المؤلفون: Jutzi JS; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Delwel R; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands., Zeiser R; Department of Hematology, Oncology, and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg, Germany.; CIBSS Centre for Integrative Biological Signaling Studies, Freiburg, Germany., Marneth AE; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Nijmegen, Netherlands.

المصدر: Frontiers in molecular biosciences [Front Mol Biosci] 2024 Mar 13; Vol. 11, pp. 1388983. Date of Electronic Publication: 2024 Mar 13 (Print Publication: 2024).

نوع المنشور: Editorial

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101653173 Publication Model: eCollection Cited Medium: Print ISSN: 2296-889X (Print) Linking ISSN: 2296889X NLM ISO Abbreviation: Front Mol Biosci Subsets: PubMed not MEDLINE

المؤلفون: Staehle AM; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Peeken JC; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.; Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany., Vladimirov G; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Hoeness ME; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Bojtine Kovacs S; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Karantzelis N; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Gruender A; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Koellerer C; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Jutzi JS; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Pahl HL; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany. heike.pahl@klinikum.uni-freiburg.de., Staehle HF; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.

المصدر: Leukemia [Leukemia] 2023 Apr; Vol. 37 (4), pp. 919-923. Date of Electronic Publication: 2023 Jan 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/genetics , Myeloproliferative Disorders*/genetics, Animals ; Mice ; Gene Expression Regulation ; Histone Demethylases/genetics ; Janus Kinase 2/genetics ; Janus Kinase 2/metabolism ; Mice, Transgenic ; Mutation ; NF-E2 Transcription Factor, p45 Subunit/genetics ; NF-E2 Transcription Factor, p45 Subunit/metabolism ; Humans

المؤلفون: Jutzi JS; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Marneth AE; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Jiménez-Santos MJ; Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Hem J; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Guerra-Moreno A; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Rolles B; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Bhatt S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pharmacy, National University of Singapore, Singapore, Singapore., Myers SA; Center for Autoimmunity and Inflammation, La Jolla Institute for Immunology, La Jolla, CA, 92037, USA., Carr SA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hong Y; Department of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3083, Australia., Pozdnyakova O; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., van Galen P; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Al-Shahrour F; Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Nam AS; Weill Cornell Medicine, New York City, N.Y., USA., Mullally A; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. ann_mullally@dfci.harvard.edu.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. ann_mullally@dfci.harvard.edu.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA. ann_mullally@dfci.harvard.edu.

المصدر: Leukemia [Leukemia] 2023 Feb; Vol. 37 (2), pp. 359-369. Date of Electronic Publication: 2022 Dec 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: Calreticulin*/genetics , Calreticulin*/metabolism , Proteasome Endopeptidase Complex*/metabolism , Endoplasmic Reticulum Stress*, Humans ; Cytoplasm/metabolism ; Janus Kinase 2/genetics ; Mutation ; Myeloproliferative Disorders/genetics ; Protein Serine-Threonine Kinases/genetics

المؤلفون: Jutzi JS; Brigham and Women's Hospital., Mullally A; Brigham and Women's Hospital.; Dana-Farber Cancer Institute.; Broad Institute.

المصدر: Blood [Blood] 2022 Dec 29; Vol. 140 (26), pp. 2767-2768.

نوع المنشور: Editorial; Comment

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Primary Myelofibrosis* , Neoplasms* , Myeloproliferative Disorders*, Humans ; Transforming Growth Factor beta ; Interleukin-13 ; Interleukin-4

المؤلفون: Jutzi JS; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Marneth AE; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Ciboddo M; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; The Ben May Department for Cancer Research, University of Chicago, Chicago, IL., Guerra-Moreno A; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Jiménez-Santos MJ; Bioinformatics Unit, Structural Biology Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Kosmidou A; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany., Dressman JW; Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, SC., Liang H; Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, SC., Hamel R; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; RWTH Aachen University, Aachen, Germany., Lozano P; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Rumi E; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Hematology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia, Italy., Doench JG; Broad Institute, Cambridge, MA., Gotlib J; Department of Medicine, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA., Krishnan A; Department of Pathology, Stanford Cancer Institute, Stanford University School of Medicine, Palo Alto, CA; and., Elf S; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; The Ben May Department for Cancer Research, University of Chicago, Chicago, IL., Al-Shahrour F; Bioinformatics Unit, Structural Biology Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Mullally A; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; Broad Institute, Cambridge, MA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.

المصدر: Blood [Blood] 2022 Sep 15; Vol. 140 (11), pp. 1291-1304.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Calreticulin*/genetics , Calreticulin*/metabolism , Myeloproliferative Disorders*/genetics, Animals ; Clustered Regularly Interspaced Short Palindromic Repeats ; Glucose ; Glycosylation ; Humans ; Janus Kinase 2/genetics ; Mice ; Mutation ; Receptors, Thrombopoietin/metabolism

المؤلفون: Staehle HF; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, 79098 Freiburg, Germany., Pahl HL; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, 79098 Freiburg, Germany., Jutzi JS; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, 79098 Freiburg, Germany.; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston 02115, MA, USA.

المصدر: Biomolecules [Biomolecules] 2021 Dec 20; Vol. 11 (12). Date of Electronic Publication: 2021 Dec 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

مواضيع طبية MeSH: Jumonji Domain-Containing Histone Demethylases/*metabolism , Myelodysplastic Syndromes/*metabolism , Myeloproliferative Disorders/*metabolism, Epigenesis, Genetic ; Gene Expression Regulation, Neoplastic ; Histones/metabolism ; Humans ; Methylation

المؤلفون: Jutzi JS; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Mullally A; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States.; Cancer Program, Broad Institute, Cambridge, MA, United States.

المصدر: Frontiers in immunology [Front Immunol] 2020 Aug 31; Vol. 11, pp. 2093. Date of Electronic Publication: 2020 Aug 31 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Bone Marrow*/immunology , Bone Marrow*/pathology , Hematologic Neoplasms*/genetics , Hematologic Neoplasms*/immunology , Hematologic Neoplasms*/pathology , Mutation* , Myeloproliferative Disorders*/genetics , Myeloproliferative Disorders*/immunology , Myeloproliferative Disorders*/pathology , Neoplasm Proteins*/genetics , Neoplasm Proteins*/immunology , Signal Transduction*/genetics , Signal Transduction*/immunology , Tumor Microenvironment*/genetics , Tumor Microenvironment*/immunology, Animals ; Humans

المؤلفون: Vorbach S; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Gründer A; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Zhou F; Department of Medicine, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, 69120, Heidelberg, Germany., Koellerer C; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Jutzi JS; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Simoni M; Dept. of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Giardini 1355, Modena, Italy., Riccetti L; Dept. of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Giardini 1355, Modena, Italy., Valk PJ; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands., Sanders MA; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands., Müller-Tidow C; Department of Medicine, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, 69120, Heidelberg, Germany., Nofer JR; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany., Pahl HL; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany. Heike.Pahl@uniklinik-freiburg.de., Potì F; Dept. of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Giardini 1355, Modena, Italy.; Department of Medicine and Surgery-Unit of Neurosciences, University of Parma, Via Volturno 39/F, 43125, Parma, Italy.

المصدر: Leukemia [Leukemia] 2020 Mar; Vol. 34 (3), pp. 721-734. Date of Electronic Publication: 2019 Oct 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Leukemic*, Leukemia, Myeloid, Acute/*genetics , Sphingosine-1-Phosphate Receptors/*metabolism, Animals ; Fingolimod Hydrochloride/pharmacology ; Hematopoietic Stem Cells/metabolism ; Humans ; Leukemia, Myeloid, Acute/therapy ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Mutation ; Signal Transduction ; Sphingosine-1-Phosphate Receptors/genetics ; Transcriptome ; Transgenes

المؤلفون: Staehle HF; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Baden-Württemberg, Germany., Heinemann J; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Baden-Württemberg, Germany., Gruender A; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Baden-Württemberg, Germany., Omlor AM; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Baden-Württemberg, Germany., Pahl HL; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Baden-Württemberg, Germany., Jutzi JS; Division of Molecular Hematology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Baden-Württemberg, Germany.

المصدر: PloS one [PLoS One] 2020 Feb 04; Vol. 15 (2), pp. e0228362. Date of Electronic Publication: 2020 Feb 04 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Hematopoiesis* , Mutation*, Janus Kinase 2/*genetics , Jumonji Domain-Containing Histone Demethylases/*genetics , Myeloproliferative Disorders/*genetics, Animals ; Case-Control Studies ; Cell Line, Tumor ; Embryonic Development ; Gene Knockout Techniques ; Humans ; Male ; Mice ; Mice, Knockout

المؤلفون: Afreen S; Faculty of Medicine, Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.; University of Freiburg, Freiburg, Germany., Bohler S; Faculty of Medicine, Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.; University of Freiburg, Freiburg, Germany., Müller A; Faculty of Medicine, Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany., Demmerath EM; Faculty of Medicine, Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany., Weiss JM; Faculty of Medicine, Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany., Jutzi JS; Faculty of Medicine, Section of Molecular Hematology, Department of Medicine I, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany., Schachtrup K; Faculty of Medicine, Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Freiburg, Germany., Kunze M; Faculty of Medicine, Department of Obstetrics and Gynecology, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany., Erlacher M; Faculty of Medicine, Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany. miriam.erlacher@uniklinik-freiburg.de.; German Cancer Consortium (DKTK), Freiburg, Germany and German Cancer Research Center (DKFZ), Heidelberg, Germany. miriam.erlacher@uniklinik-freiburg.de.

المصدر: Cell death & disease [Cell Death Dis] 2020 Jan 06; Vol. 11 (1), pp. 8. Date of Electronic Publication: 2020 Jan 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

مواضيع طبية MeSH: Erythropoiesis* , Hematopoietic Stem Cell Transplantation*, Hematopoietic Stem Cells/*metabolism , bcl-X Protein/*metabolism, Animals ; Antigens, CD34/metabolism ; Bcl-2-Like Protein 11/metabolism ; Benzothiazoles/pharmacology ; Erythroid Cells/drug effects ; Erythroid Cells/metabolism ; Gene Knockdown Techniques ; Humans ; Isoquinolines/pharmacology ; Mice ; Transplantation, Heterologous