المؤلفون: Dirk Nierhoff, Marina Vogel, Tom H. Karlsen, Jan-Philipp Mallm, Katharina Fuchs, Gisela Gabernet, Caroline Klindt, Karl Köhrer, Michael Trauner, Dieter Häussinger, Tom Luedde, Claudia D. Fuchs, Irene Esposito, Jan Stindt, Kristina Schoonjans, María García-Beccaria, Peter Fickert, Johanna Höhne, Tobias Lautwein, Evaggelia Liaskou, Sofia Ferreira-Gonzalez, M Reich, Joanne Verheij, Lina Spomer, Johannes R. Hov, Ulrich Beuers, Verena Keitel, Mathias Heikenwalder, Stuart J. Forbes, Sven Nahnsen, Christoph Schramm, K Deutschmann, Gideon M. Hirschfield

المساهمون: Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Pathology

المصدر: Journal of hepatology, 75(3), 634-646. Elsevier
Reich, M, Spomer, L, Klindt, C, Fuchs, K, Stindt, J, Deutschmann, K, Höhne, J, Liaskou, E, Hov, J R, Karlsen, T H, Beuers, U, Verheij, J, Ferreira-Gonzalez, S, Hirschfield, G, Forbes, S J, Schramm, C, Esposito, I, Nierhoff, D, Fickert, P, Fuchs, C D, Trauner, M, García-Beccaria, M, Gabernet, G, Nahnsen, S, Mallm, J-P, Vogel, M, Schoonjans, K, Lautwein, T, Koehrer, K, Häussinger, D, Luedde, T, Heikenwalder, M & Keitel, V 2021, ' Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis ', Journal of Hepatology . https://doi.org/10.1016/j.jhep.2021.03.029

مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, Virulence Factors, medicine.drug_class, Cholangitis, Sclerosing, education, Down-Regulation, determines, digestive system, Receptors, G-Protein-Coupled, Primary sclerosing cholangitis, murine model, Biliary injury, Pathogenesis, scrna-seq, Mice, 03 medical and health sciences, 0302 clinical medicine, biliary damage, Fibrosis, expression, parasitic diseases, medicine, Animals, Interleukin 8, cholangiocytes, Biliary Tract, norursodeoxycholic acid, health care economics and organizations, disease, Hepatology, Bile acid, biliary organoids, Chemistry, Bile duct, interleukin-8, Epithelial Cells, hco3-umbrella, medicine.disease, G protein-coupled bile acid receptor, bile acid receptor, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, bile-acid receptor, Liver, norudca, 030211 gastroenterology & hepatology

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02c374f29995d64c84328b525e4acb7
http://hdl.handle.net/10852/92295

المؤلفون: K Deutschmann, Verena Keitel, Christoph G. W. Gertzen, Roland P. Piekorz, Alexander Lang, Holger Gohlke, M Reich, Dieter Häussinger, Tom Luedde

المصدر: 37. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber.

مصطلحات موضوعية: Chemistry, Cancer research, G protein-coupled bile acid receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::916abdcca947be5a60b64eedaeafb170
https://doi.org/10.1055/s-0040-1722044

المؤلفون: K Deutschmann, Christoph G. W. Gertzen, M Reich, Christina Wöhler, Verena Keitel, Caroline Klindt, Dieter Häussinger, Holger Gohlke, Sven Schäfer

المصدر: Mammalian Sterols ISBN: 9783030396831

مصطلحات موضوعية: biology, Cell surface receptor, Chemistry, Kinase, biology.protein, Adenylate kinase, Epidermal growth factor receptor, Cyclase, G protein-coupled bile acid receptor, Intracellular, Proto-oncogene tyrosine-protein kinase Src, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::af6685bdd16fb9a2adfad91e3bc19465
https://doi.org/10.1007/978-3-030-39684-8_4

المؤلفون: Roland P. Piekorz, M Reich, K Deutschmann, Dieter Häussinger, Verena Keitel, Alexander Lang

المصدر: Zeitschrift für Gastroenterologie. 56:E2-E89

مصطلحات موضوعية: Chemistry, Gastroenterology, Cancer research, G protein-coupled bile acid receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::38305039afc61b94e7a5ef89e4254414
https://doi.org/10.1055/s-0037-1612786

المؤلفون: M Reich, Diran Herebian, Ertan Mayatepek, Dieter Häussinger, Caroline Klindt, Verena Keitel, K Deutschmann

المصدر: Zeitschrift für Gastroenterologie. 54:1343-1404

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Internal medicine, Gastroenterology, medicine, Portal hypertension, Liver damage, medicine.disease, business, G protein-coupled bile acid receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::91b011a34fd12d8dc529f8d4c1560ae8
https://doi.org/10.1055/s-0036-1597447

المؤلفون: K Deutschmann, M Reich, A Lang, R Piekorz, C Gertzen, H Gohlke, D Häussinger, V Keitel

المصدر: 35. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ed51cf651c2ce5faa34f62aee5f06d23
https://doi.org/10.1055/s-0038-1677201

المؤلفون: Jan Stindt, K Deutschmann, Verena Keitel, Pa Lang, Dieter Häussinger, M Reich

المصدر: 35. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber.

مصطلحات موضوعية: chemistry.chemical_compound, Downregulation and upregulation, Lipopolysaccharide, chemistry, Listeria monocytogenes, medicine, Liver damage, medicine.disease_cause, G protein-coupled bile acid receptor, Microbiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::23ca584a09edabb74fe7a586bc170952
https://doi.org/10.1055/s-0038-1677097

المؤلفون: Annika Sommerfeld, Ertan Mayatepek, Caroline Klindt, K Deutschmann, Diran Herebian, Verena Keitel, Stefanie Kluge, M Reich, Wolfram T. Knoefel, Ralf Kubitz, Dieter Häussinger, Christoph Ullmer

المصدر: Gut. 65:487-501

مصطلحات موضوعية: Male, 0301 basic medicine, MAPK/ERK pathway, medicine.medical_specialty, Cholangiocyte proliferation, Apoptosis, Receptors, G-Protein-Coupled, Bile Acids and Salts, Cholangiocarcinoma, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Internal medicine, medicine, Animals, Humans, Epidermal growth factor receptor, Ligation, Cell Proliferation, Common Bile Duct, Mice, Knockout, biology, Cell growth, Gastroenterology, Fas receptor, G protein-coupled bile acid receptor, Cell biology, 030104 developmental biology, Endocrinology, Bile Duct Neoplasms, chemistry, biology.protein, 030211 gastroenterology & hepatology, Taurolithocholic acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6182f78d98581564889d2ac1a0946776
https://doi.org/10.1136/gutjnl-2015-309458

المؤلفون: Caroline Klindt, Dieter Häussinger, Verena Keitel, Lina Spomer, Carola Dröge, K Deutschmann, M Reich

المصدر: Biochimica et biophysica acta. Molecular basis of disease. 1864(4 Pt)

مصطلحات موضوعية: 0301 basic medicine, Choleretic, medicine.drug_class, Cholangitis, Cholangiocyte proliferation, Physiology, Biology, Primary sclerosing cholangitis, Receptors, G-Protein-Coupled, Bile Acids and Salts, 03 medical and health sciences, Cholestasis, medicine, Animals, Humans, Genetic Predisposition to Disease, Molecular Biology, Cell Proliferation, Mice, Knockout, Bile acid, Cysts, Liver Diseases, Epithelial Cells, medicine.disease, G protein-coupled bile acid receptor, Bicarbonates, Disease Models, Animal, 030104 developmental biology, Liver, Hepatic stellate cell, Molecular Medicine, Farnesoid X receptor, Bile Ducts, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcb2791fafaf495f3a527f7c41a7e5f
https://pubmed.ncbi.nlm.nih.gov/28844960

المؤلفون: Lina Spomer, Caroline Klindt, M Reich, Dieter Häussinger, K Deutschmann, Verena Keitel

المصدر: Digestive diseases (Basel, Switzerland). 35(3)

مصطلحات موضوعية: 0301 basic medicine, business.industry, Liver Diseases, Gastroenterology, General Medicine, medicine.disease, G protein-coupled bile acid receptor, Models, Biological, Receptors, G-Protein-Coupled, Bile Acids and Salts, 03 medical and health sciences, 030104 developmental biology, Cholestasis, Biochemistry, Cell surface receptor, medicine, Animals, Humans, Farnesoid X receptor, Peroxisome proliferator-activated receptor alpha, CYP8B1, Receptor, business, G protein-coupled receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6599aa73932c47491116e45d7bb032e7
https://pubmed.ncbi.nlm.nih.gov/28249265