المؤلفون: Lisa Zadjura, Ivette Medina, Rita L. Civiello, Eugene V. Genovesi, Celia D’Arienzo, Sandra A. Dando, H. Belgin Gulgeze, Anthony M. Marino, Keith D. Combrink, X. Alan Wang, Richard J. Colonno, Christopher Cianci, Nicholas A. Meanwell, Kuo-Long Yu, Richard A. Dalterio, Mark Krystal, Lucinda Lamb, Zheng Yang, J. J. Kim Wright, Kathleen F. Kadow, Brian Lee Venables, Junius Clarke, Zhufang Li, Ny Sin

المصدر: Bioorganic & Medicinal Chemistry Letters. 17:895-901

مصطلحات موضوعية: Chemical Phenomena, Membrane permeability, Paramyxoviridae, Clinical Biochemistry, Biological Availability, Pharmaceutical Science, Respiratory Syncytial Virus Infections, In Vitro Techniques, Antiviral Agents, Biochemistry, Virus, Mice, Structure-Activity Relationship, Dogs, Cytopathogenic Effect, Viral, Oral administration, Drug Discovery, Animals, Humans, Potency, Sigmodontinae, Cotton rat, Mononegavirales, Molecular Biology, Mice, Inbred BALB C, biology, Chemistry, Physical, Chemistry, Organic Chemistry, biology.organism_classification, Virology, Rats, Bioavailability, Macaca fascicularis, Respiratory Syncytial Virus, Human, Microsomes, Liver, Molecular Medicine, Benzimidazoles, Caco-2 Cells, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f0b15de4e6b963a15896b9c356593f
https://doi.org/10.1016/j.bmcl.2006.11.063

المؤلفون: Eugene V. Genovesi, Yi Zhang, Ashok K. Trehan, Philip R. Wyde, Ivette Medina, Nicholas A. Meanwell, Kathleen F. Kadow, Xiangdong Alan Wang, Rita L. Civiello, Christopher Cianci, Zhiwei Yin, H. Belgin Gulgeze, Keith D. Combrink, Bradley C. Pearce, Junius Clarke, Lucinda Lamb, Kuo-Long Yu, Mark Krystal

المصدر: Bioorganic & Medicinal Chemistry Letters. 16:1115-1122

مصطلحات موضوعية: Tertiary amine, Paramyxoviridae, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Antiviral Agents, Membrane Fusion, Biochemistry, Virus, Mice, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, Animals, Sigmodontinae, Cotton rat, Amines, Mononegavirales, Molecular Biology, Molecular Structure, biology, Ribavirin, Organic Chemistry, Water, biology.organism_classification, Rats, Respiratory Syncytial Viruses, Solubility, chemistry, Systemic administration, Molecular Medicine, Benzimidazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e43e7214e5a9a067bd12b1792d30b1
https://doi.org/10.1016/j.bmcl.2005.11.109

المؤلفون: Marco Dodier, Rebecca L. Drain, Alain Martel, Joanne J. Bronson, Kathleen W. Mosure, Patrice Gill, Stephan Roy, Terry M. Stickle, John W. Russell, Danielle Beaulieu, Cheryl Ferraro, Lawrence B. Snyder, Hyekyung Yang, Susan Chaniewski, Junius Clarke, Ken Denbleyker, Kenneth S. Santone, Stanley D'andrea, MaryBeth Frosco, Anne Marinier, Claude A. Quesnelle, Glen A. Warr, John F. Barrett, Jay O. Knipe, Dennis Taylor

المصدر: Bioorganic & Medicinal Chemistry Letters. 15:2728-2733

مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Gram-positive bacteria, Clinical Biochemistry, Antibiotics, Biphenyl derivatives, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Molecular Biology, Antibacterial agent, biology, Chemistry, Organic Chemistry, Isoxazoles, biology.organism_classification, Haemophilus influenzae, Anti-Bacterial Agents, Rats, Molecular Medicine, Antibacterial activity, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e23e62ba06a9197abb918ac020d2739
https://doi.org/10.1016/j.bmcl.2005.04.003

المؤلفون: Jan Willem Thuring, Ny Sin, Kuo-Long Yu, Mark Krystal, Rita L. Civiello, Nicholas A. Meanwell, Eugene V. Genovesi, Anthony M. Marino, Keith D. Combrink, Christopher Cianci, Brian Lee Venables, Junius Clarke, Lisa Zadjura, Ivette Medina, Kathleen F. Kadow, H. Belgin Gulgeze, Zheng Yang, X. Alan Wang, Lucinda Lamb

المصدر: Bioorganicmedicinal chemistry letters. 19(16)

مصطلحات موضوعية: Isatin, Paramyxoviridae, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Antiviral Agents, Virus, Sulfone, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Cell Line, Tumor, Drug Discovery, Oximes, Animals, Humans, Mononegavirales, Molecular Biology, Mice, Inbred BALB C, biology, Organic Chemistry, biology.organism_classification, Oxime, Rats, Respiratory Syncytial Viruses, chemistry, Microsomes, Liver, Molecular Medicine, Benzimidazoles, Caco-2 Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b35b467fe4bad38b060ed53cb8a710
https://pubmed.ncbi.nlm.nih.gov/19596574

المؤلفون: Rita L. Civiello, Kuo-Long Yu, Mark Krystal, Eugene V. Genovesi, Lisa Zadjura, Zheng Yang, Ivette Medina, Jan Willem Thuring, Junius Clarke, Nicholas A. Meanwell, Zhufang Li, Kathleen F. Kadow, David R. Langley, Keith D. Combrink, Yi Zhang, Christopher Cianci, Lucinda Lamb, Zhiwei Yin, H. Belgin Gulgeze, Bradley C. Pearce

المصدر: Bioorganicmedicinal chemistry letters. 17(17)

مصطلحات موضوعية: Models, Molecular, Benzimidazole, Stereochemistry, Chemistry, Pharmaceutical, Clinical Biochemistry, Substituent, Molecular Conformation, Pharmaceutical Science, Electrons, Respiratory Syncytial Virus Infections, Benzothiazine, Ring (chemistry), Biochemistry, Antiviral Agents, chemistry.chemical_compound, Inhibitory Concentration 50, Drug Discovery, Side chain, Moiety, Humans, Oxindole, Molecular Biology, Organic Chemistry, Benzoxazole, Respiratory Syncytial Viruses, chemistry, Models, Chemical, Drug Design, Molecular Medicine, Benzimidazoles, Viral Fusion Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d06163d4bd52be523754844a67da7d0
https://pubmed.ncbi.nlm.nih.gov/17616396

المؤلفون: Junius Clarke, Susan Chaniewski, Alain Martel, Joanne J. Bronson, MaryBeth Frosco, Glen A. Warr, Kathleen W. Mosure, Lawrence B. Snyder, Cheryl Ferraro, Stanley D'andrea, Ken Denbleyker, Patrice Gill, Stephan Roy, Claude A. Quesnelle, Terry M. Stickle, Rebecca L. Drain, Marco Dodier, John F. Barrett, Jay O. Knipe, John W. Russell, Danielle Beaulieu, Anne Marinier, Hyekyung Yang, Kenneth S. Santone, Dennis Taylor

المصدر: 19th International Congress on Heterocyclic Chemistry

مصطلحات موضوعية: chemistry.chemical_classification, Alicyclic compound, chemistry, Organic chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::473bc30d6f1159c1508b3c67afbede04
https://doi.org/10.1016/b978-0-08-044304-1.50285-9

المؤلفون: J. J. Kim Wright, Keith D. Combrink, H. Belgin Gulgeze, Eugene V. Genovesi, Sandra A. Dando, Richard A. Dalterio, Celia D’Arienzo, Brian Lee Venables, Junius Clarke, Lisa Zadjura, Kuo-Long Yu, Lucinda Lamb, Christopher Cianci, Mark Krystal, Ivette Medina, Richard J. Colonno, Ny Sin, Zhufang Li, Rita L. Civiello, Anthony M. Marino, Nicholas A. Meanwell, Kathleen F. Kadow, Zheng Yang, X. Alan Wang

المصدر: Bioorganic & Medicinal Chemistry Letters. 17:2385

مصطلحات موضوعية: Chemistry, Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Respiratory system, Molecular Biology, Biochemistry, Virology, Virus, Bioavailability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a3631113fb5fdc2be16660ebf488560e
https://doi.org/10.1016/j.bmcl.2007.03.020