromyelitis Optica, Antibody-Dependent Cell Cytotoxicity, Antibodies, Monoclonal, Complement System Proteins, medicine.disease, Killer Cells, Natural, Disease Models, Animal, medicine.anatomical_structure, Spinal Cord, Astrocytes, Immunology, Monoclonal, biology.protein, Neurology (clinical), medicine.symptom, Astrocyte

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d247f62ae9e383acae8b64b502dc8c3
https://doi.org/10.1007/s00401-012-0986-4